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The map label for this gene is hypE [C]

Identifier: 218883733

GI number: 218883733

Start: 393955

End: 395004

Strand: Reverse

Name: hypE [C]

Synonym: DKAM_0422

Alternate gene names: 218883733

Gene position: 395004-393955 (Counterclockwise)

Preceding gene: 218883734

Following gene: 218883732

Centisome position: 28.93

GC content: 48.1

Gene sequence:

>1050_bases
GTGCTTTCATTAATGGAGGATAAAATAATTACAACCCTCCACGGGGCTGGCGGAATCGAGTCATGGAATATAATAGAGAA
GCTGATACGTGGACGTGTGCCCAGAGACCTCTGGAGCACACCAGGGGGAGCAGGTCTAGACGTACTCGACGACGGCTCAT
ACATTAGGATCGGTGAGTCATATATAGTGTTCGCTAGCGATGCATATACTGTGAAACCACTGTTCTTTCCAGGCGGAAAT
ATAGGTGAGCTCGTCGCTTCAGGAGTATTAAACGACCTGGTAATGATGGGAGCTCGACCAGTAGCATTCATGGATAACAT
AGTTGTTGAAGAGGGCTTCGCCATAAGGGAATTGGAAGACATAGTGGACTCGATGGTTAAGACGCTCGTTGAAAACAATG
TTGCATTGATTGGCGGGGACTTCAAAGTCATGCCAAGGGGAAGCGTTGATGGAGTAGTTATCTCGGGCTTCGCCATAGGG
GTCTCTGGCAAACCACCCGTGGTTGATTCCATAAAGCCTGGCGATAAAATAATAGTTACAAACTATATTGCGGAGCACGG
CTCGACAATATTAGCTGCCCAGCTGGACATGCTTAACGATGCACCCGGGCTTAAAAGCGATGTAAAGCCTCTTGTTAAAA
CTGTTTTACCAGTAATCGAGGAGTACCGTGACTACATAAACGCGGCTAGGGATCCCACTAGAGGAGGGCTCGCCGCGATA
CTGAATGAGTGGTCTCGTTCCAGCGGCCTAACAATAATTATTGACAAGGGGAAGATACCTGTTAGAAAAGAGGTGGCAGA
GTTTCTTGAGATGCTTGGGGTAGACCCTCTTACACTGGCATCGGAGGGTGTTGCAGTGTTAAGCGTTAGAAGCGAGGTAG
CGGATAAAGTAGTTGAGGCCCTCCGTAGAAACGGTGAGAACCCATATATCATAGGGGAAGTCGTCGAGCCTAGATCAAGG
GAGTTGAGGGGTCGGGTAGTTGCTTTAACAGAGGTTGGGGGTTTAACGATTATTCCCCCTCAAGCATATAACTTACCGAG
GATATGTTAG

Upstream 100 bases:

>100_bases
ATGTAGCGTTGAAAACCGGGAAAGAATACATTCAAGAAGAGGATTTATTCGAGGATACTTAAAAATATAGGTTTCAACAT
CCCATATAGCAGTCTTAGAG

Downstream 100 bases:

>100_bases
GAGGAGTACTATGTGTTTAGGCGTCCCAGGCGAGGTCATAGGTATTGAGGATAATAATGAGCTGAAGACTTTAAGGGTGA
GGATTGGTGGTGTGATCCGC

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MLSLMEDKIITTLHGAGGIESWNIIEKLIRGRVPRDLWSTPGGAGLDVLDDGSYIRIGESYIVFASDAYTVKPLFFPGGN
IGELVASGVLNDLVMMGARPVAFMDNIVVEEGFAIRELEDIVDSMVKTLVENNVALIGGDFKVMPRGSVDGVVISGFAIG
VSGKPPVVDSIKPGDKIIVTNYIAEHGSTILAAQLDMLNDAPGLKSDVKPLVKTVLPVIEEYRDYINAARDPTRGGLAAI
LNEWSRSSGLTIIIDKGKIPVRKEVAEFLEMLGVDPLTLASEGVAVLSVRSEVADKVVEALRRNGENPYIIGEVVEPRSR
ELRGRVVALTEVGGLTIIPPQAYNLPRIC

Sequences:

>Translated_349_residues
MLSLMEDKIITTLHGAGGIESWNIIEKLIRGRVPRDLWSTPGGAGLDVLDDGSYIRIGESYIVFASDAYTVKPLFFPGGN
IGELVASGVLNDLVMMGARPVAFMDNIVVEEGFAIRELEDIVDSMVKTLVENNVALIGGDFKVMPRGSVDGVVISGFAIG
VSGKPPVVDSIKPGDKIIVTNYIAEHGSTILAAQLDMLNDAPGLKSDVKPLVKTVLPVIEEYRDYINAARDPTRGGLAAI
LNEWSRSSGLTIIIDKGKIPVRKEVAEFLEMLGVDPLTLASEGVAVLSVRSEVADKVVEALRRNGENPYIIGEVVEPRSR
ELRGRVVALTEVGGLTIIPPQAYNLPRIC
>Mature_349_residues
MLSLMEDKIITTLHGAGGIESWNIIEKLIRGRVPRDLWSTPGGAGLDVLDDGSYIRIGESYIVFASDAYTVKPLFFPGGN
IGELVASGVLNDLVMMGARPVAFMDNIVVEEGFAIRELEDIVDSMVKTLVENNVALIGGDFKVMPRGSVDGVVISGFAIG
VSGKPPVVDSIKPGDKIIVTNYIAEHGSTILAAQLDMLNDAPGLKSDVKPLVKTVLPVIEEYRDYINAARDPTRGGLAAI
LNEWSRSSGLTIIIDKGKIPVRKEVAEFLEMLGVDPLTLASEGVAVLSVRSEVADKVVEALRRNGENPYIIGEVVEPRSR
ELRGRVVALTEVGGLTIIPPQAYNLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=351, Percent_Identity=32.4786324786325, Blast_Score=161, Evalue=6e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 37514; Mature: 37514

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLMEDKIITTLHGAGGIESWNIIEKLIRGRVPRDLWSTPGGAGLDVLDDGSYIRIGES
CCCCHHHHHHHEECCCCCCCHHHHHHHHHHCCCCHHHHCCCCCCCCEEECCCCEEEECCE
YIVFASDAYTVKPLFFPGGNIGELVASGVLNDLVMMGARPVAFMDNIVVEEGFAIRELED
EEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHH
IVDSMVKTLVENNVALIGGDFKVMPRGSVDGVVISGFAIGVSGKPPVVDSIKPGDKIIVT
HHHHHHHHHHHCCEEEEECCEEEEECCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEE
NYIAEHGSTILAAQLDMLNDAPGLKSDVKPLVKTVLPVIEEYRDYINAARDPTRGGLAAI
EEHHHCCCEEEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
LNEWSRSSGLTIIIDKGKIPVRKEVAEFLEMLGVDPLTLASEGVAVLSVRSEVADKVVEA
HHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCHHCCCCCEEEEHHHHHHHHHHHHH
LRRNGENPYIIGEVVEPRSRELRGRVVALTEVGGLTIIPPQAYNLPRIC
HHHCCCCCEEEEEECCCCHHHHCCEEEEEEECCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MLSLMEDKIITTLHGAGGIESWNIIEKLIRGRVPRDLWSTPGGAGLDVLDDGSYIRIGES
CCCCHHHHHHHEECCCCCCCHHHHHHHHHHCCCCHHHHCCCCCCCCEEECCCCEEEECCE
YIVFASDAYTVKPLFFPGGNIGELVASGVLNDLVMMGARPVAFMDNIVVEEGFAIRELED
EEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHH
IVDSMVKTLVENNVALIGGDFKVMPRGSVDGVVISGFAIGVSGKPPVVDSIKPGDKIIVT
HHHHHHHHHHHCCEEEEECCEEEEECCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEE
NYIAEHGSTILAAQLDMLNDAPGLKSDVKPLVKTVLPVIEEYRDYINAARDPTRGGLAAI
EEHHHCCCEEEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
LNEWSRSSGLTIIIDKGKIPVRKEVAEFLEMLGVDPLTLASEGVAVLSVRSEVADKVVEA
HHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCHHCCCCCEEEEHHHHHHHHHHHHH
LRRNGENPYIIGEVVEPRSRELRGRVVALTEVGGLTIIPPQAYNLPRIC
HHHCCCCCEEEEEECCCCHHHHCCEEEEEEECCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]