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The map label for this gene is speH [H]

Identifier: 218883317

GI number: 218883317

Start: 1393

End: 1761

Strand: Reverse

Name: speH [H]

Synonym: DKAM_0003

Alternate gene names: 218883317

Gene position: 1761-1393 (Counterclockwise)

Preceding gene: 218883319

Following gene: 218883316

Centisome position: 0.13

GC content: 42.28

Gene sequence:

>369_bases
ATGGAAGCGCTTACCATTAAGAAAGTCATAGGGAAACATGTTTACGGCGAGCTCTACGAGTGCGACCCAGGGATTTTAAT
GAACGAGAAGGATTTAGTAGAAATAGTTAAGAAGGCAGCTGAAATAGGTGGTTTCACATTACTTGATGTAAAGGCGTGGA
AGATCAACCCTGGCGTAAGCGTTGTTGGCATAGTGTTGGAGAGCCATATAAGTATTCATACGTGGCCCGAATTCGCTTTT
GCCACAGTGGATGTATATACCTGTGGCACTAAAGGCGACTCGGTTAAAGCATACAAGTATATTGTTCACGCTTTAAAAGC
CAAAAGGCATACATTAAGAGTGGTGAATAGGGACTACGAGGATAATTAA

Upstream 100 bases:

>100_bases
TTGAATTAACCTCTTCATTTTTAACTAGCTCGGCTTGCTAGGGGGGTAAAATTTATAAATAGGGAGAGGGGGATTTATTA
TTGAAGGGGAGGGGGTTGAT

Downstream 100 bases:

>100_bases
TGATTGAAACGGATATATGCGTGATTGGTGCTGGCCCAGCTGGGTTGAGCCCTCTTGTTTTTATTGGGAACAGGGATGCA
GTTATTTTCGAGGAACATAG

Product: S-adenosylmethionine decarboxylase

Products: NA

Alternate protein names: AdoMetDC; SAMDC [H]

Number of amino acids: Translated: 122; Mature: 122

Protein sequence:

>122_residues
MEALTIKKVIGKHVYGELYECDPGILMNEKDLVEIVKKAAEIGGFTLLDVKAWKINPGVSVVGIVLESHISIHTWPEFAF
ATVDVYTCGTKGDSVKAYKYIVHALKAKRHTLRVVNRDYEDN

Sequences:

>Translated_122_residues
MEALTIKKVIGKHVYGELYECDPGILMNEKDLVEIVKKAAEIGGFTLLDVKAWKINPGVSVVGIVLESHISIHTWPEFAF
ATVDVYTCGTKGDSVKAYKYIVHALKAKRHTLRVVNRDYEDN
>Mature_122_residues
MEALTIKKVIGKHVYGELYECDPGILMNEKDLVEIVKKAAEIGGFTLLDVKAWKINPGVSVVGIVLESHISIHTWPEFAF
ATVDVYTCGTKGDSVKAYKYIVHALKAKRHTLRVVNRDYEDN

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine [H]

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716 [H]

Pfam domain/function: PF02675 AdoMet_dc [H]

EC number: =4.1.1.50 [H]

Molecular weight: Translated: 13662; Mature: 13662

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEALTIKKVIGKHVYGELYECDPGILMNEKDLVEIVKKAAEIGGFTLLDVKAWKINPGVS
CCCCHHHHHHHHHHCCCEEECCCCCEECCHHHHHHHHHHHHHCCEEEEEEEEEEECCCCH
VVGIVLESHISIHTWPEFAFATVDVYTCGTKGDSVKAYKYIVHALKAKRHTLRVVNRDYE
HEEEEHHCCCEEEECCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCC
DN
CC
>Mature Secondary Structure
MEALTIKKVIGKHVYGELYECDPGILMNEKDLVEIVKKAAEIGGFTLLDVKAWKINPGVS
CCCCHHHHHHHHHHCCCEEECCCCCEECCHHHHHHHHHHHHHCCEEEEEEEEEEECCCCH
VVGIVLESHISIHTWPEFAFATVDVYTCGTKGDSVKAYKYIVHALKAKRHTLRVVNRDYE
HEEEEHHCCCEEEECCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCC
DN
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA