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The map label for this gene is hblA [H]

Identifier: 218903040

GI number: 218903040

Start: 1828209

End: 1829417

Strand: Direct

Name: hblA [H]

Synonym: BCAH820_1923

Alternate gene names: 218903040

Gene position: 1828209-1829417 (Clockwise)

Preceding gene: 218903039

Following gene: 218903041

Centisome position: 34.48

GC content: 36.56

Gene sequence:

>1209_bases
ATGACAAAAAAACCTTATAAAGTAATGGCTCTATCAGCACTTATGGCAGTATTTGCAGCAGGAAACATTATGCCAGCCCA
TACGTATGCAGCTGAAAGTACAGTGAAACAAGCTCCAGTTCATGCGGTAACAAAAGCTTATAATGACTATGAGGAATACT
CATTAGGACCAGAAGGCCTAAAAGATGCAATGGAAAGAACAGGTTCAAACGCTTTAGTAATGGATCTGTACGCTTTAACA
ATTATTAAACAAGGTAATGTTAACTTTGGAAATGTATCGTCTGTTGATGCGGCTTTAAAAGGGAAAGTGATTCAGCACCA
GGATACAGCTAGAGGAAATGCGAAGCAATGGCTAGATGTACTAAAGCCACAGCTTATTTCAACGAATCAAAATATCATTA
ATTACAATACGAAATTCCAAAACTATTACGATACTTTAGTTGCTGCGGTAGATGCAAAAGATAAAGCGACTCTTACGAAA
GGTTTAACTAGATTATCAAGTAGTATTAATGAAAATAAAGCGCAAGTAGATCAGTTAGTAGATGACTTGAAGAAATTCCG
AAATAAAATGACGTCCGATACGCAAAACTTCAAGGGAGACGCAAATCAAATTACATCTATTTTAGCTAGTCAAGATGCAG
GAATCCCGCTTCTGCAAAATCAAATTACAACGTACAATGAAGCAATTAGTAAATATAATGCAATTATTATCGGTTCATCA
GTTGCGACAGCTCTAGGGCCAATTGCCATTATTGGTGGCGCAGTAGTGATTGCTACAGGTGCAGGAACGCCGTTAGGAGT
CGCGTTAATTGCAGGTGGTGCAGCAGCTGTAGGCGGTGGTACAGCTGGTATCGTATTAGCGAAGAAAGAACTTGATAATG
CACAAGCTGAAATTCAAAAAATAACAGGACAAGTTACAACTGCTCAATTAGAAGTAGCTGGGTTAACGAACATTAAGACA
CAAACGGAGTATTTAACAAATACAATTGATACTGCAATTACAGCGTTGCAAAACATTTCAAACCAATGGTACACAATGGG
ATCAAAATACAATTCTTTACTTCAAAATGTAGATTCAATTAGTCCGAATGACCTTGTTTTCATTAAAGAAGATTTAAACA
TTGCGAAAGATAGCTGGAAAAACATTAAAGACTATGCAGAAAAGATTTATGCTGAAGATATTAAAGTAGTAGATACGAAA
AAAGCTTAA

Upstream 100 bases:

>100_bases
GTAAGTGATGAAATGAATAAGCAAACAAATCAATTTGAAGATTACGTTACAAACGTTGAAGTACATTAAAAATAAGTAAC
GATATAGGGAGAGAAGAAAA

Downstream 100 bases:

>100_bases
TCAAATACGAATCGTTAGAGCGTTGCGTATTGATAAAAGATTTGAAGCTCCTGTTCAGTTGTGAGCAGGAGCTTTTTATA
CCCTTATAAAGAAAATAGGT

Product: enterotoxin B

Products: NA

Alternate protein names: Enterotoxin 40 kDa subunit [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MTKKPYKVMALSALMAVFAAGNIMPAHTYAAESTVKQAPVHAVTKAYNDYEEYSLGPEGLKDAMERTGSNALVMDLYALT
IIKQGNVNFGNVSSVDAALKGKVIQHQDTARGNAKQWLDVLKPQLISTNQNIINYNTKFQNYYDTLVAAVDAKDKATLTK
GLTRLSSSINENKAQVDQLVDDLKKFRNKMTSDTQNFKGDANQITSILASQDAGIPLLQNQITTYNEAISKYNAIIIGSS
VATALGPIAIIGGAVVIATGAGTPLGVALIAGGAAAVGGGTAGIVLAKKELDNAQAEIQKITGQVTTAQLEVAGLTNIKT
QTEYLTNTIDTAITALQNISNQWYTMGSKYNSLLQNVDSISPNDLVFIKEDLNIAKDSWKNIKDYAEKIYAEDIKVVDTK
KA

Sequences:

>Translated_402_residues
MTKKPYKVMALSALMAVFAAGNIMPAHTYAAESTVKQAPVHAVTKAYNDYEEYSLGPEGLKDAMERTGSNALVMDLYALT
IIKQGNVNFGNVSSVDAALKGKVIQHQDTARGNAKQWLDVLKPQLISTNQNIINYNTKFQNYYDTLVAAVDAKDKATLTK
GLTRLSSSINENKAQVDQLVDDLKKFRNKMTSDTQNFKGDANQITSILASQDAGIPLLQNQITTYNEAISKYNAIIIGSS
VATALGPIAIIGGAVVIATGAGTPLGVALIAGGAAAVGGGTAGIVLAKKELDNAQAEIQKITGQVTTAQLEVAGLTNIKT
QTEYLTNTIDTAITALQNISNQWYTMGSKYNSLLQNVDSISPNDLVFIKEDLNIAKDSWKNIKDYAEKIYAEDIKVVDTK
KA
>Mature_401_residues
TKKPYKVMALSALMAVFAAGNIMPAHTYAAESTVKQAPVHAVTKAYNDYEEYSLGPEGLKDAMERTGSNALVMDLYALTI
IKQGNVNFGNVSSVDAALKGKVIQHQDTARGNAKQWLDVLKPQLISTNQNIINYNTKFQNYYDTLVAAVDAKDKATLTKG
LTRLSSSINENKAQVDQLVDDLKKFRNKMTSDTQNFKGDANQITSILASQDAGIPLLQNQITTYNEAISKYNAIIIGSSV
ATALGPIAIIGGAVVIATGAGTPLGVALIAGGAAAVGGGTAGIVLAKKELDNAQAEIQKITGQVTTAQLEVAGLTNIKTQ
TEYLTNTIDTAITALQNISNQWYTMGSKYNSLLQNVDSISPNDLVFIKEDLNIAKDSWKNIKDYAEKIYAEDIKVVDTKK
A

Specific function: Cytotoxic protein, part of the enterotoxin complex. Responsible for binding to erythrocytes. This enterotoxin is thought to be the cause of the diarrheal form of gastroenteritis caused by food-borne strains of B.cereus [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cell membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008414
- InterPro:   IPR010356 [H]

Pfam domain/function: PF05791 Bacillus_HBL [H]

EC number: NA

Molecular weight: Translated: 43105; Mature: 42974

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKPYKVMALSALMAVFAAGNIMPAHTYAAESTVKQAPVHAVTKAYNDYEEYSLGPEGL
CCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
KDAMERTGSNALVMDLYALTIIKQGNVNFGNVSSVDAALKGKVIQHQDTARGNAKQWLDV
HHHHHHCCCCEEHHHHHHHHHEECCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHH
LKPQLISTNQNIINYNTKFQNYYDTLVAAVDAKDKATLTKGLTRLSSSINENKAQVDQLV
HCHHHCCCCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
DDLKKFRNKMTSDTQNFKGDANQITSILASQDAGIPLLQNQITTYNEAISKYNAIIIGSS
HHHHHHHHHHCCCCHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEECCH
VATALGPIAIIGGAVVIATGAGTPLGVALIAGGAAAVGGGTAGIVLAKKELDNAQAEIQK
HHHHHHHHHHHCCEEEEEECCCCCHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHH
ITGQVTTAQLEVAGLTNIKTQTEYLTNTIDTAITALQNISNQWYTMGSKYNSLLQNVDSI
HHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCHHHEECHHHHHHHHHHHHCC
SPNDLVFIKEDLNIAKDSWKNIKDYAEKIYAEDIKVVDTKKA
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCC
>Mature Secondary Structure 
TKKPYKVMALSALMAVFAAGNIMPAHTYAAESTVKQAPVHAVTKAYNDYEEYSLGPEGL
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
KDAMERTGSNALVMDLYALTIIKQGNVNFGNVSSVDAALKGKVIQHQDTARGNAKQWLDV
HHHHHHCCCCEEHHHHHHHHHEECCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHH
LKPQLISTNQNIINYNTKFQNYYDTLVAAVDAKDKATLTKGLTRLSSSINENKAQVDQLV
HCHHHCCCCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
DDLKKFRNKMTSDTQNFKGDANQITSILASQDAGIPLLQNQITTYNEAISKYNAIIIGSS
HHHHHHHHHHCCCCHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEECCH
VATALGPIAIIGGAVVIATGAGTPLGVALIAGGAAAVGGGTAGIVLAKKELDNAQAEIQK
HHHHHHHHHHHCCEEEEEECCCCCHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHH
ITGQVTTAQLEVAGLTNIKTQTEYLTNTIDTAITALQNISNQWYTMGSKYNSLLQNVDSI
HHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCHHHEECHHHHHHHHHHHHCC
SPNDLVFIKEDLNIAKDSWKNIKDYAEKIYAEDIKVVDTKKA
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7693651; 8319899 [H]