BacMap

Definition	Desulfurococcus kamchatkensis 1221n chromosome, complete genome.
Accession	NC_011766
Length	1,365,223

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The map label for this gene is fabG [H]

Identifier: 218884712

GI number: 218884712

Start: 1304159

End: 1304947

Strand: Reverse

Name: fabG [H]

Synonym: DKAM_1401

Alternate gene names: 218884712

Gene position: 1304947-1304159 (Counterclockwise)

Preceding gene: 218884713

Following gene: 218884709

Centisome position: 95.58

GC content: 45.5

Gene sequence:

>789_bases
ATGGGTATAGTTGAAGGACTGCGTGTTCTTGTAACGGCTTCCACGAGAGGCCTTGGAAGGGGTGCTGCTGAAGCATTACT
AGAGGAGGGTGCGAAAGTCGTTATAAATGGGAGAAGCCGGGATAATGTTGAGAAAACCCTTGGAGAACTGAAAAGTAGAT
TTGGTGATAGAGTTCACGGGGTTGCTGCTGATTTAACCGTTAGGGGGGATGTCTATAGGCTGGTGGATGAGGCTGTGAAG
TTCCTCGGGGGCCTTGACTCAATAATCTACATAACCGGTCCTCCTAGACCTGGCACATTTCAGGAGATACGCGAAGATGA
ATGGGAGTATAATGCAAGACTCCTTGTCTTCAATGCGATATGGATTGTCAATGCTTCTCTCCCATACTTAAGGAAGTCAA
GTAATCCCTCGATAATCTTTTCAACTAGTTTAGCAGTTAAGGAACCAATAGATATCCTGGCATTATCAAACGTCCTCAGG
CTAAGTATCCATGGCTTGGTTAAAACACTCGCTAAAGAGCTCGGCCGTGAGGGAATAAGGGTTAATGCAGTGATGCCAGG
CTACATCGAGACTGATAGAATAAGAAAACTGATCGAGGATAGAGCCAGGAGGGGGAACAAGTCATACGAGGAGGCATATA
GGGAATTCGTCAGCGATATACCTTTAGGAAGGCTTGGCTCACCAATAGAGTACGGTAGAGTAATAGTGTTCCTAGCAAGC
AGGTATGCTTCATACCTTAACGGTGTCTCAATACCGATCGATGGAGGACTCATGAAATCAATATTCTAA

Upstream 100 bases:

>100_bases
GCACTATAGCTACTATAGATACTAAGAGGTCGTCTTGCACAATGACTAATATATTAATATTTTATTAACTAGTATTCGAA
AGTCTTTCTAGGTGAATATT

Downstream 100 bases:

>100_bases
AATAAAGCCACGGGTTTCATAGATCTCCGGAGTTAACAAGGTATTCCAGCACGGGGTCAGCTATTTTATACTCGTTATTT
GTTTTCACCACTAAGCCATA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MGIVEGLRVLVTASTRGLGRGAAEALLEEGAKVVINGRSRDNVEKTLGELKSRFGDRVHGVAADLTVRGDVYRLVDEAVK
FLGGLDSIIYITGPPRPGTFQEIREDEWEYNARLLVFNAIWIVNASLPYLRKSSNPSIIFSTSLAVKEPIDILALSNVLR
LSIHGLVKTLAKELGREGIRVNAVMPGYIETDRIRKLIEDRARRGNKSYEEAYREFVSDIPLGRLGSPIEYGRVIVFLAS
RYASYLNGVSIPIDGGLMKSIF

Sequences:

>Translated_262_residues
MGIVEGLRVLVTASTRGLGRGAAEALLEEGAKVVINGRSRDNVEKTLGELKSRFGDRVHGVAADLTVRGDVYRLVDEAVK
FLGGLDSIIYITGPPRPGTFQEIREDEWEYNARLLVFNAIWIVNASLPYLRKSSNPSIIFSTSLAVKEPIDILALSNVLR
LSIHGLVKTLAKELGREGIRVNAVMPGYIETDRIRKLIEDRARRGNKSYEEAYREFVSDIPLGRLGSPIEYGRVIVFLAS
RYASYLNGVSIPIDGGLMKSIF
>Mature_261_residues
GIVEGLRVLVTASTRGLGRGAAEALLEEGAKVVINGRSRDNVEKTLGELKSRFGDRVHGVAADLTVRGDVYRLVDEAVKF
LGGLDSIIYITGPPRPGTFQEIREDEWEYNARLLVFNAIWIVNASLPYLRKSSNPSIIFSTSLAVKEPIDILALSNVLRL
SIHGLVKTLAKELGREGIRVNAVMPGYIETDRIRKLIEDRARRGNKSYEEAYREFVSDIPLGRLGSPIEYGRVIVFLASR
YASYLNGVSIPIDGGLMKSIF

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=32.6612903225806, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI5031737, Length=255, Percent_Identity=30.5882352941176, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=32.2709163346614, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=31.7708333333333, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI66933014, Length=258, Percent_Identity=29.4573643410853, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=25.0965250965251, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=24.2914979757085, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI4503301, Length=228, Percent_Identity=25, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI126723191, Length=176, Percent_Identity=31.25, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI15277342, Length=259, Percent_Identity=27.7992277992278, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI32455239, Length=219, Percent_Identity=25.1141552511416, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI5031765, Length=219, Percent_Identity=25.1141552511416, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI59889578, Length=239, Percent_Identity=28.0334728033473, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI87082100, Length=261, Percent_Identity=31.4176245210728, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=26.8774703557312, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789208, Length=258, Percent_Identity=27.906976744186, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786812, Length=253, Percent_Identity=26.4822134387352, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1790717, Length=262, Percent_Identity=24.8091603053435, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789378, Length=259, Percent_Identity=28.1853281853282, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=25.2918287937743, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788459, Length=250, Percent_Identity=26.4, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082160, Length=255, Percent_Identity=23.1372549019608, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=30.4347826086957, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=32.1705426356589, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=29.2134831460674, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17562904, Length=256, Percent_Identity=28.125, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=259, Percent_Identity=29.7297297297297, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=27.9850746268657, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17508651, Length=254, Percent_Identity=30.7086614173228, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=28.7878787878788, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25147288, Length=262, Percent_Identity=22.5190839694656, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=27.8625954198473, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=27.8625954198473, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=262, Percent_Identity=28.6259541984733, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=259, Percent_Identity=27.4131274131274, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=256, Percent_Identity=24.609375, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=27.6923076923077, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=25.1968503937008, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=257, Percent_Identity=26.8482490272374, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=26.8199233716475, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=27.8625954198473, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=265, Percent_Identity=23.7735849056604, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=29.5880149812734, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=255, Percent_Identity=27.4509803921569, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=252, Percent_Identity=23.4126984126984, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=269, Percent_Identity=27.5092936802974, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17536651, Length=257, Percent_Identity=25.6809338521401, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322226, Length=188, Percent_Identity=28.7234042553192, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324126, Length=258, Percent_Identity=26.7441860465116, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21355319, Length=258, Percent_Identity=34.1085271317829, Blast_Score=130, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24639444, Length=262, Percent_Identity=29.3893129770992, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=28.1124497991968, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644339, Length=258, Percent_Identity=28.2945736434109, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=27.7777777777778, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24644337, Length=205, Percent_Identity=27.8048780487805, Blast_Score=74, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 28949; Mature: 28818

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIVEGLRVLVTASTRGLGRGAAEALLEEGAKVVINGRSRDNVEKTLGELKSRFGDRVHG
CCHHHHHHEEEEECCCCCCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCHHHC
VAADLTVRGDVYRLVDEAVKFLGGLDSIIYITGPPRPGTFQEIREDEWEYNARLLVFNAI
EEEEEEECHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHCCCCCCCCEEEEEEEE
WIVNASLPYLRKSSNPSIIFSTSLAVKEPIDILALSNVLRLSIHGLVKTLAKELGREGIR
EEEECCCHHHCCCCCCCEEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
VNAVMPGYIETDRIRKLIEDRARRGNKSYEEAYREFVSDIPLGRLGSPIEYGRVIVFLAS
EEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
RYASYLNGVSIPIDGGLMKSIF
HHHHHHCCCCCCCCCCHHHHCC
>Mature Secondary Structure 
GIVEGLRVLVTASTRGLGRGAAEALLEEGAKVVINGRSRDNVEKTLGELKSRFGDRVHG
CHHHHHHEEEEECCCCCCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCHHHC
VAADLTVRGDVYRLVDEAVKFLGGLDSIIYITGPPRPGTFQEIREDEWEYNARLLVFNAI
EEEEEEECHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHCCCCCCCCEEEEEEEE
WIVNASLPYLRKSSNPSIIFSTSLAVKEPIDILALSNVLRLSIHGLVKTLAKELGREGIR
EEEECCCHHHCCCCCCCEEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
VNAVMPGYIETDRIRKLIEDRARRGNKSYEEAYREFVSDIPLGRLGSPIEYGRVIVFLAS
EEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
RYASYLNGVSIPIDGGLMKSIF
HHHHHHCCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]