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The map label for this gene is acoC [H]

Identifier: 218903894

GI number: 218903894

Start: 2645527

End: 2645877

Strand: Reverse

Name: acoC [H]

Synonym: BCAH820_2778

Alternate gene names: 218903894

Gene position: 2645877-2645527 (Counterclockwise)

Preceding gene: 218903895

Following gene: 218903893

Centisome position: 49.9

GC content: 40.17

Gene sequence:

>351_bases
ATGGCTGTAGAAGTTGTAATGCCGAAGTTAGGGATGGCGATGAAAGAGGGTATTATTACGAGCTGGAATATTAAAGCGGG
TGATAATGTGGCAAAAGGAGAATTAATTGCCAGTATTAACTCGGAAAAAATTGAAACGGAAATAGAAGCACCAGCTGATG
GAACTGTTCTTGATATAGCTGTAAGTGAAGATGAGGGGGTTCCACCTGGCACTGTAATTTGCTACATTGGTAAACCGAAT
GAAAAAGTAGAGGTACATGAAAGCACAAAGGTTGAGGAAGAACTGACAGCGAGTGAAGTAACACAAAAATGTACAACATC
CAGAACCGTTAGGGAAAGAAGTTACGAATAA

Upstream 100 bases:

>100_bases
TTTACCAACGCCGGAGAAAGTAATTGAAACTGTATCAGAAATGATCGGAGACCAATCTTTATTACATGTGTAATGAAACG
ATGAGAAGGGAGAGAGAAAT

Downstream 100 bases:

>100_bases
ACAAAGAATCAAAATATCTCCTGTAGCGAAGAAGATTGCGAAAACTGAAAATCTTGATATTAAATCATTACTTGGTACCG
GTCCAGGTGGAAGAATTACA

Product: putative acetoin dehydrogenase complex, dihydrolipoyllysine-residue acetyltransferase component

Products: NA

Alternate protein names: Acetoin dehydrogenase E2 component; Dihydrolipoamide acetyltransferase component of acetoin cleaving system [H]

Number of amino acids: Translated: 116; Mature: 115

Protein sequence:

>116_residues
MAVEVVMPKLGMAMKEGIITSWNIKAGDNVAKGELIASINSEKIETEIEAPADGTVLDIAVSEDEGVPPGTVICYIGKPN
EKVEVHESTKVEEELTASEVTQKCTTSRTVRERSYE

Sequences:

>Translated_116_residues
MAVEVVMPKLGMAMKEGIITSWNIKAGDNVAKGELIASINSEKIETEIEAPADGTVLDIAVSEDEGVPPGTVICYIGKPN
EKVEVHESTKVEEELTASEVTQKCTTSRTVRERSYE
>Mature_115_residues
AVEVVMPKLGMAMKEGIITSWNIKAGDNVAKGELIASINSEKIETEIEAPADGTVLDIAVSEDEGVPPGTVICYIGKPNE
KVEVHESTKVEEELTASEVTQKCTTSRTVRERSYE

Specific function: The 2-Oxoglutarate Dehydrogenase Complex Catalyzes The Overall Conversion Of 2-Oxoglutarate To Succinyl-CoA And Co(2). It Contains Multiple Copies Of Three Enzymatic Components: 2- Oxoglutarate Dehydrogenase (E1), Dihydrolipoamide Succinyltransferase (E2)

COG id: COG0508

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 lipoyl-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 3096 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001078
- InterPro:   IPR000089
- InterPro:   IPR023213
- InterPro:   IPR004167
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00198 2-oxoacid_dh; PF00364 Biotin_lipoyl; PF02817 E3_binding [H]

EC number: =2.3.1.12 [H]

Molecular weight: Translated: 12552; Mature: 12421

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVEVVMPKLGMAMKEGIITSWNIKAGDNVAKGELIASINSEKIETEIEAPADGTVLDIA
CCEEEECCHHCHHHHCCEEEEEECCCCCCCCCCEEEEECCCCCEEEEECCCCCCCEEEEE
VSEDEGVPPGTVICYIGKPNEKVEVHESTKVEEELTASEVTQKCTTSRTVRERSYE
ECCCCCCCCCEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AVEVVMPKLGMAMKEGIITSWNIKAGDNVAKGELIASINSEKIETEIEAPADGTVLDIA
CEEEECCHHCHHHHCCEEEEEECCCCCCCCCCEEEEECCCCCEEEEECCCCCCCEEEEE
VSEDEGVPPGTVICYIGKPNEKVEVHESTKVEEELTASEVTQKCTTSRTVRERSYE
ECCCCCCCCCEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]