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The map label for this gene is nadA [H]

Identifier: 220904081

GI number: 220904081

Start: 945706

End: 946752

Strand: Reverse

Name: nadA [H]

Synonym: Ddes_0807

Alternate gene names: 220904081

Gene position: 946752-945706 (Counterclockwise)

Preceding gene: 220904082

Following gene: 220904080

Centisome position: 32.95

GC content: 62.56

Gene sequence:

>1047_bases
ATGCAAGACATCAGTGCCGGTATTCAGGCTATCAAGCGCCAGCTTGGCGACAGGCTCTGCATTATGGGCCACCACTACCA
GAACGATGCCGTGGTGCAGCACTGCGACATCACGGGCGACTCGCTGGAACTGGCCCGCCGTGTGCCCCAGGTGAACGCGG
ACCATATCGTTTTTTGTGGCGTCTACTTTATGGGCGAATCCGCGGCGCTGCTGGCCAAGCCGGGCCAGGCAGTCTACCTG
CCGAGCATGGACGCGGACTGCCTCATGTCGCGGATGACCCCCGCCCCACTGGCCCGCAAGGTGCTGGAGCAGCTTTACGC
CCTTGGCCGCAAGGTCATTCCCCTAGCTTACGTCAATACTGATCTGGCCCTCAAGGCCGTGGTGGGTGAATACGGCGGCG
CCGTGTGTACATCAGCCAATGCGGGCATCATGCTGCAATGGGCCATGAAGCAGGGGGACGGCGTGCTGTTTTTGCCCGAC
ATGCACCTGGGCAACAATACGGCAACGGCCCTGGGTATCGCCCCACACGAAAGGCACGTGCTGCGCATAGGCTCCAGGGG
ACTGGTGGAGCCGGAAGCCCAGGCCCTGGACAGAAAGCTGCTGCTCTGGCCGGGCTGCTGCGCCATCCACGCCCGGTTTG
ACCCTGACGATGTACGTGAAATGCGCGCCGCGCACCCGGGCTGCCGCGTCATTGCTCACCCCGAATGCCGCGAGGATGTC
ATCGCAGTCTGCGACGGCGCCGGTTCCACATCCTACCTGATCAAAGACGCGGCTCGCGTGGCCGCTGAAGCCCCTGGCTC
CACGCTCATCGTGGGAACCGAGAACAATCTTGTCCACCGCCTTGCTGCCCGCCATGCGGGCCAATGCCGCATAATCCCCC
TGGGACACGCCATTTGCGGCAACATGGCCAAAGTGACGGAAAAAAAGCTCTGGACCATTCTCGAGGCAATTACCGCTCAA
AAAGCCACCCCTCTGGCGATCGAGGAGGAACTCTGCCCCCCCGCCCGCCTCTCGCTAACCCGCATGCTTGAAGTATGCGG
CCAATGA

Upstream 100 bases:

>100_bases
GGACGGCTAACCCATTCCGCCGTGGCGGCGGACTTCAGCATGACCCTGCTGCCGGCCTGATGCCGCGCGGGGCTGCCACT
TTCAGCACAGGGACAAGACA

Downstream 100 bases:

>100_bases
GGTTTGTGCCGTGAATGTCAGTCGCCGTCATGTGCCCGTATTAATTATTGGTTCGGGCATTGCCGGATGCACCGCCGCCC
TTACGCTGGCCGATGCCGGT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MQDISAGIQAIKRQLGDRLCIMGHHYQNDAVVQHCDITGDSLELARRVPQVNADHIVFCGVYFMGESAALLAKPGQAVYL
PSMDADCLMSRMTPAPLARKVLEQLYALGRKVIPLAYVNTDLALKAVVGEYGGAVCTSANAGIMLQWAMKQGDGVLFLPD
MHLGNNTATALGIAPHERHVLRIGSRGLVEPEAQALDRKLLLWPGCCAIHARFDPDDVREMRAAHPGCRVIAHPECREDV
IAVCDGAGSTSYLIKDAARVAAEAPGSTLIVGTENNLVHRLAARHAGQCRIIPLGHAICGNMAKVTEKKLWTILEAITAQ
KATPLAIEEELCPPARLSLTRMLEVCGQ

Sequences:

>Translated_348_residues
MQDISAGIQAIKRQLGDRLCIMGHHYQNDAVVQHCDITGDSLELARRVPQVNADHIVFCGVYFMGESAALLAKPGQAVYL
PSMDADCLMSRMTPAPLARKVLEQLYALGRKVIPLAYVNTDLALKAVVGEYGGAVCTSANAGIMLQWAMKQGDGVLFLPD
MHLGNNTATALGIAPHERHVLRIGSRGLVEPEAQALDRKLLLWPGCCAIHARFDPDDVREMRAAHPGCRVIAHPECREDV
IAVCDGAGSTSYLIKDAARVAAEAPGSTLIVGTENNLVHRLAARHAGQCRIIPLGHAICGNMAKVTEKKLWTILEAITAQ
KATPLAIEEELCPPARLSLTRMLEVCGQ
>Mature_348_residues
MQDISAGIQAIKRQLGDRLCIMGHHYQNDAVVQHCDITGDSLELARRVPQVNADHIVFCGVYFMGESAALLAKPGQAVYL
PSMDADCLMSRMTPAPLARKVLEQLYALGRKVIPLAYVNTDLALKAVVGEYGGAVCTSANAGIMLQWAMKQGDGVLFLPD
MHLGNNTATALGIAPHERHVLRIGSRGLVEPEAQALDRKLLLWPGCCAIHARFDPDDVREMRAAHPGCRVIAHPECREDV
IAVCDGAGSTSYLIKDAARVAAEAPGSTLIVGTENNLVHRLAARHAGQCRIIPLGHAICGNMAKVTEKKLWTILEAITAQ
KATPLAIEEELCPPARLSLTRMLEVCGQ

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 3 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 37514; Mature: 37514

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDISAGIQAIKRQLGDRLCIMGHHYQNDAVVQHCDITGDSLELARRVPQVNADHIVFCG
CCHHHHHHHHHHHHHCCEEEEECCEECCCCEEEEECCCCCHHHHHHHCCCCCCCEEEEEE
VYFMGESAALLAKPGQAVYLPSMDADCLMSRMTPAPLARKVLEQLYALGRKVIPLAYVNT
EEEECCCEEEEECCCCEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEECC
DLALKAVVGEYGGAVCTSANAGIMLQWAMKQGDGVLFLPDMHLGNNTATALGIAPHERHV
CHHHHHHHHHCCCEEEECCCCCEEEEEEEECCCCEEEECCCCCCCCCCEEEECCCCCCEE
LRIGSRGLVEPEAQALDRKLLLWPGCCAIHARFDPDDVREMRAAHPGCRVIAHPECREDV
EEECCCCCCCCHHHHHCCEEEEECCEEEEEECCCHHHHHHHHHCCCCCEEEECCCHHHHH
IAVCDGAGSTSYLIKDAARVAAEAPGSTLIVGTENNLVHRLAARHAGQCRIIPLGHAICG
HEEECCCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCEEEEECCHHHHC
NMAKVTEKKLWTILEAITAQKATPLAIEEELCPPARLSLTRMLEVCGQ
CHHHHHHHHHHHHHHHHHHCCCCCCEEHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MQDISAGIQAIKRQLGDRLCIMGHHYQNDAVVQHCDITGDSLELARRVPQVNADHIVFCG
CCHHHHHHHHHHHHHCCEEEEECCEECCCCEEEEECCCCCHHHHHHHCCCCCCCEEEEEE
VYFMGESAALLAKPGQAVYLPSMDADCLMSRMTPAPLARKVLEQLYALGRKVIPLAYVNT
EEEECCCEEEEECCCCEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEECC
DLALKAVVGEYGGAVCTSANAGIMLQWAMKQGDGVLFLPDMHLGNNTATALGIAPHERHV
CHHHHHHHHHCCCEEEECCCCCEEEEEEEECCCCEEEECCCCCCCCCCEEEECCCCCCEE
LRIGSRGLVEPEAQALDRKLLLWPGCCAIHARFDPDDVREMRAAHPGCRVIAHPECREDV
EEECCCCCCCCHHHHHCCEEEEECCEEEEEECCCHHHHHHHHHCCCCCEEEECCCHHHHH
IAVCDGAGSTSYLIKDAARVAAEAPGSTLIVGTENNLVHRLAARHAGQCRIIPLGHAICG
HEEECCCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCEEEEECCHHHHC
NMAKVTEKKLWTILEAITAQKATPLAIEEELCPPARLSLTRMLEVCGQ
CHHHHHHHHHHHHHHHHHHCCCCCCEEHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]