Click here to switch to the map view.

The map label for this gene is nagA [H]

Identifier: 218532580

GI number: 218532580

Start: 4974564

End: 4975730

Strand: Reverse

Name: nagA [H]

Synonym: Mchl_4694

Alternate gene names: 218532580

Gene position: 4975730-4974564 (Counterclockwise)

Preceding gene: 218532581

Following gene: 218532579

Centisome position: 86.12

GC content: 73.26

Gene sequence:

>1167_bases
ATGATCCCTTTGGGAACCCCTTATGATCAAGCGATCTGCGCGGACCGCGTCTTCGATGGCGAGCGGATGCTCGGCGACCG
CGCCGTCGTGCTGCGCGGCGGGCACATCGTCGACGTCACCGCCGAGCCGCCAGCGGATGTTCCCCTGGTCCGGTTGCCGG
CAGGCGCGGTGCTGGCACCGGGCTTCATCGATTGTCAGGTCAATGGCGGCGGAGGGGTGCTCCTCAACGACGATTCCAGC
GTGGCCGGCATCGCCCGGATCGCGGCGGCGCACCGGCGCGGCGGCACCACCGCCCTGCTGCCGACCCTCATCACCGACAC
GCGGCCCGCGATCCGGGCGGCCATCGCGGGCGTTGCCGCGGCGATCCAGGCGGGCGTCCCCGGCATCCTCGGCATCCACC
TCGAAGGGCCGTTCCTGAGCCCGCAGCGGATCGGCATCCATGACCCGTCCCGACTCGCCGAATTCGGCCCCGGCGACGCC
GAACTCCTGACCAGCCTGGGCGAGCACGGCCTCACCCTGGTGACGCTGGCGCCCGAGCGGGTGCCGGCCGGCGCGGTGGC
CGACCTCGTCGCCCGCGGCGCCCGCGTCTGCGCCGGGCATACGGCGGATACCGGGGACGCGATCCGGGCGGCGATGGCGG
AAGGGCTCACTGGCTTCACCCACCTGTTCAACGCCATGTCGCAGATCGGCCCGCGCGAGACCGGCGCGGTCGGCGTCGCC
CTCTCGGAGGCCGGGACTTTTGCCGGGATCATCGCCGACGGCCACCATGTCGGCGACGACCAGCTTCGGCTGGCCCTGCG
CCTCAAGGGAAGCGAGCGGCTGATGCTGGTGAGCGATGCCATGCCACCGGTCGGCGACACCCGCGCGGACGCGTCCTTCA
CCCTGTTCGGACGCCGGATCGTCCGGACCGGCGGCCGGCTCACCGGCGAGGACGGCACCCTGGCGGGCGCGGCGATCACC
ATGACGGAGGCCGTCCGCCACATGAGCACGCGCGGCGGCGCCTCCCTCGCGGAGGCCCTGGCCATGGCCTCGCTGACCCC
GGCCCGCTTCCTCGGGCTCGACACCCGGCTCGGCCGGATCGCCCCCGGCTTTGCGGCCGATCTCGTCGCGCTCTCCGCTG
ACAGGGCGGTGCTCGGCACGTGGATCGGCGGGGAACAAGCCGTCTGA

Upstream 100 bases:

>100_bases
TGATGACGAGTCCGGGTTTCGAAAGGGCGAGCCCTTTCGCGGCTCCAGGGCGGACCCCTGGGACGACATCGGGGCGCTGC
CCCGAGACCCCGCCAAAGGG

Downstream 100 bases:

>100_bases
GCCACGGTTCGCTCCCTCACGGAACCCGTCCGGGGCCGCATTTTCCGAAAGGGTTGAGAACCATGAAACTTCCGCTTCGA
CGCGGCCTCTTCATCCTGGC

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MIPLGTPYDQAICADRVFDGERMLGDRAVVLRGGHIVDVTAEPPADVPLVRLPAGAVLAPGFIDCQVNGGGGVLLNDDSS
VAGIARIAAAHRRGGTTALLPTLITDTRPAIRAAIAGVAAAIQAGVPGILGIHLEGPFLSPQRIGIHDPSRLAEFGPGDA
ELLTSLGEHGLTLVTLAPERVPAGAVADLVARGARVCAGHTADTGDAIRAAMAEGLTGFTHLFNAMSQIGPRETGAVGVA
LSEAGTFAGIIADGHHVGDDQLRLALRLKGSERLMLVSDAMPPVGDTRADASFTLFGRRIVRTGGRLTGEDGTLAGAAIT
MTEAVRHMSTRGGASLAEALAMASLTPARFLGLDTRLGRIAPGFAADLVALSADRAVLGTWIGGEQAV

Sequences:

>Translated_388_residues
MIPLGTPYDQAICADRVFDGERMLGDRAVVLRGGHIVDVTAEPPADVPLVRLPAGAVLAPGFIDCQVNGGGGVLLNDDSS
VAGIARIAAAHRRGGTTALLPTLITDTRPAIRAAIAGVAAAIQAGVPGILGIHLEGPFLSPQRIGIHDPSRLAEFGPGDA
ELLTSLGEHGLTLVTLAPERVPAGAVADLVARGARVCAGHTADTGDAIRAAMAEGLTGFTHLFNAMSQIGPRETGAVGVA
LSEAGTFAGIIADGHHVGDDQLRLALRLKGSERLMLVSDAMPPVGDTRADASFTLFGRRIVRTGGRLTGEDGTLAGAAIT
MTEAVRHMSTRGGASLAEALAMASLTPARFLGLDTRLGRIAPGFAADLVALSADRAVLGTWIGGEQAV
>Mature_388_residues
MIPLGTPYDQAICADRVFDGERMLGDRAVVLRGGHIVDVTAEPPADVPLVRLPAGAVLAPGFIDCQVNGGGGVLLNDDSS
VAGIARIAAAHRRGGTTALLPTLITDTRPAIRAAIAGVAAAIQAGVPGILGIHLEGPFLSPQRIGIHDPSRLAEFGPGDA
ELLTSLGEHGLTLVTLAPERVPAGAVADLVARGARVCAGHTADTGDAIRAAMAEGLTGFTHLFNAMSQIGPRETGAVGVA
LSEAGTFAGIIADGHHVGDDQLRLALRLKGSERLMLVSDAMPPVGDTRADASFTLFGRRIVRTGGRLTGEDGTLAGAAIT
MTEAVRHMSTRGGASLAEALAMASLTPARFLGLDTRLGRIAPGFAADLVALSADRAVLGTWIGGEQAV

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=422, Percent_Identity=34.3601895734597, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI224922791, Length=421, Percent_Identity=34.2042755344418, Blast_Score=134, Evalue=1e-31,
Organism=Escherichia coli, GI1786892, Length=385, Percent_Identity=39.2207792207792, Blast_Score=231, Evalue=6e-62,
Organism=Caenorhabditis elegans, GI17553768, Length=384, Percent_Identity=30.7291666666667, Blast_Score=131, Evalue=6e-31,
Organism=Drosophila melanogaster, GI19920392, Length=340, Percent_Identity=34.4117647058824, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI281361140, Length=354, Percent_Identity=33.3333333333333, Blast_Score=150, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 39493; Mature: 39493

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPLGTPYDQAICADRVFDGERMLGDRAVVLRGGHIVDVTAEPPADVPLVRLPAGAVLAP
CCCCCCCHHHHHHHHHHCCCHHHCCCEEEEEECCEEEEEECCCCCCCCEEEECCCCEECC
GFIDCQVNGGGGVLLNDDSSVAGIARIAAAHRRGGTTALLPTLITDTRPAIRAAIAGVAA
CEEEEEEECCCEEEECCCCCHHHHHHHHHHHHCCCCEEEHHHHHCCCCHHHHHHHHHHHH
AIQAGVPGILGIHLEGPFLSPQRIGIHDPSRLAEFGPGDAELLTSLGEHGLTLVTLAPER
HHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHCCCCEEEEEECCCC
VPAGAVADLVARGARVCAGHTADTGDAIRAAMAEGLTGFTHLFNAMSQIGPRETGAVGVA
CCCHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEE
LSEAGTFAGIIADGHHVGDDQLRLALRLKGSERLMLVSDAMPPVGDTRADASFTLFGRRI
EECCCCEEEEEECCCCCCHHHEEEEEEECCCCEEEEEECCCCCCCCCCCCCEEEHHHHHH
VRTGGRLTGEDGTLAGAAITMTEAVRHMSTRGGASLAEALAMASLTPARFLGLDTRLGRI
HHCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHCCCCHHCCC
APGFAADLVALSADRAVLGTWIGGEQAV
CCCHHHHHHHHCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MIPLGTPYDQAICADRVFDGERMLGDRAVVLRGGHIVDVTAEPPADVPLVRLPAGAVLAP
CCCCCCCHHHHHHHHHHCCCHHHCCCEEEEEECCEEEEEECCCCCCCCEEEECCCCEECC
GFIDCQVNGGGGVLLNDDSSVAGIARIAAAHRRGGTTALLPTLITDTRPAIRAAIAGVAA
CEEEEEEECCCEEEECCCCCHHHHHHHHHHHHCCCCEEEHHHHHCCCCHHHHHHHHHHHH
AIQAGVPGILGIHLEGPFLSPQRIGIHDPSRLAEFGPGDAELLTSLGEHGLTLVTLAPER
HHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHCCCCEEEEEECCCC
VPAGAVADLVARGARVCAGHTADTGDAIRAAMAEGLTGFTHLFNAMSQIGPRETGAVGVA
CCCHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEE
LSEAGTFAGIIADGHHVGDDQLRLALRLKGSERLMLVSDAMPPVGDTRADASFTLFGRRI
EECCCCEEEEEECCCCCCHHHEEEEEEECCCCEEEEEECCCCCCCCCCCCCEEEHHHHHH
VRTGGRLTGEDGTLAGAAITMTEAVRHMSTRGGASLAEALAMASLTPARFLGLDTRLGRI
HHCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHCCCCHHCCC
APGFAADLVALSADRAVLGTWIGGEQAV
CCCHHHHHHHHCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]