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The map label for this gene is nanR [H]

Identifier: 220904127

GI number: 220904127

Start: 1001155

End: 1001940

Strand: Direct

Name: nanR [H]

Synonym: Ddes_0854

Alternate gene names: 220904127

Gene position: 1001155-1001940 (Clockwise)

Preceding gene: 220904126

Following gene: 220904136

Centisome position: 34.84

GC content: 55.47

Gene sequence:

>786_bases
ATGACTACCGTAAATACGAACAACAGCAGCACTGAAAGGCTGCAAGGCAGACGGCGCAGCATACAGCGTCCGCGTGTGCA
TGTTGAGGTGCTGTCCTGTCTGTTGGAAGATATACAGTCCGGCGTATACCAGGTAGGGCAGAAACTGCCGTCCGAGCGCG
AGCTTATGGAAGAATTTGGTGTCGGCCGTCCGGCTGTGCGTGAGGCCTTGTCGGCGCTGGCGCGTATGGGACTTATAGAA
GTTTCGCCCGGTATGCGGGCGCGGGTTTGCAGGCTTACACTCAACCCGCTGTTGCGCGAAATGCGCGCCACTATGGAAAT
ATACTCGAGCACTCATGACGGCTGGAGGCAGATGCACGAACTGCGGCAGTTCTTCGAGACGGCCGTGGCCCGGCGTATGG
CGCGCCATATGACGGATGAACAGATGGTCGAGCTTGAGCGCATACTGCAAAAACAGCGCGGTTTGCTGGACGATTCGGCC
ATACGGGAATTTGCCGAGGCTGACATCGAGTTTCACCGTTACCTTGTGAACTGTGTCGGGAACAATTTTCTGGATATTGT
TTCCGACGGCTTTGCAGGCTGGTTGATTACTCCCCTGTACGCCTCCATGCAGGTACGGCAGCAGAGCGAACTGGCCTATG
AAGCTCATGTGCGCATTTTTGAAGCCCTGAAAAAGCGTGATGCCGATGCTGCGGAAGAAGCCATGCGGGCGCATCTGGAA
GAGATGCGCGGTATTTATCAGGTGGATGTCATGTCAGGCACGGAAAAAAAGCCGGGCAAGATGTAA

Upstream 100 bases:

>100_bases
GGCGTCAAATACACGCATGGATATTGTGTTGATACGTATATAATACCCCGGCAGAACTACCGGTCGGTTGCACTGCGATG
CAAGGAGATAATAGAATATC

Downstream 100 bases:

>100_bases
GGGCAGGCAAGCCGTAAGAAGCGTGTTTCCGGGGCCGCCGCCCTGTGCGTCGGGTTTGGGCATGCGCCCTGCTGGCCGCA
TGGCTGTCGGCCAGAAGGCG

Product: GntR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MTTVNTNNSSTERLQGRRRSIQRPRVHVEVLSCLLEDIQSGVYQVGQKLPSERELMEEFGVGRPAVREALSALARMGLIE
VSPGMRARVCRLTLNPLLREMRATMEIYSSTHDGWRQMHELRQFFETAVARRMARHMTDEQMVELERILQKQRGLLDDSA
IREFAEADIEFHRYLVNCVGNNFLDIVSDGFAGWLITPLYASMQVRQQSELAYEAHVRIFEALKKRDADAAEEAMRAHLE
EMRGIYQVDVMSGTEKKPGKM

Sequences:

>Translated_261_residues
MTTVNTNNSSTERLQGRRRSIQRPRVHVEVLSCLLEDIQSGVYQVGQKLPSERELMEEFGVGRPAVREALSALARMGLIE
VSPGMRARVCRLTLNPLLREMRATMEIYSSTHDGWRQMHELRQFFETAVARRMARHMTDEQMVELERILQKQRGLLDDSA
IREFAEADIEFHRYLVNCVGNNFLDIVSDGFAGWLITPLYASMQVRQQSELAYEAHVRIFEALKKRDADAAEEAMRAHLE
EMRGIYQVDVMSGTEKKPGKM
>Mature_260_residues
TTVNTNNSSTERLQGRRRSIQRPRVHVEVLSCLLEDIQSGVYQVGQKLPSERELMEEFGVGRPAVREALSALARMGLIEV
SPGMRARVCRLTLNPLLREMRATMEIYSSTHDGWRQMHELRQFFETAVARRMARHMTDEQMVELERILQKQRGLLDDSAI
REFAEADIEFHRYLVNCVGNNFLDIVSDGFAGWLITPLYASMQVRQQSELAYEAHVRIFEALKKRDADAAEEAMRAHLEE
MRGIYQVDVMSGTEKKPGKM

Specific function: Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789621, Length=214, Percent_Identity=34.5794392523364, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787821, Length=217, Percent_Identity=29.9539170506912, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789353, Length=213, Percent_Identity=27.2300469483568, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI87082208, Length=223, Percent_Identity=28.6995515695067, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 30031; Mature: 29900

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVNTNNSSTERLQGRRRSIQRPRVHVEVLSCLLEDIQSGVYQVGQKLPSERELMEEFG
CCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
VGRPAVREALSALARMGLIEVSPGMRARVCRLTLNPLLREMRATMEIYSSTHDGWRQMHE
CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LRQFFETAVARRMARHMTDEQMVELERILQKQRGLLDDSAIREFAEADIEFHRYLVNCVG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
NNFLDIVSDGFAGWLITPLYASMQVRQQSELAYEAHVRIFEALKKRDADAAEEAMRAHLE
CHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
EMRGIYQVDVMSGTEKKPGKM
HHCCCEEEHCCCCCCCCCCCC
>Mature Secondary Structure 
TTVNTNNSSTERLQGRRRSIQRPRVHVEVLSCLLEDIQSGVYQVGQKLPSERELMEEFG
CCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
VGRPAVREALSALARMGLIEVSPGMRARVCRLTLNPLLREMRATMEIYSSTHDGWRQMHE
CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LRQFFETAVARRMARHMTDEQMVELERILQKQRGLLDDSAIREFAEADIEFHRYLVNCVG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
NNFLDIVSDGFAGWLITPLYASMQVRQQSELAYEAHVRIFEALKKRDADAAEEAMRAHLE
CHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
EMRGIYQVDVMSGTEKKPGKM
HHCCCEEEHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA