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The map label for this gene is hblA [H]

Identifier: 218903041

GI number: 218903041

Start: 1829525

End: 1830604

Strand: Direct

Name: hblA [H]

Synonym: BCAH820_1924

Alternate gene names: 218903041

Gene position: 1829525-1830604 (Clockwise)

Preceding gene: 218903040

Following gene: 218903042

Centisome position: 34.5

GC content: 33.98

Gene sequence:

>1080_bases
ATGCAGAAACGATTTTATAAAAAATGTCTTTTAACGTTAATGATTGCTGGGGTGGCAACGAGTAATGCATTTCCTTTACA
TCCTTTTGCAGCAGAACAAAATGTAAAAACATTGCAAGAAAGTGCGAAAAATTATTCGTTAGGGCCAGCTGGATTCCAAG
ATGTAATGGCGCAAACGACATCGAGCATATTCGCAATGGATTCATATGCAAAATTAATTCAAAATCAACAAGAGACTGAT
TTAAGTAAAATAAGTTCCATTAATAGTGAGTTTAAAGGAAATATGATGCAGCACCAACGAGATGCAAAAATTAACGCGGC
GTATTGGTTAGATCGTATGAAGCCGCAAATTATGAAAACGGATCAAAATATTATTAATTACAATAATACTTTTCAAGCGT
ATTATAATAGCATGCTAATTGCGATTGATCAAAAAGATAGCGTAAAGTTGAAAGCGGATTTAGAAAAATTGTATGCGGAT
ATTGTAAAGAATCAAAATGAGGTAGATGTATTATTAGGAGATTTGAAAACCTTTCGTGATAGAATGGCGAAAGATACAAA
TAGCTTTAAAGAGGATACAAATCGTCTAACCTCGATTTTGGCAAGTACGAATGCTGGAATCCCCGCTCTAGAGCAACAAA
TTAATACATATAATGATTCAATCAAAAAGAGTAATGATATGGTCATTGCTGGTGGTGTACTTTGCGTAGCGTTAATAACA
TGTCTTGCTGGCGGACCTATGATTGCCGTTGCGAAAAAAGATATTGCAAATGCAGAACGAGAAATCGCTAATTTAAAAGA
TAGAATTTCTGGAGCGCAAGCAGAAGTCGCAATTTTGACAGATGTAAAAAATAAAACAACAAATATGACTGAAACGATTG
ATGCAGCAATTACAGCACTGCAAAACATTTCAAATCAATGGTATACAGTAGGGGCAAAGTATAATAATTTACTACAAAAC
GTAAAAGGAATTAGCCCTGAAGAATTTACGTTTATAAAAGAAGATTTGAATACAGCGAAAGATAGTTGGAAAGATGTAAA
AGATTATACAGAAAAATTACATGAAGGCGTGGCGAAGTAA

Upstream 100 bases:

>100_bases
CGAATCGTTAGAGCGTTGCGTATTGATAAAAGATTTGAAGCTCCTGTTCAGTTGTGAGCAGGAGCTTTTTATACCCTTAT
AAAGAAAATAGGTGAAAAGT

Downstream 100 bases:

>100_bases
ACAGTGGACTAGTTCTGCTGTTTATTTTTTATCTTGTTTTTTGAAAGCTGAACTTATCATTTGATATATAAGTTTGCCAT
GTGTTTTATCAATGTAGCTT

Product: enterotoxin C

Products: NA

Alternate protein names: Enterotoxin 40 kDa subunit [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MQKRFYKKCLLTLMIAGVATSNAFPLHPFAAEQNVKTLQESAKNYSLGPAGFQDVMAQTTSSIFAMDSYAKLIQNQQETD
LSKISSINSEFKGNMMQHQRDAKINAAYWLDRMKPQIMKTDQNIINYNNTFQAYYNSMLIAIDQKDSVKLKADLEKLYAD
IVKNQNEVDVLLGDLKTFRDRMAKDTNSFKEDTNRLTSILASTNAGIPALEQQINTYNDSIKKSNDMVIAGGVLCVALIT
CLAGGPMIAVAKKDIANAEREIANLKDRISGAQAEVAILTDVKNKTTNMTETIDAAITALQNISNQWYTVGAKYNNLLQN
VKGISPEEFTFIKEDLNTAKDSWKDVKDYTEKLHEGVAK

Sequences:

>Translated_359_residues
MQKRFYKKCLLTLMIAGVATSNAFPLHPFAAEQNVKTLQESAKNYSLGPAGFQDVMAQTTSSIFAMDSYAKLIQNQQETD
LSKISSINSEFKGNMMQHQRDAKINAAYWLDRMKPQIMKTDQNIINYNNTFQAYYNSMLIAIDQKDSVKLKADLEKLYAD
IVKNQNEVDVLLGDLKTFRDRMAKDTNSFKEDTNRLTSILASTNAGIPALEQQINTYNDSIKKSNDMVIAGGVLCVALIT
CLAGGPMIAVAKKDIANAEREIANLKDRISGAQAEVAILTDVKNKTTNMTETIDAAITALQNISNQWYTVGAKYNNLLQN
VKGISPEEFTFIKEDLNTAKDSWKDVKDYTEKLHEGVAK
>Mature_359_residues
MQKRFYKKCLLTLMIAGVATSNAFPLHPFAAEQNVKTLQESAKNYSLGPAGFQDVMAQTTSSIFAMDSYAKLIQNQQETD
LSKISSINSEFKGNMMQHQRDAKINAAYWLDRMKPQIMKTDQNIINYNNTFQAYYNSMLIAIDQKDSVKLKADLEKLYAD
IVKNQNEVDVLLGDLKTFRDRMAKDTNSFKEDTNRLTSILASTNAGIPALEQQINTYNDSIKKSNDMVIAGGVLCVALIT
CLAGGPMIAVAKKDIANAEREIANLKDRISGAQAEVAILTDVKNKTTNMTETIDAAITALQNISNQWYTVGAKYNNLLQN
VKGISPEEFTFIKEDLNTAKDSWKDVKDYTEKLHEGVAK

Specific function: Cytotoxic protein, part of the enterotoxin complex. Responsible for binding to erythrocytes. This enterotoxin is thought to be the cause of the diarrheal form of gastroenteritis caused by food-borne strains of B.cereus [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cell membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008414
- InterPro:   IPR010356 [H]

Pfam domain/function: PF05791 Bacillus_HBL [H]

EC number: NA

Molecular weight: Translated: 40045; Mature: 40045

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKRFYKKCLLTLMIAGVATSNAFPLHPFAAEQNVKTLQESAKNYSLGPAGFQDVMAQTT
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
SSIFAMDSYAKLIQNQQETDLSKISSINSEFKGNMMQHQRDAKINAAYWLDRMKPQIMKT
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHCHHHHHC
DQNIINYNNTFQAYYNSMLIAIDQKDSVKLKADLEKLYADIVKNQNEVDVLLGDLKTFRD
CCHHHCCCCHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RMAKDTNSFKEDTNRLTSILASTNAGIPALEQQINTYNDSIKKSNDMVIAGGVLCVALIT
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHH
CLAGGPMIAVAKKDIANAEREIANLKDRISGAQAEVAILTDVKNKTTNMTETIDAAITAL
HHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
QNISNQWYTVGAKYNNLLQNVKGISPEEFTFIKEDLNTAKDSWKDVKDYTEKLHEGVAK
HHCCCCEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQKRFYKKCLLTLMIAGVATSNAFPLHPFAAEQNVKTLQESAKNYSLGPAGFQDVMAQTT
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
SSIFAMDSYAKLIQNQQETDLSKISSINSEFKGNMMQHQRDAKINAAYWLDRMKPQIMKT
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHCHHHHHC
DQNIINYNNTFQAYYNSMLIAIDQKDSVKLKADLEKLYADIVKNQNEVDVLLGDLKTFRD
CCHHHCCCCHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RMAKDTNSFKEDTNRLTSILASTNAGIPALEQQINTYNDSIKKSNDMVIAGGVLCVALIT
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHH
CLAGGPMIAVAKKDIANAEREIANLKDRISGAQAEVAILTDVKNKTTNMTETIDAAITAL
HHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
QNISNQWYTVGAKYNNLLQNVKGISPEEFTFIKEDLNTAKDSWKDVKDYTEKLHEGVAK
HHCCCCEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7693651; 8319899 [H]