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The map label for this gene is ywlC [H]

Identifier: 218883353

GI number: 218883353

Start: 33741

End: 34820

Strand: Reverse

Name: ywlC [H]

Synonym: DKAM_0039

Alternate gene names: 218883353

Gene position: 34820-33741 (Counterclockwise)

Preceding gene: 218883355

Following gene: 218883350

Centisome position: 2.55

GC content: 44.26

Gene sequence:

>1080_bases
GTGGGGGTTGTGACACTTATTTTAAGAACTGATCCACTTAATCCCAGTAGGGAGCTCCTGATCCAAGCCGCAAGAATATT
GTTGAATAAGGGTATAGTAGCCTTTCCAACCGAGACAGTGTATGGGCTCGGCGCAGTCATATATTACGAGGATGCTGTTG
AGAAGATATTTAAGGCCAAGATGAGACCTCCCGACAACCCCTTAATCATACATATATCTACTCTAGACATGCTTGAAGAA
GTCGCATTGAATATACCTGAAGACGCATATAGTTTGATAAATAGATTCTGGCCAGGCCCCTTAACGCTGATATTACCGAG
AAACCCAAGGGTACCCAAGATAGTTACAGGAGGATTAGACACTATAGCTGTAAGAATGCCGGGTCATCCAACAGCTCTTG
AGTTAATCAACGTGGTTGGCTACCCGATAGCCGCTCCAAGCGCTAATCTCTCCGGTAGACCAAGCCCTGTAACGGCTGAA
CACGTGATAAGGGATCTCATGGGCAGAATTGATGCGATTATAGATGCAGGAGAGACGTTTTTCGGGGTGGAATCAACGGT
TGTGAATATACTTGAGGACCCGCCCACCTTACTCAGGCCTGGTGCCTACCCAGTGGAGGAGATCGAGAAGGTACTTGGAA
GAAAAATAGCTATACCTGATTTCGCCAGGGGCCTCAAATACTCGGAGGTGGCTCTAGCACCCGGAATGAAGTATAGGCAT
TACTCTCCGGAGGCAAAGTTAATCCTAGTTGAGTCTGTGACAAATGATTACAGCGTAATTGCTAATAAAATCATCGAGGC
GGCTAGAGATATTAGTGTATCCACTAATAGCGATATATGCATAGTTTCATCTATTGAAACAAGTAGTTATTACAGGAAGC
TGGAGAAAGTGAAAGCCGTATTAATCATTGGCTCTAGGAGAAACCTGTATGAAGTAGCCAAAAACCTCTTCAAAATACTG
AGAGACGTTGATAATATAGGGTGTAAAACAGTATTTGTGGAGGGATTCCCTGAAACAGGTATCGGGTTAGCAGTTATGAA
CAGGCTTAGAAAGGCGTCTTCAAGCATTATACGTGTCTAA

Upstream 100 bases:

>100_bases
TTCTCCCCATGTTCAAGAAGACATCAACCCTTACATATCGTAATAATTCATAAGTTTAAACAGGATTATAATCATTGTTA
AATAGTTAGGCAGGAAATCG

Downstream 100 bases:

>100_bases
TACATTCTTGACTTCGACTTCTCTAACCACATATCCCGGTAGGTAGATACTCATTATCTCTTTAACAATACTCCTTATCT
TCGAGTTTATGAGGGGATCC

Product: Putative translation factor

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MGVVTLILRTDPLNPSRELLIQAARILLNKGIVAFPTETVYGLGAVIYYEDAVEKIFKAKMRPPDNPLIIHISTLDMLEE
VALNIPEDAYSLINRFWPGPLTLILPRNPRVPKIVTGGLDTIAVRMPGHPTALELINVVGYPIAAPSANLSGRPSPVTAE
HVIRDLMGRIDAIIDAGETFFGVESTVVNILEDPPTLLRPGAYPVEEIEKVLGRKIAIPDFARGLKYSEVALAPGMKYRH
YSPEAKLILVESVTNDYSVIANKIIEAARDISVSTNSDICIVSSIETSSYYRKLEKVKAVLIIGSRRNLYEVAKNLFKIL
RDVDNIGCKTVFVEGFPETGIGLAVMNRLRKASSSIIRV

Sequences:

>Translated_359_residues
MGVVTLILRTDPLNPSRELLIQAARILLNKGIVAFPTETVYGLGAVIYYEDAVEKIFKAKMRPPDNPLIIHISTLDMLEE
VALNIPEDAYSLINRFWPGPLTLILPRNPRVPKIVTGGLDTIAVRMPGHPTALELINVVGYPIAAPSANLSGRPSPVTAE
HVIRDLMGRIDAIIDAGETFFGVESTVVNILEDPPTLLRPGAYPVEEIEKVLGRKIAIPDFARGLKYSEVALAPGMKYRH
YSPEAKLILVESVTNDYSVIANKIIEAARDISVSTNSDICIVSSIETSSYYRKLEKVKAVLIIGSRRNLYEVAKNLFKIL
RDVDNIGCKTVFVEGFPETGIGLAVMNRLRKASSSIIRV
>Mature_358_residues
GVVTLILRTDPLNPSRELLIQAARILLNKGIVAFPTETVYGLGAVIYYEDAVEKIFKAKMRPPDNPLIIHISTLDMLEEV
ALNIPEDAYSLINRFWPGPLTLILPRNPRVPKIVTGGLDTIAVRMPGHPTALELINVVGYPIAAPSANLSGRPSPVTAEH
VIRDLMGRIDAIIDAGETFFGVESTVVNILEDPPTLLRPGAYPVEEIEKVLGRKIAIPDFARGLKYSEVALAPGMKYRHY
SPEAKLILVESVTNDYSVIANKIIEAARDISVSTNSDICIVSSIETSSYYRKLEKVKAVLIIGSRRNLYEVAKNLFKILR
DVDNIGCKTVFVEGFPETGIGLAVMNRLRKASSSIIRV

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=151, Percent_Identity=32.4503311258278, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081864, Length=193, Percent_Identity=28.4974093264249, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17537239, Length=210, Percent_Identity=32.8571428571429, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6321269, Length=380, Percent_Identity=39.7368421052632, Blast_Score=225, Evalue=1e-59,
Organism=Drosophila melanogaster, GI78707274, Length=203, Percent_Identity=29.064039408867, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 39453; Mature: 39321

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVVTLILRTDPLNPSRELLIQAARILLNKGIVAFPTETVYGLGAVIYYEDAVEKIFKAK
CCEEEEEEECCCCCHHHHHHHHHHHHHHHCCEEECCCHHHHHCEEEEEEHHHHHHHHHHH
MRPPDNPLIIHISTLDMLEEVALNIPEDAYSLINRFWPGPLTLILPRNPRVPKIVTGGLD
CCCCCCCEEEEEEHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCCC
TIAVRMPGHPTALELINVVGYPIAAPSANLSGRPSPVTAEHVIRDLMGRIDAIIDAGETF
EEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHH
FGVESTVVNILEDPPTLLRPGAYPVEEIEKVLGRKIAIPDFARGLKYSEVALAPGMKYRH
CCHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHCCCCCCCHHHHCCCCCCEEECCCCCEEE
YSPEAKLILVESVTNDYSVIANKIIEAARDISVSTNSDICIVSSIETSSYYRKLEKVKAV
CCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHEEE
LIIGSRRNLYEVAKNLFKILRDVDNIGCKTVFVEGFPETGIGLAVMNRLRKASSSIIRV
EEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GVVTLILRTDPLNPSRELLIQAARILLNKGIVAFPTETVYGLGAVIYYEDAVEKIFKAK
CEEEEEEECCCCCHHHHHHHHHHHHHHHCCEEECCCHHHHHCEEEEEEHHHHHHHHHHH
MRPPDNPLIIHISTLDMLEEVALNIPEDAYSLINRFWPGPLTLILPRNPRVPKIVTGGLD
CCCCCCCEEEEEEHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCCC
TIAVRMPGHPTALELINVVGYPIAAPSANLSGRPSPVTAEHVIRDLMGRIDAIIDAGETF
EEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHH
FGVESTVVNILEDPPTLLRPGAYPVEEIEKVLGRKIAIPDFARGLKYSEVALAPGMKYRH
CCHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHCCCCCCCHHHHCCCCCCEEECCCCCEEE
YSPEAKLILVESVTNDYSVIANKIIEAARDISVSTNSDICIVSSIETSSYYRKLEKVKAV
CCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHEEE
LIIGSRRNLYEVAKNLFKILRDVDNIGCKTVFVEGFPETGIGLAVMNRLRKASSSIIRV
EEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]