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The map label for this gene is aspC [H]

Identifier: 218883779

GI number: 218883779

Start: 436798

End: 437976

Strand: Reverse

Name: aspC [H]

Synonym: DKAM_0468

Alternate gene names: 218883779

Gene position: 437976-436798 (Counterclockwise)

Preceding gene: 218883780

Following gene: 218883778

Centisome position: 32.08

GC content: 48.43

Gene sequence:

>1179_bases
GTGTTAAGTCTCCCAGTCAACCCTCAGAGAGTTCTCATCGCTAAGGCAGAGGAGCTATCTAGACAGGGCGTCAAGGTATA
TAACTACACGGCTGGGCAGCCTGGCCTCCCACCGGATCGCGAGGCCCTCGAATACTTCATAGAGATGGTTAGGAAGGATC
CCTTTAAACACTTCAGATATGTATCGACACAGGGGTTGCCAGAGCTAAGGGCAGCTATCTCGGATGACTTAAAGAGGTAT
GGAGGTATAGATGTCCAGCCAAAGGACATCCTCGTGACCACTGGAGGAGCCGATGGATTAGTCCTATCGATATATACACT
CCTCGATGAAAGGGATACACTGCTACTACTTGATCCATCCTACAGCGTATACTGGGATCTCGCTAAGCTAGCCGGCTTAA
AGGTGGAGACTTGTAGACAGACCCTTGAAAACGGATTCAACCCTGATCCAGAGTGTATAAAGGAGAAGCTAGGCTCGAAG
GCTAAGGCAATACTCCTGGCCAGCCCTGATAACCCAACTAGTAGAATACTTAGCAGTGAAGTAGGGAAGACTATTGTAGA
TGTTGCCTACGAGAAGAAGGCTTGGATAATATATGACGTTGCATACAAGCACCTAGTCTATGAGGAAGAACACCTATGGC
TTGAGAAGCTTGCTCCATCCATGGATAATATAGTCGTCGTCGGCTCATTCAGTAAAGACATAGCAATACCAGGGGGTAGG
CTTGGATACGTGTACGGGTCGGGCAACACTATATCAGAGATGACTAAGCTGAAGGGTGTGCTAGGTATAGTCGCCCCCGT
ACCGATGCAGTGGATGGCATATTACTATCTCTCCCAGGGATTCAAGGAGAAATACCTCCGCGACGTGATCCCAGCGTATA
AGAGACGCCGGGACGCAGCATATGAGGCTTTCAGGAGGAACCTGCCTCATGCAAGGATACAGAAGCCCGTTGCAAGCATG
TACTTGTTCCCAGATATGTCATACTACATCAAGAAGAAGGGGTTAAGTGACGTGGAGTTCACGATGAAGCTTATAGAGGA
GAAAGGCGTTGCAATGCTACCCGGCTCTATATTCGGTGAAGCCGGTGTAAACCATCTCAGAATAACATTCGTCACAATGG
ATGAGAAAAACCTTGTTGAAGGCATAGAACGCCTCGCGGAGTTTGTTGGCGAAAGATGA

Upstream 100 bases:

>100_bases
ATTTGTGGAGTCCTGGTTAAATGTGTTTATATATTTATGGCTATATATAGATAGTATGTATAACTCTAGAGGTGTCTAGC
CGTTGAATATATCTAGACGG

Downstream 100 bases:

>100_bases
TGTATTTTAGTTCACCAGTAATCTATCCCTATAAGTAATTTTTAATATATCTCATCGTGTAGTATGTAGTTTAGCTAGGG
ATCTCTTGCTAGGGGCTTCC

Product: Aspartate aminotransferase (AspC), conjectural

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MLSLPVNPQRVLIAKAEELSRQGVKVYNYTAGQPGLPPDREALEYFIEMVRKDPFKHFRYVSTQGLPELRAAISDDLKRY
GGIDVQPKDILVTTGGADGLVLSIYTLLDERDTLLLLDPSYSVYWDLAKLAGLKVETCRQTLENGFNPDPECIKEKLGSK
AKAILLASPDNPTSRILSSEVGKTIVDVAYEKKAWIIYDVAYKHLVYEEEHLWLEKLAPSMDNIVVVGSFSKDIAIPGGR
LGYVYGSGNTISEMTKLKGVLGIVAPVPMQWMAYYYLSQGFKEKYLRDVIPAYKRRRDAAYEAFRRNLPHARIQKPVASM
YLFPDMSYYIKKKGLSDVEFTMKLIEEKGVAMLPGSIFGEAGVNHLRITFVTMDEKNLVEGIERLAEFVGER

Sequences:

>Translated_392_residues
MLSLPVNPQRVLIAKAEELSRQGVKVYNYTAGQPGLPPDREALEYFIEMVRKDPFKHFRYVSTQGLPELRAAISDDLKRY
GGIDVQPKDILVTTGGADGLVLSIYTLLDERDTLLLLDPSYSVYWDLAKLAGLKVETCRQTLENGFNPDPECIKEKLGSK
AKAILLASPDNPTSRILSSEVGKTIVDVAYEKKAWIIYDVAYKHLVYEEEHLWLEKLAPSMDNIVVVGSFSKDIAIPGGR
LGYVYGSGNTISEMTKLKGVLGIVAPVPMQWMAYYYLSQGFKEKYLRDVIPAYKRRRDAAYEAFRRNLPHARIQKPVASM
YLFPDMSYYIKKKGLSDVEFTMKLIEEKGVAMLPGSIFGEAGVNHLRITFVTMDEKNLVEGIERLAEFVGER
>Mature_392_residues
MLSLPVNPQRVLIAKAEELSRQGVKVYNYTAGQPGLPPDREALEYFIEMVRKDPFKHFRYVSTQGLPELRAAISDDLKRY
GGIDVQPKDILVTTGGADGLVLSIYTLLDERDTLLLLDPSYSVYWDLAKLAGLKVETCRQTLENGFNPDPECIKEKLGSK
AKAILLASPDNPTSRILSSEVGKTIVDVAYEKKAWIIYDVAYKHLVYEEEHLWLEKLAPSMDNIVVVGSFSKDIAIPGGR
LGYVYGSGNTISEMTKLKGVLGIVAPVPMQWMAYYYLSQGFKEKYLRDVIPAYKRRRDAAYEAFRRNLPHARIQKPVASM
YLFPDMSYYIKKKGLSDVEFTMKLIEEKGVAMLPGSIFGEAGVNHLRITFVTMDEKNLVEGIERLAEFVGER

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=399, Percent_Identity=24.5614035087719, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI169881279, Length=399, Percent_Identity=24.5614035087719, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI4507369, Length=399, Percent_Identity=23.3082706766917, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI56713256, Length=388, Percent_Identity=22.9381443298969, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI56713254, Length=388, Percent_Identity=22.9381443298969, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI4885351, Length=345, Percent_Identity=24.0579710144928, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1788722, Length=359, Percent_Identity=26.4623955431755, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1788627, Length=388, Percent_Identity=23.7113402061856, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786816, Length=336, Percent_Identity=26.1904761904762, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787710, Length=335, Percent_Identity=23.2835820895522, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788332, Length=206, Percent_Identity=25.7281553398058, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17567369, Length=389, Percent_Identity=21.8508997429306, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17567663, Length=400, Percent_Identity=25.75, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71994476, Length=374, Percent_Identity=22.192513368984, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71994472, Length=374, Percent_Identity=22.192513368984, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=403, Percent_Identity=24.317617866005, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6320317, Length=354, Percent_Identity=25.9887005649718, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573069, Length=381, Percent_Identity=22.8346456692913, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24646114, Length=381, Percent_Identity=22.8346456692913, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573067, Length=381, Percent_Identity=22.8346456692913, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573065, Length=381, Percent_Identity=22.8346456692913, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI18859735, Length=347, Percent_Identity=23.9193083573487, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44182; Mature: 44182

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLPVNPQRVLIAKAEELSRQGVKVYNYTAGQPGLPPDREALEYFIEMVRKDPFKHFRY
CCCCCCCCCEEEEEEHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCHHHHHHH
VSTQGLPELRAAISDDLKRYGGIDVQPKDILVTTGGADGLVLSIYTLLDERDTLLLLDPS
HCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEECCC
YSVYWDLAKLAGLKVETCRQTLENGFNPDPECIKEKLGSKAKAILLASPDNPTSRILSSE
CHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEEECCCCHHHHHHHHH
VGKTIVDVAYEKKAWIIYDVAYKHLVYEEEHLWLEKLAPSMDNIVVVGSFSKDIAIPGGR
HHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCC
LGYVYGSGNTISEMTKLKGVLGIVAPVPMQWMAYYYLSQGFKEKYLRDVIPAYKRRRDAA
EEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YEAFRRNLPHARIQKPVASMYLFPDMSYYIKKKGLSDVEFTMKLIEEKGVAMLPGSIFGE
HHHHHHCCCHHHHHHHHHHEEECCCHHHHHHHCCCCHHHHHHHHHHHCCCEECCCHHHHC
AGVNHLRITFVTMDEKNLVEGIERLAEFVGER
CCCCEEEEEEEEECHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLSLPVNPQRVLIAKAEELSRQGVKVYNYTAGQPGLPPDREALEYFIEMVRKDPFKHFRY
CCCCCCCCCEEEEEEHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCHHHHHHH
VSTQGLPELRAAISDDLKRYGGIDVQPKDILVTTGGADGLVLSIYTLLDERDTLLLLDPS
HCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEECCC
YSVYWDLAKLAGLKVETCRQTLENGFNPDPECIKEKLGSKAKAILLASPDNPTSRILSSE
CHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEEECCCCHHHHHHHHH
VGKTIVDVAYEKKAWIIYDVAYKHLVYEEEHLWLEKLAPSMDNIVVVGSFSKDIAIPGGR
HHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCC
LGYVYGSGNTISEMTKLKGVLGIVAPVPMQWMAYYYLSQGFKEKYLRDVIPAYKRRRDAA
EEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YEAFRRNLPHARIQKPVASMYLFPDMSYYIKKKGLSDVEFTMKLIEEKGVAMLPGSIFGE
HHHHHHCCCHHHHHHHHHHEEECCCHHHHHHHCCCCHHHHHHHHHHHCCCEECCCHHHHC
AGVNHLRITFVTMDEKNLVEGIERLAEFVGER
CCCCEEEEEEEEECHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]