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The map label for this gene is pncB [H]

Identifier: 218884153

GI number: 218884153

Start: 810155

End: 811330

Strand: Direct

Name: pncB [H]

Synonym: DKAM_0842

Alternate gene names: 218884153

Gene position: 810155-811330 (Clockwise)

Preceding gene: 218884152

Following gene: 218884155

Centisome position: 59.34

GC content: 47.02

Gene sequence:

>1176_bases
ATGAGGTTCTATATAGCCTGCGAGAACGAGATACTGGATGGATCCGCAACAGACGTGTACTTCACGAGGACCTATAAGAT
ACTTAAAGCCAAGGGTGTCAGGAAGAAGGTTAGGATGGAATTCCATGTAATGAGGCTGCCCAAGGGCTATGAATGGGCTG
TATATGCTGGACTCGAGGAGGTACTTTACTTACTGAAGGATAAGCCGGTGACAGTATACTCTATGCCTGAGGGAACACTG
TTTAAGGCTGGCGAGCCATTACTTATCATAGAGGGCTACTATGATGACTTCGCATTATACGAGACAGCCGTGCTTGGCAT
ACTTAGACACTACTCGAGTATAGCTAGTAAGGCGGCACGTATTAAGAGGCTTGCAATGGATAAAACAATACTCTTCTTCG
GGCTTAGAGCCGTCCACCCTGTAATAGCTCCTATGGTTGATCGAGCAGCATACATCGGTGGGGCTGATGCCGTCTCAGGG
GTTCTAAGCGAGAAATATTTGGGGATTAAGCCATCGGGGACGATGCCTCATGCATTAATACTGGTCCTTGGCGATCAGAG
AGAGGCGTGGAAAGCATTTGATGATGTGGTAGAGCCTAGTGTACCCAGGATTATGCTTGTAGATACGTTATTCGATGAAC
GTGAGGAAGCATTGATGGCTGCCAAATTATTGGGTGATAGGCTATATGGCGTTAGATTGGATACGCCTAGCAGTAGACGC
GGCGACATGAGGCAAATAGTGGAAGAGGTTAGATGGACCCTCGATGTAAACGGGTTTAAACACGTTAAAATAGTTGTAAG
CGGAGGGCTGGATGAAAAGGAAATCGTGAGGCTCAGAGACGTCGTAGACGCCTTCGGTGTTGGGACAAGTATATCGATGC
CCCCCAGCGTCGACATCAGTGCTGATATTGTTGAGGTATACGATAACGATGCATGGAGACCCTTCACAAAGAGGGGTAAG
CTACCTGGAGCCAAACAGGTATTCAGGAAGAGGCCGGGGTTAAATGACATTGTTACACTAATGGAGAACCATGGTGAAAT
ACCCAGTGGATATACCCCGCTTCTAGTTAAATACATTGATAATGGTGAACTGGTAAGGAAGCCACCTACTATAGAAGACA
TTAGGAGATACGTTATCGAGCAGCTTAGAGAGGTACCAGAGCCCTCTCTCGAATAG

Upstream 100 bases:

>100_bases
GGGAGGATAGCTAGAGGAACTTGGCAGAATATATTTTTCGTTGAAATGGATGGCCCACGTTCAAATAGGGAGGTTGTGAT
AACAGTTATTGGTGAGTGAT

Downstream 100 bases:

>100_bases
CCTTACTGCCTAAGCCTCCTAATCAACCTGCTTAACTCGGAGAGATTATTAATAGCTATGTATTTTTCAACCGGATCAAT
CCATGGCGTATCATAGAGGG

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MRFYIACENEILDGSATDVYFTRTYKILKAKGVRKKVRMEFHVMRLPKGYEWAVYAGLEEVLYLLKDKPVTVYSMPEGTL
FKAGEPLLIIEGYYDDFALYETAVLGILRHYSSIASKAARIKRLAMDKTILFFGLRAVHPVIAPMVDRAAYIGGADAVSG
VLSEKYLGIKPSGTMPHALILVLGDQREAWKAFDDVVEPSVPRIMLVDTLFDEREEALMAAKLLGDRLYGVRLDTPSSRR
GDMRQIVEEVRWTLDVNGFKHVKIVVSGGLDEKEIVRLRDVVDAFGVGTSISMPPSVDISADIVEVYDNDAWRPFTKRGK
LPGAKQVFRKRPGLNDIVTLMENHGEIPSGYTPLLVKYIDNGELVRKPPTIEDIRRYVIEQLREVPEPSLE

Sequences:

>Translated_391_residues
MRFYIACENEILDGSATDVYFTRTYKILKAKGVRKKVRMEFHVMRLPKGYEWAVYAGLEEVLYLLKDKPVTVYSMPEGTL
FKAGEPLLIIEGYYDDFALYETAVLGILRHYSSIASKAARIKRLAMDKTILFFGLRAVHPVIAPMVDRAAYIGGADAVSG
VLSEKYLGIKPSGTMPHALILVLGDQREAWKAFDDVVEPSVPRIMLVDTLFDEREEALMAAKLLGDRLYGVRLDTPSSRR
GDMRQIVEEVRWTLDVNGFKHVKIVVSGGLDEKEIVRLRDVVDAFGVGTSISMPPSVDISADIVEVYDNDAWRPFTKRGK
LPGAKQVFRKRPGLNDIVTLMENHGEIPSGYTPLLVKYIDNGELVRKPPTIEDIRRYVIEQLREVPEPSLE
>Mature_391_residues
MRFYIACENEILDGSATDVYFTRTYKILKAKGVRKKVRMEFHVMRLPKGYEWAVYAGLEEVLYLLKDKPVTVYSMPEGTL
FKAGEPLLIIEGYYDDFALYETAVLGILRHYSSIASKAARIKRLAMDKTILFFGLRAVHPVIAPMVDRAAYIGGADAVSG
VLSEKYLGIKPSGTMPHALILVLGDQREAWKAFDDVVEPSVPRIMLVDTLFDEREEALMAAKLLGDRLYGVRLDTPSSRR
GDMRQIVEEVRWTLDVNGFKHVKIVVSGGLDEKEIVRLRDVVDAFGVGTSISMPPSVDISADIVEVYDNDAWRPFTKRGK
LPGAKQVFRKRPGLNDIVTLMENHGEIPSGYTPLLVKYIDNGELVRKPPTIEDIRRYVIEQLREVPEPSLE

Specific function: Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN) [H]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR006405
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 44085; Mature: 44085

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFYIACENEILDGSATDVYFTRTYKILKAKGVRKKVRMEFHVMRLPKGYEWAVYAGLEE
CEEEEEECCCCCCCCCCEEEEEHHHHHHHHCCHHHHHHHHEEEEECCCCCCEEEHHCHHH
VLYLLKDKPVTVYSMPEGTLFKAGEPLLIIEGYYDDFALYETAVLGILRHYSSIASKAAR
HHHHHCCCCEEEEECCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IKRLAMDKTILFFGLRAVHPVIAPMVDRAAYIGGADAVSGVLSEKYLGIKPSGTMPHALI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCEEEE
LVLGDQREAWKAFDDVVEPSVPRIMLVDTLFDEREEALMAAKLLGDRLYGVRLDTPSSRR
EEECCCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCC
GDMRQIVEEVRWTLDVNGFKHVKIVVSGGLDEKEIVRLRDVVDAFGVGTSISMPPSVDIS
CHHHHHHHHHHHEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ADIVEVYDNDAWRPFTKRGKLPGAKQVFRKRPGLNDIVTLMENHGEIPSGYTPLLVKYID
HHHHEECCCCCCCCHHHCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEEEEC
NGELVRKPPTIEDIRRYVIEQLREVPEPSLE
CCCEEECCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRFYIACENEILDGSATDVYFTRTYKILKAKGVRKKVRMEFHVMRLPKGYEWAVYAGLEE
CEEEEEECCCCCCCCCCEEEEEHHHHHHHHCCHHHHHHHHEEEEECCCCCCEEEHHCHHH
VLYLLKDKPVTVYSMPEGTLFKAGEPLLIIEGYYDDFALYETAVLGILRHYSSIASKAAR
HHHHHCCCCEEEEECCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IKRLAMDKTILFFGLRAVHPVIAPMVDRAAYIGGADAVSGVLSEKYLGIKPSGTMPHALI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCEEEE
LVLGDQREAWKAFDDVVEPSVPRIMLVDTLFDEREEALMAAKLLGDRLYGVRLDTPSSRR
EEECCCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCC
GDMRQIVEEVRWTLDVNGFKHVKIVVSGGLDEKEIVRLRDVVDAFGVGTSISMPPSVDIS
CHHHHHHHHHHHEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ADIVEVYDNDAWRPFTKRGKLPGAKQVFRKRPGLNDIVTLMENHGEIPSGYTPLLVKYID
HHHHEECCCCCCCCHHHCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEEEEC
NGELVRKPPTIEDIRRYVIEQLREVPEPSLE
CCCEEECCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]