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The map label for this gene is katE [H]

Identifier: 218902057

GI number: 218902057

Start: 891439

End: 893436

Strand: Reverse

Name: katE [H]

Synonym: BCAH820_0939

Alternate gene names: 218902057

Gene position: 893436-891439 (Counterclockwise)

Preceding gene: 218902058

Following gene: 218902056

Centisome position: 16.85

GC content: 38.24

Gene sequence:

>1998_bases
GTGAATAAAAAAATGGAGCAATTGGAACACCACGTTACGGATAATCAACGCAAACATGCTTTAACAACAAACCAAGGGGT
AAAAATAGCTGAAGATGAATTTTCTTTAAAGATGGGCTTAAGAGGCCCAACCTTAATGGAGGATTTCCACTTTCGCGAGA
AAATGACCCATTTTGATCACGAACGAATTCCCGAAAGAATTGTTCATGCACGCGGAGTTGGCGCTCATGGTTATTTTCAG
CTTTATGAATCGTTAGAAGCATATACGAAAGCAGATTTTCTTACTAATCCTTCAAAGAAAACACCTGTATTTGTACGTTT
TTCAACCGTTCAAGGTTCTAAAGGATCCAACGACACAGTAAGAGATGTACGCGGATTCGCCACAAAATTTTATACAGATG
AAGGGAACTACGATTTAGTAGGTAATAATATGCCAGTATTCTTTATCCAAGATGCTATTAAATTTCCTGATTTTGTCCAT
GCGGTTAAACCAGAACCACATAACGACATTCCTCAGGGGGCTAGCGCTCATGATACCTTTTGGGATTTTGTTGCACATAA
TCCTGAGTCCACGCATATGGTCATGTGGCAAATGAGCGACCGTGCTATTCCGCGTAGTTTACGAATGATGGAAGGTTTTG
GAGTTCACACATTTCGACTCATTAACGCAGAAGGAAAAGCCCATTTCGTAAAGTTTCACTGGAAACCCGCTCTTGGAGTT
CATTCATTAGTGTGGGATGAGGCTCAAAAAATTGCTGGGAAAAATCCTGATTTCCATCGTCAAGATTTATATGAAGCAAT
TGAAAAAGGGGATTATCCGGAATGGGAGCTCGGATTACAGCTAATTCCAGAAGAAGATGAGCATGCATTTGATTTTGATA
TTTTAGATCCAACGAAATTATGGCCGGAAGAAGAAGTTCCTGTAAAACTAGTTGGTAAAATGACATTGAACAAAAATGTT
GATAACTTCTTTGCGGAAACGGAGCAGGTAGCATTCCACCCTGGTCATGTCGTACCAGGTATTGATTTTTCAAATGACCC
TCTTCTGCAAGGAAGATTATTCTCCTATACAGATACACAATTATCTCGTTTAGGAGGTCCTAATTTCCATCAAATCCCTA
TTAATCAGCCCGTATGTCCTTTTCATAATAATCAACGTGATGGTATGCATCAAATGCAAATCCATCGCGGTCAAACAAGC
TATCATCCTAATGGCTTAAATGACAATCAACCAGCAACCGTGCAAGCTGAACAGGGCGGATATGAGCATTATCAAGAAAA
GATTGATGGACATAAAATTAGGGGGCGCAGTAAAAGCTTCCTTAACTTTTATTCGCAAGCTAAACTTTTCTACAATAGTA
TGAGCCCTATTGAAAAGCAGCATATAAAAGAAGCTTTTTGCTTTGAAGTTGGGAAGTGTAAATCAGACATGGTGAAGGCA
AATGTAATTGCTCTACTGAATCATGTCGATCGTCAATTAGCACAAGAAGTCGCTAACATTATTGGAGCTCCCTTGCCTAA
GGAAAATCGCGAAGTAAATTCAGATGCAAAATCACCTGCACTAAGTATGTCCAATACTATTTTTAAAGCTGATTCTAAAA
ATGTTGCAATTGTATTAAATGGTGACCCAAGCGTCTCCCTTCTGTCCGAATGGATTCAAGCTTTTGCACAGCATCGAATT
AACTATAGCATCGTAGATAATAAAATTTATCAGTTCAATGATTCCATTAAAGTAACTGATACTTATACAACAACAGACTC
TTCCCTTTTTGACGCAGTATTAGTGTTTAGTAGTGAGTCTGTCATTCACCCCCCTGTTTTAGAATTTGCAGAAACTACTT
TTAAACATTTTAAACCGATAGCCTATGTCCTTAGTAATCCTCATTCTTTGGACAATAGTAAAATTAAATTAGATGGGGCA
GGAATTTACAACTTAGCAAACACTTCAATTGAATCATTTATAGAAGGTATTGCCCAAGGACGATTTTGGAATCGATAA

Upstream 100 bases:

>100_bases
CGATATTTTTTGATTTTTACATACAAAAACGATAATACATGTTTACGTCCTAATAAAAAGGGTATCTATTAATTAACAGA
GTAAAGGAGGGGCCTATATT

Downstream 100 bases:

>100_bases
TATAATGTAAGGAGCGGATTAGAATGAGTAAAAAAATTGCTATTTTAATAACGGATTATTTCGAGGACACAGAATACACA
GAGCCAGCAGAAGCTTTTAA

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 665; Mature: 665

Protein sequence:

>665_residues
MNKKMEQLEHHVTDNQRKHALTTNQGVKIAEDEFSLKMGLRGPTLMEDFHFREKMTHFDHERIPERIVHARGVGAHGYFQ
LYESLEAYTKADFLTNPSKKTPVFVRFSTVQGSKGSNDTVRDVRGFATKFYTDEGNYDLVGNNMPVFFIQDAIKFPDFVH
AVKPEPHNDIPQGASAHDTFWDFVAHNPESTHMVMWQMSDRAIPRSLRMMEGFGVHTFRLINAEGKAHFVKFHWKPALGV
HSLVWDEAQKIAGKNPDFHRQDLYEAIEKGDYPEWELGLQLIPEEDEHAFDFDILDPTKLWPEEEVPVKLVGKMTLNKNV
DNFFAETEQVAFHPGHVVPGIDFSNDPLLQGRLFSYTDTQLSRLGGPNFHQIPINQPVCPFHNNQRDGMHQMQIHRGQTS
YHPNGLNDNQPATVQAEQGGYEHYQEKIDGHKIRGRSKSFLNFYSQAKLFYNSMSPIEKQHIKEAFCFEVGKCKSDMVKA
NVIALLNHVDRQLAQEVANIIGAPLPKENREVNSDAKSPALSMSNTIFKADSKNVAIVLNGDPSVSLLSEWIQAFAQHRI
NYSIVDNKIYQFNDSIKVTDTYTTTDSSLFDAVLVFSSESVIHPPVLEFAETTFKHFKPIAYVLSNPHSLDNSKIKLDGA
GIYNLANTSIESFIEGIAQGRFWNR

Sequences:

>Translated_665_residues
MNKKMEQLEHHVTDNQRKHALTTNQGVKIAEDEFSLKMGLRGPTLMEDFHFREKMTHFDHERIPERIVHARGVGAHGYFQ
LYESLEAYTKADFLTNPSKKTPVFVRFSTVQGSKGSNDTVRDVRGFATKFYTDEGNYDLVGNNMPVFFIQDAIKFPDFVH
AVKPEPHNDIPQGASAHDTFWDFVAHNPESTHMVMWQMSDRAIPRSLRMMEGFGVHTFRLINAEGKAHFVKFHWKPALGV
HSLVWDEAQKIAGKNPDFHRQDLYEAIEKGDYPEWELGLQLIPEEDEHAFDFDILDPTKLWPEEEVPVKLVGKMTLNKNV
DNFFAETEQVAFHPGHVVPGIDFSNDPLLQGRLFSYTDTQLSRLGGPNFHQIPINQPVCPFHNNQRDGMHQMQIHRGQTS
YHPNGLNDNQPATVQAEQGGYEHYQEKIDGHKIRGRSKSFLNFYSQAKLFYNSMSPIEKQHIKEAFCFEVGKCKSDMVKA
NVIALLNHVDRQLAQEVANIIGAPLPKENREVNSDAKSPALSMSNTIFKADSKNVAIVLNGDPSVSLLSEWIQAFAQHRI
NYSIVDNKIYQFNDSIKVTDTYTTTDSSLFDAVLVFSSESVIHPPVLEFAETTFKHFKPIAYVLSNPHSLDNSKIKLDGA
GIYNLANTSIESFIEGIAQGRFWNR
>Mature_665_residues
MNKKMEQLEHHVTDNQRKHALTTNQGVKIAEDEFSLKMGLRGPTLMEDFHFREKMTHFDHERIPERIVHARGVGAHGYFQ
LYESLEAYTKADFLTNPSKKTPVFVRFSTVQGSKGSNDTVRDVRGFATKFYTDEGNYDLVGNNMPVFFIQDAIKFPDFVH
AVKPEPHNDIPQGASAHDTFWDFVAHNPESTHMVMWQMSDRAIPRSLRMMEGFGVHTFRLINAEGKAHFVKFHWKPALGV
HSLVWDEAQKIAGKNPDFHRQDLYEAIEKGDYPEWELGLQLIPEEDEHAFDFDILDPTKLWPEEEVPVKLVGKMTLNKNV
DNFFAETEQVAFHPGHVVPGIDFSNDPLLQGRLFSYTDTQLSRLGGPNFHQIPINQPVCPFHNNQRDGMHQMQIHRGQTS
YHPNGLNDNQPATVQAEQGGYEHYQEKIDGHKIRGRSKSFLNFYSQAKLFYNSMSPIEKQHIKEAFCFEVGKCKSDMVKA
NVIALLNHVDRQLAQEVANIIGAPLPKENREVNSDAKSPALSMSNTIFKADSKNVAIVLNGDPSVSLLSEWIQAFAQHRI
NYSIVDNKIYQFNDSIKVTDTYTTTDSSLFDAVLVFSSESVIHPPVLEFAETTFKHFKPIAYVLSNPHSLDNSKIKLDGA
GIYNLANTSIESFIEGIAQGRFWNR

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. Involved in sporulation [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family. HPII subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=407, Percent_Identity=45.4545454545455, Blast_Score=363, Evalue=1e-100,
Organism=Escherichia coli, GI48994891, Length=691, Percent_Identity=54.4138929088278, Blast_Score=730, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25151141, Length=407, Percent_Identity=48.4029484029484, Blast_Score=395, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI71998444, Length=487, Percent_Identity=41.8891170431211, Blast_Score=391, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI25147792, Length=406, Percent_Identity=47.5369458128079, Blast_Score=388, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6320462, Length=522, Percent_Identity=37.7394636015326, Blast_Score=334, Evalue=2e-92,
Organism=Saccharomyces cerevisiae, GI6321525, Length=367, Percent_Identity=42.2343324250681, Blast_Score=300, Evalue=4e-82,
Organism=Drosophila melanogaster, GI17981717, Length=396, Percent_Identity=45.7070707070707, Blast_Score=357, Evalue=2e-98,
Organism=Drosophila melanogaster, GI19920968, Length=404, Percent_Identity=40.8415841584158, Blast_Score=340, Evalue=2e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614
- InterPro:   IPR002818 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel; PF01965 DJ-1_PfpI [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 75733; Mature: 75733

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00437 CATALASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKMEQLEHHVTDNQRKHALTTNQGVKIAEDEFSLKMGLRGPTLMEDFHFREKMTHFDH
CCHHHHHHHHHHCCCCCCEEEECCCCCEEECCCEEEEECCCCCHHHHHHHHHHHHHHCCH
ERIPERIVHARGVGAHGYFQLYESLEAYTKADFLTNPSKKTPVFVRFSTVQGSKGSNDTV
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCHH
RDVRGFATKFYTDEGNYDLVGNNMPVFFIQDAIKFPDFVHAVKPEPHNDIPQGASAHDTF
HHHHHHHHHEEECCCCEEEECCCCCEEEECCHHCCCHHHHHCCCCCCCCCCCCCCCCHHH
WDFVAHNPESTHMVMWQMSDRAIPRSLRMMEGFGVHTFRLINAEGKAHFVKFHWKPALGV
HHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCCH
HSLVWDEAQKIAGKNPDFHRQDLYEAIEKGDYPEWELGLQLIPEEDEHAFDFDILDPTKL
HHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCEEEEECCCCHHC
WPEEEVPVKLVGKMTLNKNVDNFFAETEQVAFHPGHVVPGIDFSNDPLLQGRLFSYTDTQ
CCCCCCCEEEEEEEEECCCHHHHHHCCHHEEECCCCCCCCCCCCCCCCCCCEEEECCHHH
LSRLGGPNFHQIPINQPVCPFHNNQRDGMHQMQIHRGQTSYHPNGLNDNQPATVQAEQGG
HHHCCCCCEEECCCCCCCCCCCCCCCCCHHHHHEECCCCCCCCCCCCCCCCCEEEECCCC
YEHYQEKIDGHKIRGRSKSFLNFYSQAKLFYNSMSPIEKQHIKEAFCFEVGKCKSDMVKA
HHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHH
NVIALLNHVDRQLAQEVANIIGAPLPKENREVNSDAKSPALSMSNTIFKADSKNVAIVLN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEC
GDPSVSLLSEWIQAFAQHRINYSIVDNKIYQFNDSIKVTDTYTTTDSSLFDAVLVFSSES
CCCCHHHHHHHHHHHHHHCCCEEEECCEEEEECCCEEEEEEEECCCHHHHHHHHEECCCC
VIHPPVLEFAETTFKHFKPIAYVLSNPHSLDNSKIKLDGAGIYNLANTSIESFIEGIAQG
CCCCHHHHHHHHHHHHHCCHHHHHCCCCCCCCCEEEECCCCEEHHHHHHHHHHHHHHHCC
RFWNR
CCCCC
>Mature Secondary Structure
MNKKMEQLEHHVTDNQRKHALTTNQGVKIAEDEFSLKMGLRGPTLMEDFHFREKMTHFDH
CCHHHHHHHHHHCCCCCCEEEECCCCCEEECCCEEEEECCCCCHHHHHHHHHHHHHHCCH
ERIPERIVHARGVGAHGYFQLYESLEAYTKADFLTNPSKKTPVFVRFSTVQGSKGSNDTV
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCHH
RDVRGFATKFYTDEGNYDLVGNNMPVFFIQDAIKFPDFVHAVKPEPHNDIPQGASAHDTF
HHHHHHHHHEEECCCCEEEECCCCCEEEECCHHCCCHHHHHCCCCCCCCCCCCCCCCHHH
WDFVAHNPESTHMVMWQMSDRAIPRSLRMMEGFGVHTFRLINAEGKAHFVKFHWKPALGV
HHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCCCCH
HSLVWDEAQKIAGKNPDFHRQDLYEAIEKGDYPEWELGLQLIPEEDEHAFDFDILDPTKL
HHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCEEEEECCCCHHC
WPEEEVPVKLVGKMTLNKNVDNFFAETEQVAFHPGHVVPGIDFSNDPLLQGRLFSYTDTQ
CCCCCCCEEEEEEEEECCCHHHHHHCCHHEEECCCCCCCCCCCCCCCCCCCEEEECCHHH
LSRLGGPNFHQIPINQPVCPFHNNQRDGMHQMQIHRGQTSYHPNGLNDNQPATVQAEQGG
HHHCCCCCEEECCCCCCCCCCCCCCCCCHHHHHEECCCCCCCCCCCCCCCCCEEEECCCC
YEHYQEKIDGHKIRGRSKSFLNFYSQAKLFYNSMSPIEKQHIKEAFCFEVGKCKSDMVKA
HHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHH
NVIALLNHVDRQLAQEVANIIGAPLPKENREVNSDAKSPALSMSNTIFKADSKNVAIVLN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEC
GDPSVSLLSEWIQAFAQHRINYSIVDNKIYQFNDSIKVTDTYTTTDSSLFDAVLVFSSES
CCCCHHHHHHHHHHHHHHCCCEEEECCEEEEECCCEEEEEEEECCCHHHHHHHHEECCCC
VIHPPVLEFAETTFKHFKPIAYVLSNPHSLDNSKIKLDGAGIYNLANTSIESFIEGIAQG
CCCCHHHHHHHHHHHHHCCHHHHHCCCCCCCCCEEEECCCCEEHHHHHHHHHHHHHHHCC
RFWNR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]