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The map label for this gene is rfbG [H]

Identifier: 220904149

GI number: 220904149

Start: 1024883

End: 1025998

Strand: Reverse

Name: rfbG [H]

Synonym: Ddes_0876

Alternate gene names: 220904149

Gene position: 1025998-1024883 (Counterclockwise)

Preceding gene: 220904150

Following gene: 220904148

Centisome position: 35.71

GC content: 60.84

Gene sequence:

>1116_bases
ATGTTTGCCAATGCATATAAGGGACGCCGGGTTTTCGTAACCGGGCACACGGGTTTCAAAGGTTCCTGGATGGCCGCGTG
GCTAAGCCAGCTCGGTGCTGTGGTGGGCGGTTTTTCCGACGATGTACCCACCGAACCTTCTCACTATGCCGCAATGAATC
TGGGTGCGCACCTTGAGGCCGACCTGCGCGGCGACATACGCGACCGCGATGCTGTGGTGCGCGCGGTGCGCCAGTTTCGC
CCGGATGTGGTTTTTCATCTTGCCGCCCAGGCGCTTGTACGCAAGTCCTATGATGATCCGGCCCTGACATTTGAGGCCAA
CATGATGGGAACCCTCAATGTGCTGGAAGCTGTGCGCGCCTGCCCGGACGTGAGCGCGGCCGTGATGATAACCTCTGACA
AGTGCTACAGAAATGATGAATGGGTTTGGGGCTATCGTGAAACCGACCACTTGGGCGGGCACGACCCCTACTCTGCCTCC
AAGGGCTGCGCCGAAATCATCGCTCACTCCTATTTTGAAAGTTTTTTCAAGGATGGCCCTGCCTGCGCCACGGTTCGGGC
GGGCAACGTCATCGGCGGCGGCGACTGGGCCGTTGACCGCATCGTGCCCGATTGCGCCCGTGCCTGGGCTGCGGGACAGG
CAGTGCAGATACGCAGCCCCTGGGCCACCCGCCCCTGGCAGCTCGTGCTTGAACCCCTGTCCGGCTATCTGTGGCTGGGC
GCACGCCTGCTGCTCGGCCAAAACAGCCCCTTTGACCTGCGCGGTCAGGCCTACAACTTTGGCCCCGCCGCTGACGTCAA
CAATACGGTGGCCGAGGTGGTGGACGCCCTGGCCCTGCACTGGCCCGGCTTTGCCAGTGAAATGGACAAGGCCGGACAGG
CGGGCATGAAAGAATGCACCCTGCTCAAGCTCTGCTGCGACAAGGCCCTTGCCCACCTGGGCTGGAAGGCCACCCTCAAC
TTTGAGGAAACCATCCGCTATACTGCCGAATGGTATCATTGCTTCTATCAGGGCGTTGGCGGCAAAAAACCGCAAAACAT
GCTGGATTTCACCCTTGGGCAGATCGCAGCCTACGTCAATGCCGCCGAACAGCGCGGCCAGCTCTGGATAAAGTAG

Upstream 100 bases:

>100_bases
ATGGCCCGCCGGGCTGTGCAGGCCCCGCACCCGGCCTGTCCTGCGCTGCATATGCGCGGCTGCGCGCGGATACAGCAAGA
AATTATTGTGAGGAACACAT

Downstream 100 bases:

>100_bases
CATGAACGCCCTCGAAACCGTGGCCCGGAATGTGGGCATTGACGGGGCACTGCTGCAATCACTGGGAATAATTCCCACAC
CCGGCGGACCGGTGCTGCAC

Product: CDP-glucose 4,6-dehydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MFANAYKGRRVFVTGHTGFKGSWMAAWLSQLGAVVGGFSDDVPTEPSHYAAMNLGAHLEADLRGDIRDRDAVVRAVRQFR
PDVVFHLAAQALVRKSYDDPALTFEANMMGTLNVLEAVRACPDVSAAVMITSDKCYRNDEWVWGYRETDHLGGHDPYSAS
KGCAEIIAHSYFESFFKDGPACATVRAGNVIGGGDWAVDRIVPDCARAWAAGQAVQIRSPWATRPWQLVLEPLSGYLWLG
ARLLLGQNSPFDLRGQAYNFGPAADVNNTVAEVVDALALHWPGFASEMDKAGQAGMKECTLLKLCCDKALAHLGWKATLN
FEETIRYTAEWYHCFYQGVGGKKPQNMLDFTLGQIAAYVNAAEQRGQLWIK

Sequences:

>Translated_371_residues
MFANAYKGRRVFVTGHTGFKGSWMAAWLSQLGAVVGGFSDDVPTEPSHYAAMNLGAHLEADLRGDIRDRDAVVRAVRQFR
PDVVFHLAAQALVRKSYDDPALTFEANMMGTLNVLEAVRACPDVSAAVMITSDKCYRNDEWVWGYRETDHLGGHDPYSAS
KGCAEIIAHSYFESFFKDGPACATVRAGNVIGGGDWAVDRIVPDCARAWAAGQAVQIRSPWATRPWQLVLEPLSGYLWLG
ARLLLGQNSPFDLRGQAYNFGPAADVNNTVAEVVDALALHWPGFASEMDKAGQAGMKECTLLKLCCDKALAHLGWKATLN
FEETIRYTAEWYHCFYQGVGGKKPQNMLDFTLGQIAAYVNAAEQRGQLWIK
>Mature_371_residues
MFANAYKGRRVFVTGHTGFKGSWMAAWLSQLGAVVGGFSDDVPTEPSHYAAMNLGAHLEADLRGDIRDRDAVVRAVRQFR
PDVVFHLAAQALVRKSYDDPALTFEANMMGTLNVLEAVRACPDVSAAVMITSDKCYRNDEWVWGYRETDHLGGHDPYSAS
KGCAEIIAHSYFESFFKDGPACATVRAGNVIGGGDWAVDRIVPDCARAWAAGQAVQIRSPWATRPWQLVLEPLSGYLWLG
ARLLLGQNSPFDLRGQAYNFGPAADVNNTVAEVVDALALHWPGFASEMDKAGQAGMKECTLLKLCCDKALAHLGWKATLN
FEETIRYTAEWYHCFYQGVGGKKPQNMLDFTLGQIAAYVNAAEQRGQLWIK

Specific function: INVOLVED IN THE SYNTHESIS OF ENTEROBACTERIAL COMMON ANTIGEN (ECA) AND REQUIRED FOR SYNTHESIS OF LIPOPOLYSACCHARIDE O-SIDE CHAINS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI48994969, Length=347, Percent_Identity=25.3602305475504, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013445
- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =4.2.1.45 [H]

Molecular weight: Translated: 40835; Mature: 40835

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFANAYKGRRVFVTGHTGFKGSWMAAWLSQLGAVVGGFSDDVPTEPSHYAAMNLGAHLEA
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCEEC
DLRGDIRDRDAVVRAVRQFRPDVVFHLAAQALVRKSYDDPALTFEANMMGTLNVLEAVRA
CCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHH
CPDVSAAVMITSDKCYRNDEWVWGYRETDHLGGHDPYSASKGCAEIIAHSYFESFFKDGP
CCCCCEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
ACATVRAGNVIGGGDWAVDRIVPDCARAWAAGQAVQIRSPWATRPWQLVLEPLSGYLWLG
CEEEEECCCEECCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHH
ARLLLGQNSPFDLRGQAYNFGPAADVNNTVAEVVDALALHWPGFASEMDKAGQAGMKECT
HHHEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHH
LLKLCCDKALAHLGWKATLNFEETIRYTAEWYHCFYQGVGGKKPQNMLDFTLGQIAAYVN
HHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
AAEQRGQLWIK
HHHHCCCEECC
>Mature Secondary Structure
MFANAYKGRRVFVTGHTGFKGSWMAAWLSQLGAVVGGFSDDVPTEPSHYAAMNLGAHLEA
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCEEC
DLRGDIRDRDAVVRAVRQFRPDVVFHLAAQALVRKSYDDPALTFEANMMGTLNVLEAVRA
CCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHH
CPDVSAAVMITSDKCYRNDEWVWGYRETDHLGGHDPYSASKGCAEIIAHSYFESFFKDGP
CCCCCEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
ACATVRAGNVIGGGDWAVDRIVPDCARAWAAGQAVQIRSPWATRPWQLVLEPLSGYLWLG
CEEEEECCCEECCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHH
ARLLLGQNSPFDLRGQAYNFGPAADVNNTVAEVVDALALHWPGFASEMDKAGQAGMKECT
HHHEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHH
LLKLCCDKALAHLGWKATLNFEETIRYTAEWYHCFYQGVGGKKPQNMLDFTLGQIAAYVN
HHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
AAEQRGQLWIK
HHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1710759; 11677609 [H]