Click here to switch to the map view.

The map label for this gene is nhaA1 [H]

Identifier: 220903305

GI number: 220903305

Start: 24564

End: 25394

Strand: Direct

Name: nhaA1 [H]

Synonym: Ddes_0019

Alternate gene names: 220903305

Gene position: 24564-25394 (Clockwise)

Preceding gene: 220903304

Following gene: 220903312

Centisome position: 0.85

GC content: 52.95

Gene sequence:

>831_bases
ATGACAGTATTTAAAAAAGCAGGGGCCGTAGCCCTTTTGGGCTTGATGACTTTTGGGGGTTGGGCGCTGCTGGCGCAGCA
AGGTGCACGGGCCGCTTCTGTTCAGGTGACGGAAGAAAACCTGCCGCAAATGCTGGAAAAACTTTTTCAGGAGCGGCCGG
ATCTTGTTATGGACGTGCTGCGCAAACATAGCGAAGCCGTGCTTGATATTGCGCAGCAGGGTTCAAACCTGCGCCGCCAG
CGCAGCCTTGAAGCGCAATGGAACCAGGAAATGAAAACGCCCAAGCCCGTCAAGGTGGAGGGGCGCCCCGTGCTTGGGGC
AAAAAACGCCAAGGTGCGTATAGTGGCGTTTTCTGACTTTACCTGCCATTTCTGCCAGCAGGCCGCGGGCACAGTGAGCG
GCATCATGAAAGAATATGGCAAGGACGTGAGCCTGGTATTCAAAAACCTGCCGCTGGACGAAAAGGGGCCGGCCAGTATC
GCGTCCAGATATTTTCTTGCTGTAGCCCAGCAGAGCGAAGAAAAAGCCTGGAAATTTCATGACGCGCTTTTTGCTGACAG
AAACCGGCTCGTCACCGAAGGCGAAACTTTTTTGAAAAAGACCGCCCAGGACCTCGGCGTAGATATGAAACGCCTTGCCA
AAGACGTACACAGCAAAAAAATTTCTGATATTATGGACGAAGATCAGCAGGACGCGCAAAAACTGGGCGTGGAAGGAACA
CCGTATTTCTTGGTCAACGACCTCGTGGTACGGGGAGCGCTGCCGCCCGATCTTTTCAAAAGAGCGGTGGATATGGCTAA
AAATCAGGCAGACAACAAGTCCGCAAAATAA

Upstream 100 bases:

>100_bases
GCTGCTGTTTAAAATCGAAGATGCCGCAACGCAATGCCGCCTTGAGGCGGAGCAGGGTGGCGCCAATAATCCGTCTTGAT
AGACGTTGACAGGATGTTTT

Downstream 100 bases:

>100_bases
AGCACAGAGCTGCTTGTCAATATGTCATGATGTTCCGGATAATTTTGTTTTTTGCTCAAAGAAGAGCAGAGCGGGATAGA
GCGGGCATAAAGCCGGGTAG

Product: DSBA oxidoreductase

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA 1 [H]

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MTVFKKAGAVALLGLMTFGGWALLAQQGARAASVQVTEENLPQMLEKLFQERPDLVMDVLRKHSEAVLDIAQQGSNLRRQ
RSLEAQWNQEMKTPKPVKVEGRPVLGAKNAKVRIVAFSDFTCHFCQQAAGTVSGIMKEYGKDVSLVFKNLPLDEKGPASI
ASRYFLAVAQQSEEKAWKFHDALFADRNRLVTEGETFLKKTAQDLGVDMKRLAKDVHSKKISDIMDEDQQDAQKLGVEGT
PYFLVNDLVVRGALPPDLFKRAVDMAKNQADNKSAK

Sequences:

>Translated_276_residues
MTVFKKAGAVALLGLMTFGGWALLAQQGARAASVQVTEENLPQMLEKLFQERPDLVMDVLRKHSEAVLDIAQQGSNLRRQ
RSLEAQWNQEMKTPKPVKVEGRPVLGAKNAKVRIVAFSDFTCHFCQQAAGTVSGIMKEYGKDVSLVFKNLPLDEKGPASI
ASRYFLAVAQQSEEKAWKFHDALFADRNRLVTEGETFLKKTAQDLGVDMKRLAKDVHSKKISDIMDEDQQDAQKLGVEGT
PYFLVNDLVVRGALPPDLFKRAVDMAKNQADNKSAK
>Mature_275_residues
TVFKKAGAVALLGLMTFGGWALLAQQGARAASVQVTEENLPQMLEKLFQERPDLVMDVLRKHSEAVLDIAQQGSNLRRQR
SLEAQWNQEMKTPKPVKVEGRPVLGAKNAKVRIVAFSDFTCHFCQQAAGTVSGIMKEYGKDVSLVFKNLPLDEKGPASIA
SRYFLAVAQQSEEKAWKFHDALFADRNRLVTEGETFLKKTAQDLGVDMKRLAKDVHSKKISDIMDEDQQDAQKLGVEGTP
YFLVNDLVVRGALPPDLFKRAVDMAKNQADNKSAK

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 30663; Mature: 30531

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVFKKAGAVALLGLMTFGGWALLAQQGARAASVQVTEENLPQMLEKLFQERPDLVMDVL
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEECHHHHHHHHHHHHHHCCHHHHHHH
RKHSEAVLDIAQQGSNLRRQRSLEAQWNQEMKTPKPVKVEGRPVLGAKNAKVRIVAFSDF
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCEECCCCCEEEEEEECCH
TCHFCQQAAGTVSGIMKEYGKDVSLVFKNLPLDEKGPASIASRYFLAVAQQSEEKAWKFH
HHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DALFADRNRLVTEGETFLKKTAQDLGVDMKRLAKDVHSKKISDIMDEDQQDAQKLGVEGT
HHHHHHCCCHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCC
PYFLVNDLVVRGALPPDLFKRAVDMAKNQADNKSAK
CHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TVFKKAGAVALLGLMTFGGWALLAQQGARAASVQVTEENLPQMLEKLFQERPDLVMDVL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEECHHHHHHHHHHHHHHCCHHHHHHH
RKHSEAVLDIAQQGSNLRRQRSLEAQWNQEMKTPKPVKVEGRPVLGAKNAKVRIVAFSDF
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCEECCCCCEEEEEEECCH
TCHFCQQAAGTVSGIMKEYGKDVSLVFKNLPLDEKGPASIASRYFLAVAQQSEEKAWKFH
HHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DALFADRNRLVTEGETFLKKTAQDLGVDMKRLAKDVHSKKISDIMDEDQQDAQKLGVEGT
HHHHHHCCCHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCC
PYFLVNDLVVRGALPPDLFKRAVDMAKNQADNKSAK
CHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA