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The map label for this gene is secY [H]

Identifier: 220903954

GI number: 220903954

Start: 810248

End: 811561

Strand: Direct

Name: secY [H]

Synonym: Ddes_0680

Alternate gene names: 220903954

Gene position: 810248-811561 (Clockwise)

Preceding gene: 220903953

Following gene: 220903955

Centisome position: 28.2

GC content: 55.02

Gene sequence:

>1314_bases
ATGGCAGTAGGAACGGCAAACACTGTGGCGGGTCAGCCTTCGCTGTTCAAGCGACTTGGCTGGACCTTCCTGATTTTGTG
CTGCTACCGTATTGGTGTGCATGTGCCCATTCCGGGTGTGGACGCCTCCGCCCTTGCTTCTTTTTTTCAAAGCATGCAGG
GGACGCTGTTCAGCCTTTTTGACATGTTCTCCGGCGGTGGCCTGTCCAACGTTTCCGTCTTTGCCCTGGGCGTCATGCCG
TATATTTCGGCCAGCATCATCATGCAGCTGCTCCAGGTCATCAGCCCGGACGTGAAGCGCATGGCAAAGGAAGAGGGGCA
GGCCGGGCGGCGCAAGCTCACCCAGTACACCCGCTACCTTACCGTGCTCATCACTCTGGTGCAGGGCCTGGGCATCGCCG
TAGGCCTTGAGAACATGACAAGCCCTGCAGGTACGCCCGTGGTGCTTAACCCGGGCTGGCAGTTCCGCATGGTGACCATG
ACCACGTTTACCGCCGGTTCGGTGCTGGTTATGTGGCTTGGCGAACAGATTACGGAACGCGGCATCGGTAACGGCATTTC
GCTGATCATTTTCTGCGGTATCGTTGTGGGCATCCCCCGTGGGATCATTCAGTCCGTGGCGCTTATACAGGCTGGGGACA
TGAGCATTTTCATGGCAGTGGTCATCGTGGTCTTCATGGCTGCAGTGCTTGTGGCCATTGTTTTTGTGGAACGGTCGCAG
CGGCGTATACCCATAAGTTATGCCAAGCGGCAGGTGGGCCGTAAAATGTACGGCGGGCAGAACTCGCATCTGCCCCTGCG
TCTCAATACGGCTGGCGTTATTCCGCCTATTTTCGCCTCTTCATTGCTGCTTTTTCCGGCCACCATCGGCCAGTTTTCCA
GCAATGAGTATGTAAAGCATGCGGCCGAGCTGTTCTCTCCCCAGGGCGTGGCTTACAACGTGCTTTATGTGGCCCTCATG
TTCTTCTTCTGTTACTTCTATACTGCCATCATCTTTGATCCCAAGGATATGGCTGAAAACCTCAAGAAGAACGGCGGCTT
TATCCCCGGCATACGTCCCGGCGAAAAGACACAGGAATATATTGATACTGTACTGACGCGGCTGACCCTTTCGGGGGCCA
CCTATATTTCCATCGTATGTCTGCTGCCCATGTTGCTCATCAGCAATTTTAACGTGCCGTTCTTCTTTGGTGGTACGAGC
TTGCTGATTCTTGTGGGCGTGGCTATGGACTTTATGAATCAGGTGGAATCGCATATGATTTCCAGCCAGTATCAGGGCCT
GATGGCCAAGGCGCGCAAAAGCGGCCGGCTGTAA

Upstream 100 bases:

>100_bases
CCCTGTCAATGCCTGGCATTGGCCTCATTGTCTTCGTGAGCGAAGGGAATGAGGCTGTGCATATACTGCGCCTGAGGCGC
ATAAACGCAAAGAGTCTTAC

Downstream 100 bases:

>100_bases
CCAACGGGTGATGGAGTATGAAGAAATATCACGGCGCGTACATCAAGAATGAGCGTGAAATCGGCTGCCTGCGCGAAGCT
AACCGCATGGTCGCCAACGT

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MAVGTANTVAGQPSLFKRLGWTFLILCCYRIGVHVPIPGVDASALASFFQSMQGTLFSLFDMFSGGGLSNVSVFALGVMP
YISASIIMQLLQVISPDVKRMAKEEGQAGRRKLTQYTRYLTVLITLVQGLGIAVGLENMTSPAGTPVVLNPGWQFRMVTM
TTFTAGSVLVMWLGEQITERGIGNGISLIIFCGIVVGIPRGIIQSVALIQAGDMSIFMAVVIVVFMAAVLVAIVFVERSQ
RRIPISYAKRQVGRKMYGGQNSHLPLRLNTAGVIPPIFASSLLLFPATIGQFSSNEYVKHAAELFSPQGVAYNVLYVALM
FFFCYFYTAIIFDPKDMAENLKKNGGFIPGIRPGEKTQEYIDTVLTRLTLSGATYISIVCLLPMLLISNFNVPFFFGGTS
LLILVGVAMDFMNQVESHMISSQYQGLMAKARKSGRL

Sequences:

>Translated_437_residues
MAVGTANTVAGQPSLFKRLGWTFLILCCYRIGVHVPIPGVDASALASFFQSMQGTLFSLFDMFSGGGLSNVSVFALGVMP
YISASIIMQLLQVISPDVKRMAKEEGQAGRRKLTQYTRYLTVLITLVQGLGIAVGLENMTSPAGTPVVLNPGWQFRMVTM
TTFTAGSVLVMWLGEQITERGIGNGISLIIFCGIVVGIPRGIIQSVALIQAGDMSIFMAVVIVVFMAAVLVAIVFVERSQ
RRIPISYAKRQVGRKMYGGQNSHLPLRLNTAGVIPPIFASSLLLFPATIGQFSSNEYVKHAAELFSPQGVAYNVLYVALM
FFFCYFYTAIIFDPKDMAENLKKNGGFIPGIRPGEKTQEYIDTVLTRLTLSGATYISIVCLLPMLLISNFNVPFFFGGTS
LLILVGVAMDFMNQVESHMISSQYQGLMAKARKSGRL
>Mature_436_residues
AVGTANTVAGQPSLFKRLGWTFLILCCYRIGVHVPIPGVDASALASFFQSMQGTLFSLFDMFSGGGLSNVSVFALGVMPY
ISASIIMQLLQVISPDVKRMAKEEGQAGRRKLTQYTRYLTVLITLVQGLGIAVGLENMTSPAGTPVVLNPGWQFRMVTMT
TFTAGSVLVMWLGEQITERGIGNGISLIIFCGIVVGIPRGIIQSVALIQAGDMSIFMAVVIVVFMAAVLVAIVFVERSQR
RIPISYAKRQVGRKMYGGQNSHLPLRLNTAGVIPPIFASSLLLFPATIGQFSSNEYVKHAAELFSPQGVAYNVLYVALMF
FFCYFYTAIIFDPKDMAENLKKNGGFIPGIRPGEKTQEYIDTVLTRLTLSGATYISIVCLLPMLLISNFNVPFFFGGTSL
LILVGVAMDFMNQVESHMISSQYQGLMAKARKSGRL

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=429, Percent_Identity=49.8834498834499, Blast_Score=400, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 47582; Mature: 47451

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AVGTANTVAGQPSLFKRLGWTFLILCCYRIGVHVPIPGVDASALASFFQSMQGTLFSLF
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DMFSGGGLSNVSVFALGVMPYISASIIMQLLQVISPDVKRMAKEEGQAGRRKLTQYTRYL
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCHHHHHHHHHHHHHH
TVLITLVQGLGIAVGLENMTSPAGTPVVLNPGWQFRMVTMTTFTAGSVLVMWLGEQITER
HHHHHHHHHHHHHEEHHHCCCCCCCCEEECCCCCEEEEEEEEECCHHHHHHHHHHHHHHC
GIGNGISLIIFCGIVVGIPRGIIQSVALIQAGDMSIFMAVVIVVFMAAVLVAIVFVERSQ
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
RRIPISYAKRQVGRKMYGGQNSHLPLRLNTAGVIPPIFASSLLLFPATIGQFSSNEYVKH
CCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHH
AAELFSPQGVAYNVLYVALMFFFCYFYTAIIFDPKDMAENLKKNGGFIPGIRPGEKTQEY
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHH
IDTVLTRLTLSGATYISIVCLLPMLLISNFNVPFFFGGTSLLILVGVAMDFMNQVESHMI
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHH
SSQYQGLMAKARKSGRL
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]