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The map label for this gene is yfnA [H]

Identifier: 220903502

GI number: 220903502

Start: 275079

End: 276551

Strand: Direct

Name: yfnA [H]

Synonym: Ddes_0221

Alternate gene names: 220903502

Gene position: 275079-276551 (Clockwise)

Preceding gene: 220903501

Following gene: 220903505

Centisome position: 9.57

GC content: 53.84

Gene sequence:

>1473_bases
ATGTCACAAGTTCATGAATCCCGACCGGTCTTGGAAAAAAATATGTCCCCGTTGTCCATATGGGCGTTAGCATTCGGCGC
GATTATCGGATGGGGAGCCTTCATTATGCCCGGCTTGCGGTTTTTGCCGGGATCTGGGCCGATCGGTGCCTGCATAGGTT
TTGTATGCGGGGGCCTGTTGCTCATGTTTATAGCGGTGAGTTACGGTAAAGTTGTGGGGCTTTACCCTGTGGCTGGAGGT
GTTTTTGCTTTTGCCTACGCGGCATTCGGGCCGGGGCTGGCCTTTGTCGGCGGGTGGGCGCTGCTTTTGGGCTACCTATG
CATAATCGCCCTCAACGGCACTGCCATCGTGCTGTTGACGCGTTTTCTCATCCCCGGTGTTCTGGAACTGGGGTATATGT
ACAGCATTGCTGAATGGAAAATATATTTCGGTGAGCTATTATTTCTGGAAGCCGTGTTGGCGCTGTTCTGGTATCTCAAT
TACAGGGGCGCGGATGTCGTAAGTAAAGTGCAGGTTGTGCTTGCGGTGATACTGGCTATCGGCGTGCTTGCTCTTCTTGT
GGGGGCTATCGTGTCGCCGACAAGCCAGTGGCAGAATATCGAGCCGTGGTTTGCGCAGGACAAGTCGGTCATTGCCTCCA
TAGCAGCGGTCACGGCTATTGCCCCCTGGCTTTTTGTGGGCTTTGACACTATCCCGCAGGCTGCGGAGGAATTTAATTTT
TCCGCAAAAACGGGCGTGCGGCTCATGCTTTTGTCCATTGTCTGCGGTATCGTCACTTACAGCATCATTACCCTGGCCGT
AGCCGCTGTTATTCCCTACCAGGAACTGCTGGCGCTCAATCCTGTCTGGCACACGGGGTATACCGTCAGTCTTTCACTGG
GCAAGGTCGGCAGTATAGTGCTTGCGCTTGCAGTGCTTTCAGCCATTCTGACCGGTATTAACGGCTTTTTCATCGCCAGT
TCAAGGCTTATGTTCAGCATGGGGCGCGCTCACATTTTGCCGGTGTGGTTCTCCTCGCTGCACAAAACGCACAAGACCCC
GCACAACGCGCTCAACTTTACCCTTGTTGTCGTGGCGATTGCGCCCTTCTTCGGCCGTGAAGTTTTGTCCTGGGTTGTGG
ATATGTCTTCAATCGGCACTATCGTGGCCTACTTTTTTGCTTCGGCGTCCGCTTTTGTGATCATGCGCAAGCATGAAGAT
AATTGTAATATAAGCGGCATACTTGGCTGCATGGCTTCTTTGGTCTGCCTGGGGCTGCTGACGCTGCCCATGTCTCCTGC
CTGCATCGGGCCGGAGTCGTGGCACGTGCTGGTTGCCTGGTTTATCCTGGGCGTTTTTTTCTACATCGTGCGGTACAAGG
CTGTACACGCCATTTCTGAAGAAGAGCGCACGTATATGATCCTGGGCGAATCTGACCTGAAGGAGCATATAGCCCAGCGG
GCAGCCTCAAAGCCTGATCAGCTTGCGGCGTAG

Upstream 100 bases:

>100_bases
TTCAGATACGGCGATTTTTTTGCGCTCCACAACTTTTTATGCCAGCAATTTTATTGCCTGAAGCGCCACGGAAGGTGCCA
AAACCGAGGAGAACTGTTGT

Downstream 100 bases:

>100_bases
TATGGAAAGAGTACTTTTCTGGCAGGAGATGCAATAGCTTTGTTAGCCTTGCTGTCTACACGCCAATGTTTCCCATGACC
ATGCGCATGGGGAATCCCGC

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MSQVHESRPVLEKNMSPLSIWALAFGAIIGWGAFIMPGLRFLPGSGPIGACIGFVCGGLLLMFIAVSYGKVVGLYPVAGG
VFAFAYAAFGPGLAFVGGWALLLGYLCIIALNGTAIVLLTRFLIPGVLELGYMYSIAEWKIYFGELLFLEAVLALFWYLN
YRGADVVSKVQVVLAVILAIGVLALLVGAIVSPTSQWQNIEPWFAQDKSVIASIAAVTAIAPWLFVGFDTIPQAAEEFNF
SAKTGVRLMLLSIVCGIVTYSIITLAVAAVIPYQELLALNPVWHTGYTVSLSLGKVGSIVLALAVLSAILTGINGFFIAS
SRLMFSMGRAHILPVWFSSLHKTHKTPHNALNFTLVVVAIAPFFGREVLSWVVDMSSIGTIVAYFFASASAFVIMRKHED
NCNISGILGCMASLVCLGLLTLPMSPACIGPESWHVLVAWFILGVFFYIVRYKAVHAISEEERTYMILGESDLKEHIAQR
AASKPDQLAA

Sequences:

>Translated_490_residues
MSQVHESRPVLEKNMSPLSIWALAFGAIIGWGAFIMPGLRFLPGSGPIGACIGFVCGGLLLMFIAVSYGKVVGLYPVAGG
VFAFAYAAFGPGLAFVGGWALLLGYLCIIALNGTAIVLLTRFLIPGVLELGYMYSIAEWKIYFGELLFLEAVLALFWYLN
YRGADVVSKVQVVLAVILAIGVLALLVGAIVSPTSQWQNIEPWFAQDKSVIASIAAVTAIAPWLFVGFDTIPQAAEEFNF
SAKTGVRLMLLSIVCGIVTYSIITLAVAAVIPYQELLALNPVWHTGYTVSLSLGKVGSIVLALAVLSAILTGINGFFIAS
SRLMFSMGRAHILPVWFSSLHKTHKTPHNALNFTLVVVAIAPFFGREVLSWVVDMSSIGTIVAYFFASASAFVIMRKHED
NCNISGILGCMASLVCLGLLTLPMSPACIGPESWHVLVAWFILGVFFYIVRYKAVHAISEEERTYMILGESDLKEHIAQR
AASKPDQLAA
>Mature_489_residues
SQVHESRPVLEKNMSPLSIWALAFGAIIGWGAFIMPGLRFLPGSGPIGACIGFVCGGLLLMFIAVSYGKVVGLYPVAGGV
FAFAYAAFGPGLAFVGGWALLLGYLCIIALNGTAIVLLTRFLIPGVLELGYMYSIAEWKIYFGELLFLEAVLALFWYLNY
RGADVVSKVQVVLAVILAIGVLALLVGAIVSPTSQWQNIEPWFAQDKSVIASIAAVTAIAPWLFVGFDTIPQAAEEFNFS
AKTGVRLMLLSIVCGIVTYSIITLAVAAVIPYQELLALNPVWHTGYTVSLSLGKVGSIVLALAVLSAILTGINGFFIASS
RLMFSMGRAHILPVWFSSLHKTHKTPHNALNFTLVVVAIAPFFGREVLSWVVDMSSIGTIVAYFFASASAFVIMRKHEDN
CNISGILGCMASLVCLGLLTLPMSPACIGPESWHVLVAWFILGVFFYIVRYKAVHAISEEERTYMILGESDLKEHIAQRA
ASKPDQLAA

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI87082023, Length=310, Percent_Identity=25.4838709677419, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87081869, Length=346, Percent_Identity=23.121387283237, Blast_Score=65, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24668806, Length=427, Percent_Identity=23.4192037470726, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21356285, Length=427, Percent_Identity=23.4192037470726, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24668802, Length=427, Percent_Identity=23.4192037470726, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI221512776, Length=423, Percent_Identity=23.1678486997636, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24666159, Length=423, Percent_Identity=23.1678486997636, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 52801; Mature: 52670

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCCCCCCC
>Mature Secondary Structure 
SQVHESRPVLEKNMSPLSIWALAFGAIIGWGAFIMPGLRFLPGSGPIGACIGFVCGGLL
CCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHH
LMFIAVSYGKVVGLYPVAGGVFAFAYAAFGPGLAFVGGWALLLGYLCIIALNGTAIVLLT
HHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RFLIPGVLELGYMYSIAEWKIYFGELLFLEAVLALFWYLNYRGADVVSKVQVVLAVILAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GVLALLVGAIVSPTSQWQNIEPWFAQDKSVIASIAAVTAIAPWLFVGFDTIPQAAEEFNF
HHHHHHHHHHHCCCHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SAKTGVRLMLLSIVCGIVTYSIITLAVAAVIPYQELLALNPVWHTGYTVSLSLGKVGSIV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCEEEEEEHHHHHHHH
LALAVLSAILTGINGFFIASSRLMFSMGRAHILPVWFSSLHKTHKTPHNALNFTLVVVAI
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
APFFGREVLSWVVDMSSIGTIVAYFFASASAFVIMRKHEDNCNISGILGCMASLVCLGLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
TLPMSPACIGPESWHVLVAWFILGVFFYIVRYKAVHAISEEERTYMILGESDLKEHIAQR
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHH
AASKPDQLAA
HCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]