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The map label for this gene is argS

Identifier: 220904017

GI number: 220904017

Start: 875664

End: 877316

Strand: Reverse

Name: argS

Synonym: Ddes_0743

Alternate gene names: 220904017

Gene position: 877316-875664 (Counterclockwise)

Preceding gene: 220904018

Following gene: 220904016

Centisome position: 30.53

GC content: 62.37

Gene sequence:

>1653_bases
ATGCGCGCCATTGAAACCCTGCGCACGGCCCTGGCGGCCATTATTGAGGAAGAGGGCCTGGCCTGGCCCTCCAAGACTGT
CATTGAGCCGCCGCGCGATCCCCGCCACGGCGATCTTTCGGTTAATTCGGCCATGCTGCTCGCCAGGGAAGCCAAGACCA
ATCCCCGTGAGCTGGCGCAAAAATTTGCCGCCAGGCTTCTGGAGCGCTGCCCCGATGTGGAAAAAGCCGAGGCTGCCGGG
CCGGGTTTCTGCAACGTGACATTCAGCCAGGCCTTCTGGCGGCAGACCGTCACCGACATTGAAAGCGCGGGACAGGCCTA
TGGCGAAAGCCGTGAGCCGGGCCGCAGGGTGCTGCTTGAATATGTTTCGGCCAATCCCACGGGGCCGCTGCATGTGGGAC
ACGGGCGCGGCGCTGCCGTGGGTGACAGCCTCGCCCGCCTGCTGCGCAAGGCCGGGCATCATGTGCATACCGAGTACTAT
ATCAACGACGCGGGCCGCCAGATGCGCCTGCTGGGCCTTTCCGTGTGGCTGCGCGTGCTGGAGCTGGCCGGACGCCCCGT
AGAATGGCCCGAAGACTACTACAGGGGCGATTACATCATAGACATCGCCCGCGAAATGCTCACGGCCAATCCCGCCCTGC
CGGACATGCCCGCCCCCGAAGGCGAAGACCTGTGTTACGAAAAGGCCATGACCGACATTCTCAACGGCATCAAGGACGAC
CTGCGCGACTTTCGCGTGGAGCACCTGCGCTGGTTCTCGGAAAAAACCCTGGTGGAAACCGGGGCCGTGGACGCTGCCTT
TGCCGCGCTGGGCAAATCGGGCTACACCTACGAACAGGACAATGCCTTCTGGTTCGCCACCGAGCAGTTGGGCGACGACA
AAAACCGCGTACTCAAAAAATCCGACGGCAGCCTGACCTACTTCGCCTCCGACATTGCCTATCATCATGACAAGTTTGAA
CGCGGCTATGACTGGCTCATCGACGTGTGGGGCGCGGACCATCACGGCTATATCCCCCGCATGCGCGCGGCCATTACCGC
CATGGGCAAAGAGCGCGACAGCTTTGACGTGGTGCTCATCCAGCTTGTGAACCTGCTCCGCGAGGGGCAGCCCGTGAGCA
TGTCCACCCGCGCGGGAACCTTTGAAACCCTGGCGGATGTCATCAAGGAAGTGGGTACAGATGCCGCCCGCTTCATGTTT
CTTTCGCGCAAGAGCGACAGCCCGCTGGATTTCGACCTTGAACTTGCCAAGCAGCGCAGCCTGGACAACCCTGTTTACTA
CGTGCAATACGCTCATGCCCGCATCTGTGCAGTGCTGCGGCGCGCCGCCGAGCGCGGCTTCGTCCTGCCGGAAAAATCCG
ATGCAGCCCTGCTTGCCCCCCTGGATACGGCAGAGGACATGACCCTGCTGCGCAAGGCCGCCGCTTTTGAAGACATGCTT
TTTGCAGCGGCCCAATCCCTTGGCGTACACCACGTAAGCCACTATCTGACCGAACTGGCAGGGCTGCTGCACAGCTATTA
TGCCAGGCATCAGGTATTGCTGGCCGACGACGCGCCGCGCACCCTGGCCCGACTGGCCCTGCTGCGCTCTGTGGGACAGG
TGGTGCGCAACGGCCTGGACGTTCTCGGCGTAAGCGCACCCGAAAGCATGTAG

Upstream 100 bases:

>100_bases
ATTTTTCAAAAATACACTGTTATGAGCCGAATCCCCGGATACACACGGGCATCGGAATGCAGAGAACTGAAACCCTGTAT
GTAAAGGACACGAGAGCATT

Downstream 100 bases:

>100_bases
CAGCGATGCGGCCCCACAGGGTCGCTCGCCTGCAAGGCAGCCTTGCTGTGCAACGGACAGTAAAACTGCCCGGCTGATAC
CGAACCTTCGGCCATCACCG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 550; Mature: 550

Protein sequence:

>550_residues
MRAIETLRTALAAIIEEEGLAWPSKTVIEPPRDPRHGDLSVNSAMLLAREAKTNPRELAQKFAARLLERCPDVEKAEAAG
PGFCNVTFSQAFWRQTVTDIESAGQAYGESREPGRRVLLEYVSANPTGPLHVGHGRGAAVGDSLARLLRKAGHHVHTEYY
INDAGRQMRLLGLSVWLRVLELAGRPVEWPEDYYRGDYIIDIAREMLTANPALPDMPAPEGEDLCYEKAMTDILNGIKDD
LRDFRVEHLRWFSEKTLVETGAVDAAFAALGKSGYTYEQDNAFWFATEQLGDDKNRVLKKSDGSLTYFASDIAYHHDKFE
RGYDWLIDVWGADHHGYIPRMRAAITAMGKERDSFDVVLIQLVNLLREGQPVSMSTRAGTFETLADVIKEVGTDAARFMF
LSRKSDSPLDFDLELAKQRSLDNPVYYVQYAHARICAVLRRAAERGFVLPEKSDAALLAPLDTAEDMTLLRKAAAFEDML
FAAAQSLGVHHVSHYLTELAGLLHSYYARHQVLLADDAPRTLARLALLRSVGQVVRNGLDVLGVSAPESM

Sequences:

>Translated_550_residues
MRAIETLRTALAAIIEEEGLAWPSKTVIEPPRDPRHGDLSVNSAMLLAREAKTNPRELAQKFAARLLERCPDVEKAEAAG
PGFCNVTFSQAFWRQTVTDIESAGQAYGESREPGRRVLLEYVSANPTGPLHVGHGRGAAVGDSLARLLRKAGHHVHTEYY
INDAGRQMRLLGLSVWLRVLELAGRPVEWPEDYYRGDYIIDIAREMLTANPALPDMPAPEGEDLCYEKAMTDILNGIKDD
LRDFRVEHLRWFSEKTLVETGAVDAAFAALGKSGYTYEQDNAFWFATEQLGDDKNRVLKKSDGSLTYFASDIAYHHDKFE
RGYDWLIDVWGADHHGYIPRMRAAITAMGKERDSFDVVLIQLVNLLREGQPVSMSTRAGTFETLADVIKEVGTDAARFMF
LSRKSDSPLDFDLELAKQRSLDNPVYYVQYAHARICAVLRRAAERGFVLPEKSDAALLAPLDTAEDMTLLRKAAAFEDML
FAAAQSLGVHHVSHYLTELAGLLHSYYARHQVLLADDAPRTLARLALLRSVGQVVRNGLDVLGVSAPESM
>Mature_550_residues
MRAIETLRTALAAIIEEEGLAWPSKTVIEPPRDPRHGDLSVNSAMLLAREAKTNPRELAQKFAARLLERCPDVEKAEAAG
PGFCNVTFSQAFWRQTVTDIESAGQAYGESREPGRRVLLEYVSANPTGPLHVGHGRGAAVGDSLARLLRKAGHHVHTEYY
INDAGRQMRLLGLSVWLRVLELAGRPVEWPEDYYRGDYIIDIAREMLTANPALPDMPAPEGEDLCYEKAMTDILNGIKDD
LRDFRVEHLRWFSEKTLVETGAVDAAFAALGKSGYTYEQDNAFWFATEQLGDDKNRVLKKSDGSLTYFASDIAYHHDKFE
RGYDWLIDVWGADHHGYIPRMRAAITAMGKERDSFDVVLIQLVNLLREGQPVSMSTRAGTFETLADVIKEVGTDAARFMF
LSRKSDSPLDFDLELAKQRSLDNPVYYVQYAHARICAVLRRAAERGFVLPEKSDAALLAPLDTAEDMTLLRKAAAFEDML
FAAAQSLGVHHVSHYLTELAGLLHSYYARHQVLLADDAPRTLARLALLRSVGQVVRNGLDVLGVSAPESM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=602, Percent_Identity=24.7508305647841, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1788184, Length=587, Percent_Identity=24.5315161839864, Blast_Score=99, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71985061, Length=576, Percent_Identity=23.4375, Blast_Score=101, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI71985068, Length=536, Percent_Identity=23.6940298507463, Blast_Score=96, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6320548, Length=566, Percent_Identity=24.9116607773852, Blast_Score=108, Evalue=3e-24,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_DESDA (B8IYS4)

Other databases:

- EMBL:   CP001358
- RefSeq:   YP_002479329.1
- ProteinModelPortal:   B8IYS4
- GeneID:   7284417
- GenomeReviews:   CP001358_GR
- KEGG:   dds:Ddes_0743
- HOGENOM:   HBG695395
- ProtClustDB:   PRK01611
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 61287; Mature: 61287

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAIETLRTALAAIIEEEGLAWPSKTVIEPPRDPRHGDLSVNSAMLLAREAKTNPRELAQ
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHH
KFAARLLERCPDVEKAEAAGPGFCNVTFSQAFWRQTVTDIESAGQAYGESREPGRRVLLE
HHHHHHHHHCCCCCHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
YVSANPTGPLHVGHGRGAAVGDSLARLLRKAGHHVHTEYYINDAGRQMRLLGLSVWLRVL
HHHCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHH
ELAGRPVEWPEDYYRGDYIIDIAREMLTANPALPDMPAPEGEDLCYEKAMTDILNGIKDD
HHCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LRDFRVEHLRWFSEKTLVETGAVDAAFAALGKSGYTYEQDNAFWFATEQLGDDKNRVLKK
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEECCCEEEEEHHHHCCCHHHHHHC
SDGSLTYFASDIAYHHDKFERGYDWLIDVWGADHHGYIPRMRAAITAMGKERDSFDVVLI
CCCCEEEEHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHH
QLVNLLREGQPVSMSTRAGTFETLADVIKEVGTDAARFMFLSRKSDSPLDFDLELAKQRS
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHCC
LDNPVYYVQYAHARICAVLRRAAERGFVLPEKSDAALLAPLDTAEDMTLLRKAAAFEDML
CCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHH
FAAAQSLGVHHVSHYLTELAGLLHSYYARHQVLLADDAPRTLARLALLRSVGQVVRNGLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHHHHCCCC
VLGVSAPESM
EEECCCCCCC
>Mature Secondary Structure
MRAIETLRTALAAIIEEEGLAWPSKTVIEPPRDPRHGDLSVNSAMLLAREAKTNPRELAQ
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHH
KFAARLLERCPDVEKAEAAGPGFCNVTFSQAFWRQTVTDIESAGQAYGESREPGRRVLLE
HHHHHHHHHCCCCCHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
YVSANPTGPLHVGHGRGAAVGDSLARLLRKAGHHVHTEYYINDAGRQMRLLGLSVWLRVL
HHHCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHH
ELAGRPVEWPEDYYRGDYIIDIAREMLTANPALPDMPAPEGEDLCYEKAMTDILNGIKDD
HHCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LRDFRVEHLRWFSEKTLVETGAVDAAFAALGKSGYTYEQDNAFWFATEQLGDDKNRVLKK
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEECCCEEEEEHHHHCCCHHHHHHC
SDGSLTYFASDIAYHHDKFERGYDWLIDVWGADHHGYIPRMRAAITAMGKERDSFDVVLI
CCCCEEEEHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHH
QLVNLLREGQPVSMSTRAGTFETLADVIKEVGTDAARFMFLSRKSDSPLDFDLELAKQRS
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHCC
LDNPVYYVQYAHARICAVLRRAAERGFVLPEKSDAALLAPLDTAEDMTLLRKAAAFEDML
CCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHH
FAAAQSLGVHHVSHYLTELAGLLHSYYARHQVLLADDAPRTLARLALLRSVGQVVRNGLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHHHHCCCC
VLGVSAPESM
EEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA