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The map label for this gene is cdsA [H]

Identifier: 220903794

GI number: 220903794

Start: 627914

End: 628732

Strand: Reverse

Name: cdsA [H]

Synonym: Ddes_0517

Alternate gene names: 220903794

Gene position: 628732-627914 (Counterclockwise)

Preceding gene: 220903795

Following gene: 220903793

Centisome position: 21.88

GC content: 59.46

Gene sequence:

>819_bases
ATGCCCATTGAACCCACCGCCAATCCCATCGACATCCGCCGCATCATAACCGGCGTATTGCTGGCCGCAGTGCTGTTGCT
GGTGCTCTGGCTGCGGGGCTGGCCCCTGCTGTTCGTCATTCTGCTGGTGTCGGCCCTGGGCCTGTGGGAATTCTATTCTC
TTTTCTGGGGTCCCAAGGGGCGCATCACCAGCCGTGTATGCGCCATCGGCCTGGGCTGGGGCATGCTTTGCCTCACCTGG
ATGAACCGCCCGCAGGACGCCCTGGTGTGCCTTGGCGCGGGCTTTGTCCTGTCGGCCATGAGCTTTCTCTTTCGCTGGGA
CGTTGTTGAAGAGGATAATGCCTTTGTGTCCAGCGGTATCTTCATGGCCGGGCTGGCCTATGTCCCCCTGCTGCTTCTGC
CGGCCACCTATCTTTCCACCACCAAACTCATCTTCGTCATCGCTGCCGTGGCCATTTCCGACACTGCCGCCTATTTTGTG
GGTACCCGCTTCGGGCATCACAAGCTCTGGCCCCGCGTCAGCCCCAAGAAAAGCTCCGAAGGCGCTGTAGGCAGCCTGGT
GGCCTGCGTAATCTTTTGCGCCATTTACGGCGAGCTTTACGGCAAAACAGGCTGGCTGTCCTTTGCTCTTCTGGGTATTG
CGGTCAACGCCTTTGCCCAGGTGGGCGATCTTTTTGAGTCGGCCCTCAAGCGTTCGGTCAATGTAAAAGATTCCGGGCAC
CTCCTGCCGGGACACGGCGGCGTGCTGGACAGGGCAGACAGCCTGCTCTTTGCCATGCCTATGGTGGCAGTTGTGGACCA
GTGGTTCTTTTTCTTTTAG

Upstream 100 bases:

>100_bases
CAGGTGGCCTGGCCAGATTTTGACGCCGCGCAACTGCGTCTGGCCCTGGAAGCTTACGCCGCGCGGTCGCGCCGCTTTGG
CAAAACACAGGAGCAAATAG

Downstream 100 bases:

>100_bases
AGCATGCCGGAAAGATACATTCGCAACATTTTTCCGGCGTTGACGCTAACGCTTGACCGCACACACAGCGCATGCGCCTT
TGCGGCGGATGCCTGCCCGT

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MPIEPTANPIDIRRIITGVLLAAVLLLVLWLRGWPLLFVILLVSALGLWEFYSLFWGPKGRITSRVCAIGLGWGMLCLTW
MNRPQDALVCLGAGFVLSAMSFLFRWDVVEEDNAFVSSGIFMAGLAYVPLLLLPATYLSTTKLIFVIAAVAISDTAAYFV
GTRFGHHKLWPRVSPKKSSEGAVGSLVACVIFCAIYGELYGKTGWLSFALLGIAVNAFAQVGDLFESALKRSVNVKDSGH
LLPGHGGVLDRADSLLFAMPMVAVVDQWFFFF

Sequences:

>Translated_272_residues
MPIEPTANPIDIRRIITGVLLAAVLLLVLWLRGWPLLFVILLVSALGLWEFYSLFWGPKGRITSRVCAIGLGWGMLCLTW
MNRPQDALVCLGAGFVLSAMSFLFRWDVVEEDNAFVSSGIFMAGLAYVPLLLLPATYLSTTKLIFVIAAVAISDTAAYFV
GTRFGHHKLWPRVSPKKSSEGAVGSLVACVIFCAIYGELYGKTGWLSFALLGIAVNAFAQVGDLFESALKRSVNVKDSGH
LLPGHGGVLDRADSLLFAMPMVAVVDQWFFFF
>Mature_271_residues
PIEPTANPIDIRRIITGVLLAAVLLLVLWLRGWPLLFVILLVSALGLWEFYSLFWGPKGRITSRVCAIGLGWGMLCLTWM
NRPQDALVCLGAGFVLSAMSFLFRWDVVEEDNAFVSSGIFMAGLAYVPLLLLPATYLSTTKLIFVIAAVAISDTAAYFVG
TRFGHHKLWPRVSPKKSSEGAVGSLVACVIFCAIYGELYGKTGWLSFALLGIAVNAFAQVGDLFESALKRSVNVKDSGHL
LPGHGGVLDRADSLLFAMPMVAVVDQWFFFF

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=128, Percent_Identity=42.96875, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787677, Length=145, Percent_Identity=39.3103448275862, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 29713; Mature: 29581

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PIEPTANPIDIRRIITGVLLAAVLLLVLWLRGWPLLFVILLVSALGLWEFYSLFWGPKG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
RITSRVCAIGLGWGMLCLTWMNRPQDALVCLGAGFVLSAMSFLFRWDVVEEDNAFVSSGI
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
FMAGLAYVPLLLLPATYLSTTKLIFVIAAVAISDTAAYFVGTRFGHHKLWPRVSPKKSSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GAVGSLVACVIFCAIYGELYGKTGWLSFALLGIAVNAFAQVGDLFESALKRSVNVKDSGH
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LLPGHGGVLDRADSLLFAMPMVAVVDQWFFFF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]