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The map label for this gene is hupE [H]

Identifier: 220904074

GI number: 220904074

Start: 936653

End: 937657

Strand: Reverse

Name: hupE [H]

Synonym: Ddes_0800

Alternate gene names: 220904074

Gene position: 937657-936653 (Counterclockwise)

Preceding gene: 220904075

Following gene: 220904069

Centisome position: 32.63

GC content: 61.79

Gene sequence:

>1005_bases
ATGGAAGACTGTCTTCTTCTGGATGCTGGCAGCGGTGGCAGGGCCTCACAGCGCCTGGTGGCCCAGTGCTTTTTTCGCCA
TTTTGCCAATCCCCTGCTGGAGCGCATGGATGACGCGGCCCTGCTGACGGATGTGCGCGGTCCTCTGGCCATGAGCACAG
ATTCCTACACAGTGACGCCCCTGATCTTTCCCGGCGGCAGCATCGGCAGCCTAGCCGTGCACGGCACGGTCAATGACGTA
GCCATGCTCGGCGCGCGCCCCCGCTACCTGAGTTGCGCCTTCATACTTGAAGAGGGCCTGTCCCTTGAAACGCTGGAACG
CGTCACTGCCGATATGGCCGCCGCCGCCCGCGAAGCCGGGGTGCTCATCGTTACCGGAGACACCAAGGTGGTTCCGCACG
GAGCGTGTGATAAAATATTCATCAATACCACCGGTATCGGCGAAGTTTTTGCTGATCCCGTGCCCTCCGGGCATAATGCC
CGCCCCGGCGATGCCGTGCTGGTAAGCGGAGCCATGGGCGACCACGGCCTGACGGTTATGGGCAGCCGCGAAGGACTCTC
CTTTCTGACGGACGTGGCCTCGGACTCTGCCCCGCTCAACCATATGGTCGTCGATATTCTTGAAAGCGCCGGGCCGGTGC
ATGTGCTGCGTGACCCCACCCGCGGGGGGCTGGCTACAACACTCAATGAAATTGCCGAGCAGTCACAGGTAGGCATTGTG
CTGGAAGAAAGCGCCATTCCCGTACATGAAGCGGTAAAGAACGGCTGTTCTTTCCTGGGGCTGGACCCCCTGTACCTTGC
CAATGAGGGCAAGTGCATCTGCATTGTGCCTGAAGACAGAGCCGAAGCAGCCCTTAAGGCCATGCGCCGCTCGCCCTACG
GCAAGGAAGCGGCGCGTGTGGGTACGGTTACTGACGGCAAGGCGCAGGTAAGCCTGCAAACACGCATCGGCGGCCGCCGG
CTGCTGGGTATGCTGGAAGGCGCGCAGTTGCCGCGCATCTGTTAG

Upstream 100 bases:

>100_bases
CGCTCTTCGGTAAAAAATGCACGCCCGCCACGCCGGTGGGACCATGCATGGTGTCCACCGAGGGCAGTTGTGCCGCCTAC
TTCAAATATTCGGAGCGATA

Downstream 100 bases:

>100_bases
AATAGTGTTTGATTGAAAAGTATTGTGAGAGAGGAAGAGAAGGCTTTGGTGGGGGAAGGGGAATTTTTTTGAAAAAAATT
CCCCTTCCCCCACCAAAGCC

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MEDCLLLDAGSGGRASQRLVAQCFFRHFANPLLERMDDAALLTDVRGPLAMSTDSYTVTPLIFPGGSIGSLAVHGTVNDV
AMLGARPRYLSCAFILEEGLSLETLERVTADMAAAAREAGVLIVTGDTKVVPHGACDKIFINTTGIGEVFADPVPSGHNA
RPGDAVLVSGAMGDHGLTVMGSREGLSFLTDVASDSAPLNHMVVDILESAGPVHVLRDPTRGGLATTLNEIAEQSQVGIV
LEESAIPVHEAVKNGCSFLGLDPLYLANEGKCICIVPEDRAEAALKAMRRSPYGKEAARVGTVTDGKAQVSLQTRIGGRR
LLGMLEGAQLPRIC

Sequences:

>Translated_334_residues
MEDCLLLDAGSGGRASQRLVAQCFFRHFANPLLERMDDAALLTDVRGPLAMSTDSYTVTPLIFPGGSIGSLAVHGTVNDV
AMLGARPRYLSCAFILEEGLSLETLERVTADMAAAAREAGVLIVTGDTKVVPHGACDKIFINTTGIGEVFADPVPSGHNA
RPGDAVLVSGAMGDHGLTVMGSREGLSFLTDVASDSAPLNHMVVDILESAGPVHVLRDPTRGGLATTLNEIAEQSQVGIV
LEESAIPVHEAVKNGCSFLGLDPLYLANEGKCICIVPEDRAEAALKAMRRSPYGKEAARVGTVTDGKAQVSLQTRIGGRR
LLGMLEGAQLPRIC
>Mature_334_residues
MEDCLLLDAGSGGRASQRLVAQCFFRHFANPLLERMDDAALLTDVRGPLAMSTDSYTVTPLIFPGGSIGSLAVHGTVNDV
AMLGARPRYLSCAFILEEGLSLETLERVTADMAAAAREAGVLIVTGDTKVVPHGACDKIFINTTGIGEVFADPVPSGHNA
RPGDAVLVSGAMGDHGLTVMGSREGLSFLTDVASDSAPLNHMVVDILESAGPVHVLRDPTRGGLATTLNEIAEQSQVGIV
LEESAIPVHEAVKNGCSFLGLDPLYLANEGKCICIVPEDRAEAALKAMRRSPYGKEAARVGTVTDGKAQVSLQTRIGGRR
LLGMLEGAQLPRIC

Specific function: May be involved in the maturation of the nifE hydrogenase [H]

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=330, Percent_Identity=47.2727272727273, Blast_Score=269, Evalue=2e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 35042; Mature: 35042

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDCLLLDAGSGGRASQRLVAQCFFRHFANPLLERMDDAALLTDVRGPLAMSTDSYTVTP
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEECCCCEEEEE
LIFPGGSIGSLAVHGTVNDVAMLGARPRYLSCAFILEEGLSLETLERVTADMAAAAREAG
EEECCCCCCCEEEECCHHHHHHHCCCCCCEEHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
VLIVTGDTKVVPHGACDKIFINTTGIGEVFADPVPSGHNARPGDAVLVSGAMGDHGLTVM
EEEEECCCEECCCCCCCEEEEECCCCCHHHCCCCCCCCCCCCCCEEEEECCCCCCCEEEE
GSREGLSFLTDVASDSAPLNHMVVDILESAGPVHVLRDPTRGGLATTLNEIAEQSQVGIV
ECCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCEE
LEESAIPVHEAVKNGCSFLGLDPLYLANEGKCICIVPEDRAEAALKAMRRSPYGKEAARV
EECCCCCHHHHHHCCCCEECCCCEEEECCCCEEEEECCHHHHHHHHHHHCCCCCCHHHEE
GTVTDGKAQVSLQTRIGGRRLLGMLEGAQLPRIC
CCCCCCCEEEEEEECCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MEDCLLLDAGSGGRASQRLVAQCFFRHFANPLLERMDDAALLTDVRGPLAMSTDSYTVTP
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEECCCCEEEEE
LIFPGGSIGSLAVHGTVNDVAMLGARPRYLSCAFILEEGLSLETLERVTADMAAAAREAG
EEECCCCCCCEEEECCHHHHHHHCCCCCCEEHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
VLIVTGDTKVVPHGACDKIFINTTGIGEVFADPVPSGHNARPGDAVLVSGAMGDHGLTVM
EEEEECCCEECCCCCCCEEEEECCCCCHHHCCCCCCCCCCCCCCEEEEECCCCCCCEEEE
GSREGLSFLTDVASDSAPLNHMVVDILESAGPVHVLRDPTRGGLATTLNEIAEQSQVGIV
ECCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCEE
LEESAIPVHEAVKNGCSFLGLDPLYLANEGKCICIVPEDRAEAALKAMRRSPYGKEAARV
EECCCCCHHHHHHCCCCEECCCCEEEECCCCEEEEECCHHHHHHHHHHHCCCCCCHHHEE
GTVTDGKAQVSLQTRIGGRRLLGMLEGAQLPRIC
CCCCCCCEEEEEEECCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1526470 [H]