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The map label for this gene is iolB [H]

Identifier: 218903649

GI number: 218903649

Start: 2405794

End: 2406585

Strand: Direct

Name: iolB [H]

Synonym: BCAH820_2533

Alternate gene names: 218903649

Gene position: 2405794-2406585 (Clockwise)

Preceding gene: 218903648

Following gene: 218903651

Centisome position: 45.37

GC content: 38.64

Gene sequence:

>792_bases
ATGTTAGGAAAATTGGGTGAATTAAATGAGGGGTATAATGTATTAACAGAAATGAACGGTCAATGCAGTGATATGTTAAT
GGATATAGGCATATATAAGATGACTAATGGGAAAGAAGAGTTGCTATTTGATAATAAGAATGAAACAGCAGTTCTTTTAC
TGGAAGGCGCAATACGTTTAGAGTGGGAAGGCATGGAACAAGTTATTCAAAGACAGTCTGTGTTTGAAGAAAACCCTTGG
TGCTTACATGTATCTAAAAATGTGAAGGTTACCATTACTGCGCTTTCAGATAGTGAAGTGCTTGTTCAAAAAACGGATAA
TGATCAAGAATTTGCTTCTAAGTTATATACTCCAAATGAGTGTCAAAGTGTTGTAGCTGGAGATGGAGTATGGGAGGGAA
CGGCGCAGCGTGTTATTCGTACGATTTTTGACTATAACAATGCAGCATATTCTAATATGGTAGTAGGAGAAGTTATTTCT
TATCCAGGGCGATGGTCCAGTTATCCACCTCATCACCATGATCAACCGGAGGTATATTATTATCGCTTTAACAAACCACA
GGGATTTGGTTGTGCAATGGTTGGTGAGGATGCATATCGCGTTGTACATAATAGCTTTATTACAATTCCAGGTGAGCTAG
ACCATCCACAAGCAACCGCGCCAGGATATGCCATGTATTTTTGTTGGATGATTCGACACTTTGAGAATAATCCTTGGAAT
GATCGTATCATGGAGGAAGAACACAAGTGGTTATTAGAACCAAACGCGAAAATTTGGCCAGAAAAGGAATAG

Upstream 100 bases:

>100_bases
AAAATTTTCTTCATTACTAGTTAGAAGAAATTCGGAATGTAGTTAGCTGACAAAAGTGGAGAATGCTAGTGAAGCCATTA
ATTAAAAGGAGGAGAAAGCC

Downstream 100 bases:

>100_bases
ACGAAAATAAAAACGAGCAATCCTATTCATAGTGATAAGGTGCTCGTTTTGCTATTTGTAGGCAGAAAGAAAAATTCCTC
ATACTGTTATCGCCAGATTA

Product: putative iolB protein

Products: NA

Alternate protein names: 5DG isomerase [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MLGKLGELNEGYNVLTEMNGQCSDMLMDIGIYKMTNGKEELLFDNKNETAVLLLEGAIRLEWEGMEQVIQRQSVFEENPW
CLHVSKNVKVTITALSDSEVLVQKTDNDQEFASKLYTPNECQSVVAGDGVWEGTAQRVIRTIFDYNNAAYSNMVVGEVIS
YPGRWSSYPPHHHDQPEVYYYRFNKPQGFGCAMVGEDAYRVVHNSFITIPGELDHPQATAPGYAMYFCWMIRHFENNPWN
DRIMEEEHKWLLEPNAKIWPEKE

Sequences:

>Translated_263_residues
MLGKLGELNEGYNVLTEMNGQCSDMLMDIGIYKMTNGKEELLFDNKNETAVLLLEGAIRLEWEGMEQVIQRQSVFEENPW
CLHVSKNVKVTITALSDSEVLVQKTDNDQEFASKLYTPNECQSVVAGDGVWEGTAQRVIRTIFDYNNAAYSNMVVGEVIS
YPGRWSSYPPHHHDQPEVYYYRFNKPQGFGCAMVGEDAYRVVHNSFITIPGELDHPQATAPGYAMYFCWMIRHFENNPWN
DRIMEEEHKWLLEPNAKIWPEKE
>Mature_263_residues
MLGKLGELNEGYNVLTEMNGQCSDMLMDIGIYKMTNGKEELLFDNKNETAVLLLEGAIRLEWEGMEQVIQRQSVFEENPW
CLHVSKNVKVTITALSDSEVLVQKTDNDQEFASKLYTPNECQSVVAGDGVWEGTAQRVIRTIFDYNNAAYSNMVVGEVIS
YPGRWSSYPPHHHDQPEVYYYRFNKPQGFGCAMVGEDAYRVVHNSFITIPGELDHPQATAPGYAMYFCWMIRHFENNPWN
DRIMEEEHKWLLEPNAKIWPEKE

Specific function: Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate) [H]

COG id: COG3718

COG function: function code G; Uncharacterized enzyme involved in inositol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isomerase iolB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR021120
- InterPro:   IPR014710 [H]

Pfam domain/function: PF04962 KduI [H]

EC number: NA

Molecular weight: Translated: 30330; Mature: 30330

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGKLGELNEGYNVLTEMNGQCSDMLMDIGIYKMTNGKEELLFDNKNETAVLLLEGAIRL
CCCCCCCCCCCCHHHHHCCCCHHHHHHHCCEEEECCCCHHEEEECCCCEEEEEEECCEEE
EWEGMEQVIQRQSVFEENPWCLHVSKNVKVTITALSDSEVLVQKTDNDQEFASKLYTPNE
EECHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEECCCEEEEEECCCHHHHHHHCCCCHH
CQSVVAGDGVWEGTAQRVIRTIFDYNNAAYSNMVVGEVISYPGRWSSYPPHHHDQPEVYY
HHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEE
YRFNKPQGFGCAMVGEDAYRVVHNSFITIPGELDHPQATAPGYAMYFCWMIRHFENNPWN
EEECCCCCCEEEEECCHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
DRIMEEEHKWLLEPNAKIWPEKE
CHHHCCCCCEEECCCCCCCCCCC
>Mature Secondary Structure
MLGKLGELNEGYNVLTEMNGQCSDMLMDIGIYKMTNGKEELLFDNKNETAVLLLEGAIRL
CCCCCCCCCCCCHHHHHCCCCHHHHHHHCCEEEECCCCHHEEEECCCCEEEEEEECCEEE
EWEGMEQVIQRQSVFEENPWCLHVSKNVKVTITALSDSEVLVQKTDNDQEFASKLYTPNE
EECHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEECCCEEEEEECCCHHHHHHHCCCCHH
CQSVVAGDGVWEGTAQRVIRTIFDYNNAAYSNMVVGEVISYPGRWSSYPPHHHDQPEVYY
HHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEE
YRFNKPQGFGCAMVGEDAYRVVHNSFITIPGELDHPQATAPGYAMYFCWMIRHFENNPWN
EEECCCCCCEEEEECCHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
DRIMEEEHKWLLEPNAKIWPEKE
CHHHCCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA