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The map label for this gene is 218883734

Identifier: 218883734

GI number: 218883734

Start: 395043

End: 396596

Strand: Reverse

Name: 218883734

Synonym: DKAM_0423

Alternate gene names: NA

Gene position: 396596-395043 (Counterclockwise)

Preceding gene: 218883735

Following gene: 218883733

Centisome position: 29.05

GC content: 47.04

Gene sequence:

>1554_bases
TTGAGGATAGCATTGGTGACTGGTAGGCTAGCAGGGGATGCTATTAGGAAAATAGCGTCGGGGATCAATGTTTCCGGGAT
CGAGTTAGTAGTCGTGGAATTACCAATACCTGTAGCAGCCATGATGAGTGATACTTATCTCGAGAAGGAGCTGCCTAGGC
ACATGGATGTGCTTGGAAACGTGGACCTGGTTATAGTTCCGGGATACACTAGTGGTGACCTCACGAGGGTATCAGAACTT
ATCGGTAAACCGGTGGTAAAGGGGGTGAAGTACATGTATGACATCCCATTAATGATTAAAGCCATCTCCAATGGTATTGA
ACTCTCACCCAGGACGCCGGCAGATGATGTGGTAAGGCTCTATAGGGCTGAGAGAGATAAAGAGGTGCTCAGGGGTCTCA
GAGAAAAGGCTAGTACACAATACTATTTCACCATAGGGGATAGATATAAAATCTACGTGAGCCCCGTTTATCCTATTATC
ATCCACGAGGTATACATGGGACATGATGCATACACGCTTGACGACATCATCAAGAAATCCGAGAAGGCTTTACTCGATGG
AGCTGATATAGTTGTAGTCGGGTTTCCCCATAACGCACCGGTAGATATCATTGAAGAGGTGGTTGCAGAAGTAAAGAAGA
GGCTTGGAAGACCCATTGGCGTTGATGTAGAGGATGTCAACGCACTATTGAAAGCTGCTGAGGCCGGAGCAGATGTGTTG
ATGAGTCTCAGTTACTCTAAGATAATGATGCTTGATAATGCATCATCCATTAGCGATAAAGCCGTTGTCTTGATACCGGA
TCACAGCATCCACGAGGAAGACAAGCTTGGTAGTCTTGTAGAGGCATATAAGCTGGCAGTGGAGAAAGGGCTCTCAAAGA
TAATAGTGGATCCTGTCCTAGACCCCCCGCTTAGCGGGCTTGCATCCTCCCTAGAGAGATACAGGGCGGCAAGACGGTTG
TTCCCTCATACTCCATTATTAATGGGTGTTGGAAACGTTACCGAGCTAATAGACGCTGACAGCGTTGGCGTAAACGCTAT
CCTGGCATCGATAGGTGTTGAAATCGGGGTCGAAGCTTATTTGACAACTGAGGCTAGTGTGAAGACGCGTGGCTCCACCA
GGGAGCTTAGAAGAGCCCTCGACATGTGCCTTATAGCGCGTAACGAGTCCAGGCCTCCAAAGGATTTATCCATAAACCTT
CTGTTACTGAAGGATAAGCGGAGGAAGTCTATTGGTACCAGGCAGCGTGGTGTAATCCTGTATGCTAGGGAAAGAAGGAG
CTCGGGGATCGATCCAAAAGGCGTTTTTAAGATATATGTGGATCATGATGCTGGAAACATCATCGTCGAGCACTACAGGC
TCGGAGAATTAGAGCCCGACTACACTATCATTGGGAATGATCCATACGCTATACTTTCAGAGATAACTGGGGGACAGCTC
GCTTCAAAGCCCGAGCACTATTTCTACTTGGGCTACGAGTTAAGCAAGGCATATGTAGCGTTGAAAACCGGGAAAGAATA
CATTCAAGAAGAGGATTTATTCGAGGATACTTAA

Upstream 100 bases:

>100_bases
TCCATTCTACGTGGGTATCATTAAGAGGCTTAACGATATAGAGGGCGTGGAGATAATAGATCACCCTGACAGGATCTTAG
AATACATCTAGGTGAATTAA

Downstream 100 bases:

>100_bases
AAATATAGGTTTCAACATCCCATATAGCAGTCTTAGAGGTGCTTTCATTAATGGAGGATAAAATAATTACAACCCTCCAC
GGGGCTGGCGGAATCGAGTC

Product: dihydropteroate synthase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MRIALVTGRLAGDAIRKIASGINVSGIELVVVELPIPVAAMMSDTYLEKELPRHMDVLGNVDLVIVPGYTSGDLTRVSEL
IGKPVVKGVKYMYDIPLMIKAISNGIELSPRTPADDVVRLYRAERDKEVLRGLREKASTQYYFTIGDRYKIYVSPVYPII
IHEVYMGHDAYTLDDIIKKSEKALLDGADIVVVGFPHNAPVDIIEEVVAEVKKRLGRPIGVDVEDVNALLKAAEAGADVL
MSLSYSKIMMLDNASSISDKAVVLIPDHSIHEEDKLGSLVEAYKLAVEKGLSKIIVDPVLDPPLSGLASSLERYRAARRL
FPHTPLLMGVGNVTELIDADSVGVNAILASIGVEIGVEAYLTTEASVKTRGSTRELRRALDMCLIARNESRPPKDLSINL
LLLKDKRRKSIGTRQRGVILYARERRSSGIDPKGVFKIYVDHDAGNIIVEHYRLGELEPDYTIIGNDPYAILSEITGGQL
ASKPEHYFYLGYELSKAYVALKTGKEYIQEEDLFEDT

Sequences:

>Translated_517_residues
MRIALVTGRLAGDAIRKIASGINVSGIELVVVELPIPVAAMMSDTYLEKELPRHMDVLGNVDLVIVPGYTSGDLTRVSEL
IGKPVVKGVKYMYDIPLMIKAISNGIELSPRTPADDVVRLYRAERDKEVLRGLREKASTQYYFTIGDRYKIYVSPVYPII
IHEVYMGHDAYTLDDIIKKSEKALLDGADIVVVGFPHNAPVDIIEEVVAEVKKRLGRPIGVDVEDVNALLKAAEAGADVL
MSLSYSKIMMLDNASSISDKAVVLIPDHSIHEEDKLGSLVEAYKLAVEKGLSKIIVDPVLDPPLSGLASSLERYRAARRL
FPHTPLLMGVGNVTELIDADSVGVNAILASIGVEIGVEAYLTTEASVKTRGSTRELRRALDMCLIARNESRPPKDLSINL
LLLKDKRRKSIGTRQRGVILYARERRSSGIDPKGVFKIYVDHDAGNIIVEHYRLGELEPDYTIIGNDPYAILSEITGGQL
ASKPEHYFYLGYELSKAYVALKTGKEYIQEEDLFEDT
>Mature_517_residues
MRIALVTGRLAGDAIRKIASGINVSGIELVVVELPIPVAAMMSDTYLEKELPRHMDVLGNVDLVIVPGYTSGDLTRVSEL
IGKPVVKGVKYMYDIPLMIKAISNGIELSPRTPADDVVRLYRAERDKEVLRGLREKASTQYYFTIGDRYKIYVSPVYPII
IHEVYMGHDAYTLDDIIKKSEKALLDGADIVVVGFPHNAPVDIIEEVVAEVKKRLGRPIGVDVEDVNALLKAAEAGADVL
MSLSYSKIMMLDNASSISDKAVVLIPDHSIHEEDKLGSLVEAYKLAVEKGLSKIIVDPVLDPPLSGLASSLERYRAARRL
FPHTPLLMGVGNVTELIDADSVGVNAILASIGVEIGVEAYLTTEASVKTRGSTRELRRALDMCLIARNESRPPKDLSINL
LLLKDKRRKSIGTRQRGVILYARERRSSGIDPKGVFKIYVDHDAGNIIVEHYRLGELEPDYTIIGNDPYAILSEITGGQL
ASKPEHYFYLGYELSKAYVALKTGKEYIQEEDLFEDT

Specific function: Unknown. Does not possess dihydropteroate synthase (DHPS) activity since it does not catalyze the condensation of 6- hydroxymethyl-7,8-dihydropterin pyrophosphate (DHPP) and 4- aminobenzoate to form 7,8-dihydropteroate [H]

COG id: COG0294

COG function: function code H; Dihydropteroate synthase and related enzymes

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005236
- InterPro:   IPR011005
- InterPro:   IPR000489 [H]

Pfam domain/function: PF00809 Pterin_bind [H]

EC number: NA

Molecular weight: Translated: 57060; Mature: 57060

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS50972 PTERIN_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIALVTGRLAGDAIRKIASGINVSGIELVVVELPIPVAAMMSDTYLEKELPRHMDVLGN
CEEEEEECCHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
VDLVIVPGYTSGDLTRVSELIGKPVVKGVKYMYDIPLMIKAISNGIELSPRTPADDVVRL
CCEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHH
YRAERDKEVLRGLREKASTQYYFTIGDRYKIYVSPVYPIIIHEVYMGHDAYTLDDIIKKS
HHHHHHHHHHHHHHHHHCCEEEEEECCEEEEEECCCCHHHHHHHHHCCCCEEHHHHHHHH
EKALLDGADIVVVGFPHNAPVDIIEEVVAEVKKRLGRPIGVDVEDVNALLKAAEAGADVL
HHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHH
MSLSYSKIMMLDNASSISDKAVVLIPDHSIHEEDKLGSLVEAYKLAVEKGLSKIIVDPVL
HHCCCCEEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCHHHEECCCCC
DPPLSGLASSLERYRAARRLFPHTPLLMGVGNVTELIDADSVGVNAILASIGVEIGVEAY
CCCHHHHHHHHHHHHHHHHHCCCCCHHEECCCHHHHHCCCCCCHHHHHHHHCHHCCCEEE
LTTEASVKTRGSTRELRRALDMCLIARNESRPPKDLSINLLLLKDKRRKSIGTRQRGVIL
EECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHCCCCCCCEEE
YARERRSSGIDPKGVFKIYVDHDAGNIIVEHYRLGELEPDYTIIGNDPYAILSEITGGQL
EEECCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCEEEECCCHHHHHHHCCCCCC
ASKPEHYFYLGYELSKAYVALKTGKEYIQEEDLFEDT
CCCCCCEEEEEEEECCEEEEECCCHHHHHHHHCCCCC
>Mature Secondary Structure
MRIALVTGRLAGDAIRKIASGINVSGIELVVVELPIPVAAMMSDTYLEKELPRHMDVLGN
CEEEEEECCHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
VDLVIVPGYTSGDLTRVSELIGKPVVKGVKYMYDIPLMIKAISNGIELSPRTPADDVVRL
CCEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHH
YRAERDKEVLRGLREKASTQYYFTIGDRYKIYVSPVYPIIIHEVYMGHDAYTLDDIIKKS
HHHHHHHHHHHHHHHHHCCEEEEEECCEEEEEECCCCHHHHHHHHHCCCCEEHHHHHHHH
EKALLDGADIVVVGFPHNAPVDIIEEVVAEVKKRLGRPIGVDVEDVNALLKAAEAGADVL
HHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHH
MSLSYSKIMMLDNASSISDKAVVLIPDHSIHEEDKLGSLVEAYKLAVEKGLSKIIVDPVL
HHCCCCEEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCHHHEECCCCC
DPPLSGLASSLERYRAARRLFPHTPLLMGVGNVTELIDADSVGVNAILASIGVEIGVEAY
CCCHHHHHHHHHHHHHHHHHCCCCCHHEECCCHHHHHCCCCCCHHHHHHHHCHHCCCEEE
LTTEASVKTRGSTRELRRALDMCLIARNESRPPKDLSINLLLLKDKRRKSIGTRQRGVIL
EECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHCCCCCCCEEE
YARERRSSGIDPKGVFKIYVDHDAGNIIVEHYRLGELEPDYTIIGNDPYAILSEITGGQL
EEECCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCEEEECCCHHHHHHHCCCCCC
ASKPEHYFYLGYELSKAYVALKTGKEYIQEEDLFEDT
CCCCCCEEEEEEEECCEEEEECCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]