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The map label for this gene is tolC [H]

Identifier: 220904136

GI number: 220904136

Start: 1010939

End: 1012369

Strand: Direct

Name: tolC [H]

Synonym: Ddes_0863

Alternate gene names: 220904136

Gene position: 1010939-1012369 (Clockwise)

Preceding gene: 220904127

Following gene: 220904137

Centisome position: 35.18

GC content: 58.07

Gene sequence:

>1431_bases
GTGATTCGCTCGTCTGCTCTTTCTCTTGTTATTCTGGCTGTCTTTCTCTGTACCTCTTCCGCTGCTGCAAGCCGTAATAC
GGCATCCGGGGCTGCGGTTCCCCTTTTTCAAGGGCAGCGCAGCCTTGGCGGCCAGAATGGAGCAGGGGCAGAAGCCACGG
GCGGCCAGCCTGGCGGCGTACGCGGCATCACCATGCTGGATGCGGTGAATCAGGCTCTGGAGCATAATCCGAGTCTGGGT
TCGCAGGAGGCGCAGGGCCGCTCATCTGAAGAAAGCCGCAAGTCTGCCCGGGGATCCTTTGGTCCCAGGCTTGGCATGAC
ATACTCGGTTGCCAAGCAGGAAAGAGACAGCACCGTGCGCAACACCGACCCGCCTAAAATGGGTACATACAGTTGGGGCG
TGGAGGTTTCTCAGCCGGTTTTTCAGGGGTTTCGCCTGCTGGCAAATTACCAGAAAGCGGCCTTGCAGGCTGATAGTGAC
AAGGCGGCATTGCGCAATGCCGAGCTTGCCATGACAGAGCAGGTGCAGACCCAGTTTCTGAATTTCTTGCGATATGACGA
AAGTGTGCGCAGTGAACGTGACGCCCTTGCGCGTTTGCGCGACCAGCTCCGCATCACCACGGCTTTTTTTGATGTGGGAC
TTCGCCCGCGTCTGGATGTACTGCAGGCCGAAGTGGACGTGCGGCAGGCTGAGAATGCGGTGATCAAGGCTGAAAACAGC
CGAGACACAAGCCTGGCAAAGCTGAACACCCTGCTGGGCTTTTCGGCCACGGCGGGGGTGGGATATACGGGGCAGCTGGC
CCATGTGCCGTTCACACGCTCCCTTGAGCAATGCCTCGAAGCGGCATACCGGCAACGGCCGGACATCTATATGGCCGCAA
AATCTGTGGAAATTGCGGGCAAAAGCCAGCAGGCCGTGCAGAGCGACTACTACCCGCAGGTTGAGGCCTATTATAATGTA
ACCCAGAGCGGCAATACCCCTGATCTTCAGAAAGACGGCGCCAGCGGTTCCCGCACACAGACCTGGGAAGTGGGCGCGCG
TGCCACCTGGAACGCTTTTCAGTGGGGCACGACCTATTATGCCGACAAGGAAGCCGGCTGGCTTGTAACCAAGATGCGCT
ATGAGGCCGAAAACCTGAAGCTCAATGTTGGTTACGACATCAAGTCCAAGCTTCTTGCCGTGCATGAAGCGGAAAAGCGC
ATCAATGTGGCGGAAAAGGCCGTAGAGCAGGCCACCGAGGCGTATAATGTGGCTCTGGCCCGCTACCAGGAGCAGGTGGG
CACAAACTTTGACGTGCTGGACGCCTCATCCAAACTTACTTCGGCCCAGGCTTCGCTTACGGGCGCCAAGGCCGACTATC
TTACAGCCCTGTCCCAATTGTATGTGGCCATGGGCGAATTTAAACCTGACCTGATGCGGCGCGACCGGTAA

Upstream 100 bases:

>100_bases
CAATGCTGTGCCGGGCGTTGTATGAAGAGCCATGCGATGTTCGTCCTCTCCATGCGCCTGTCTGAAGGCGCGTGTCACTT
TCTCAAGAACGGCGGTTTCA

Downstream 100 bases:

>100_bases
ACGGCTTCGCGCCCAAGCACAAGCGATAGAGGAATGAAAGAACCCTACCTTACCATCACGCCCCTGGGGGGCCTTGGAGA
AATCGGCCTCAACTGCCAAT

Product: outer membrane efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MIRSSALSLVILAVFLCTSSAAASRNTASGAAVPLFQGQRSLGGQNGAGAEATGGQPGGVRGITMLDAVNQALEHNPSLG
SQEAQGRSSEESRKSARGSFGPRLGMTYSVAKQERDSTVRNTDPPKMGTYSWGVEVSQPVFQGFRLLANYQKAALQADSD
KAALRNAELAMTEQVQTQFLNFLRYDESVRSERDALARLRDQLRITTAFFDVGLRPRLDVLQAEVDVRQAENAVIKAENS
RDTSLAKLNTLLGFSATAGVGYTGQLAHVPFTRSLEQCLEAAYRQRPDIYMAAKSVEIAGKSQQAVQSDYYPQVEAYYNV
TQSGNTPDLQKDGASGSRTQTWEVGARATWNAFQWGTTYYADKEAGWLVTKMRYEAENLKLNVGYDIKSKLLAVHEAEKR
INVAEKAVEQATEAYNVALARYQEQVGTNFDVLDASSKLTSAQASLTGAKADYLTALSQLYVAMGEFKPDLMRRDR

Sequences:

>Translated_476_residues
MIRSSALSLVILAVFLCTSSAAASRNTASGAAVPLFQGQRSLGGQNGAGAEATGGQPGGVRGITMLDAVNQALEHNPSLG
SQEAQGRSSEESRKSARGSFGPRLGMTYSVAKQERDSTVRNTDPPKMGTYSWGVEVSQPVFQGFRLLANYQKAALQADSD
KAALRNAELAMTEQVQTQFLNFLRYDESVRSERDALARLRDQLRITTAFFDVGLRPRLDVLQAEVDVRQAENAVIKAENS
RDTSLAKLNTLLGFSATAGVGYTGQLAHVPFTRSLEQCLEAAYRQRPDIYMAAKSVEIAGKSQQAVQSDYYPQVEAYYNV
TQSGNTPDLQKDGASGSRTQTWEVGARATWNAFQWGTTYYADKEAGWLVTKMRYEAENLKLNVGYDIKSKLLAVHEAEKR
INVAEKAVEQATEAYNVALARYQEQVGTNFDVLDASSKLTSAQASLTGAKADYLTALSQLYVAMGEFKPDLMRRDR
>Mature_476_residues
MIRSSALSLVILAVFLCTSSAAASRNTASGAAVPLFQGQRSLGGQNGAGAEATGGQPGGVRGITMLDAVNQALEHNPSLG
SQEAQGRSSEESRKSARGSFGPRLGMTYSVAKQERDSTVRNTDPPKMGTYSWGVEVSQPVFQGFRLLANYQKAALQADSD
KAALRNAELAMTEQVQTQFLNFLRYDESVRSERDALARLRDQLRITTAFFDVGLRPRLDVLQAEVDVRQAENAVIKAENS
RDTSLAKLNTLLGFSATAGVGYTGQLAHVPFTRSLEQCLEAAYRQRPDIYMAAKSVEIAGKSQQAVQSDYYPQVEAYYNV
TQSGNTPDLQKDGASGSRTQTWEVGARATWNAFQWGTTYYADKEAGWLVTKMRYEAENLKLNVGYDIKSKLLAVHEAEKR
INVAEKAVEQATEAYNVALARYQEQVGTNFDVLDASSKLTSAQASLTGAKADYLTALSQLYVAMGEFKPDLMRRDR

Specific function: May be specialized for signal sequence independent, extracellular secretion in Gram-negative bacteria [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010130 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 51962; Mature: 51962

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS00539 PYROKININ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRSSALSLVILAVFLCTSSAAASRNTASGAAVPLFQGQRSLGGQNGAGAEATGGQPGGV
CCCHHHHHHHHHHHHHHCCCHHCCCCCCCCCEEEHCCCHHHCCCCCCCCCCCCCCCCCCC
RGITMLDAVNQALEHNPSLGSQEAQGRSSEESRKSARGSFGPRLGMTYSVAKQERDSTVR
CHHHHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCC
NTDPPKMGTYSWGVEVSQPVFQGFRLLANYQKAALQADSDKAALRNAELAMTEQVQTQFL
CCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHH
NFLRYDESVRSERDALARLRDQLRITTAFFDVGLRPRLDVLQAEVDVRQAENAVIKAENS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEECCC
RDTSLAKLNTLLGFSATAGVGYTGQLAHVPFTRSLEQCLEAAYRQRPDIYMAAKSVEIAG
CCHHHHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCCCEEEEECEEEECC
KSQQAVQSDYYPQVEAYYNVTQSGNTPDLQKDGASGSRTQTWEVGARATWNAFQWGTTYY
CCHHHHHHCCCCCEEHEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCEECCCEEE
ADKEAGWLVTKMRYEAENLKLNVGYDIKSKLLAVHEAEKRINVAEKAVEQATEAYNVALA
ECCCCCEEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYQEQVGTNFDVLDASSKLTSAQASLTGAKADYLTALSQLYVAMGEFKPDLMRRDR
HHHHHHCCCCEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure
MIRSSALSLVILAVFLCTSSAAASRNTASGAAVPLFQGQRSLGGQNGAGAEATGGQPGGV
CCCHHHHHHHHHHHHHHCCCHHCCCCCCCCCEEEHCCCHHHCCCCCCCCCCCCCCCCCCC
RGITMLDAVNQALEHNPSLGSQEAQGRSSEESRKSARGSFGPRLGMTYSVAKQERDSTVR
CHHHHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCC
NTDPPKMGTYSWGVEVSQPVFQGFRLLANYQKAALQADSDKAALRNAELAMTEQVQTQFL
CCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHH
NFLRYDESVRSERDALARLRDQLRITTAFFDVGLRPRLDVLQAEVDVRQAENAVIKAENS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEECCC
RDTSLAKLNTLLGFSATAGVGYTGQLAHVPFTRSLEQCLEAAYRQRPDIYMAAKSVEIAG
CCHHHHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCCCEEEEECEEEECC
KSQQAVQSDYYPQVEAYYNVTQSGNTPDLQKDGASGSRTQTWEVGARATWNAFQWGTTYY
CCHHHHHHCCCCCEEHEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCEECCCEEE
ADKEAGWLVTKMRYEAENLKLNVGYDIKSKLLAVHEAEKRINVAEKAVEQATEAYNVALA
ECCCCCEEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYQEQVGTNFDVLDASSKLTSAQASLTGAKADYLTALSQLYVAMGEFKPDLMRRDR
HHHHHHCCCCEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]