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The map label for this gene is dppE [H]

Identifier: 218904711

GI number: 218904711

Start: 3431517

End: 3433223

Strand: Reverse

Name: dppE [H]

Synonym: BCAH820_3595

Alternate gene names: 218904711

Gene position: 3433223-3431517 (Counterclockwise)

Preceding gene: 218904712

Following gene: 218904707

Centisome position: 64.75

GC content: 35.21

Gene sequence:

>1707_bases
ATGAAGAAAAAGATGAAAAAGTTCACGGCGGTTGTGGCGCCAGTTTTAGCGATGAGTATGGCGTTGACAGCTTGTTCTGG
ATCTGGTGGGGAGAAGAAATCAACTACGACGTCTAGTGGTGGTGGGGAAGAGAAAAAGTCTGAAATTAAATACGCAGCAA
AACAAGTGTTAAATCGTACAGAGAATCAAGAGATTCCGACGATGGATGTTTCAAAATCTACTGATACATTAGGTTCTCAA
ATTTTAGGGAACACGATGGAAGGTTTATATCGATTAGATAAAGATAATAAGCCAATCCCAGCTGCAGCAGAATCTAGTAC
GAAAAGCGAGGATGGCAAAAAATATACATTTAAATTACGTAAAGATGCAAAATGGTCAAATGGTGATCCTGTAACAGCGA
AAGATTTCGTATACGCATGGCAGCGCTTACTTGATAAAAATACAGCTGCAGAATATGCGTTTATTGCCTTCTATATTAAA
AACGCAGAAGCAATTAATAAAGGTGAAAAGCCACTAACAGATTTAGGAGCAAAAGCGGTAGATGATTATACGCTAGAAGT
AGAATTAGAGAAACCAGTACCATATTTCTTGAATTTAATGGCATTCCCATCTTACTATCCATTAAATGAAAAGTTCGTAA
AAGAAAAAGGAGATAAATTCGGTTTAGAAGCAGATACAACGTTGTATAACGGACCGTTCGTTATGGCTTCATGGAAACAT
GAACAAGGATGGCAGCTAAAGAAAAATGATAAGTACTGGGATAATAAGACTGTAAAATTAGAAGAAATTAACTATAGTGT
AGTAAAAGAAGTTGCGACGAAAGTAAACTTATATGATACAGGATCAATTGATTTCACACTATTATCAGGGGAATTCGTTG
ATAAATATAAATCGAATAAAGAAGAGTATGGTGAATATTCAGAAGCAAGTACATTCTTCTTACGTTTAAATCAAAAACGT
AATGGACAAGATACACCGTTAAAGAGCAAAAAACTTCGTGAAGCGATTGCATTATCAATTGATAAAAAAGGATTAGCAAA
TGTTATTTTAAATAACGGTTCAAAAGCAACAGATCAATTAGTACCAAAAGGACTTGCGACAGGACCAGACGGTAAAGATT
ACCAAGATACATTTAAAAACGGTCTAAAATATGATCCGAAAAAAGGTGCAGCAGCTTGGGAAGCAGCGAAAAAAGAACTT
GGTAAAGATCAAGTGACAATTGAATTACTAAGCTATGATGATGGAACTGCGAAAAAAATTGCTGACTACTTTAAAGATCA
AATTGAGAAAAACTTAAAAGGTGTAACGGTTAACACGAAAATTCAACCGTTCAAACAAAAACTAAAATTAGAGTCAGCAC
AAGATTATGAAGTTTCGTTTGCAGGTTGGAGTCCAGATTATTCGGATCCAATGACATTTATTGATATGTTTGAATCGAAG
AGCCCATATAACCAAATGAGTTATTCGAATCCAAAATATGATGAAATGGTAGCGAAAGCAGGTAATGAATTACTGTCTGA
TCCGAAGAAGCGTTGGGAAACGTTAGGAAAAGCAGAGAAATTATTCCTTGAAGAAGATGCAGGATTAGTTCCTTTATATC
AAACAGGAAGAGCGTATGTAATGAAACCGAATGTAAAAGGAATTGTGAAACATAACATTAGTCCAGAATATAGCTTTAAG
TGGGCTTATGTAACGGAAGGTAAATAA

Upstream 100 bases:

>100_bases
AAAATTAGTAGAATATTAATTAATAAGAATTTTCTGATAACTAGTTATTAGAAAATCTATCAAAATTAGTTTCGTACATA
TAATTGGGGAGGCTACAAAA

Downstream 100 bases:

>100_bases
TAAAAAAGAGCGTGTTTAAAAGTAGATATGAAGTGACCCCTAAAAGTTAGACACGGTTATTTCATTAGGCAGCTTGATAA
AAGTGAGTTCGGTATTGTAT

Product: putative oligopeptide ABC transporter, oligopeptide-binding protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 568; Mature: 568

Protein sequence:

>568_residues
MKKKMKKFTAVVAPVLAMSMALTACSGSGGEKKSTTTSSGGGEEKKSEIKYAAKQVLNRTENQEIPTMDVSKSTDTLGSQ
ILGNTMEGLYRLDKDNKPIPAAAESSTKSEDGKKYTFKLRKDAKWSNGDPVTAKDFVYAWQRLLDKNTAAEYAFIAFYIK
NAEAINKGEKPLTDLGAKAVDDYTLEVELEKPVPYFLNLMAFPSYYPLNEKFVKEKGDKFGLEADTTLYNGPFVMASWKH
EQGWQLKKNDKYWDNKTVKLEEINYSVVKEVATKVNLYDTGSIDFTLLSGEFVDKYKSNKEEYGEYSEASTFFLRLNQKR
NGQDTPLKSKKLREAIALSIDKKGLANVILNNGSKATDQLVPKGLATGPDGKDYQDTFKNGLKYDPKKGAAAWEAAKKEL
GKDQVTIELLSYDDGTAKKIADYFKDQIEKNLKGVTVNTKIQPFKQKLKLESAQDYEVSFAGWSPDYSDPMTFIDMFESK
SPYNQMSYSNPKYDEMVAKAGNELLSDPKKRWETLGKAEKLFLEEDAGLVPLYQTGRAYVMKPNVKGIVKHNISPEYSFK
WAYVTEGK

Sequences:

>Translated_568_residues
MKKKMKKFTAVVAPVLAMSMALTACSGSGGEKKSTTTSSGGGEEKKSEIKYAAKQVLNRTENQEIPTMDVSKSTDTLGSQ
ILGNTMEGLYRLDKDNKPIPAAAESSTKSEDGKKYTFKLRKDAKWSNGDPVTAKDFVYAWQRLLDKNTAAEYAFIAFYIK
NAEAINKGEKPLTDLGAKAVDDYTLEVELEKPVPYFLNLMAFPSYYPLNEKFVKEKGDKFGLEADTTLYNGPFVMASWKH
EQGWQLKKNDKYWDNKTVKLEEINYSVVKEVATKVNLYDTGSIDFTLLSGEFVDKYKSNKEEYGEYSEASTFFLRLNQKR
NGQDTPLKSKKLREAIALSIDKKGLANVILNNGSKATDQLVPKGLATGPDGKDYQDTFKNGLKYDPKKGAAAWEAAKKEL
GKDQVTIELLSYDDGTAKKIADYFKDQIEKNLKGVTVNTKIQPFKQKLKLESAQDYEVSFAGWSPDYSDPMTFIDMFESK
SPYNQMSYSNPKYDEMVAKAGNELLSDPKKRWETLGKAEKLFLEEDAGLVPLYQTGRAYVMKPNVKGIVKHNISPEYSFK
WAYVTEGK
>Mature_568_residues
MKKKMKKFTAVVAPVLAMSMALTACSGSGGEKKSTTTSSGGGEEKKSEIKYAAKQVLNRTENQEIPTMDVSKSTDTLGSQ
ILGNTMEGLYRLDKDNKPIPAAAESSTKSEDGKKYTFKLRKDAKWSNGDPVTAKDFVYAWQRLLDKNTAAEYAFIAFYIK
NAEAINKGEKPLTDLGAKAVDDYTLEVELEKPVPYFLNLMAFPSYYPLNEKFVKEKGDKFGLEADTTLYNGPFVMASWKH
EQGWQLKKNDKYWDNKTVKLEEINYSVVKEVATKVNLYDTGSIDFTLLSGEFVDKYKSNKEEYGEYSEASTFFLRLNQKR
NGQDTPLKSKKLREAIALSIDKKGLANVILNNGSKATDQLVPKGLATGPDGKDYQDTFKNGLKYDPKKGAAAWEAAKKEL
GKDQVTIELLSYDDGTAKKIADYFKDQIEKNLKGVTVNTKIQPFKQKLKLESAQDYEVSFAGWSPDYSDPMTFIDMFESK
SPYNQMSYSNPKYDEMVAKAGNELLSDPKKRWETLGKAEKLFLEEDAGLVPLYQTGRAYVMKPNVKGIVKHNISPEYSFK
WAYVTEGK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=511, Percent_Identity=31.5068493150685, Blast_Score=229, Evalue=5e-61,
Organism=Escherichia coli, GI1789397, Length=509, Percent_Identity=29.2730844793713, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI87081878, Length=535, Percent_Identity=28.0373831775701, Blast_Score=192, Evalue=6e-50,
Organism=Escherichia coli, GI1787762, Length=455, Percent_Identity=28.1318681318681, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI1787052, Length=512, Percent_Identity=23.046875, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789887, Length=336, Percent_Identity=26.7857142857143, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789966, Length=483, Percent_Identity=22.9813664596273, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 63826; Mature: 63826

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKMKKFTAVVAPVLAMSMALTACSGSGGEKKSTTTSSGGGEEKKSEIKYAAKQVLNRT
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
ENQEIPTMDVSKSTDTLGSQILGNTMEGLYRLDKDNKPIPAAAESSTKSEDGKKYTFKLR
CCCCCCCEECCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCEEEEEEE
KDAKWSNGDPVTAKDFVYAWQRLLDKNTAAEYAFIAFYIKNAEAINKGEKPLTDLGAKAV
CCCCCCCCCCCCHHHHHHHHHHHHCCCCHHCEEEEEEEEECHHHHCCCCCCHHHHCCHHC
DDYTLEVELEKPVPYFLNLMAFPSYYPLNEKFVKEKGDKFGLEADTTLYNGPFVMASWKH
CCEEEEEEECCCCHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCEEECCCEEEEECCC
EQGWQLKKNDKYWDNKTVKLEEINYSVVKEVATKVNLYDTGSIDFTLLSGEFVDKYKSNK
CCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCEEECCCEEEEEECCHHHHHHHCCH
EEYGEYSEASTFFLRLNQKRNGQDTPLKSKKLREAIALSIDKKGLANVILNNGSKATDQL
HHHCCHHCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHEECCCCHHHHHH
VPKGLATGPDGKDYQDTFKNGLKYDPKKGAAAWEAAKKELGKDQVTIELLSYDDGTAKKI
CCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCHHHHH
ADYFKDQIEKNLKGVTVNTKIQPFKQKLKLESAQDYEVSFAGWSPDYSDPMTFIDMFESK
HHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCC
SPYNQMSYSNPKYDEMVAKAGNELLSDPKKRWETLGKAEKLFLEEDAGLVPLYQTGRAYV
CCCCCCCCCCCCHHHHHHHHCHHHHCCHHHHHHHHCHHHHHHEECCCCEEEEEECCCEEE
MKPNVKGIVKHNISPEYSFKWAYVTEGK
ECCCCCEEEECCCCCCCEEEEEEEECCC
>Mature Secondary Structure
MKKKMKKFTAVVAPVLAMSMALTACSGSGGEKKSTTTSSGGGEEKKSEIKYAAKQVLNRT
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
ENQEIPTMDVSKSTDTLGSQILGNTMEGLYRLDKDNKPIPAAAESSTKSEDGKKYTFKLR
CCCCCCCEECCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCEEEEEEE
KDAKWSNGDPVTAKDFVYAWQRLLDKNTAAEYAFIAFYIKNAEAINKGEKPLTDLGAKAV
CCCCCCCCCCCCHHHHHHHHHHHHCCCCHHCEEEEEEEEECHHHHCCCCCCHHHHCCHHC
DDYTLEVELEKPVPYFLNLMAFPSYYPLNEKFVKEKGDKFGLEADTTLYNGPFVMASWKH
CCEEEEEEECCCCHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCEEECCCEEEEECCC
EQGWQLKKNDKYWDNKTVKLEEINYSVVKEVATKVNLYDTGSIDFTLLSGEFVDKYKSNK
CCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCEEECCCEEEEEECCHHHHHHHCCH
EEYGEYSEASTFFLRLNQKRNGQDTPLKSKKLREAIALSIDKKGLANVILNNGSKATDQL
HHHCCHHCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHEECCCCHHHHHH
VPKGLATGPDGKDYQDTFKNGLKYDPKKGAAAWEAAKKELGKDQVTIELLSYDDGTAKKI
CCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCHHHHH
ADYFKDQIEKNLKGVTVNTKIQPFKQKLKLESAQDYEVSFAGWSPDYSDPMTFIDMFESK
HHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCC
SPYNQMSYSNPKYDEMVAKAGNELLSDPKKRWETLGKAEKLFLEEDAGLVPLYQTGRAYV
CCCCCCCCCCCCHHHHHHHHCHHHHCCHHHHHHHHCHHHHHHEECCCCEEEEEECCCEEE
MKPNVKGIVKHNISPEYSFKWAYVTEGK
ECCCCCEEEECCCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]