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The map label for this gene is pth [H]

Identifier: 218884387

GI number: 218884387

Start: 1020242

End: 1020589

Strand: Reverse

Name: pth [H]

Synonym: DKAM_1076

Alternate gene names: 218884387

Gene position: 1020589-1020242 (Counterclockwise)

Preceding gene: 218884391

Following gene: 218884386

Centisome position: 74.76

GC content: 46.84

Gene sequence:

>348_bases
ATGAAACAGGTTATAGTGGTTAGAAGCGACCTGGAGATGAGTAAGGGTAAGATAGCTGCCCAGGTCGCCCATGCATCAGT
TATAGCTGCGTTCGAAGCCTATTATAACCATAGAGAGTGGTTTAATGAGTGGTGGAATAGTGGGCAGAAGAAGATAGTTG
TTAAGGTAAGAGGGGAGGAAGAGTTGGTGAAGATATATATGGAGGCAATATCTAATGGGTTACCTGCCTCAATAGTGAGG
GATGCTGGGTTGACAGAGCTTCCCCCAGGCACAATAACGGCTGTAGCTATAGGTCCAGCGCCCGATGATAGGGTTGACAA
GCTAACAGGTGGCTTAAAGCTTCTGTGA

Upstream 100 bases:

>100_bases
CTATTGATTATGGTTAATGGGATTAAAAATATTAGTCCCTTATTTCCCAATTAGAGCCCATGCTGTGCCTGGTGAGTTAA
GTTAGTGTAGGGGTTAACAT

Downstream 100 bases:

>100_bases
TGGAATTATTTAAAAGAGGCCCCCTATAATGGATTCAGACACTGGGCGGATATATCCACATCCATTGGACTACGTATCCG
GGTTGAAATATTCTTTAACA

Product: peptidyl-tRNA hydrolase

Products: NA

Alternate protein names: PTH [H]

Number of amino acids: Translated: 115; Mature: 115

Protein sequence:

>115_residues
MKQVIVVRSDLEMSKGKIAAQVAHASVIAAFEAYYNHREWFNEWWNSGQKKIVVKVRGEEELVKIYMEAISNGLPASIVR
DAGLTELPPGTITAVAIGPAPDDRVDKLTGGLKLL

Sequences:

>Translated_115_residues
MKQVIVVRSDLEMSKGKIAAQVAHASVIAAFEAYYNHREWFNEWWNSGQKKIVVKVRGEEELVKIYMEAISNGLPASIVR
DAGLTELPPGTITAVAIGPAPDDRVDKLTGGLKLL
>Mature_115_residues
MKQVIVVRSDLEMSKGKIAAQVAHASVIAAFEAYYNHREWFNEWWNSGQKKIVVKVRGEEELVKIYMEAISNGLPASIVR
DAGLTELPPGTITAVAIGPAPDDRVDKLTGGLKLL

Specific function: The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis [H]

COG id: COG1990

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTH2 family [H]

Homologues:

Organism=Homo sapiens, GI7706351, Length=113, Percent_Identity=45.1327433628319, Blast_Score=103, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17558188, Length=117, Percent_Identity=40.1709401709402, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319414, Length=121, Percent_Identity=38.8429752066116, Blast_Score=88, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24646438, Length=117, Percent_Identity=42.7350427350427, Blast_Score=93, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281376919, Length=115, Percent_Identity=43.4782608695652, Blast_Score=92, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24644665, Length=115, Percent_Identity=43.4782608695652, Blast_Score=92, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002833 [H]

Pfam domain/function: PF01981 PTH2 [H]

EC number: =3.1.1.29 [H]

Molecular weight: Translated: 12618; Mature: 12618

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQVIVVRSDLEMSKGKIAAQVAHASVIAAFEAYYNHREWFNEWWNSGQKKIVVKVRGEE
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHH
ELVKIYMEAISNGLPASIVRDAGLTELPPGTITAVAIGPAPDDRVDKLTGGLKLL
HHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHCCCEECC
>Mature Secondary Structure
MKQVIVVRSDLEMSKGKIAAQVAHASVIAAFEAYYNHREWFNEWWNSGQKKIVVKVRGEE
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHH
ELVKIYMEAISNGLPASIVRDAGLTELPPGTITAVAIGPAPDDRVDKLTGGLKLL
HHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA