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The map label for this gene is yqgF [H]

Identifier: 218903637

GI number: 218903637

Start: 2390970

End: 2393102

Strand: Direct

Name: yqgF [H]

Synonym: BCAH820_2521

Alternate gene names: 218903637

Gene position: 2390970-2393102 (Clockwise)

Preceding gene: 218903636

Following gene: 218903638

Centisome position: 45.09

GC content: 34.74

Gene sequence:

>2133_bases
ATGAAAGAACAAAAAGGAAAGAAGCAGAAGACATATATATCTATTCGATTAAATATAATGTTCCTTTGTATATTTTTACT
ATTCTCAGCTATTATTATGCAGCTAGGAAAAGTACAAATCGTTGAGGGAGAGGCTTATAAGAATCAAGTGGAAAACAGTC
AAAATGCAACAACTAGCATACCAGTTCCGCGTGGACAAATTTTAGATCGAGAAGGGAAAACGGTCGTTAATAATAAGTCT
CTTCGTACAATTACGTATACAAGGGTGAAGGGGATTACGAGTGACGATATTTTAAAAACAGCAAAAGACTTGGCGAAAGT
ACTTGAAATGCCTGAACAAGATATTATTAAATTAACTGATATCGATAAAAAAGATTTTTGGATGCAGTTGAATACGAAAC
GTGCGGATACAAAGATTACTAAAAAAGATATAGAAAAGTTTAAAGAAAAGGGAATAGAGGGAAAAGAGTTAGATAAAAAA
ATAGAAGATTTAAGACGAAGTCGCGTTACAGAAGTAGAATTGGGTGAATTAACAGAACAAGATTTAAAGGTGTTAGCTAT
TAAAAGTAAAATGAGTTCAGGTTATCAACTAACACCACAAATTATTAAAAAAGATGTAACAGATGAGGAGTATGCACGGA
TAAGTGAAAATCTTGCGAATTTTCCAGGAGTAGATGCAACGGTTGATTGGGAACGTAATTATGTAAATAGTAATTTGTTT
CGTTCCGTATTAGGTAATATTACGAGTAGTGAAGAAGGTCTGCCGAAAGAAAACTTAGATTCTTATTTGGTACGCGGATA
TAACCGTAATGACCGTGTCGGAAAAAGTTATATTGAACAACGATATGAAGATGTATTACATGGCACAAAAGAAGAAGTGA
AAAACATTACTGATAAATCAGGAAACATTATAAATACAGAAGTAATCGCTAAAGGAAAAAGTGGTAAAAGTTTAACATTA
ACGATTGATATGGAATTACAAAAGAAAGTGGAAGAAAGTATAGAGAAAAACTTGAGAGCTTTTAAGAGTTCAGAGCCGCT
ACTCGATCGAGCTTTTGTCGTCATGACGAATCCAAATAACGGACAGATTTTATCTATGGCAGGCAAAAAGATTGTAGAAA
AAGAAGGAGTACTAGAGATTGAGGATTTGGCATTAGGCAATATGACAACTTCGTATGAGCTAGGCTCTGCTGTAAAAGGT
GCTACTTTATTAACTGGATATGAGACAGGAGCAATACATCCAGGAGATCAATTTTATGATGCACCGATGAAATTTAAAGG
TACACAAGCAAAGAAATCGTGGAATGTATCTGGATTTGGTAATATTAATGATTTACGAGCTTTACAAGTATCTTCGAATG
TATACATGTTCCAGACAGCTTTAAAAATTGCGGGAGTTAATTACGTACCAAATGGCTCATTGGATATTAAACAAGGAGCA
TTTGATACGATGCGCTATTATTTCAAGCAATTTGGTTTAGGCGTCCCAACAGGTATCGATTTACCGAATGAAATAATTGG
ACAAACGAGAAAAGTAGATAGTCAACCTGGATTTTTACTAGACTTTTCCATCGGTCAGTATGATACGTATACGCCGTTGC
AATTAGCTCAATATATTTCAACGATTGCGAATGGTGGTTATAGAATGCAACCTCAAATTGTACAAGAAATACGAGAACAA
TCAATTAAAGAAGAGGTTGGTAAAGTTATTCGCTCTATAGAGCCTGTAGTATTAAATCGGATTGATATGAAGACAGAATA
TATTGATCGAATAAAAGAAGGGTTTAGATGGGTATTCCAAGAAGGGGATGGAACTGGCGTAAAGCATTTCAAAAATGCTC
CATATAAACCAGCAGGAAAGACAGGGACAGCCCAAACTGTGTATGGTGGAGATGATCCAATTGGTAGAAATGCAAAAGGA
GAACGTATGGAATGTTACAACTTAACGTTAGTTGGATATGCTCCATATGATAATCCAGAAGTAGCGTTTTCTGTAGTAGT
CCCATGGCTTCATAATGATAAAAGTGGAATTAATTCTATAATCGGAAAGGAAGTTTTAGATGTATACTTTGATTTGAAAA
AGCAGCGTATGCATGATGAAGCTGCTAGTACAGATACTTCGAATCAAAATTAG

Upstream 100 bases:

>100_bases
AAAAAGATAAGACACTATTTATAACCGAATAATGGTTTGTAATATATAGGGAACGTTTAAGTATTAGTGAGAAGTTCCAG
AAGAATTATATGGAGGATTT

Downstream 100 bases:

>100_bases
TAAAATTTGTGTACTTTTCTCAGGGAAGAACCCCCTGTTTGTATAAAGGCATTTATAAGTAAAAAGATGAAATGTGAAAT
AAGAGATAGCAGCGGTCATA

Product: penicillin-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 710; Mature: 710

Protein sequence:

>710_residues
MKEQKGKKQKTYISIRLNIMFLCIFLLFSAIIMQLGKVQIVEGEAYKNQVENSQNATTSIPVPRGQILDREGKTVVNNKS
LRTITYTRVKGITSDDILKTAKDLAKVLEMPEQDIIKLTDIDKKDFWMQLNTKRADTKITKKDIEKFKEKGIEGKELDKK
IEDLRRSRVTEVELGELTEQDLKVLAIKSKMSSGYQLTPQIIKKDVTDEEYARISENLANFPGVDATVDWERNYVNSNLF
RSVLGNITSSEEGLPKENLDSYLVRGYNRNDRVGKSYIEQRYEDVLHGTKEEVKNITDKSGNIINTEVIAKGKSGKSLTL
TIDMELQKKVEESIEKNLRAFKSSEPLLDRAFVVMTNPNNGQILSMAGKKIVEKEGVLEIEDLALGNMTTSYELGSAVKG
ATLLTGYETGAIHPGDQFYDAPMKFKGTQAKKSWNVSGFGNINDLRALQVSSNVYMFQTALKIAGVNYVPNGSLDIKQGA
FDTMRYYFKQFGLGVPTGIDLPNEIIGQTRKVDSQPGFLLDFSIGQYDTYTPLQLAQYISTIANGGYRMQPQIVQEIREQ
SIKEEVGKVIRSIEPVVLNRIDMKTEYIDRIKEGFRWVFQEGDGTGVKHFKNAPYKPAGKTGTAQTVYGGDDPIGRNAKG
ERMECYNLTLVGYAPYDNPEVAFSVVVPWLHNDKSGINSIIGKEVLDVYFDLKKQRMHDEAASTDTSNQN

Sequences:

>Translated_710_residues
MKEQKGKKQKTYISIRLNIMFLCIFLLFSAIIMQLGKVQIVEGEAYKNQVENSQNATTSIPVPRGQILDREGKTVVNNKS
LRTITYTRVKGITSDDILKTAKDLAKVLEMPEQDIIKLTDIDKKDFWMQLNTKRADTKITKKDIEKFKEKGIEGKELDKK
IEDLRRSRVTEVELGELTEQDLKVLAIKSKMSSGYQLTPQIIKKDVTDEEYARISENLANFPGVDATVDWERNYVNSNLF
RSVLGNITSSEEGLPKENLDSYLVRGYNRNDRVGKSYIEQRYEDVLHGTKEEVKNITDKSGNIINTEVIAKGKSGKSLTL
TIDMELQKKVEESIEKNLRAFKSSEPLLDRAFVVMTNPNNGQILSMAGKKIVEKEGVLEIEDLALGNMTTSYELGSAVKG
ATLLTGYETGAIHPGDQFYDAPMKFKGTQAKKSWNVSGFGNINDLRALQVSSNVYMFQTALKIAGVNYVPNGSLDIKQGA
FDTMRYYFKQFGLGVPTGIDLPNEIIGQTRKVDSQPGFLLDFSIGQYDTYTPLQLAQYISTIANGGYRMQPQIVQEIREQ
SIKEEVGKVIRSIEPVVLNRIDMKTEYIDRIKEGFRWVFQEGDGTGVKHFKNAPYKPAGKTGTAQTVYGGDDPIGRNAKG
ERMECYNLTLVGYAPYDNPEVAFSVVVPWLHNDKSGINSIIGKEVLDVYFDLKKQRMHDEAASTDTSNQN
>Mature_710_residues
MKEQKGKKQKTYISIRLNIMFLCIFLLFSAIIMQLGKVQIVEGEAYKNQVENSQNATTSIPVPRGQILDREGKTVVNNKS
LRTITYTRVKGITSDDILKTAKDLAKVLEMPEQDIIKLTDIDKKDFWMQLNTKRADTKITKKDIEKFKEKGIEGKELDKK
IEDLRRSRVTEVELGELTEQDLKVLAIKSKMSSGYQLTPQIIKKDVTDEEYARISENLANFPGVDATVDWERNYVNSNLF
RSVLGNITSSEEGLPKENLDSYLVRGYNRNDRVGKSYIEQRYEDVLHGTKEEVKNITDKSGNIINTEVIAKGKSGKSLTL
TIDMELQKKVEESIEKNLRAFKSSEPLLDRAFVVMTNPNNGQILSMAGKKIVEKEGVLEIEDLALGNMTTSYELGSAVKG
ATLLTGYETGAIHPGDQFYDAPMKFKGTQAKKSWNVSGFGNINDLRALQVSSNVYMFQTALKIAGVNYVPNGSLDIKQGA
FDTMRYYFKQFGLGVPTGIDLPNEIIGQTRKVDSQPGFLLDFSIGQYDTYTPLQLAQYISTIANGGYRMQPQIVQEIREQ
SIKEEVGKVIRSIEPVVLNRIDMKTEYIDRIKEGFRWVFQEGDGTGVKHFKNAPYKPAGKTGTAQTVYGGDDPIGRNAKG
ERMECYNLTLVGYAPYDNPEVAFSVVVPWLHNDKSGINSIIGKEVLDVYFDLKKQRMHDEAASTDTSNQN

Specific function: Cell Wall Formation; Pbp-2 Is Responsible For The Determination Of The Rod Shape Of The Cell. Its Synthesize Cross- Linked Peptidoglycan From The Lipid Intermediates. [C]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786854, Length=530, Percent_Identity=24.9056603773585, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1786272, Length=427, Percent_Identity=25.9953161592506, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005311
- InterPro:   IPR001460 [H]

Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 79854; Mature: 79854

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEQKGKKQKTYISIRLNIMFLCIFLLFSAIIMQLGKVQIVEGEAYKNQVENSQNATTSI
CCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHCCCCCCCEEC
PVPRGQILDREGKTVVNNKSLRTITYTRVKGITSDDILKTAKDLAKVLEMPEQDIIKLTD
CCCCCCEECCCCCEEECCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHCEEEEC
IDKKDFWMQLNTKRADTKITKKDIEKFKEKGIEGKELDKKIEDLRRSRVTEVELGELTEQ
CCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHCHH
DLKVLAIKSKMSSGYQLTPQIIKKDVTDEEYARISENLANFPGVDATVDWERNYVNSNLF
HHHEEEEHHHHCCCCEECHHHHHHCCCHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHH
RSVLGNITSSEEGLPKENLDSYLVRGYNRNDRVGKSYIEQRYEDVLHGTKEEVKNITDKS
HHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
GNIINTEVIAKGKSGKSLTLTIDMELQKKVEESIEKNLRAFKSSEPLLDRAFVVMTNPNN
CCEEEEEEEEECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
GQILSMAGKKIVEKEGVLEIEDLALGNMTTSYELGSAVKGATLLTGYETGAIHPGDQFYD
CEEEEECCHHHHHHCCCEEEEHEEECCCCCCHHHCCCCCCCEEEECCCCCCCCCCCHHCC
APMKFKGTQAKKSWNVSGFGNINDLRALQVSSNVYMFQTALKIAGVNYVPNGSLDIKQGA
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEHHHHHHHHCCCCCCCCCCCCCCCH
FDTMRYYFKQFGLGVPTGIDLPNEIIGQTRKVDSQPGFLLDFSIGQYDTYTPLQLAQYIS
HHHHHHHHHHHCCCCCCCCCCCHHHHCCHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHH
TIANGGYRMQPQIVQEIREQSIKEEVGKVIRSIEPVVLNRIDMKTEYIDRIKEGFRWVFQ
HHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEEE
EGDGTGVKHFKNAPYKPAGKTGTAQTVYGGDDPIGRNAKGERMECYNLTLVGYAPYDNPE
CCCCCCCHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEEEEEECCCCCCC
VAFSVVVPWLHNDKSGINSIIGKEVLDVYFDLKKQRMHDEAASTDTSNQN
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKEQKGKKQKTYISIRLNIMFLCIFLLFSAIIMQLGKVQIVEGEAYKNQVENSQNATTSI
CCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHCCCCCCCEEC
PVPRGQILDREGKTVVNNKSLRTITYTRVKGITSDDILKTAKDLAKVLEMPEQDIIKLTD
CCCCCCEECCCCCEEECCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHCEEEEC
IDKKDFWMQLNTKRADTKITKKDIEKFKEKGIEGKELDKKIEDLRRSRVTEVELGELTEQ
CCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHCHH
DLKVLAIKSKMSSGYQLTPQIIKKDVTDEEYARISENLANFPGVDATVDWERNYVNSNLF
HHHEEEEHHHHCCCCEECHHHHHHCCCHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHH
RSVLGNITSSEEGLPKENLDSYLVRGYNRNDRVGKSYIEQRYEDVLHGTKEEVKNITDKS
HHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
GNIINTEVIAKGKSGKSLTLTIDMELQKKVEESIEKNLRAFKSSEPLLDRAFVVMTNPNN
CCEEEEEEEEECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
GQILSMAGKKIVEKEGVLEIEDLALGNMTTSYELGSAVKGATLLTGYETGAIHPGDQFYD
CEEEEECCHHHHHHCCCEEEEHEEECCCCCCHHHCCCCCCCEEEECCCCCCCCCCCHHCC
APMKFKGTQAKKSWNVSGFGNINDLRALQVSSNVYMFQTALKIAGVNYVPNGSLDIKQGA
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEHHHHHHHHCCCCCCCCCCCCCCCH
FDTMRYYFKQFGLGVPTGIDLPNEIIGQTRKVDSQPGFLLDFSIGQYDTYTPLQLAQYIS
HHHHHHHHHHHCCCCCCCCCCCHHHHCCHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHH
TIANGGYRMQPQIVQEIREQSIKEEVGKVIRSIEPVVLNRIDMKTEYIDRIKEGFRWVFQ
HHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEEE
EGDGTGVKHFKNAPYKPAGKTGTAQTVYGGDDPIGRNAKGERMECYNLTLVGYAPYDNPE
CCCCCCCHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEEEEEECCCCCCC
VAFSVVVPWLHNDKSGINSIIGKEVLDVYFDLKKQRMHDEAASTDTSNQN
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]