Click here to switch to the map view.

The map label for this gene is bioW [H]

Identifier: 220903702

GI number: 220903702

Start: 516053

End: 516760

Strand: Reverse

Name: bioW [H]

Synonym: Ddes_0424

Alternate gene names: 220903702

Gene position: 516760-516053 (Counterclockwise)

Preceding gene: 220903703

Following gene: 220903701

Centisome position: 17.98

GC content: 59.75

Gene sequence:

>708_bases
ATGCTGTACAGTATAAAAATGCGCGCTGAAAGCGGTTCACGGCACATTTCAGGGGCGGAGCGCATCGTGGAGCGCCGCGA
CATGGCTCAGGCCATGGATGCCCTGACCCGCCGGGGCATGGAGCATCCCAACGGCCCGGCCGAGGCGGTTACTGTTACAG
TGCGCCCCATAACGCGGCCCCTTATGCACATTCAGGCCCTGCCCGTGCATGAGCCGCACGTACGCGACCAGCATGAGGCC
CGGCAGGTCCTGACCGAAGAACTGCGGGGCATGGCTCTGGACCCATCCCCGGTGCTCGACCTGCTGTATAGTTTGCGCAA
GCCCATGCGCGGAGCTGTGCTTCTGGACGTGACCGGCATGAAACGTCTGGAACCTGATCCGCAACGGGGGGTGCGGGCAA
CGTGCATGGATTACACGGGTAACAGATGTGAAGGCAAAAACCATTTCAGGGAGGCCCTCTGCCTTGCCAGCAAGGTGGCC
CACTGCCCCCAGATCATCGGCGAACTGTGCATCTCTGACGATCCGGATTATACCACAGGCTACTTTGCCTCACAGGTCAG
AGGCTACGTGCGCATCCATCACATCAAACAAGCCGGACAACAGTTGGGCGGGCGCATTTTTCTTTTCAGGGGCCAGCAGG
CCGAGATCGGACAGTGTGTGGACTACCTTGAAAACCAGCCGGTCATGGTTGTTATGGAGTCTCTGTGA

Upstream 100 bases:

>100_bases
AGACTGCACCGCGAAGCAGACCGGGCCGCAAAAACTCCGGGGCCGCCGCACCGGCGGCAGGCGCGGCACGGCGCAATGGC
ATCCGTAAAAGGTAAAGAGC

Downstream 100 bases:

>100_bases
GCGACGTTGCCGCCAGGCTCGAAACCATCAGGGCCGCGCACCTGTACCGGCGCCTGCGCACGCTTTCCACACCGCAGGAC
AGGGAAGTCGTCATCGACGG

Product: 6-carboxyhexanoate--CoA ligase

Products: NA

Alternate protein names: Pimeloyl-CoA synthase [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MLYSIKMRAESGSRHISGAERIVERRDMAQAMDALTRRGMEHPNGPAEAVTVTVRPITRPLMHIQALPVHEPHVRDQHEA
RQVLTEELRGMALDPSPVLDLLYSLRKPMRGAVLLDVTGMKRLEPDPQRGVRATCMDYTGNRCEGKNHFREALCLASKVA
HCPQIIGELCISDDPDYTTGYFASQVRGYVRIHHIKQAGQQLGGRIFLFRGQQAEIGQCVDYLENQPVMVVMESL

Sequences:

>Translated_235_residues
MLYSIKMRAESGSRHISGAERIVERRDMAQAMDALTRRGMEHPNGPAEAVTVTVRPITRPLMHIQALPVHEPHVRDQHEA
RQVLTEELRGMALDPSPVLDLLYSLRKPMRGAVLLDVTGMKRLEPDPQRGVRATCMDYTGNRCEGKNHFREALCLASKVA
HCPQIIGELCISDDPDYTTGYFASQVRGYVRIHHIKQAGQQLGGRIFLFRGQQAEIGQCVDYLENQPVMVVMESL
>Mature_235_residues
MLYSIKMRAESGSRHISGAERIVERRDMAQAMDALTRRGMEHPNGPAEAVTVTVRPITRPLMHIQALPVHEPHVRDQHEA
RQVLTEELRGMALDPSPVLDLLYSLRKPMRGAVLLDVTGMKRLEPDPQRGVRATCMDYTGNRCEGKNHFREALCLASKVA
HCPQIIGELCISDDPDYTTGYFASQVRGYVRIHHIKQAGQQLGGRIFLFRGQQAEIGQCVDYLENQPVMVVMESL

Specific function: Transforms pimelate into pimeloyl-CoA [H]

COG id: COG1424

COG function: function code H; Pimeloyl-CoA synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BioW family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005499
- ProDom:   PD017229 [H]

Pfam domain/function: PF03744 BioW [H]

EC number: =6.2.1.14 [H]

Molecular weight: Translated: 26439; Mature: 26439

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYSIKMRAESGSRHISGAERIVERRDMAQAMDALTRRGMEHPNGPAEAVTVTVRPITRP
CEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHH
LMHIQALPVHEPHVRDQHEARQVLTEELRGMALDPSPVLDLLYSLRKPMRGAVLLDVTGM
HHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCC
KRLEPDPQRGVRATCMDYTGNRCEGKNHFREALCLASKVAHCPQIIGELCISDDPDYTTG
HHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
YFASQVRGYVRIHHIKQAGQQLGGRIFLFRGQQAEIGQCVDYLENQPVMVVMESL
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCEEEEEECC
>Mature Secondary Structure
MLYSIKMRAESGSRHISGAERIVERRDMAQAMDALTRRGMEHPNGPAEAVTVTVRPITRP
CEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHH
LMHIQALPVHEPHVRDQHEARQVLTEELRGMALDPSPVLDLLYSLRKPMRGAVLLDVTGM
HHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCC
KRLEPDPQRGVRATCMDYTGNRCEGKNHFREALCLASKVAHCPQIIGELCISDDPDYTTG
HHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
YFASQVRGYVRIHHIKQAGQQLGGRIFLFRGQQAEIGQCVDYLENQPVMVVMESL
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]