Click here to switch to the map view.

The map label for this gene is moaE2 [H]

Identifier: 218904689

GI number: 218904689

Start: 3406571

End: 3407035

Strand: Reverse

Name: moaE2 [H]

Synonym: BCAH820_3573

Alternate gene names: 218904689

Gene position: 3407035-3406571 (Counterclockwise)

Preceding gene: 218904690

Following gene: 218904688

Centisome position: 64.25

GC content: 38.92

Gene sequence:

>465_bases
ATGGGACAAGTGCTATTTGAAATTGTAGATATACCGATTGTAGTTGAAGAAGTAACGAATAAGGTTGCAAGAAGAGAAGC
AGGTGCGATTACAACTTTTATTGGTACAGTGAGAGAATTAACAAAAGGAAAACGAACGCTGCATTTAGAGTATGAAGCAT
ATAAACCGATGGCAGTAAAACAACTTACGAGAATTGGGGAAGAAATAAATGAAAAGTGGCCAGATGCGAAAGTAGCAATT
ACGCACCGAGTAGGACGGCTAGAAATAATGGATATTGCGGTAGTCATTGCAGTTTCATCACCGCATCGCAAAGTAGCTTA
TGAAGCGAATGAATACGCGATTGAACGTATAAAACGAATCGTCCCAATTTGGAAAAAAGAATTTTGGGACGATGGAACGA
TGTGGATTGGAGATCAACTTGAAAATACACCTTATCCAGAAGGAAAACCGAAGAAGGAAGAATGA

Upstream 100 bases:

>100_bases
AGAGGTTATAAAAAAGATATGTTCGTAGATGTGCTCTTGTTGGAAGATAACGAAGGTAGTGAATGGCCTTGGACATTTTA
TAAAGTGAGAGGTGATTCTA

Downstream 100 bases:

>100_bases
GAAAATGATTACAATTTTACTGTTCGCAAATTTGCGTGAGGAAGTCGGATTAGACCGATTAGTAATTTCCGAAAAACAAG
AAATGACTGTGCAGCAATTA

Product: molybdopterin converting factor, subunit 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MGQVLFEIVDIPIVVEEVTNKVARREAGAITTFIGTVRELTKGKRTLHLEYEAYKPMAVKQLTRIGEEINEKWPDAKVAI
THRVGRLEIMDIAVVIAVSSPHRKVAYEANEYAIERIKRIVPIWKKEFWDDGTMWIGDQLENTPYPEGKPKKEE

Sequences:

>Translated_154_residues
MGQVLFEIVDIPIVVEEVTNKVARREAGAITTFIGTVRELTKGKRTLHLEYEAYKPMAVKQLTRIGEEINEKWPDAKVAI
THRVGRLEIMDIAVVIAVSSPHRKVAYEANEYAIERIKRIVPIWKKEFWDDGTMWIGDQLENTPYPEGKPKKEE
>Mature_153_residues
GQVLFEIVDIPIVVEEVTNKVARREAGAITTFIGTVRELTKGKRTLHLEYEAYKPMAVKQLTRIGEEINEKWPDAKVAIT
HRVGRLEIMDIAVVIAVSSPHRKVAYEANEYAIERIKRIVPIWKKEFWDDGTMWIGDQLENTPYPEGKPKKEE

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=127, Percent_Identity=41.7322834645669, Blast_Score=116, Evalue=8e-27,
Organism=Escherichia coli, GI1787003, Length=123, Percent_Identity=35.7723577235772, Blast_Score=80, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17509279, Length=127, Percent_Identity=37.7952755905512, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21356259, Length=125, Percent_Identity=41.6, Blast_Score=109, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17716; Mature: 17585

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQVLFEIVDIPIVVEEVTNKVARREAGAITTFIGTVRELTKGKRTLHLEYEAYKPMAVK
CCHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHH
QLTRIGEEINEKWPDAKVAITHRVGRLEIMDIAVVIAVSSPHRKVAYEANEYAIERIKRI
HHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEEEEEECCCCCEEEECHHHHHHHHHHHH
VPIWKKEFWDDGTMWIGDQLENTPYPEGKPKKEE
HHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GQVLFEIVDIPIVVEEVTNKVARREAGAITTFIGTVRELTKGKRTLHLEYEAYKPMAVK
CHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHH
QLTRIGEEINEKWPDAKVAITHRVGRLEIMDIAVVIAVSSPHRKVAYEANEYAIERIKRI
HHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEEEEEECCCCCEEEECHHHHHHHHHHHH
VPIWKKEFWDDGTMWIGDQLENTPYPEGKPKKEE
HHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]