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The map label for this gene is bla1 [H]

Identifier: 218903638

GI number: 218903638

Start: 2393340

End: 2394260

Strand: Direct

Name: bla1 [H]

Synonym: BCAH820_2522

Alternate gene names: 218903638

Gene position: 2393340-2394260 (Clockwise)

Preceding gene: 218903637

Following gene: 218903640

Centisome position: 45.13

GC content: 39.02

Gene sequence:

>921_bases
TTGAAAAACAAGAAAATGCTAAAAATAGGGATGTGTGTTGGTATATTAGGTTTAAGTATTACAAGCATAGAAGCTTTTAC
AGGAGGACCATTGCAAGTTGAAGCGAAAGAAAAGACTGGACAAGTGAAACATAAAAATCAGGCGACGCATAAAGAGTTCT
CTCAACTTGAGAAAAAATTTGATGCTCGATTAGGTGTATATGCGATTGATACTGGTACAAATCAAACAATCGCTTATCGA
CCTAACGAAAGGTTTGCCTTTGCATCAACTTACAAGGCTTTAGCGGCAGGGGTATTACTGCAACAGAACTCTACTAAGAA
ATTAGATGAAGTTATTACTTATACGAAAGAAGACTTAGTGGATTATTCACCTGTTACAGAGAAACATGTAGATACTGGAA
TGACACTAGGAGAAATTGCGGAGGCTGCTGTTCGTTACAGTGATAATACTGCAGGGAACATTTTATTTCATAAAATAGGC
GGACCGAAAGGATATGAAAAAGCGCTTAGAAAGATGGGGGACCGGGTTACTATGTCTGATCGCTTTGAAACAGAATTAAA
CGAGGCTATTCCAGGAGACATTCGTGATACTAGTACAGCAAMAGCAATTGCTAGGAATCTTAAAGCTTTTACGGCCGGAA
ATGCGCTTCCAAATCATAAACGTAACATTCTTACAGAGTGGATGAAAGGAAATGCTACAGGAGACAAACTTATTCGTGCA
GGCGTGCCAACTGATTGGGTAGTTGCAGATAAATCAGGAGCTGGAAGTTACGGGACAAGAAATGATATTGCTATCGTTTG
GCCGCCAAATAGAGCACCTATTATCATCGCAATTTTATCTAGTAAAGATGAAAAAGGGGCTACCTATGATAATCAACTCA
TTGCAGAGGCGGCTGAAGTTATAGTTAATGCTTTTAGGTGA

Upstream 100 bases:

>100_bases
GCGATAAAAATTTTTAAGTTTATGGAACAAATTTGTTTCGGTGATTGTCTATTATGTGTACGTATAAAAAGGTATTAAGT
ATTTGAAAGGAATGATAGTT

Downstream 100 bases:

>100_bases
TAATCTCTCAATTCTTTATGTAATGTAATTGAAAATATGAACTTGGAAAGCGATTCTTTTTAATATGAAAAGAATCGCTT
TTTTTGTATTCCTAATACAT

Product: beta-lactamase Bla1

Products: NA

Alternate protein names: Beta-lactamase I; Penicillinase [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MKNKKMLKIGMCVGILGLSITSIEAFTGGPLQVEAKEKTGQVKHKNQATHKEFSQLEKKFDARLGVYAIDTGTNQTIAYR
PNERFAFASTYKALAAGVLLQQNSTKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIG
GPKGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAXAIARNLKAFTAGNALPNHKRNILTEWMKGNATGDKLIRA
GVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSKDEKGATYDNQLIAEAAEVIVNAFR

Sequences:

>Translated_306_residues
MKNKKMLKIGMCVGILGLSITSIEAFTGGPLQVEAKEKTGQVKHKNQATHKEFSQLEKKFDARLGVYAIDTGTNQTIAYR
PNERFAFASTYKALAAGVLLQQNSTKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIG
GPKGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAXAIARNLKAFTAGNALPNHKRNILTEWMKGNATGDKLIRA
GVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSKDEKGATYDNQLIAEAAEVIVNAFR
>Mature_306_residues
MKNKKMLKIGMCVGILGLSITSIEAFTGGPLQVEAKEKTGQVKHKNQATHKEFSQLEKKFDARLGVYAIDTGTNQTIAYR
PNERFAFASTYKALAAGVLLQQNSTKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIG
GPKGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAXAIARNLKAFTAGNALPNHKRNILTEWMKGNATGDKLIRA
GVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSKDEKGATYDNQLIAEAAEVIVNAFR

Specific function: Acts preferentially on penicillins [H]

COG id: COG2367

COG function: function code V; Beta-lactamase class A

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-A beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466
- InterPro:   IPR000871 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 33365; Mature: 33365

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS00146 BETA_LACTAMASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKKMLKIGMCVGILGLSITSIEAFTGGPLQVEAKEKTGQVKHKNQATHKEFSQLEKKF
CCCCCEEEHHHHHHHHHHHHEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
DARLGVYAIDTGTNQTIAYRPNERFAFASTYKALAAGVLLQQNSTKKLDEVITYTKEDLV
HCCCCEEEEECCCCCEEEECCCCCEEHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHC
DYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGPKGYEKALRKMGDRVTMSD
CCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCEECH
RFETELNEAIPGDIRDTSTAXAIARNLKAFTAGNALPNHKRNILTEWMKGNATGDKLIRA
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHEEC
GVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSKDEKGATYDNQLIAEAAEV
CCCCCEEEECCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
IVNAFR
HHHHCC
>Mature Secondary Structure
MKNKKMLKIGMCVGILGLSITSIEAFTGGPLQVEAKEKTGQVKHKNQATHKEFSQLEKKF
CCCCCEEEHHHHHHHHHHHHEEEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
DARLGVYAIDTGTNQTIAYRPNERFAFASTYKALAAGVLLQQNSTKKLDEVITYTKEDLV
HCCCCEEEEECCCCCEEEECCCCCEEHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHC
DYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGPKGYEKALRKMGDRVTMSD
CCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCEECH
RFETELNEAIPGDIRDTSTAXAIARNLKAFTAGNALPNHKRNILTEWMKGNATGDKLIRA
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHEEC
GVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSKDEKGATYDNQLIAEAAEV
CCCCCEEEECCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
IVNAFR
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2991192 [H]