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The map label for this gene is cpkA [H]

Identifier: 218883322

GI number: 218883322

Start: 5764

End: 6753

Strand: Direct

Name: cpkA [H]

Synonym: DKAM_0008

Alternate gene names: 218883322

Gene position: 5764-6753 (Clockwise)

Preceding gene: 218883318

Following gene: 218883323

Centisome position: 0.42

GC content: 45.76

Gene sequence:

>990_bases
TTGGAGGGTAAGAGCCATATGAAGAAAGGACTGGATACAATAGTAATAGCGTTAGGAGGAAACGCATTCCAGACCAAAGG
AGACAGAGGCGTGGCCGAGGACTATTGGAGAAATGCCTATACTGTCGCAGAACTTATAGCGAGACTCATCGAGGAAAACT
ATGGCGTCGTAGTGACGCATGGTAACGGCCCACAAGTAGGTATAATCGCGGAATGGATGAGCCTAGGGTTAAAGGAGAAG
AACATACCACCGATGCCCCTTGATGTAGCCGGTGCCATGAGTCAGGGATGGCTTGGCTACATGCTACAGCAGGCTTTATA
TAATAAGCTAGCCGAGAAGAAGCTACTTGGTTCCAAGGTAAGGGGAGTATTAACCATTATCACACAGACGCTTGTAGATA
GGAATGATCCAGCCTTCAATGATCCAACAAAGTACATAGGTCCATGGTATAGCAAGGAGGAAGCTGAAAAATTATCGAGA
GAACTTGGCTGGGTATTTAAACCAGATCCACGCGGTGGGTATAGGAGGGTTGTGCCATCCCCAGATCCCATAGGCCAGAT
TGAGATAGATGCCATTAAGATGCTAGTTGAGCAGGGATTCATCGTGATAGCTGATGGAGGCGGGGGAATACCTGTATACA
GAGATGAAAATGGCTTATTACATGGATTAGAGGGTGTGATAGATAAGGATCTCGGCGCGGAGAGAATGGCTTCGGCGTTG
AAGGCGGATATATTATTAATATTGACAGATATCGAGAAGGCATTTCTAAACTATGGAACACCAAATGCTAAACCCCTTGA
CGTGGTAAAGGTTAGCGAGGCATTAAAATACTATAGGGAAGGACACTTCAAGCCAGGGAGCATGGGTCCAAAAATACTTG
CCGGGATGAGATTCGTCCAAAACGGGGGTAAGATGGCTGTAATAGCTCATTTGAAGCAGGCTTATGAAGCGTTAAAAGGG
AATGCTGGTACAAGAATAATACCTGACTAA

Upstream 100 bases:

>100_bases
GTGGGATACATCGATTTTAATAAATAAATTTTATAATGTTATTATCCCACTAACTGTCAAGATTTAAAACGCTTCCTACG
AAACTAATATAATCATATCA

Downstream 100 bases:

>100_bases
TCATGTCCATAGTTGGTTTTAAAGAACCTATATCCTTTTTCTCCTATCTCTCATTCTACCTACTTGACTAATACTTTAAA
TTAAATGTGCTTCATATAAT

Product: carbamate kinase-like carbamoyl phosphate synthetase

Products: NA

Alternate protein names: Carbamate kinase-like carbamoylphosphate synthase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MEGKSHMKKGLDTIVIALGGNAFQTKGDRGVAEDYWRNAYTVAELIARLIEENYGVVVTHGNGPQVGIIAEWMSLGLKEK
NIPPMPLDVAGAMSQGWLGYMLQQALYNKLAEKKLLGSKVRGVLTIITQTLVDRNDPAFNDPTKYIGPWYSKEEAEKLSR
ELGWVFKPDPRGGYRRVVPSPDPIGQIEIDAIKMLVEQGFIVIADGGGGIPVYRDENGLLHGLEGVIDKDLGAERMASAL
KADILLILTDIEKAFLNYGTPNAKPLDVVKVSEALKYYREGHFKPGSMGPKILAGMRFVQNGGKMAVIAHLKQAYEALKG
NAGTRIIPD

Sequences:

>Translated_329_residues
MEGKSHMKKGLDTIVIALGGNAFQTKGDRGVAEDYWRNAYTVAELIARLIEENYGVVVTHGNGPQVGIIAEWMSLGLKEK
NIPPMPLDVAGAMSQGWLGYMLQQALYNKLAEKKLLGSKVRGVLTIITQTLVDRNDPAFNDPTKYIGPWYSKEEAEKLSR
ELGWVFKPDPRGGYRRVVPSPDPIGQIEIDAIKMLVEQGFIVIADGGGGIPVYRDENGLLHGLEGVIDKDLGAERMASAL
KADILLILTDIEKAFLNYGTPNAKPLDVVKVSEALKYYREGHFKPGSMGPKILAGMRFVQNGGKMAVIAHLKQAYEALKG
NAGTRIIPD
>Mature_329_residues
MEGKSHMKKGLDTIVIALGGNAFQTKGDRGVAEDYWRNAYTVAELIARLIEENYGVVVTHGNGPQVGIIAEWMSLGLKEK
NIPPMPLDVAGAMSQGWLGYMLQQALYNKLAEKKLLGSKVRGVLTIITQTLVDRNDPAFNDPTKYIGPWYSKEEAEKLSR
ELGWVFKPDPRGGYRRVVPSPDPIGQIEIDAIKMLVEQGFIVIADGGGGIPVYRDENGLLHGLEGVIDKDLGAERMASAL
KADILLILTDIEKAFLNYGTPNAKPLDVVKVSEALKYYREGHFKPGSMGPKILAGMRFVQNGGKMAVIAHLKQAYEALKG
NAGTRIIPD

Specific function: Unknown

COG id: COG0549

COG function: function code E; Carbamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbamate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1789238, Length=316, Percent_Identity=42.4050632911392, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1786516, Length=318, Percent_Identity=40.8805031446541, Blast_Score=214, Evalue=5e-57,
Organism=Escherichia coli, GI1786732, Length=317, Percent_Identity=40.6940063091483, Blast_Score=200, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR003964
- InterPro:   IPR023000 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.2 [H]

Molecular weight: Translated: 35973; Mature: 35973

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGKSHMKKGLDTIVIALGGNAFQTKGDRGVAEDYWRNAYTVAELIARLIEENYGVVVTH
CCCHHHHHCCCCEEEEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEC
GNGPQVGIIAEWMSLGLKEKNIPPMPLDVAGAMSQGWLGYMLQQALYNKLAEKKLLGSKV
CCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
RGVLTIITQTLVDRNDPAFNDPTKYIGPWYSKEEAEKLSRELGWVFKPDPRGGYRRVVPS
HHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCHHHHHHHHHHCCCEECCCCCCCCEECCCC
PDPIGQIEIDAIKMLVEQGFIVIADGGGGIPVYRDENGLLHGLEGVIDKDLGAERMASAL
CCCCCCCHHHHHHHHHHCCEEEEECCCCCCCEEECCCCCHHHHHHHHHCCCCHHHHHHHH
KADILLILTDIEKAFLNYGTPNAKPLDVVKVSEALKYYREGHFKPGSMGPKILAGMRFVQ
HHHHHEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
NGGKMAVIAHLKQAYEALKGNAGTRIIPD
CCCCEEHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MEGKSHMKKGLDTIVIALGGNAFQTKGDRGVAEDYWRNAYTVAELIARLIEENYGVVVTH
CCCHHHHHCCCCEEEEEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEC
GNGPQVGIIAEWMSLGLKEKNIPPMPLDVAGAMSQGWLGYMLQQALYNKLAEKKLLGSKV
CCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
RGVLTIITQTLVDRNDPAFNDPTKYIGPWYSKEEAEKLSRELGWVFKPDPRGGYRRVVPS
HHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCHHHHHHHHHHCCCEECCCCCCCCEECCCC
PDPIGQIEIDAIKMLVEQGFIVIADGGGGIPVYRDENGLLHGLEGVIDKDLGAERMASAL
CCCCCCCHHHHHHHHHHCCEEEEECCCCCCCEEECCCCCHHHHHHHHHCCCCHHHHHHHH
KADILLILTDIEKAFLNYGTPNAKPLDVVKVSEALKYYREGHFKPGSMGPKILAGMRFVQ
HHHHHEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
NGGKMAVIAHLKQAYEALKGNAGTRIIPD
CCCCEEHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11523892; 12622808 [H]