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The map label for this gene is dppB [H]

Identifier: 218883543

GI number: 218883543

Start: 215324

End: 216346

Strand: Direct

Name: dppB [H]

Synonym: DKAM_0232

Alternate gene names: 218883543

Gene position: 215324-216346 (Clockwise)

Preceding gene: 218883542

Following gene: 218883544

Centisome position: 15.77

GC content: 45.94

Gene sequence:

>1023_bases
GTGAGCATAAACTATGTTGTGAAAAGGGTTTTTTGGTGTATCCTAATAGTTTTCGGGATAATTGTTTTTTCATACTTGAT
CCTCATTTTCTCACCGGGAGATCCGGCTGTTAAATGGGCTGGAAACCCAAGGGGACCGTATGCCTCAATGGCTATTGAGA
AAGCTAGGGAGGAACTCGGACTCAATGATCCATTATACCTGCAGATCGCTAGATTCGTGTATAACGTTTTCAACGGTAAT
ATAGGGGATAGCATCGCCTATAAGCAGCCAGTGCTACCACTCATCTACTCAAGGCTTCAATCGACACTGGAGCTACTTGT
AATCGCGTATGTTATAGCTGTACCGCTGGGAATTTTCCTAGGTATTTACTCGGCGTTGAGAAGGGGTAGTAGGAGCGACT
CCTTGATACAGGCTGTCGGCACGATCTTAGCGAACATGCCTACTTTCTGGGTTGCAACGGGGCTCTTCCTAGTGTTTTCG
ATGTCAGGGATCTCATTATACGGTAGGATTAATACAAGGTTGGCTTTATCAACGGGGTTTCACCCTATAACTGGGTTCTA
CTTACTTGACAGCCTTATCCAGGGCAACCTACTCGTCTTCATCGATGTCCTACTACGACTACTGCCTCCAGCTCTCGCCG
TAGCTGTATACCCGCTTGGAGTATTAATCAGGTTAACGAGAACCCTCATGGCTGAGGCGCTCCTAGAGGACTTCGTAAGA
GTGCCTGTTGCATGGGGGGTTAGGAGGGATATAATCATATGGAGATATGCATTAAAGGCATCTATCCCAGGCGTGATACA
GATAAGTGGGCTTTCATTCGCATACAGCCTTATTGATGCTATGGTTGTGGAATACACGGTGTTCGGTAGGGAGGGGCTTG
GAAATCTATTATACGATGCACTCAACTACTCTGATTTCAGGCTAGCAATAGGCTTAATCACTGTAGTAGCTGTCTTCTAC
CTCGTGGTTAACACACTAACTGATATAATTCAGGCACTCGTAGATCCAAGGGTGAGGCTATGA

Upstream 100 bases:

>100_bases
ATCTATAGTGGGAAACTGGAGATACCGGAGGAAGCCATGAACCCGCTTTACATGTATGTCGTGTTTTTCCAGTACGTGAA
GGTGAAAGCGTAAATTGCCC

Downstream 100 bases:

>100_bases
ACAGTATTGAGGCAAATATTAGGGGTGCAGCATACCTTGTCAGGAAACAGTTTAGGAAGACGAGGTTTAAAACAGGTTTA
GCAATAGTGTTGGTGATCAC

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSINYVVKRVFWCILIVFGIIVFSYLILIFSPGDPAVKWAGNPRGPYASMAIEKAREELGLNDPLYLQIARFVYNVFNGN
IGDSIAYKQPVLPLIYSRLQSTLELLVIAYVIAVPLGIFLGIYSALRRGSRSDSLIQAVGTILANMPTFWVATGLFLVFS
MSGISLYGRINTRLALSTGFHPITGFYLLDSLIQGNLLVFIDVLLRLLPPALAVAVYPLGVLIRLTRTLMAEALLEDFVR
VPVAWGVRRDIIIWRYALKASIPGVIQISGLSFAYSLIDAMVVEYTVFGREGLGNLLYDALNYSDFRLAIGLITVVAVFY
LVVNTLTDIIQALVDPRVRL

Sequences:

>Translated_340_residues
MSINYVVKRVFWCILIVFGIIVFSYLILIFSPGDPAVKWAGNPRGPYASMAIEKAREELGLNDPLYLQIARFVYNVFNGN
IGDSIAYKQPVLPLIYSRLQSTLELLVIAYVIAVPLGIFLGIYSALRRGSRSDSLIQAVGTILANMPTFWVATGLFLVFS
MSGISLYGRINTRLALSTGFHPITGFYLLDSLIQGNLLVFIDVLLRLLPPALAVAVYPLGVLIRLTRTLMAEALLEDFVR
VPVAWGVRRDIIIWRYALKASIPGVIQISGLSFAYSLIDAMVVEYTVFGREGLGNLLYDALNYSDFRLAIGLITVVAVFY
LVVNTLTDIIQALVDPRVRL
>Mature_339_residues
SINYVVKRVFWCILIVFGIIVFSYLILIFSPGDPAVKWAGNPRGPYASMAIEKAREELGLNDPLYLQIARFVYNVFNGNI
GDSIAYKQPVLPLIYSRLQSTLELLVIAYVIAVPLGIFLGIYSALRRGSRSDSLIQAVGTILANMPTFWVATGLFLVFSM
SGISLYGRINTRLALSTGFHPITGFYLLDSLIQGNLLVFIDVLLRLLPPALAVAVYPLGVLIRLTRTLMAEALLEDFVRV
PVAWGVRRDIIIWRYALKASIPGVIQISGLSFAYSLIDAMVVEYTVFGREGLGNLLYDALNYSDFRLAIGLITVVAVFYL
VVNTLTDIIQALVDPRVRL

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=344, Percent_Identity=32.8488372093023, Blast_Score=165, Evalue=5e-42,
Organism=Escherichia coli, GI1787761, Length=334, Percent_Identity=35.3293413173653, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI1787053, Length=338, Percent_Identity=28.698224852071, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787497, Length=338, Percent_Identity=25.7396449704142, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787550, Length=269, Percent_Identity=27.8810408921933, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789888, Length=338, Percent_Identity=24.8520710059172, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1788504, Length=291, Percent_Identity=23.7113402061856, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37707; Mature: 37576

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSINYVVKRVFWCILIVFGIIVFSYLILIFSPGDPAVKWAGNPRGPYASMAIEKAREELG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHCC
LNDPLYLQIARFVYNVFNGNIGDSIAYKQPVLPLIYSRLQSTLELLVIAYVIAVPLGIFL
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIYSALRRGSRSDSLIQAVGTILANMPTFWVATGLFLVFSMSGISLYGRINTRLALSTGF
HHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCC
HPITGFYLLDSLIQGNLLVFIDVLLRLLPPALAVAVYPLGVLIRLTRTLMAEALLEDFVR
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPVAWGVRRDIIIWRYALKASIPGVIQISGLSFAYSLIDAMVVEYTVFGREGLGNLLYDA
HHHHHCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
LNYSDFRLAIGLITVVAVFYLVVNTLTDIIQALVDPRVRL
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SINYVVKRVFWCILIVFGIIVFSYLILIFSPGDPAVKWAGNPRGPYASMAIEKAREELG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHCC
LNDPLYLQIARFVYNVFNGNIGDSIAYKQPVLPLIYSRLQSTLELLVIAYVIAVPLGIFL
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIYSALRRGSRSDSLIQAVGTILANMPTFWVATGLFLVFSMSGISLYGRINTRLALSTGF
HHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCC
HPITGFYLLDSLIQGNLLVFIDVLLRLLPPALAVAVYPLGVLIRLTRTLMAEALLEDFVR
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPVAWGVRRDIIIWRYALKASIPGVIQISGLSFAYSLIDAMVVEYTVFGREGLGNLLYDA
HHHHHCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
LNYSDFRLAIGLITVVAVFYLVVNTLTDIIQALVDPRVRL
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]