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The map label for this gene is tldD [C]

Identifier: 218884244

GI number: 218884244

Start: 886162

End: 887595

Strand: Direct

Name: tldD [C]

Synonym: DKAM_0933

Alternate gene names: 218884244

Gene position: 886162-887595 (Clockwise)

Preceding gene: 218884242

Following gene: 218884245

Centisome position: 64.91

GC content: 48.26

Gene sequence:

>1434_bases
TTGCTGGATCTTGTTGAATACGCGGTTAAATTAGCCAGCGATCTAGGCGCATCCTATGGTGAAGCAAGGTACCACGGGAT
CAACGGGTTCACTATTTATACTAGAAATGGAAATGTAATGGGCTCCGGCATTACGAGCCGTAGAGGTATAGCTGTCAGAG
TCGTAGTAAACGGGGCCCTCGGGTTCGCTGCAACACCCGAGCTAACTAGGGATGGGGTAAGAAAGACTGTGGAGAAAGCC
GTCTCATTAGCGAAGGCAGTATCTCAACTCATGAAGAAGCCGTTGAAACAAGACGACTCAAGGCTTGGAAGAGCCAGGTA
CTCCGTTGTAGCTAGAAAACCATTTGACTCAATACCGCTGGATGAAAAAGTCAACTATATGACGGGGCTGTGGAGAAACA
TACAGGGCTCCACTAAGGAGGCACGTATCCCCGTGTTAACTGTTACATATAACGAGTGGACTGAGGAGAAGATAATAGTC
AATAGTGATGGCGGATACGTGGAGTCAAGTATTCCTAGGATAACCATGTATTACAACATGGTGGTGACGTTGCCTGCGAA
GGGCAGTCTACAGAGGTGGGAGCAATTGGGGGGCTCCGGTGGATTAGAGCTACTTGAGAAGTGGAGGCTCCATGAGAAGC
TGCCTGAGGAAGTAGGTAGATACGAAGAAATCCTCTTCAAGGCTCTGCCACCCCCCACAGACCCGGTAGACGTTATCGTG
GGAAGCGAGATCGTCGGGCTAGTTGTCCATGAGTCATGCGGGCACCCGAGTGAAGCGGATAGAATAATGGGCCGGGAAGC
AGCCCAGGCTGGGAAAAGCTTCATAAAGCCAGGTATGCAGGGTTCCCGGATAGGTAATGAATACGCTACAGTCATAGATG
ACCCAACCATACCTGGAAGCTATGGTTTCTACCTATACGATGATGAAGCCGTTCCAGCTAGAGCTAGATACCTCTACAAA
GAGGGAGTCATATACGAGCACCTGCAAAACAGGTTCACAGCCCCATTCTATAATACTAGAAGTAATGGAGCAGCTAGAGC
CATGGACTACGCCAGTGAACCTATTATTAGAATGGCAAATACGTATTTAAAACCAGGGGACATGAGCTTTGAAGAGCTCT
TAGAATCGGTTAAGAGAGGAGTATATATTAAGTCTTACATGGAGTGGAACATCGATGATGAACGGTGGAGTCAGAGGTAT
GTCGGGCTGGAGGCATACATGATAGAGAATGGAGAGTTAAAGGGATATGTTAGAAACCCGGTGCTGGAGGTTACCACGAA
GTCGTTCTATAGTAGCATAGATGGAGTAGATAGAAACCTGGAATTCTACGCTGGTACATGCGGTAAAGGCGAACCCTCCC
AGGGCGTACCCGTATGGTTTGGAGGCCCGAATGTGAAGCTTAAGAATATAAGGCTTAGAAGTACTGTGGGGTGA

Upstream 100 bases:

>100_bases
TTCCCCGCATCTATTTGGGAATGCATCTTTTATTTGTGGAATAGTCGAGGGGATAAAGTTTTTTATTCTGAGAACAATAT
ATGGTTCTTTGGTGTAAACA

Downstream 100 bases:

>100_bases
TTTGAATGGAGATATATAAGAGGATATTAAAGGAGGCCCTTGATAAGGGGTTCCAGGAGGCAATCGTTAGAGTGCTTGAA
TCCGAGAGAACGATGACCAA

Product: peptidase U62, modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MLDLVEYAVKLASDLGASYGEARYHGINGFTIYTRNGNVMGSGITSRRGIAVRVVVNGALGFAATPELTRDGVRKTVEKA
VSLAKAVSQLMKKPLKQDDSRLGRARYSVVARKPFDSIPLDEKVNYMTGLWRNIQGSTKEARIPVLTVTYNEWTEEKIIV
NSDGGYVESSIPRITMYYNMVVTLPAKGSLQRWEQLGGSGGLELLEKWRLHEKLPEEVGRYEEILFKALPPPTDPVDVIV
GSEIVGLVVHESCGHPSEADRIMGREAAQAGKSFIKPGMQGSRIGNEYATVIDDPTIPGSYGFYLYDDEAVPARARYLYK
EGVIYEHLQNRFTAPFYNTRSNGAARAMDYASEPIIRMANTYLKPGDMSFEELLESVKRGVYIKSYMEWNIDDERWSQRY
VGLEAYMIENGELKGYVRNPVLEVTTKSFYSSIDGVDRNLEFYAGTCGKGEPSQGVPVWFGGPNVKLKNIRLRSTVG

Sequences:

>Translated_477_residues
MLDLVEYAVKLASDLGASYGEARYHGINGFTIYTRNGNVMGSGITSRRGIAVRVVVNGALGFAATPELTRDGVRKTVEKA
VSLAKAVSQLMKKPLKQDDSRLGRARYSVVARKPFDSIPLDEKVNYMTGLWRNIQGSTKEARIPVLTVTYNEWTEEKIIV
NSDGGYVESSIPRITMYYNMVVTLPAKGSLQRWEQLGGSGGLELLEKWRLHEKLPEEVGRYEEILFKALPPPTDPVDVIV
GSEIVGLVVHESCGHPSEADRIMGREAAQAGKSFIKPGMQGSRIGNEYATVIDDPTIPGSYGFYLYDDEAVPARARYLYK
EGVIYEHLQNRFTAPFYNTRSNGAARAMDYASEPIIRMANTYLKPGDMSFEELLESVKRGVYIKSYMEWNIDDERWSQRY
VGLEAYMIENGELKGYVRNPVLEVTTKSFYSSIDGVDRNLEFYAGTCGKGEPSQGVPVWFGGPNVKLKNIRLRSTVG
>Mature_477_residues
MLDLVEYAVKLASDLGASYGEARYHGINGFTIYTRNGNVMGSGITSRRGIAVRVVVNGALGFAATPELTRDGVRKTVEKA
VSLAKAVSQLMKKPLKQDDSRLGRARYSVVARKPFDSIPLDEKVNYMTGLWRNIQGSTKEARIPVLTVTYNEWTEEKIIV
NSDGGYVESSIPRITMYYNMVVTLPAKGSLQRWEQLGGSGGLELLEKWRLHEKLPEEVGRYEEILFKALPPPTDPVDVIV
GSEIVGLVVHESCGHPSEADRIMGREAAQAGKSFIKPGMQGSRIGNEYATVIDDPTIPGSYGFYLYDDEAVPARARYLYK
EGVIYEHLQNRFTAPFYNTRSNGAARAMDYASEPIIRMANTYLKPGDMSFEELLESVKRGVYIKSYMEWNIDDERWSQRY
VGLEAYMIENGELKGYVRNPVLEVTTKSFYSSIDGVDRNLEFYAGTCGKGEPSQGVPVWFGGPNVKLKNIRLRSTVG

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=438, Percent_Identity=24.2009132420091, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 53220; Mature: 53220

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLVEYAVKLASDLGASYGEARYHGINGFTIYTRNGNVMGSGITSRRGIAVRVVVNGAL
CCHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEEECCCEEECCCCCCCCEEEEEEEECCC
GFAATPELTRDGVRKTVEKAVSLAKAVSQLMKKPLKQDDSRLGRARYSVVARKPFDSIPL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEECCCCCCCC
DEKVNYMTGLWRNIQGSTKEARIPVLTVTYNEWTEEKIIVNSDGGYVESSIPRITMYYNM
CHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCEEECCCCEEEEEEEE
VVTLPAKGSLQRWEQLGGSGGLELLEKWRLHEKLPEEVGRYEEILFKALPPPTDPVDVIV
EEEECCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
GSEIVGLVVHESCGHPSEADRIMGREAAQAGKSFIKPGMQGSRIGNEYATVIDDPTIPGS
CCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCC
YGFYLYDDEAVPARARYLYKEGVIYEHLQNRFTAPFYNTRSNGAARAMDYASEPIIRMAN
CCEEEECCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCHHHHHHH
TYLKPGDMSFEELLESVKRGVYIKSYMEWNIDDERWSQRYVGLEAYMIENGELKGYVRNP
HCCCCCCCCHHHHHHHHHCCEEEEEHEECCCCHHHHHHHHCCEEEEEEECCCCCEEECCC
VLEVTTKSFYSSIDGVDRNLEFYAGTCGKGEPSQGVPVWFGGPNVKLKNIRLRSTVG
CHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCEEEECCCCEEEEEEEECCCCC
>Mature Secondary Structure
MLDLVEYAVKLASDLGASYGEARYHGINGFTIYTRNGNVMGSGITSRRGIAVRVVVNGAL
CCHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEEECCCEEECCCCCCCCEEEEEEEECCC
GFAATPELTRDGVRKTVEKAVSLAKAVSQLMKKPLKQDDSRLGRARYSVVARKPFDSIPL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEECCCCCCCC
DEKVNYMTGLWRNIQGSTKEARIPVLTVTYNEWTEEKIIVNSDGGYVESSIPRITMYYNM
CHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCEEECCCCEEEEEEEE
VVTLPAKGSLQRWEQLGGSGGLELLEKWRLHEKLPEEVGRYEEILFKALPPPTDPVDVIV
EEEECCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
GSEIVGLVVHESCGHPSEADRIMGREAAQAGKSFIKPGMQGSRIGNEYATVIDDPTIPGS
CCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCC
YGFYLYDDEAVPARARYLYKEGVIYEHLQNRFTAPFYNTRSNGAARAMDYASEPIIRMAN
CCEEEECCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCHHHHHHH
TYLKPGDMSFEELLESVKRGVYIKSYMEWNIDDERWSQRYVGLEAYMIENGELKGYVRNP
HCCCCCCCCHHHHHHHHHCCEEEEEHEECCCCHHHHHHHHCCEEEEEEECCCCCEEECCC
VLEVTTKSFYSSIDGVDRNLEFYAGTCGKGEPSQGVPVWFGGPNVKLKNIRLRSTVG
CHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCEEEECCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]