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The map label for this gene is engA [H]

Identifier: 220904745

GI number: 220904745

Start: 1767304

End: 1768668

Strand: Direct

Name: engA [H]

Synonym: Ddes_1477

Alternate gene names: 220904745

Gene position: 1767304-1768668 (Clockwise)

Preceding gene: 220904744

Following gene: 220904746

Centisome position: 61.5

GC content: 60.07

Gene sequence:

>1365_bases
ATGGCTGAAACTCTACCCCGCATCATTCTCGTGGGTCGCCCCAATGTGGGCAAGTCCACCCTGTTCAACCGCCTCATCCG
CAGCAACCGCGCCATCACCCACGACCGCCCCGGCGTCACCCGCGACCGCATGGAAGGGGTGGTGCGCCGCAAGGGACTGC
CGGCCTTCGGTATTGTAGACACAGGCGGCATCACCCTTGACGCCCATGCCATGGTCGTTGAAGGTCCCGAAGGCATCCGC
GGCTTTGAGCAGGATATCCTCGACCAGACCGAGGCCGCCATGAAAGACGCTGCGGCTGTGGCCTTTGTGGTAGACGGCCG
CGACGGCCTGCTGCCGCTGGACGAGCACCTTGCCGCCCACGTGCGCCGCAAGGGCCTGCCCACCATTTGCGTTGTCAACA
AGGTGGACGGAGCCGAACGCGAAGACGAACAGCTGGCAGAATTTCACATACTGGGCTTTCCCCTGTTGGCTGTCTCTGCC
GAGCACGGGCACAATATCCGCGCCCTTGTGGAGGATCTGGCCGACCTGCTGCCCGAAGAGTCTTCCGAAGAGCCTCCGGC
CCCCCCGGCGCTGCGCCTGGCCATGCTCGGCCGCCCCAATGCGGGCAAGTCTTCGCTCATCAACGCCCTTTCCGGCGAAG
AGCGCATGATCGTTTCCGATGTGGCCGGCACCACCCGCGACAGCGTTGACGTACGCTTCTGCCGTAATGGCAAGGACTAT
GTCTTTGTTGACACGGCCGGTGTCCGGCGGCGCACCAAAATCACAGACAGCGTAGAGAAATACTCTGTAAATTCGGCCAT
CAAATCCAGCACAAAGGCAGATGTGACCCTGCTGACCCTGGATGCGGCCGAAGGCGTGAGCCAGCAGGACAAACGCCTGA
TGGACATGCTTAATACCCGTAAAACGCCGTTTATGGTCCTTATCAACAAGTGTGACCTCGCCCCCCGGAACGCTCTGGAC
CAACTGAAAAAAAATATCAGCCAGATGCTGGCATTCTGCCCCCATGTGCCGGTCATGCCCGTTTCCGCTCTTACCGGCAA
AGATCTGGAAAAAATACTGCCTCTGGCGCAACGCATTCACGAAGAATGCAGCATCCGCATCCCCACAGGACGACTCAACA
GGGCTATGGAAGAAGTGCTTACCCGCCACCAGCCTCCTGTGGTCAAAAGGGCGCGGGCCAAATTTTTCTATCTCACCCAG
GCCGAATCCGAGCCGCCGACGTTTGTCTTCTTTGTGAGCGACGCCACGCGCGTACCCGAGAGCTATAGCCGCTACCTTGA
GCGCGCGCTGCGAAAGATTTTCGGCATCGTCCATGCGCCCATGCGCCTGCACCTGCGGTCCAGCCACAAGAAAAAAGAGA
AATAG

Upstream 100 bases:

>100_bases
CAATTTCTCTTTTACATTAGGGTCCGCACAGGCGGGCCTTTCAAAAAGCGCCCCGCGAGAGCCCGCCGCCTTGCGTCAGG
GACGCAACAAGGTTACCGCC

Downstream 100 bases:

>100_bases
ACCGGCCATTACGCGTAAAAAACTGCCCGAAAGCGAAAAAACATCCTGTTTTTCACGAGGCGGCCCAGATGCATTTGCAG
CATCCGGGCCGCCTCTGCCG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MAETLPRIILVGRPNVGKSTLFNRLIRSNRAITHDRPGVTRDRMEGVVRRKGLPAFGIVDTGGITLDAHAMVVEGPEGIR
GFEQDILDQTEAAMKDAAAVAFVVDGRDGLLPLDEHLAAHVRRKGLPTICVVNKVDGAEREDEQLAEFHILGFPLLAVSA
EHGHNIRALVEDLADLLPEESSEEPPAPPALRLAMLGRPNAGKSSLINALSGEERMIVSDVAGTTRDSVDVRFCRNGKDY
VFVDTAGVRRRTKITDSVEKYSVNSAIKSSTKADVTLLTLDAAEGVSQQDKRLMDMLNTRKTPFMVLINKCDLAPRNALD
QLKKNISQMLAFCPHVPVMPVSALTGKDLEKILPLAQRIHEECSIRIPTGRLNRAMEEVLTRHQPPVVKRARAKFFYLTQ
AESEPPTFVFFVSDATRVPESYSRYLERALRKIFGIVHAPMRLHLRSSHKKKEK

Sequences:

>Translated_454_residues
MAETLPRIILVGRPNVGKSTLFNRLIRSNRAITHDRPGVTRDRMEGVVRRKGLPAFGIVDTGGITLDAHAMVVEGPEGIR
GFEQDILDQTEAAMKDAAAVAFVVDGRDGLLPLDEHLAAHVRRKGLPTICVVNKVDGAEREDEQLAEFHILGFPLLAVSA
EHGHNIRALVEDLADLLPEESSEEPPAPPALRLAMLGRPNAGKSSLINALSGEERMIVSDVAGTTRDSVDVRFCRNGKDY
VFVDTAGVRRRTKITDSVEKYSVNSAIKSSTKADVTLLTLDAAEGVSQQDKRLMDMLNTRKTPFMVLINKCDLAPRNALD
QLKKNISQMLAFCPHVPVMPVSALTGKDLEKILPLAQRIHEECSIRIPTGRLNRAMEEVLTRHQPPVVKRARAKFFYLTQ
AESEPPTFVFFVSDATRVPESYSRYLERALRKIFGIVHAPMRLHLRSSHKKKEK
>Mature_453_residues
AETLPRIILVGRPNVGKSTLFNRLIRSNRAITHDRPGVTRDRMEGVVRRKGLPAFGIVDTGGITLDAHAMVVEGPEGIRG
FEQDILDQTEAAMKDAAAVAFVVDGRDGLLPLDEHLAAHVRRKGLPTICVVNKVDGAEREDEQLAEFHILGFPLLAVSAE
HGHNIRALVEDLADLLPEESSEEPPAPPALRLAMLGRPNAGKSSLINALSGEERMIVSDVAGTTRDSVDVRFCRNGKDYV
FVDTAGVRRRTKITDSVEKYSVNSAIKSSTKADVTLLTLDAAEGVSQQDKRLMDMLNTRKTPFMVLINKCDLAPRNALDQ
LKKNISQMLAFCPHVPVMPVSALTGKDLEKILPLAQRIHEECSIRIPTGRLNRAMEEVLTRHQPPVVKRARAKFFYLTQA
ESEPPTFVFFVSDATRVPESYSRYLERALRKIFGIVHAPMRLHLRSSHKKKEK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=470, Percent_Identity=35.7446808510638, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI2367268, Length=127, Percent_Identity=35.4330708661417, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788919, Length=183, Percent_Identity=29.5081967213115, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17507259, Length=131, Percent_Identity=32.0610687022901, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=167, Percent_Identity=29.3413173652695, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI45550813, Length=169, Percent_Identity=34.9112426035503, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50331; Mature: 50200

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETLPRIILVGRPNVGKSTLFNRLIRSNRAITHDRPGVTRDRMEGVVRRKGLPAFGIVD
CCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEE
TGGITLDAHAMVVEGPEGIRGFEQDILDQTEAAMKDAAAVAFVVDGRDGLLPLDEHLAAH
CCCEEEECEEEEEECCHHCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHH
VRRKGLPTICVVNKVDGAEREDEQLAEFHILGFPLLAVSAEHGHNIRALVEDLADLLPEE
HHHCCCCEEEEEECCCCCCCCHHHHHHHHHCCCHHEEEECCCCCCHHHHHHHHHHHCCCC
SSEEPPAPPALRLAMLGRPNAGKSSLINALSGEERMIVSDVAGTTRDSVDVRFCRNGKDY
CCCCCCCCHHHEEEECCCCCCCHHHHHHHHCCCCEEEEEHHCCCCCCCCEEEEECCCCCE
VFVDTAGVRRRTKITDSVEKYSVNSAIKSSTKADVTLLTLDAAEGVSQQDKRLMDMLNTR
EEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCC
KTPFMVLINKCDLAPRNALDQLKKNISQMLAFCPHVPVMPVSALTGKDLEKILPLAQRIH
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHH
EECSIRIPTGRLNRAMEEVLTRHQPPVVKRARAKFFYLTQAESEPPTFVFFVSDATRVPE
HHCEEECCCHHHHHHHHHHHHCCCCCHHHHHCCEEEEEEECCCCCCEEEEEECCCCCCCH
SYSRYLERALRKIFGIVHAPMRLHLRSSHKKKEK
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
AETLPRIILVGRPNVGKSTLFNRLIRSNRAITHDRPGVTRDRMEGVVRRKGLPAFGIVD
CCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEE
TGGITLDAHAMVVEGPEGIRGFEQDILDQTEAAMKDAAAVAFVVDGRDGLLPLDEHLAAH
CCCEEEECEEEEEECCHHCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHH
VRRKGLPTICVVNKVDGAEREDEQLAEFHILGFPLLAVSAEHGHNIRALVEDLADLLPEE
HHHCCCCEEEEEECCCCCCCCHHHHHHHHHCCCHHEEEECCCCCCHHHHHHHHHHHCCCC
SSEEPPAPPALRLAMLGRPNAGKSSLINALSGEERMIVSDVAGTTRDSVDVRFCRNGKDY
CCCCCCCCHHHEEEECCCCCCCHHHHHHHHCCCCEEEEEHHCCCCCCCCEEEEECCCCCE
VFVDTAGVRRRTKITDSVEKYSVNSAIKSSTKADVTLLTLDAAEGVSQQDKRLMDMLNTR
EEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCC
KTPFMVLINKCDLAPRNALDQLKKNISQMLAFCPHVPVMPVSALTGKDLEKILPLAQRIH
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHH
EECSIRIPTGRLNRAMEEVLTRHQPPVVKRARAKFFYLTQAESEPPTFVFFVSDATRVPE
HHCEEECCCHHHHHHHHHHHHCCCCCHHHHHCCEEEEEEECCCCCCEEEEEECCCCCCCH
SYSRYLERALRKIFGIVHAPMRLHLRSSHKKKEK
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA