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The map label for this gene is fabD [H]

Identifier: 220904018

GI number: 220904018

Start: 877473

End: 878414

Strand: Reverse

Name: fabD [H]

Synonym: Ddes_0744

Alternate gene names: 220904018

Gene position: 878414-877473 (Counterclockwise)

Preceding gene: 220904021

Following gene: 220904017

Centisome position: 30.57

GC content: 62.85

Gene sequence:

>942_bases
ATGTCACAAGCCGTTTTGCTCTTTCCCGGTCAGGGTTCACAGGAAGCAGGTATGGGCCGCGATCTGGCCGAGGCCTCCAC
AGAGGCCATGAACCTCTGGAAACAGGCCGAGCGTGCAAGCTCCCTGCCCCTGCGCGAAATATACTGGGAGGGCGATGATG
CCGCCATGAGCGACACCCGCGCCCTGCAACCGGCCCTGACCGTGGTAAACCTGAACCTCTGGAACGCTGTGGCGAATCGC
GTGAAGCCTCTGGGCGCCGCCGGACACAGCCTTGGAGAATTCAGCGCCATGGCTGCGGCGGGCGTTCTTTCTCCCCAGGC
CGTACTGGAACTGACCAGCCTGCGCGGCCGCCTGATGGCCGAAGCCGATCCTGACGGCAAGGGGGCCATGGCCGCCCTGC
TCAAGCTTGACCTGCCCCAGGTGGAAAAAATTGTGGCCGATACGGCGGCCCAGTGCGGCGAGCTGATTATTGTAGCCAAC
TACAACACTCCCGCCCAGCTCGTAGTCAGCGGCACCAAAGCCGCTGTGGCCCTGGCCTGCCAGAAAGCCAAGGAAATGAA
AGGCCGCGGCATTGAGCTTAAGGTCAGCGGTGCTTTCCACAGCCCCCTCATGGCCGAAGCCTCCAAAGAATTCGCCCCGC
AACTGCGCAAGGCCACCTGGAACAAGCCCCGCTTTGCTGTCTACTGCAACGCCCACGGCAGGGCCGTTCATGAAGGCGAA
AGCGCCCTTGAGGGCCTGATGGCACAGATGACCTCGTCAGTGCAATGGATCGACACCATGCGCAATCAGTATGACAACGG
CGCGCGCCGCTGGCTTGAGCTTGGTCCCAAGGCCCTGCTCGGCAAGATGGTGCCCCCCTGCCTTACCGACCGCGCCGCTG
CGGACCAGCTTGACATACAGCTGGTCAACAATGCGGAACGTGCCGCAGCCCTGGCGGAATAG

Upstream 100 bases:

>100_bases
GCCCCGCGCCGATAACGTAAAAAAGAGGGCTTGCGGACGTGCTGCGTATATCTTGACCATTTTTGCGGCGTCCGCCATTC
TTTCCGGAGGATACATTCCA

Downstream 100 bases:

>100_bases
CAGACCGGACCGCCCGACAGCCCCTGCGCGGTCTTCCGTAGTTACCGGATTTCTGGATTTTTCAAAAATACACTGTTATG
AGCCGAATCCCCGGATACAC

Product: acyl transferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSQAVLLFPGQGSQEAGMGRDLAEASTEAMNLWKQAERASSLPLREIYWEGDDAAMSDTRALQPALTVVNLNLWNAVANR
VKPLGAAGHSLGEFSAMAAAGVLSPQAVLELTSLRGRLMAEADPDGKGAMAALLKLDLPQVEKIVADTAAQCGELIIVAN
YNTPAQLVVSGTKAAVALACQKAKEMKGRGIELKVSGAFHSPLMAEASKEFAPQLRKATWNKPRFAVYCNAHGRAVHEGE
SALEGLMAQMTSSVQWIDTMRNQYDNGARRWLELGPKALLGKMVPPCLTDRAAADQLDIQLVNNAERAAALAE

Sequences:

>Translated_313_residues
MSQAVLLFPGQGSQEAGMGRDLAEASTEAMNLWKQAERASSLPLREIYWEGDDAAMSDTRALQPALTVVNLNLWNAVANR
VKPLGAAGHSLGEFSAMAAAGVLSPQAVLELTSLRGRLMAEADPDGKGAMAALLKLDLPQVEKIVADTAAQCGELIIVAN
YNTPAQLVVSGTKAAVALACQKAKEMKGRGIELKVSGAFHSPLMAEASKEFAPQLRKATWNKPRFAVYCNAHGRAVHEGE
SALEGLMAQMTSSVQWIDTMRNQYDNGARRWLELGPKALLGKMVPPCLTDRAAADQLDIQLVNNAERAAALAE
>Mature_312_residues
SQAVLLFPGQGSQEAGMGRDLAEASTEAMNLWKQAERASSLPLREIYWEGDDAAMSDTRALQPALTVVNLNLWNAVANRV
KPLGAAGHSLGEFSAMAAAGVLSPQAVLELTSLRGRLMAEADPDGKGAMAALLKLDLPQVEKIVADTAAQCGELIIVANY
NTPAQLVVSGTKAAVALACQKAKEMKGRGIELKVSGAFHSPLMAEASKEFAPQLRKATWNKPRFAVYCNAHGRAVHEGES
ALEGLMAQMTSSVQWIDTMRNQYDNGARRWLELGPKALLGKMVPPCLTDRAAADQLDIQLVNNAERAAALAE

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=303, Percent_Identity=30.6930693069307, Blast_Score=106, Evalue=3e-23,
Organism=Escherichia coli, GI1787334, Length=284, Percent_Identity=32.0422535211268, Blast_Score=133, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71984332, Length=289, Percent_Identity=24.2214532871972, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17550940, Length=294, Percent_Identity=26.1904761904762, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24665753, Length=289, Percent_Identity=31.1418685121107, Blast_Score=102, Evalue=4e-22,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33390; Mature: 33258

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQAVLLFPGQGSQEAGMGRDLAEASTEAMNLWKQAERASSLPLREIYWEGDDAAMSDTR
CCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCHHHHHH
ALQPALTVVNLNLWNAVANRVKPLGAAGHSLGEFSAMAAAGVLSPQAVLELTSLRGRLMA
HHCHHHEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCEEE
EADPDGKGAMAALLKLDLPQVEKIVADTAAQCGELIIVANYNTPAQLVVSGTKAAVALAC
CCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCHHHHHHHH
QKAKEMKGRGIELKVSGAFHSPLMAEASKEFAPQLRKATWNKPRFAVYCNAHGRAVHEGE
HHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEHHHH
SALEGLMAQMTSSVQWIDTMRNQYDNGARRWLELGPKALLGKMVPPCLTDRAAADQLDIQ
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCHHHHHHHCCCCHHCCCCCCCHHHEE
LVNNAERAAALAE
EECCHHHHHHCCC
>Mature Secondary Structure 
SQAVLLFPGQGSQEAGMGRDLAEASTEAMNLWKQAERASSLPLREIYWEGDDAAMSDTR
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCHHHHHH
ALQPALTVVNLNLWNAVANRVKPLGAAGHSLGEFSAMAAAGVLSPQAVLELTSLRGRLMA
HHCHHHEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCEEE
EADPDGKGAMAALLKLDLPQVEKIVADTAAQCGELIIVANYNTPAQLVVSGTKAAVALAC
CCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCHHHHHHHH
QKAKEMKGRGIELKVSGAFHSPLMAEASKEFAPQLRKATWNKPRFAVYCNAHGRAVHEGE
HHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEHHHH
SALEGLMAQMTSSVQWIDTMRNQYDNGARRWLELGPKALLGKMVPPCLTDRAAADQLDIQ
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCHHHHHHHCCCCHHCCCCCCCHHHEE
LVNNAERAAALAE
EECCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA