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The map label for this gene is fba1 [H]

Identifier: 218903648

GI number: 218903648

Start: 2404843

End: 2405688

Strand: Direct

Name: fba1 [H]

Synonym: BCAH820_2532

Alternate gene names: 218903648

Gene position: 2404843-2405688 (Clockwise)

Preceding gene: 218903647

Following gene: 218903649

Centisome position: 45.35

GC content: 39.36

Gene sequence:

>846_bases
ATGCCATTAGTTCAAATGAAAGAAATTTTAATAAAAGCAAATCAAGAGAATTATGGGGTTGGGGCTTTCAGTGTCGCGAA
TATGGAAATGGTCATGGGAGCTATCAAAGCAGCTGAAGAGTTAAATTCACCGCTTATTCTACAAATTGCGGAAGTTCGTT
TGAATCATTCGCCAATTCATATGATTGGTCCTTTGATGGTAGCTGCAGCGAAACAAGCAACTGTTCCAGTAGCAGTGCAC
TTTGATCACGGTATGACATTTGAAAAGATTCAAGAGACGTTAGAGATTGGTTTTAGTTCGGTTATGTTTGATGGCTCGCA
CTATCCGTTAGAAGAAAATATACAAAAGACTAAAGAAATTGTAGAACTTGCGAAACAGTACGGTGCGACGGTAGAGGCTG
AGATTGGCAGAGTTGGTGGTAGTGAGGACGGATCAGAAGATATTGAGATGTTGCTGACAAGCACTACAGAAGCAAAACGA
TTTGCAGAAGAAACAGACGTAGATGCTTTAGCTGTTGCAATTGGAAATGCGCATGGTATGTACAATGGAGATCCTAATTT
ACGATTAGACCGCCTACAAGAGATTAATGATGTAGTCCATATCCCACTCGTTTTACATGGCGGCTCTGGCATTAGTCCAG
AGGATTTCAAGCAATGTATTCAACATGGTGTTCGTAAAATTAATGTAGCAACAGCCACATTTCAGAATGTAATTACTGCG
GTTAACAATACCGTCCTAAATACTCCGTATTCAGATTATTTTACGTATCACCAGGATGTTATTAAGGCCGCATATGAAAA
CGTTAAAAGTCATATGCAAATATTCGGAAGTGAAAACAGAGCATAA

Upstream 100 bases:

>100_bases
AATGATTGGGCAATCAGCAGGTCTTCTTACAAAAGGAGTAAAAAGACGAGAAGGTTTGTTTTACATTTAATAAATAATTA
TTGAAATAGGTGAGTATGTA

Downstream 100 bases:

>100_bases
TCAGAAAAATTTTCTTCATTACTAGTTAGAAGAAATTCGGAATGTAGTTAGCTGACAAAAGTGGAGAATGCTAGTGAAGC
CATTAATTAAAAGGAGGAGA

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MPLVQMKEILIKANQENYGVGAFSVANMEMVMGAIKAAEELNSPLILQIAEVRLNHSPIHMIGPLMVAAAKQATVPVAVH
FDHGMTFEKIQETLEIGFSSVMFDGSHYPLEENIQKTKEIVELAKQYGATVEAEIGRVGGSEDGSEDIEMLLTSTTEAKR
FAEETDVDALAVAIGNAHGMYNGDPNLRLDRLQEINDVVHIPLVLHGGSGISPEDFKQCIQHGVRKINVATATFQNVITA
VNNTVLNTPYSDYFTYHQDVIKAAYENVKSHMQIFGSENRA

Sequences:

>Translated_281_residues
MPLVQMKEILIKANQENYGVGAFSVANMEMVMGAIKAAEELNSPLILQIAEVRLNHSPIHMIGPLMVAAAKQATVPVAVH
FDHGMTFEKIQETLEIGFSSVMFDGSHYPLEENIQKTKEIVELAKQYGATVEAEIGRVGGSEDGSEDIEMLLTSTTEAKR
FAEETDVDALAVAIGNAHGMYNGDPNLRLDRLQEINDVVHIPLVLHGGSGISPEDFKQCIQHGVRKINVATATFQNVITA
VNNTVLNTPYSDYFTYHQDVIKAAYENVKSHMQIFGSENRA
>Mature_280_residues
PLVQMKEILIKANQENYGVGAFSVANMEMVMGAIKAAEELNSPLILQIAEVRLNHSPIHMIGPLMVAAAKQATVPVAVHF
DHGMTFEKIQETLEIGFSSVMFDGSHYPLEENIQKTKEIVELAKQYGATVEAEIGRVGGSEDGSEDIEMLLTSTTEAKRF
AEETDVDALAVAIGNAHGMYNGDPNLRLDRLQEINDVVHIPLVLHGGSGISPEDFKQCIQHGVRKINVATATFQNVITAV
NNTVLNTPYSDYFTYHQDVIKAAYENVKSHMQIFGSENRA

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI87082041, Length=284, Percent_Identity=37.3239436619718, Blast_Score=186, Evalue=1e-48,
Organism=Escherichia coli, GI1789526, Length=283, Percent_Identity=37.4558303886926, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1788072, Length=270, Percent_Identity=38.1481481481481, Blast_Score=177, Evalue=6e-46,
Organism=Escherichia coli, GI1789293, Length=209, Percent_Identity=28.2296650717703, Blast_Score=70, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322790, Length=292, Percent_Identity=27.0547945205479, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011289
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 30840; Mature: 30709

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLVQMKEILIKANQENYGVGAFSVANMEMVMGAIKAAEELNSPLILQIAEVRLNHSPIH
CCHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCEEEEEEEHHCCCCCHH
MIGPLMVAAAKQATVPVAVHFDHGMTFEKIQETLEIGFSSVMFDGSHYPLEENIQKTKEI
HHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCHHHEEECCCCCCHHHHHHHHHHH
VELAKQYGATVEAEIGRVGGSEDGSEDIEMLLTSTTEAKRFAEETDVDALAVAIGNAHGM
HHHHHHHCCEEEEHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCHHHEEHEECCCCCC
YNGDPNLRLDRLQEINDVVHIPLVLHGGSGISPEDFKQCIQHGVRKINVATATFQNVITA
CCCCCCCHHHHHHHHHHHEEEEEEEECCCCCCHHHHHHHHHHHHHEEHHHHHHHHHHHHH
VNNTVLNTPYSDYFTYHQDVIKAAYENVKSHMQIFGSENRA
HCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PLVQMKEILIKANQENYGVGAFSVANMEMVMGAIKAAEELNSPLILQIAEVRLNHSPIH
CHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCEEEEEEEHHCCCCCHH
MIGPLMVAAAKQATVPVAVHFDHGMTFEKIQETLEIGFSSVMFDGSHYPLEENIQKTKEI
HHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCHHHEEECCCCCCHHHHHHHHHHH
VELAKQYGATVEAEIGRVGGSEDGSEDIEMLLTSTTEAKRFAEETDVDALAVAIGNAHGM
HHHHHHHCCEEEEHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCHHHEEHEECCCCCC
YNGDPNLRLDRLQEINDVVHIPLVLHGGSGISPEDFKQCIQHGVRKINVATATFQNVITA
CCCCCCCHHHHHHHHHHHEEEEEEEECCCCCCHHHHHHHHHHHHHEEHHHHHHHHHHHHH
VNNTVLNTPYSDYFTYHQDVIKAAYENVKSHMQIFGSENRA
HCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA