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The map label for this gene is hmeE [H]

Identifier: 220903727

GI number: 220903727

Start: 543114

End: 543494

Strand: Reverse

Name: hmeE [H]

Synonym: Ddes_0449

Alternate gene names: 220903727

Gene position: 543494-543114 (Counterclockwise)

Preceding gene: 220903728

Following gene: 220903726

Centisome position: 18.91

GC content: 52.76

Gene sequence:

>381_bases
ATGTATAACGCCAAAGCAGTTATCGTCGGAATCGTCATCTTTGTGGCCCTGTTTACCTCCCCTTTCTGGTTGAGCATGAT
GGGGCAGGACTATAAGAGCACAGGCATTGAGCTGCCCAAGGGCGAAAAGGAATGCATCGAGGACGTGCAGTTCATGCGCG
ACCAGCACATGCGCCTGCTCAATGAATGGCGCGATGAGGCCCTGCGCAAGGAAAACCGCGTTTATGTGGCCACCAGCGGC
AAAAAATGGACCATCAGCCTGCAGAATACCTGCTTGAAGTGCCACAGCAACTACAAGGAATTCTGTGAGAAGTGCCATAC
AGCCAACGGCGTTGATCCGTATTGCTGGACTTGCCACATCATTCCCCAGGGGAGCAAGTAA

Upstream 100 bases:

>100_bases
GAAGGGCGAGTGCAAGCGTACCATGGACCTGCGCCAGGAAGATCTGCCCAACGTGGCGGATGATGAGGATGCGCCCGAAG
CGCAGGGGGAGGGCCAATAA

Downstream 100 bases:

>100_bases
TGAACAAGAGCAGAAGAAGCTTTCTGAAAGTGGCGGGCTTTTCGGCCTTTGCCCTTACCAGCGGCATGGCTGCCCTGTCT
GGCGTGGCCCAGGCGCAGAT

Product: cytochrome c family protein

Products: NA

Alternate protein names: Hme subunit E [H]

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MYNAKAVIVGIVIFVALFTSPFWLSMMGQDYKSTGIELPKGEKECIEDVQFMRDQHMRLLNEWRDEALRKENRVYVATSG
KKWTISLQNTCLKCHSNYKEFCEKCHTANGVDPYCWTCHIIPQGSK

Sequences:

>Translated_126_residues
MYNAKAVIVGIVIFVALFTSPFWLSMMGQDYKSTGIELPKGEKECIEDVQFMRDQHMRLLNEWRDEALRKENRVYVATSG
KKWTISLQNTCLKCHSNYKEFCEKCHTANGVDPYCWTCHIIPQGSK
>Mature_126_residues
MYNAKAVIVGIVIFVALFTSPFWLSMMGQDYKSTGIELPKGEKECIEDVQFMRDQHMRLLNEWRDEALRKENRVYVATSG
KKWTISLQNTCLKCHSNYKEFCEKCHTANGVDPYCWTCHIIPQGSK

Specific function: Has menaquinol-oxidizing activity. HmeA, HmeB and HmeE subunits may together catalyze electron transfer from menaquinol to cytochrome c [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein; Extracellular side [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011031 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 14630; Mature: 14630

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS51008 MULTIHEME_CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
9.5 %Cys+Met (Translated Protein)
5.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
9.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNAKAVIVGIVIFVALFTSPFWLSMMGQDYKSTGIELPKGEKECIEDVQFMRDQHMRLL
CCCCHHHHHHHHHHHHHHHCHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
NEWRDEALRKENRVYVATSGKKWTISLQNTCLKCHSNYKEFCEKCHTANGVDPYCWTCHI
HHHHHHHHHHCCCEEEEECCCEEEEEHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEEEE
IPQGSK
ECCCCC
>Mature Secondary Structure
MYNAKAVIVGIVIFVALFTSPFWLSMMGQDYKSTGIELPKGEKECIEDVQFMRDQHMRLL
CCCCHHHHHHHHHHHHHHHCHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
NEWRDEALRKENRVYVATSGKKWTISLQNTCLKCHSNYKEFCEKCHTANGVDPYCWTCHI
HHHHHHHHHHCCCEEEEECCCEEEEEHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEEEE
IPQGSK
ECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9389475; 11952791 [H]