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The map label for this gene is argF1 [H]

Identifier: 218901566

GI number: 218901566

Start: 394553

End: 395551

Strand: Direct

Name: argF1 [H]

Synonym: BCAH820_0408

Alternate gene names: 218901566

Gene position: 394553-395551 (Clockwise)

Preceding gene: 218901565

Following gene: 218901567

Centisome position: 7.44

GC content: 34.43

Gene sequence:

>999_bases
ATGTTAATGACTAGACCAAACTTAAAAGGAAGAAGCTTTCTAGCAGAAAAAGATTTTACACAAGAAGAATTGTTATATTT
TCTAGATTTGGCAGCAGAATTAAAAGAGAAAAAGAAAAATGGTATCCCGCATCATTATTTAGAAGGTAAAAATGTAGCGC
TCTTATTTGAAAAAACTTCTACTCGTACGCGTTGTGCATTTACAGTAGCATGTACAGATTTAGGAGCGAATCCTGAATAT
TTAGGGAAAGGTGATATTCAGCTTGGGAAAAAAGAATCTGTAGAGGATACAGCAAAAGTGTTAGGGCGTATGTTTGACGG
AATTGAGTTTCGTGGATTTAATCATGAAACTGTAGAATCTTTAGCACAAAATTCTGGTGTGCCAGTTTGGAATGGATTAA
CAGATATGTGGCATCCAACACAAACATTAGCAGATTTATTAACTATTAGGGAACATGTAGGGAAATTAAAAAATGTGAAG
CTTGTTTACGTTGGAGATGGACGAAATAATGTTGCTAATAGTTTACTAGTTGGTGGAGCAATCGTTGGAATGGATGTACG
TATTTGTACACCGGAATCTTTATGGCCTGCACAAGAAGTAATTGATTTAGCAAAAAAATATAATGAACAAGTAATGATAA
CAAGTAATGTGGAAGAAGCTGTTGCGAGTGCAGATGTAATTTATACAGATGTATGGGTGTCTATGGGGGAAGAAGAAAAA
TTTGCTGAACGTGTCGAGTTATTGAAACCTTATCAAGTAAATATGAAAATGATTAAAGAAACAGGGAATAAAAACGTGAT
TTTCTTACATTGTTTACCTGCATTTCATGATGTTGAAACGATGTATGGCGAAGAAGTTTATGAGAAATATGGGTTAAAAG
AAATGGAGGTAACTGACGAAGTATTCCGCAGTAAACATTCAAAAGTATTTGATCAAGCTGAAAATAGAATGCATACAATT
AAAGCGGTTATGGCAGCTACTTTAGGGAACATGGAGTAA

Upstream 100 bases:

>100_bases
TTCGGAATTATCTCGTGGTCGTGGGGGTCCACGTTGTATGAGTATGCCAATTGTTCGTAAAGATATTTAGTATAAATAAC
GGAGAAAGTAGGGATGAAGT

Downstream 100 bases:

>100_bases
AGAAGAAAGGGAGTTTTCCTTTCTTCTTTCTCCTCCTTTAGACACTATCATTCACTATTGCTTTTGTATTGTTATTGCAA
TTTAAGAGAGGTGAGTGGAA

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MLMTRPNLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEGKNVALLFEKTSTRTRCAFTVACTDLGANPEY
LGKGDIQLGKKESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIREHVGKLKNVK
LVYVGDGRNNVANSLLVGGAIVGMDVRICTPESLWPAQEVIDLAKKYNEQVMITSNVEEAVASADVIYTDVWVSMGEEEK
FAERVELLKPYQVNMKMIKETGNKNVIFLHCLPAFHDVETMYGEEVYEKYGLKEMEVTDEVFRSKHSKVFDQAENRMHTI
KAVMAATLGNME

Sequences:

>Translated_332_residues
MLMTRPNLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEGKNVALLFEKTSTRTRCAFTVACTDLGANPEY
LGKGDIQLGKKESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIREHVGKLKNVK
LVYVGDGRNNVANSLLVGGAIVGMDVRICTPESLWPAQEVIDLAKKYNEQVMITSNVEEAVASADVIYTDVWVSMGEEEK
FAERVELLKPYQVNMKMIKETGNKNVIFLHCLPAFHDVETMYGEEVYEKYGLKEMEVTDEVFRSKHSKVFDQAENRMHTI
KAVMAATLGNME
>Mature_332_residues
MLMTRPNLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEGKNVALLFEKTSTRTRCAFTVACTDLGANPEY
LGKGDIQLGKKESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIREHVGKLKNVK
LVYVGDGRNNVANSLLVGGAIVGMDVRICTPESLWPAQEVIDLAKKYNEQVMITSNVEEAVASADVIYTDVWVSMGEEEK
FAERVELLKPYQVNMKMIKETGNKNVIFLHCLPAFHDVETMYGEEVYEKYGLKEMEVTDEVFRSKHSKVFDQAENRMHTI
KAVMAATLGNME

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=332, Percent_Identity=39.1566265060241, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI18105007, Length=336, Percent_Identity=25, Blast_Score=86, Evalue=7e-17,
Organism=Escherichia coli, GI1786469, Length=331, Percent_Identity=55.2870090634441, Blast_Score=357, Evalue=1e-100,
Organism=Escherichia coli, GI1790703, Length=326, Percent_Identity=56.1349693251534, Blast_Score=356, Evalue=1e-99,
Organism=Escherichia coli, GI48994908, Length=370, Percent_Identity=26.7567567567568, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI2367364, Length=342, Percent_Identity=27.7777777777778, Blast_Score=84, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI193204318, Length=264, Percent_Identity=28.030303030303, Blast_Score=82, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6322373, Length=337, Percent_Identity=34.4213649851632, Blast_Score=175, Evalue=9e-45,
Organism=Saccharomyces cerevisiae, GI6322331, Length=281, Percent_Identity=24.1992882562278, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24642586, Length=329, Percent_Identity=25.8358662613982, Blast_Score=88, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 37478; Mature: 37478

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMTRPNLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEGKNVALLFEKTS
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCC
TRTRCAFTVACTDLGANPEYLGKGDIQLGKKESVEDTAKVLGRMFDGIEFRGFNHETVES
CCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEECCCCHHHHHH
LAQNSGVPVWNGLTDMWHPTQTLADLLTIREHVGKLKNVKLVYVGDGRNNVANSLLVGGA
HHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHCHHHCEEEEEEECCCCHHHHHHHHCCE
IVGMDVRICTPESLWPAQEVIDLAKKYNEQVMITSNVEEAVASADVIYTDVWVSMGEEEK
EEECEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHEEHHHHHCCCHHH
FAERVELLKPYQVNMKMIKETGNKNVIFLHCLPAFHDVETMYGEEVYEKYGLKEMEVTDE
HHHHHHHHCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHH
VFRSKHSKVFDQAENRMHTIKAVMAATLGNME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLMTRPNLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEGKNVALLFEKTS
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCC
TRTRCAFTVACTDLGANPEYLGKGDIQLGKKESVEDTAKVLGRMFDGIEFRGFNHETVES
CCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEECCCCHHHHHH
LAQNSGVPVWNGLTDMWHPTQTLADLLTIREHVGKLKNVKLVYVGDGRNNVANSLLVGGA
HHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHCHHHCEEEEEEECCCCHHHHHHHHCCE
IVGMDVRICTPESLWPAQEVIDLAKKYNEQVMITSNVEEAVASADVIYTDVWVSMGEEEK
EEECEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHEEHHHHHCCCHHH
FAERVELLKPYQVNMKMIKETGNKNVIFLHCLPAFHDVETMYGEEVYEKYGLKEMEVTDE
HHHHHHHHCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHH
VFRSKHSKVFDQAENRMHTIKAVMAATLGNME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA