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The map label for this gene is soxA [H]

Identifier: 218883518

GI number: 218883518

Start: 194578

End: 196047

Strand: Direct

Name: soxA [H]

Synonym: DKAM_0207

Alternate gene names: 218883518

Gene position: 194578-196047 (Clockwise)

Preceding gene: 218883516

Following gene: 218883519

Centisome position: 14.25

GC content: 47.41

Gene sequence:

>1470_bases
GTGCTAGATTACAGGATATATGAACACCCCATAATAGATTTCAAGCGGGGACGGCTCATCAAGTTCACTTATAATGGCAA
CATTATAGAGGCATATGAGGGAGAAAGCATACTTGCCTCTCTATATGCTTTAGGCTACAGGGTTTTCTCCAGGAGCCCCG
ATGGTAGCAGGCCCCGGGGCGCTTTCTGCATGATTGGCAAGTGCTCTAGCTGCCTCTCATATGTTAACAATGTTCCAAAT
ACAAGGATATGTATTGAGCCAGTGAGAGATGGAATTAATGTGGTAAGTGGAGACGGTATCCCGGAGCCGCCAGCTAATAT
TAGTAGTGCATCCGTGAGAAAGGAGATAGTGGATACGGATGTCCTTGTAATTGGTGCTGGTCCAGCTGGGCTCCAAGCAG
CTTTAAAGCTGGGTGAGAAAGGCGTTGATGTGGTCCTCGTTACAGATCACTTCAGGCTTGGAGGCCAGCTGGTTAAGCAG
ACCCATAAGTTCTTCGGTGATACAAGATACTATGGTGGTGTAAGAGGCTTCAAAATAGCTGAGAAACTGGTCAACGAGCT
CAAGAAGTATTCGACCATTAAAACATATACAAGAGCTTTTGCCTACGGGTTCTTCGGTGAGGGTTATATGGGTATAGCCG
TCCAGGGGGAGGAACCTGTTAACCTACTTGTCAAACCCAGGTACACTATAATCGCAACAGGTGCAACTGAGAGGATGATT
TTATTCGAGAACAATGACCTACCAGGTGTCATGGGGGCTGGCGGTGCTCAGACACTTATGAATGAATATGGTGTTAGACC
AGGTGAGAATGCGTTGGTTGTGGGTAGCGGTAATGTCGGATTAATAGTGGCTTATCAATTACTGCAAGCCGGGGTAAGGG
TTCACGGTATAATTGAGATAATGAGAGAGATCGGTGGCTGGATCGTCCACGCAGCAAAGGTGAGGAGGTATGGAGTGCCA
ATCCTCACTGGTCATACAATTACAAGGGTTGAGGGGGCAGAGAAAGTTGAGAAAGCAATAGTAGCGGCTGTCGACGATAA
GTTGAACCCTATCCAGGGCTCGGAGAAGGAATATAGCGTAGACCTAGTCCTCCTAGCGGTTGGTTTACAACCTAATTATG
CACTCCTGAGTCAAATGGGGGCTACTATGAAGTATATTCCAGAAGCCGGCGGCCTTGTACCAGTTAGAACGAAATACATG
GAGACAAGTATACCAGGTGTTTTCGTGGCAGGCGATCTAACGGGTATTGAGGAAGCCACAACAGCCTTCATAGAGGGAGA
GATTGCGGCATATACGATCCTTGAGAGAATGGGGTTTACGGATGTGATCACTGAAAGAGATAGATTGGTGGATTTCCTGT
GGAACGAATACAGGATGAGCCCTGTTATCTCAAGGGCTAGGCAGGGCAAGCTCAAAGCCACTGTAACAGAGGAGGAGATG
GAGAAGCTTAGGAGGGGGATGGATATATGA

Upstream 100 bases:

>100_bases
TAATCCCAGGGGCATTAAATATTTATTTCCGGTAGTATCCTAGTGTATATATATTGTATATATATTATTTAAGGAGCTGC
TTAATACGTGGTGGGAGCTG

Downstream 100 bases:

>100_bases
GCTCTAAGCGGACAGGCATTATAACTAAAGAGGAACTAGTAGAGAAGAAGCTGCTTCCATCCATGGAGAGGCTCTCCAAT
GGACCCATAGCCATACTTGA

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: Sarcosine oxidase subunit [H]

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MLDYRIYEHPIIDFKRGRLIKFTYNGNIIEAYEGESILASLYALGYRVFSRSPDGSRPRGAFCMIGKCSSCLSYVNNVPN
TRICIEPVRDGINVVSGDGIPEPPANISSASVRKEIVDTDVLVIGAGPAGLQAALKLGEKGVDVVLVTDHFRLGGQLVKQ
THKFFGDTRYYGGVRGFKIAEKLVNELKKYSTIKTYTRAFAYGFFGEGYMGIAVQGEEPVNLLVKPRYTIIATGATERMI
LFENNDLPGVMGAGGAQTLMNEYGVRPGENALVVGSGNVGLIVAYQLLQAGVRVHGIIEIMREIGGWIVHAAKVRRYGVP
ILTGHTITRVEGAEKVEKAIVAAVDDKLNPIQGSEKEYSVDLVLLAVGLQPNYALLSQMGATMKYIPEAGGLVPVRTKYM
ETSIPGVFVAGDLTGIEEATTAFIEGEIAAYTILERMGFTDVITERDRLVDFLWNEYRMSPVISRARQGKLKATVTEEEM
EKLRRGMDI

Sequences:

>Translated_489_residues
MLDYRIYEHPIIDFKRGRLIKFTYNGNIIEAYEGESILASLYALGYRVFSRSPDGSRPRGAFCMIGKCSSCLSYVNNVPN
TRICIEPVRDGINVVSGDGIPEPPANISSASVRKEIVDTDVLVIGAGPAGLQAALKLGEKGVDVVLVTDHFRLGGQLVKQ
THKFFGDTRYYGGVRGFKIAEKLVNELKKYSTIKTYTRAFAYGFFGEGYMGIAVQGEEPVNLLVKPRYTIIATGATERMI
LFENNDLPGVMGAGGAQTLMNEYGVRPGENALVVGSGNVGLIVAYQLLQAGVRVHGIIEIMREIGGWIVHAAKVRRYGVP
ILTGHTITRVEGAEKVEKAIVAAVDDKLNPIQGSEKEYSVDLVLLAVGLQPNYALLSQMGATMKYIPEAGGLVPVRTKYM
ETSIPGVFVAGDLTGIEEATTAFIEGEIAAYTILERMGFTDVITERDRLVDFLWNEYRMSPVISRARQGKLKATVTEEEM
EKLRRGMDI
>Mature_489_residues
MLDYRIYEHPIIDFKRGRLIKFTYNGNIIEAYEGESILASLYALGYRVFSRSPDGSRPRGAFCMIGKCSSCLSYVNNVPN
TRICIEPVRDGINVVSGDGIPEPPANISSASVRKEIVDTDVLVIGAGPAGLQAALKLGEKGVDVVLVTDHFRLGGQLVKQ
THKFFGDTRYYGGVRGFKIAEKLVNELKKYSTIKTYTRAFAYGFFGEGYMGIAVQGEEPVNLLVKPRYTIIATGATERMI
LFENNDLPGVMGAGGAQTLMNEYGVRPGENALVVGSGNVGLIVAYQLLQAGVRVHGIIEIMREIGGWIVHAAKVRRYGVP
ILTGHTITRVEGAEKVEKAIVAAVDDKLNPIQGSEKEYSVDLVLLAVGLQPNYALLSQMGATMKYIPEAGGLVPVRTKYM
ETSIPGVFVAGDLTGIEEATTAFIEGEIAAYTILERMGFTDVITERDRLVDFLWNEYRMSPVISRARQGKLKATVTEEEM
EKLRRGMDI

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

None

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006277 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C; PF07992 Pyr_redox_2 [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 53555; Mature: 53555

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS00197 2FE2S_FER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDYRIYEHPIIDFKRGRLIKFTYNGNIIEAYEGESILASLYALGYRVFSRSPDGSRPRG
CCCCEEECCCCEEECCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCC
AFCMIGKCSSCLSYVNNVPNTRICIEPVRDGINVVSGDGIPEPPANISSASVRKEIVDTD
CEEEECCHHHHHHHHHCCCCCEEEEEEHHCCCEEEECCCCCCCCCCCCHHHHHHHHCCCC
VLVIGAGPAGLQAALKLGEKGVDVVLVTDHFRLGGQLVKQTHKFFGDTRYYGGVRGFKIA
EEEEECCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCHHCCCCCHHHHH
EKLVNELKKYSTIKTYTRAFAYGFFGEGYMGIAVQGEEPVNLLVKPRYTIIATGATERMI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCEEEEEECCCCEEE
LFENNDLPGVMGAGGAQTLMNEYGVRPGENALVVGSGNVGLIVAYQLLQAGVRVHGIIEI
EEECCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHH
MREIGGWIVHAAKVRRYGVPILTGHTITRVEGAEKVEKAIVAAVDDKLNPIQGSEKEYSV
HHHHHHHEEEHHHHHHCCCCEEECCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCEEE
DLVLLAVGLQPNYALLSQMGATMKYIPEAGGLVPVRTKYMETSIPGVFVAGDLTGIEEAT
EEEEEEECCCCCHHHHHHCCCHHEECCCCCCEEEEEHHHHHCCCCCEEEECCCCCCHHHH
TAFIEGEIAAYTILERMGFTDVITERDRLVDFLWNEYRMSPVISRARQGKLKATVTEEEM
HHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEECHHHH
EKLRRGMDI
HHHHHCCCC
>Mature Secondary Structure
MLDYRIYEHPIIDFKRGRLIKFTYNGNIIEAYEGESILASLYALGYRVFSRSPDGSRPRG
CCCCEEECCCCEEECCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCC
AFCMIGKCSSCLSYVNNVPNTRICIEPVRDGINVVSGDGIPEPPANISSASVRKEIVDTD
CEEEECCHHHHHHHHHCCCCCEEEEEEHHCCCEEEECCCCCCCCCCCCHHHHHHHHCCCC
VLVIGAGPAGLQAALKLGEKGVDVVLVTDHFRLGGQLVKQTHKFFGDTRYYGGVRGFKIA
EEEEECCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCHHCCCCCHHHHH
EKLVNELKKYSTIKTYTRAFAYGFFGEGYMGIAVQGEEPVNLLVKPRYTIIATGATERMI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCEEEEEECCCCEEE
LFENNDLPGVMGAGGAQTLMNEYGVRPGENALVVGSGNVGLIVAYQLLQAGVRVHGIIEI
EEECCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHH
MREIGGWIVHAAKVRRYGVPILTGHTITRVEGAEKVEKAIVAAVDDKLNPIQGSEKEYSV
HHHHHHHEEEHHHHHHCCCCEEECCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCEEE
DLVLLAVGLQPNYALLSQMGATMKYIPEAGGLVPVRTKYMETSIPGVFVAGDLTGIEEAT
EEEEEEECCCCCHHHHHHCCCHHEECCCCCCEEEEEHHHHHCCCCCEEEECCCCCCHHHH
TAFIEGEIAAYTILERMGFTDVITERDRLVDFLWNEYRMSPVISRARQGKLKATVTEEEM
HHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEECHHHH
EKLRRGMDI
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]