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The map label for this gene is truD [H]

Identifier: 218884386

GI number: 218884386

Start: 1019101

End: 1020213

Strand: Reverse

Name: truD [H]

Synonym: DKAM_1075

Alternate gene names: 218884386

Gene position: 1020213-1019101 (Counterclockwise)

Preceding gene: 218884387

Following gene: 218884383

Centisome position: 74.73

GC content: 42.95

Gene sequence:

>1113_bases
ATGGATTCAGACACTGGGCGGATATATCCACATCCATTGGACTACGTATCCGGGTTGAAATATTCTTTAACAAGCCTCTC
GGTGAATCATGAATATAGAATAACGCCTTCAAGCTTTATAGTCCGTGAAGTCATTGATGAAGGATACCTGGTTAAAAGAG
TGGATCTCCATGGTAGGGAAGGATATATTGTTGTAAGGGTTGTAAAGAGAGGTCTTGATACCTTTGAGGCCCTAAGAATA
CTCTCGAGGAAGCTAGATATCCCGGTTGAGAATATACATTTCCATGGATTAAAGGATAAGAACGCGACTACCACTTCATA
CTTCTACATTAAGAGACTGCTGGTGGATGAGAGGATTTTCCCTATACAGGGAGACAAAGCGGTTTTCGAGATAGCTGGAT
ACACGAGGTTTAAGCCGGGCAGGGAAATATTCAAGGGCAATGAGTTTGAAGTACTCATCCAAGGCCTTGATGAGCGTCAG
CAAGAAGTCATGAAAAGGATCCTCGAGCTGATCAGTAGGCATGGGCTCCCGGCCTACTATGGATACCAGAGATTTGGTGT
AAAGAGGTATAATACACATTTACTAGGTAAATACGTCGTAAAAAGACGTGAGAACTGTTTCTCAAGAATTCTTCTTGATA
CCATGTATCCTGGGGAGGATTTGGAAGCCATAGTAAAAAGGATAAGGAGGGATTTCACCGGCTTCTACTATGAGGGTAGA
TATGTTAGGGCTGGATACAACGGCTTAGGGTTGAAGAATGTTCTCAGGGCTCTTAACGAGATAATTATTGATGCGTACGC
CGGATACCTGTATAACTTATTACTCAATAAGATAATTGAGGAGAAGGGATTCGTGGACCTCGATAAGGAATACCCTATGC
CCGGCTGTATTGAAAGCGTTGAATTATATAGTGGTATATTCAGCGAGGAAGGGCTCACGCTAGAGGAGGCGAGGAGTCTT
CCATGCTATTATAGGAATGGGTTGTTCAAGCCGTTGAACACACGGATGTCTTGTGCTGGTGATGTATGTAGATTAGTGTT
TATGTTGGAACCTGGGTTATACGCTACGATTGTACTGAGGGAGTTATTTAAGGAGAAGCTAGTCTTAAGCTAG

Upstream 100 bases:

>100_bases
ACGGCTGTAGCTATAGGTCCAGCGCCCGATGATAGGGTTGACAAGCTAACAGGTGGCTTAAAGCTTCTGTGATGGAATTA
TTTAAAAGAGGCCCCCTATA

Downstream 100 bases:

>100_bases
ATTTATTCAAAAATTATTCGGGTTTCAACACCGAGCAGGCTTGATAATAGTTTCTCATATTCCTCCCTGTTTCTCCCTAA
TATCCTTCTATCTCTCTTTG

Product: tRNA pseudouridine synthase D

Products: NA

Alternate protein names: tRNA pseudouridylate synthase D; tRNA-uridine isomerase D [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MDSDTGRIYPHPLDYVSGLKYSLTSLSVNHEYRITPSSFIVREVIDEGYLVKRVDLHGREGYIVVRVVKRGLDTFEALRI
LSRKLDIPVENIHFHGLKDKNATTTSYFYIKRLLVDERIFPIQGDKAVFEIAGYTRFKPGREIFKGNEFEVLIQGLDERQ
QEVMKRILELISRHGLPAYYGYQRFGVKRYNTHLLGKYVVKRRENCFSRILLDTMYPGEDLEAIVKRIRRDFTGFYYEGR
YVRAGYNGLGLKNVLRALNEIIIDAYAGYLYNLLLNKIIEEKGFVDLDKEYPMPGCIESVELYSGIFSEEGLTLEEARSL
PCYYRNGLFKPLNTRMSCAGDVCRLVFMLEPGLYATIVLRELFKEKLVLS

Sequences:

>Translated_370_residues
MDSDTGRIYPHPLDYVSGLKYSLTSLSVNHEYRITPSSFIVREVIDEGYLVKRVDLHGREGYIVVRVVKRGLDTFEALRI
LSRKLDIPVENIHFHGLKDKNATTTSYFYIKRLLVDERIFPIQGDKAVFEIAGYTRFKPGREIFKGNEFEVLIQGLDERQ
QEVMKRILELISRHGLPAYYGYQRFGVKRYNTHLLGKYVVKRRENCFSRILLDTMYPGEDLEAIVKRIRRDFTGFYYEGR
YVRAGYNGLGLKNVLRALNEIIIDAYAGYLYNLLLNKIIEEKGFVDLDKEYPMPGCIESVELYSGIFSEEGLTLEEARSL
PCYYRNGLFKPLNTRMSCAGDVCRLVFMLEPGLYATIVLRELFKEKLVLS
>Mature_370_residues
MDSDTGRIYPHPLDYVSGLKYSLTSLSVNHEYRITPSSFIVREVIDEGYLVKRVDLHGREGYIVVRVVKRGLDTFEALRI
LSRKLDIPVENIHFHGLKDKNATTTSYFYIKRLLVDERIFPIQGDKAVFEIAGYTRFKPGREIFKGNEFEVLIQGLDERQ
QEVMKRILELISRHGLPAYYGYQRFGVKRYNTHLLGKYVVKRRENCFSRILLDTMYPGEDLEAIVKRIRRDFTGFYYEGR
YVRAGYNGLGLKNVLRALNEIIIDAYAGYLYNLLLNKIIEEKGFVDLDKEYPMPGCIESVELYSGIFSEEGLTLEEARSL
PCYYRNGLFKPLNTRMSCAGDVCRLVFMLEPGLYATIVLRELFKEKLVLS

Specific function: Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs [H]

COG id: COG0585

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRUD domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR001656
- InterPro:   IPR020119
- InterPro:   IPR011760 [H]

Pfam domain/function: PF01142 TruD [H]

EC number: NA

Molecular weight: Translated: 42970; Mature: 42970

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS50984 TRUD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSDTGRIYPHPLDYVSGLKYSLTSLSVNHEYRITPSSFIVREVIDEGYLVKRVDLHGRE
CCCCCCCCCCCCHHHHCCCHHHHEEEEECCEEEECHHHHHHHHHHCCCCEEEEEECCCCC
GYIVVRVVKRGLDTFEALRILSRKLDIPVENIHFHGLKDKNATTTSYFYIKRLLVDERIF
CEEEHHHHHHCCHHHHHHHHHHHHCCCCHHCCEECCCCCCCCCHHHHHHHHHHHHHCCCC
PIQGDKAVFEIAGYTRFKPGREIFKGNEFEVLIQGLDERQQEVMKRILELISRHGLPAYY
CCCCCCEEEEECCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
GYQRFGVKRYNTHLLGKYVVKRRENCFSRILLDTMYPGEDLEAIVKRIRRDFTGFYYEGR
CHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEECCE
YVRAGYNGLGLKNVLRALNEIIIDAYAGYLYNLLLNKIIEEKGFVDLDKEYPMPGCIESV
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHH
ELYSGIFSEEGLTLEEARSLPCYYRNGLFKPLNTRMSCAGDVCRLVFMLEPGLYATIVLR
HHHHHHHCCCCCCHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
ELFKEKLVLS
HHHHHHHCCC
>Mature Secondary Structure
MDSDTGRIYPHPLDYVSGLKYSLTSLSVNHEYRITPSSFIVREVIDEGYLVKRVDLHGRE
CCCCCCCCCCCCHHHHCCCHHHHEEEEECCEEEECHHHHHHHHHHCCCCEEEEEECCCCC
GYIVVRVVKRGLDTFEALRILSRKLDIPVENIHFHGLKDKNATTTSYFYIKRLLVDERIF
CEEEHHHHHHCCHHHHHHHHHHHHCCCCHHCCEECCCCCCCCCHHHHHHHHHHHHHCCCC
PIQGDKAVFEIAGYTRFKPGREIFKGNEFEVLIQGLDERQQEVMKRILELISRHGLPAYY
CCCCCCEEEEECCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
GYQRFGVKRYNTHLLGKYVVKRRENCFSRILLDTMYPGEDLEAIVKRIRRDFTGFYYEGR
CHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEECCE
YVRAGYNGLGLKNVLRALNEIIIDAYAGYLYNLLLNKIIEEKGFVDLDKEYPMPGCIESV
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHH
ELYSGIFSEEGLTLEEARSLPCYYRNGLFKPLNTRMSCAGDVCRLVFMLEPGLYATIVLR
HHHHHHHCCCCCCHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
ELFKEKLVLS
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]