Click here to switch to the map view.

The map label for this gene is arcD [H]

Identifier: 218901567

GI number: 218901567

Start: 395651

End: 397066

Strand: Direct

Name: arcD [H]

Synonym: BCAH820_0409

Alternate gene names: 218901567

Gene position: 395651-397066 (Clockwise)

Preceding gene: 218901566

Following gene: 218901568

Centisome position: 7.46

GC content: 35.45

Gene sequence:

>1416_bases
ATGGGTGAAGATAAGAAATTAGGGTTGTTTACATTAACGGCTCTTGTAGTTGGGTCTATGATTGGCGGTGGAGCCTTTAA
TTTAGCGAGTGATATGGCAAAAGGTGCTGGTGCTGGAGCCATTATTATTGGCTGGGTTATAACAGGAATTGGGATGATTG
CACTTGGATTATCTTTTCAAAATCTAACTGTAAAACGGCCAGATTTAGATGGTGGTATTTTTAGCTATGCAAAAGCAGGG
TTTGGTAATTTTATGGGATTTAATAGTGCATGGGGATACTGGCTATCTGCTTGGCTTGGGAATGTAGCTTACGGTACATT
ATTGTTTTCTTCATTAGGATATTTCTTCCCAATCTTTGAAGGCGGGCAAAATGTAGCGTCCATTATTGGTGCAAGCGTTT
TATTATGGTGTGTTCACATGTTAATTTTACGTGGAGTTCAATCAGCAGCACTTGTGAATTTAGTAACTACAATCGCAAAA
TTAGTACCTGTATTTGTATTTATTGTCATAGGAATCTTCGCGTTTCATATTGACACGTTCTTAGATGGATTTTGGGGGCA
AACTGGTTCTTTTTCATGGGAAGCAGTTGGCAGCCAAGTTAAAAGTACGATGCTTGTAACTTTATGGGTATTTATTGGGG
TAGAAGGAGCTGTTGTTTTATCAAGTCGAGCAAAAAATAGAAGTGATGTAGGGAAAGCAACGGTTATTGGCTTAATTGGT
ACACTCATCATTTACATTTTAATCACATTATTGTCTCTTGGACTTATGCAACAAGCAGATATTGCAGGTCTGAAAAATCC
GGCTATGGCTTATTTATTTGAAAGTGTTGTTGGAAAATGGGGTGCTATCTTTATTAATTTAGGTTTAGTCATCTCTGTAT
TAGGTGCTTGGTTAGGTTGGACTTTGCTCGCTTCTGAAATTCCATATTTAGCGGCTAAAGATGGAGTATTTCCAAAATGG
TTCGCAAAAGAAAATAAAAATAAAGCTCCAGTAAATTCATTATGGATAACAAATGGTTTAATTCAAATGTTCTTGTTAAC
ATTTGTCGTTTCTGATCAGGCTTATAACTTTGCATTTTCTTTAGCATCTTCAGCTATTTTAATCCCATATGCTTTTTCAG
CATTTTATCAACTGAAGCATAGCTTAAAGTCTGAAGGAGCAGATCGAAATAAAAATATAATAATTGGCTTAATAGCAAGT
ATTTATGGCGTGTGGTTAGTTTATGCAGCTGGTTTAGAGTATTTATTATTAACAATGACTTTATATGCGCCAGGTATTTT
TATTTTTTACAATGTTCAAAAGCAAAAGAGTTCGAAGAAAATATTTACTCGAGTGGAATTAGCATCATCCGTAGCAATTG
GTGCTTTAGCATTCTTTGCGATTTATGGATTAATTACAGGCAGTATTACTTTATAA

Upstream 100 bases:

>100_bases
AAGAAGAAAGGGAGTTTTCCTTTCTTCTTTCTCCTCCTTTAGACACTATCATTCACTATTGCTTTTGTATTGTTATTGCA
ATTTAAGAGAGGTGAGTGGA

Downstream 100 bases:

>100_bases
AGCGCTGTGAAAGCGAAATCAACAGGAGGGCTGGAATATGGCACGAAGAAAAATTGTAGTTGCACTAGGGGGAAATGCGA
TACAGTCTGGAGAAGCTACT

Product: arginine/ornithine antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MGEDKKLGLFTLTALVVGSMIGGGAFNLASDMAKGAGAGAIIIGWVITGIGMIALGLSFQNLTVKRPDLDGGIFSYAKAG
FGNFMGFNSAWGYWLSAWLGNVAYGTLLFSSLGYFFPIFEGGQNVASIIGASVLLWCVHMLILRGVQSAALVNLVTTIAK
LVPVFVFIVIGIFAFHIDTFLDGFWGQTGSFSWEAVGSQVKSTMLVTLWVFIGVEGAVVLSSRAKNRSDVGKATVIGLIG
TLIIYILITLLSLGLMQQADIAGLKNPAMAYLFESVVGKWGAIFINLGLVISVLGAWLGWTLLASEIPYLAAKDGVFPKW
FAKENKNKAPVNSLWITNGLIQMFLLTFVVSDQAYNFAFSLASSAILIPYAFSAFYQLKHSLKSEGADRNKNIIIGLIAS
IYGVWLVYAAGLEYLLLTMTLYAPGIFIFYNVQKQKSSKKIFTRVELASSVAIGALAFFAIYGLITGSITL

Sequences:

>Translated_471_residues
MGEDKKLGLFTLTALVVGSMIGGGAFNLASDMAKGAGAGAIIIGWVITGIGMIALGLSFQNLTVKRPDLDGGIFSYAKAG
FGNFMGFNSAWGYWLSAWLGNVAYGTLLFSSLGYFFPIFEGGQNVASIIGASVLLWCVHMLILRGVQSAALVNLVTTIAK
LVPVFVFIVIGIFAFHIDTFLDGFWGQTGSFSWEAVGSQVKSTMLVTLWVFIGVEGAVVLSSRAKNRSDVGKATVIGLIG
TLIIYILITLLSLGLMQQADIAGLKNPAMAYLFESVVGKWGAIFINLGLVISVLGAWLGWTLLASEIPYLAAKDGVFPKW
FAKENKNKAPVNSLWITNGLIQMFLLTFVVSDQAYNFAFSLASSAILIPYAFSAFYQLKHSLKSEGADRNKNIIIGLIAS
IYGVWLVYAAGLEYLLLTMTLYAPGIFIFYNVQKQKSSKKIFTRVELASSVAIGALAFFAIYGLITGSITL
>Mature_470_residues
GEDKKLGLFTLTALVVGSMIGGGAFNLASDMAKGAGAGAIIIGWVITGIGMIALGLSFQNLTVKRPDLDGGIFSYAKAGF
GNFMGFNSAWGYWLSAWLGNVAYGTLLFSSLGYFFPIFEGGQNVASIIGASVLLWCVHMLILRGVQSAALVNLVTTIAKL
VPVFVFIVIGIFAFHIDTFLDGFWGQTGSFSWEAVGSQVKSTMLVTLWVFIGVEGAVVLSSRAKNRSDVGKATVIGLIGT
LIIYILITLLSLGLMQQADIAGLKNPAMAYLFESVVGKWGAIFINLGLVISVLGAWLGWTLLASEIPYLAAKDGVFPKWF
AKENKNKAPVNSLWITNGLIQMFLLTFVVSDQAYNFAFSLASSAILIPYAFSAFYQLKHSLKSEGADRNKNIIIGLIASI
YGVWLVYAAGLEYLLLTMTLYAPGIFIFYNVQKQKSSKKIFTRVELASSVAIGALAFFAIYGLITGSITL

Specific function: Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787890, Length=450, Percent_Identity=47.1111111111111, Blast_Score=404, Evalue=1e-114,
Organism=Escherichia coli, GI2367353, Length=417, Percent_Identity=30.2158273381295, Blast_Score=165, Evalue=5e-42,
Organism=Escherichia coli, GI1786908, Length=425, Percent_Identity=26.3529411764706, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1790575, Length=419, Percent_Identity=27.2076372315036, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI87082250, Length=360, Percent_Identity=26.1111111111111, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004754
- InterPro:   IPR022461 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50592; Mature: 50461

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCEEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GEDKKLGLFTLTALVVGSMIGGGAFNLASDMAKGAGAGAIIIGWVITGIGMIALGLSFQ
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC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HHCCCEEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9053381; 11792842 [H]