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The map label for this gene is glpX [H]

Identifier: 220904027

GI number: 220904027

Start: 888416

End: 889399

Strand: Direct

Name: glpX [H]

Synonym: Ddes_0753

Alternate gene names: 220904027

Gene position: 888416-889399 (Clockwise)

Preceding gene: 220904026

Following gene: 220904028

Centisome position: 30.92

GC content: 60.47

Gene sequence:

>984_bases
ATGGTGGAAGCACCGGAGAAAAATCTGGCCCTGGACATTGTGCGTATTACCGAGGCGGCGGCCCTGGCATCGGCCCGCTG
GCTCGGGCGCGGAGACAAGGAGGCCGGAGACGGCGCTGCCGTGGACGCCATGCGCATCAGTTTTGCCACTCTGCACATTG
ACGGTCTTGTCATTATCGGCGAGGGCGAAAAAGATAATGCCCCCATGCTGTACAACGGCGAAAAGGTCGGCATGGGCGTG
GGACCCAGCCTTGATGTGGCCGTTGACCCGGTGGAAGGCACGAGCCTGCTGGCTTACGGGCGTCCCAACGCCATTTCCGT
CGTGGGCGTGGCCCCCAAGGGCAGCATGTTCAATCCTGGCCCCAGCTACTACATGCAAAAGCTCGTTGTGGCGCGCGAGG
CGCGCAACGTCATTGATCTTGACGCTCCCGTCAAGGTCAACCTGGCCAACGTGGCAAAAGCTATGGGCAAGAGCGTACAG
GATCTTGTGGTTTTTGTGCTGGACAAGCCCCGGCATGAAAAGCTCATTGCCGAAATCCGCGAAGCCGGAGCGCGCATACA
GCTGCAGACGGACGGCGACGTGGCCGGAGCGCTCATGGCTGTGGACCCCCGGTCCGAAGTGGACATCATGATGGGTACGG
GCGGCACTCCTGAAGGTGTGCTGGCGGCCTGCGCCATCAAGGGCATGGGCGGGCAGATGCTGGCCCGGCTCGACCCCCAG
TCCTATGTGGAAAAAGAGGCCATCAACGAGACGGGCATTGACGCACGCGAAGTGCTCACCGTTAACGATCTGGTGCGCAG
CGACGACTGTTTTTTTGCCGCCACGGGCATTTCCGGCGGCGATTTTCTGCGCGGCGTCGGCTACAGCGCCAAATACGCCG
TAACACATTCCCTGGTTTTGCGCGGCAAGACAGGAACGTTGCGGTATGTCGAGTCTTACCATAATATGGACAGACTCTCG
AAATTCAGCGCGGTACGGTATTGA

Upstream 100 bases:

>100_bases
GGAGCTTCGGGCGGCAGACCCGGGGGTTTTTTCTTGAAGCCGGCAGCGCGCTGGGGTAAGAGCAGTGTGTTGCATAACGC
AGATACGAGTGGAGGAAGAC

Downstream 100 bases:

>100_bases
ATGAATATTTTGTTGCGGATTTTCAGGATGTTCACAGGCCCTTCGGCCTTGCCATACATAAAAAATCCCGCACATACAGG
CAACTTGGCCTTGCGCGCGG

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MVEAPEKNLALDIVRITEAAALASARWLGRGDKEAGDGAAVDAMRISFATLHIDGLVIIGEGEKDNAPMLYNGEKVGMGV
GPSLDVAVDPVEGTSLLAYGRPNAISVVGVAPKGSMFNPGPSYYMQKLVVAREARNVIDLDAPVKVNLANVAKAMGKSVQ
DLVVFVLDKPRHEKLIAEIREAGARIQLQTDGDVAGALMAVDPRSEVDIMMGTGGTPEGVLAACAIKGMGGQMLARLDPQ
SYVEKEAINETGIDAREVLTVNDLVRSDDCFFAATGISGGDFLRGVGYSAKYAVTHSLVLRGKTGTLRYVESYHNMDRLS
KFSAVRY

Sequences:

>Translated_327_residues
MVEAPEKNLALDIVRITEAAALASARWLGRGDKEAGDGAAVDAMRISFATLHIDGLVIIGEGEKDNAPMLYNGEKVGMGV
GPSLDVAVDPVEGTSLLAYGRPNAISVVGVAPKGSMFNPGPSYYMQKLVVAREARNVIDLDAPVKVNLANVAKAMGKSVQ
DLVVFVLDKPRHEKLIAEIREAGARIQLQTDGDVAGALMAVDPRSEVDIMMGTGGTPEGVLAACAIKGMGGQMLARLDPQ
SYVEKEAINETGIDAREVLTVNDLVRSDDCFFAATGISGGDFLRGVGYSAKYAVTHSLVLRGKTGTLRYVESYHNMDRLS
KFSAVRY
>Mature_327_residues
MVEAPEKNLALDIVRITEAAALASARWLGRGDKEAGDGAAVDAMRISFATLHIDGLVIIGEGEKDNAPMLYNGEKVGMGV
GPSLDVAVDPVEGTSLLAYGRPNAISVVGVAPKGSMFNPGPSYYMQKLVVAREARNVIDLDAPVKVNLANVAKAMGKSVQ
DLVVFVLDKPRHEKLIAEIREAGARIQLQTDGDVAGALMAVDPRSEVDIMMGTGGTPEGVLAACAIKGMGGQMLARLDPQ
SYVEKEAINETGIDAREVLTVNDLVRSDDCFFAATGISGGDFLRGVGYSAKYAVTHSLVLRGKTGTLRYVESYHNMDRLS
KFSAVRY

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Is essential for growth on gluconeogenic carbon sources. Also displays a low activity toward glucose 6- phosphate, and fructose 6-phosphate, glycerol 3-phosphate, ribulose 1,5-

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=325, Percent_Identity=46.7692307692308, Blast_Score=288, Evalue=3e-79,
Organism=Escherichia coli, GI1789298, Length=320, Percent_Identity=41.5625, Blast_Score=236, Evalue=1e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 34714; Mature: 34714

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEAPEKNLALDIVRITEAAALASARWLGRGDKEAGDGAAVDAMRISFATLHIDGLVIIG
CCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCEEHHEEEEEEEEEEEEEEEEE
EGEKDNAPMLYNGEKVGMGVGPSLDVAVDPVEGTSLLAYGRPNAISVVGVAPKGSMFNPG
CCCCCCCCEEECCCEECCCCCCCCCEEECCCCCCEEEEECCCCEEEEEEECCCCCCCCCC
PSYYMQKLVVAREARNVIDLDAPVKVNLANVAKAMGKSVQDLVVFVLDKPRHEKLIAEIR
HHHHHHHHHHHHHHCCEEECCCCCEEEHHHHHHHHCCCHHHEEEEEECCCHHHHHHHHHH
EAGARIQLQTDGDVAGALMAVDPRSEVDIMMGTGGTPEGVLAACAIKGMGGQMLARLDPQ
HCCCEEEEEECCCCEEEEEEECCCCCEEEEEECCCCCHHHHEEHHHCCCCCHHEEECCHH
SYVEKEAINETGIDAREVLTVNDLVRSDDCFFAATGISGGDFLRGVGYSAKYAVTHSLVL
HHHHHHHHCCCCCCHHHEEEHHHHHCCCCCEEEEECCCCCHHHHCCCCCEEEEEEEEEEE
RGKTGTLRYVESYHNMDRLSKFSAVRY
ECCCCCHHHHHHHHCHHHHHHHHHCCC
>Mature Secondary Structure
MVEAPEKNLALDIVRITEAAALASARWLGRGDKEAGDGAAVDAMRISFATLHIDGLVIIG
CCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCEEHHEEEEEEEEEEEEEEEEE
EGEKDNAPMLYNGEKVGMGVGPSLDVAVDPVEGTSLLAYGRPNAISVVGVAPKGSMFNPG
CCCCCCCCEEECCCEECCCCCCCCCEEECCCCCCEEEEECCCCEEEEEEECCCCCCCCCC
PSYYMQKLVVAREARNVIDLDAPVKVNLANVAKAMGKSVQDLVVFVLDKPRHEKLIAEIR
HHHHHHHHHHHHHHCCEEECCCCCEEEHHHHHHHHCCCHHHEEEEEECCCHHHHHHHHHH
EAGARIQLQTDGDVAGALMAVDPRSEVDIMMGTGGTPEGVLAACAIKGMGGQMLARLDPQ
HCCCEEEEEECCCCEEEEEEECCCCCEEEEEECCCCCHHHHEEHHHCCCCCHHEEECCHH
SYVEKEAINETGIDAREVLTVNDLVRSDDCFFAATGISGGDFLRGVGYSAKYAVTHSLVL
HHHHHHHHCCCCCCHHHEEEHHHHHCCCCCEEEEECCCCCHHHHCCCCCEEEEEEEEEEE
RGKTGTLRYVESYHNMDRLSKFSAVRY
ECCCCCHHHHHHHHCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]