| Definition | Methylobacterium chloromethanicum CM4, complete genome. |
|---|---|
| Accession | NC_011757 |
| Length | 5,777,908 |
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The map label for this gene is dsbD [H]
Identifier: 218532534
GI number: 218532534
Start: 4927943
End: 4930090
Strand: Reverse
Name: dsbD [H]
Synonym: Mchl_4648
Alternate gene names: 218532534
Gene position: 4930090-4927943 (Counterclockwise)
Preceding gene: 218532535
Following gene: 218532532
Centisome position: 85.33
GC content: 73.93
Gene sequence:
>2148_bases ATGCTTCGTCTCCTCCTCGCCCTCCTCCTGACGCTTGCCGCTCCGGGCCTTGCCGGCGCGCAGGGGGCGATGACGGCGGT GAAGGCCAAGGATCTCGTGCGCGCGCGCCTCGTCGCCGAGAGCGAGGCGCTGGTGCCCGGCCGCACGGTGACGCTCGGCC TGCACATGGCGATGAAGCCGGGCTGGCACGTGTACTGGCGCAATCCCGGCGATTCCGGCCTGCCGCCGGAGATGGCGTGG CGCCTGCCCGAGGGCTTCACGGTCGGCCCGGTGCAATGGCCGGTCCCGGAGCGCATCCCGGTCCAGACCCTGATGAATTT CGGCTACGAGGGCGCCGTCACCCTGCTGGTGCCGCTCAAAGTGCCGGAGAGCGCTCGGGCCGGCGAGACGGCGCGGCTCG CCGGCACGCTCTCCTACCTCGTCTGCGAGGAGATCTGCATTCCGGGCTCGGCAGAGCTGAGCCTCGATCTGCCCGTGGCG GCCTCTGCGGAGCCGGATTCGGGGCAGGCGGCCCTGTTCGCCCGCGCCCGCGCCGCCCTTCCCGAAGCCCTGCCCGAAGC CCTGCCCGAAGCCGCGCCCGGCTCGTATCGCACGACTCGCGAAGGCGACCGGCTCGTGCTGCATCTCGACCGGCCGGGCC TCGCGGGCGTGACCGGGGCCGCCTTCTTCCCCTATGCCGAGGGCGCGCTCGACAACGCCGCGCCGCAGGATCTCGCCGTC GATGCCGCCGGCCTGCGCCTCACCCTGACGCCGGGCGATGCGGGGCAGCCGCCCGAAGCGCTCGCCGGCGTGCTCGCCCT CACCGAGGACGGCACGCGCAAGGCCTACGCGCTGGGCCCGGAACCCGCCCCCGCACCGACGGCGGCCGCGACCGTTCCCG CCGCGCCCGAGACGCCGCCCGCCCCGGCGGAAGAGGAGACCCTGACGCTGTGGAGCGCCGCGGGGCTGGCGCTCGTCGGC GGGCTCCTGCTCAACCTGATGCCCTGCGTCTTCCCGGTTCTCTCGATCAAGGTGCTGAGCCTCGTGCGGCAGGCGGGCGA ATCCACCACCCGCGTGCGGCTGCACGGGCTCGCTTACACGGCGGGCGTGCTCGCGAGCTTCCTCGGGCTGGCCGGGCTGC TGATCGCGCTGAAGGCGGGCGGCGCCGGGATCGGCTGGGGCTTCCAGCTCCAGTCGCCGGTAGTGGTGGCGCTGCTGGCC TACGGGCTGTTCGCCATGGGCCTGAGCCTGTCGGGCGCGGTGCATCTCGGCGGCGGCATCGTCGGGCTCGGCGACGGGCT GACCCGGCGGGCGGGCTACCAGGGCTCGTTCTTCACCGGCGTACTGGCGACGCTCGTCGCGACGCCCTGCACCGCGCCGT TCATGGGCGCCGCGGTGGGCTTTGCGCTGACGCAGTCGCCGCTCGCCGCGCTCACCGTGTTCGCAAGCCTCGGCCTCGGG CTCGCCCTGCCATTCCTAGGCCTGACGCTGGTCCCGCAGGCGCTGCGCCTGCTGCCGCGGCCCGGCGCCTGGATGGACGT GCTGAAGGGTGCGCTCGCCTTTCCCGTCTACGCCACGGTGGCGTGGCTCGTCTGGGTGCTGGCGCAGCAGGTCGGACCCA ACGGGCTGCTCGCAGGGCTCACCGGCCTCGTCCTCGTGGCGCTCGCCGCCTGGGCCTGGGAACGGGCGCGCGGGGCGGGC CGGCTCGGCACCGGCTTCGGCCGGGTGGCGGCCCTTGCAGCACTCGCAGCGGCGCTCGGCCTCGTCGCGGTCCTCAACGG CGACCGTGCCACCGCGCGCACCGCTCTGGCGCAGGGCGAGGAGGCCTTCACGCAGAGCCGCCTCGATGCGCTGAGAAGCG AGGGCCGCACGGTGTTCGTGGACATGACGGCGGCGTGGTGCATCACCTGCCAGGTCAACGAGCGCACGGTGCTGGCCCGC GAGGGGGTGCAGGCAGCGTTCCGGGGGGGCCAAGTGGTGTACCTGAAGGGCGACTGGACCAACCAGAACCCGGAGATCAC CCGCCTGTTGGAGCGCCACGGCCGCAGCGGCGTGCCGCTCTACCTCGTCTATCGCGGCCAGGGCGAAGCGCAGGTGCTGC CGCAGATCCTCACCGAGGGGATCGTGCTCGCGGCCATCGGGCAGAAGGACGTCGCGGCGGCGCAGTAG
Upstream 100 bases:
>100_bases CGCTCCGGCCCAACCGGCCTCTCCCCTTCGCGGTCGCGGGCTTGCCCGGGGCCGGGCGTCCTTGCGGGGAGGGGCGCCGG GCCGCTCGGAAAACAGATCG
Downstream 100 bases:
>100_bases GGCTCGATCCCGTTCAATTCATCCCCTCTCCCCGCAAGCGGGGAGAGGGGAAACCCGCGCCTCAGCCCGCGAGCTTGGCC GCGATGCCGGCCACGTGGCG
Product: thiol:disulfide interchange protein
Products: NA
Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]
Number of amino acids: Translated: 715; Mature: 715
Protein sequence:
>715_residues MLRLLLALLLTLAAPGLAGAQGAMTAVKAKDLVRARLVAESEALVPGRTVTLGLHMAMKPGWHVYWRNPGDSGLPPEMAW RLPEGFTVGPVQWPVPERIPVQTLMNFGYEGAVTLLVPLKVPESARAGETARLAGTLSYLVCEEICIPGSAELSLDLPVA ASAEPDSGQAALFARARAALPEALPEALPEAAPGSYRTTREGDRLVLHLDRPGLAGVTGAAFFPYAEGALDNAAPQDLAV DAAGLRLTLTPGDAGQPPEALAGVLALTEDGTRKAYALGPEPAPAPTAAATVPAAPETPPAPAEEETLTLWSAAGLALVG GLLLNLMPCVFPVLSIKVLSLVRQAGESTTRVRLHGLAYTAGVLASFLGLAGLLIALKAGGAGIGWGFQLQSPVVVALLA YGLFAMGLSLSGAVHLGGGIVGLGDGLTRRAGYQGSFFTGVLATLVATPCTAPFMGAAVGFALTQSPLAALTVFASLGLG LALPFLGLTLVPQALRLLPRPGAWMDVLKGALAFPVYATVAWLVWVLAQQVGPNGLLAGLTGLVLVALAAWAWERARGAG RLGTGFGRVAALAALAAALGLVAVLNGDRATARTALAQGEEAFTQSRLDALRSEGRTVFVDMTAAWCITCQVNERTVLAR EGVQAAFRGGQVVYLKGDWTNQNPEITRLLERHGRSGVPLYLVYRGQGEAQVLPQILTEGIVLAAIGQKDVAAAQ
Sequences:
>Translated_715_residues MLRLLLALLLTLAAPGLAGAQGAMTAVKAKDLVRARLVAESEALVPGRTVTLGLHMAMKPGWHVYWRNPGDSGLPPEMAW RLPEGFTVGPVQWPVPERIPVQTLMNFGYEGAVTLLVPLKVPESARAGETARLAGTLSYLVCEEICIPGSAELSLDLPVA ASAEPDSGQAALFARARAALPEALPEALPEAAPGSYRTTREGDRLVLHLDRPGLAGVTGAAFFPYAEGALDNAAPQDLAV DAAGLRLTLTPGDAGQPPEALAGVLALTEDGTRKAYALGPEPAPAPTAAATVPAAPETPPAPAEEETLTLWSAAGLALVG GLLLNLMPCVFPVLSIKVLSLVRQAGESTTRVRLHGLAYTAGVLASFLGLAGLLIALKAGGAGIGWGFQLQSPVVVALLA YGLFAMGLSLSGAVHLGGGIVGLGDGLTRRAGYQGSFFTGVLATLVATPCTAPFMGAAVGFALTQSPLAALTVFASLGLG LALPFLGLTLVPQALRLLPRPGAWMDVLKGALAFPVYATVAWLVWVLAQQVGPNGLLAGLTGLVLVALAAWAWERARGAG RLGTGFGRVAALAALAAALGLVAVLNGDRATARTALAQGEEAFTQSRLDALRSEGRTVFVDMTAAWCITCQVNERTVLAR EGVQAAFRGGQVVYLKGDWTNQNPEITRLLERHGRSGVPLYLVYRGQGEAQVLPQILTEGIVLAAIGQKDVAAAQ >Mature_715_residues MLRLLLALLLTLAAPGLAGAQGAMTAVKAKDLVRARLVAESEALVPGRTVTLGLHMAMKPGWHVYWRNPGDSGLPPEMAW RLPEGFTVGPVQWPVPERIPVQTLMNFGYEGAVTLLVPLKVPESARAGETARLAGTLSYLVCEEICIPGSAELSLDLPVA ASAEPDSGQAALFARARAALPEALPEALPEAAPGSYRTTREGDRLVLHLDRPGLAGVTGAAFFPYAEGALDNAAPQDLAV DAAGLRLTLTPGDAGQPPEALAGVLALTEDGTRKAYALGPEPAPAPTAAATVPAAPETPPAPAEEETLTLWSAAGLALVG GLLLNLMPCVFPVLSIKVLSLVRQAGESTTRVRLHGLAYTAGVLASFLGLAGLLIALKAGGAGIGWGFQLQSPVVVALLA YGLFAMGLSLSGAVHLGGGIVGLGDGLTRRAGYQGSFFTGVLATLVATPCTAPFMGAAVGFALTQSPLAALTVFASLGLG LALPFLGLTLVPQALRLLPRPGAWMDVLKGALAFPVYATVAWLVWVLAQQVGPNGLLAGLTGLVLVALAAWAWERARGAG RLGTGFGRVAALAALAAALGLVAVLNGDRATARTALAQGEEAFTQSRLDALRSEGRTVFVDMTAAWCITCQVNERTVLAR EGVQAAFRGGQVVYLKGDWTNQNPEITRLLERHGRSGVPLYLVYRGQGEAQVLPQILTEGIVLAAIGQKDVAAAQ
Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a
COG id: COG4232
COG function: function code OC; Thiol:disulfide interchange protein
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 thioredoxin domain [H]
Homologues:
Organism=Escherichia coli, GI1790578, Length=489, Percent_Identity=28.4253578732106, Blast_Score=95, Evalue=2e-20,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003834 - InterPro: IPR022910 - InterPro: IPR017936 - InterPro: IPR012336 - InterPro: IPR013766 - InterPro: IPR012335 [H]
Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]
EC number: =1.8.1.8 [H]
Molecular weight: Translated: 73761; Mature: 73761
Theoretical pI: Translated: 6.53; Mature: 6.53
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLRLLLALLLTLAAPGLAGAQGAMTAVKAKDLVRARLVAESEALVPGRTVTLGLHMAMKP CHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECC GWHVYWRNPGDSGLPPEMAWRLPEGFTVGPVQWPVPERIPVQTLMNFGYEGAVTLLVPLK CEEEEEECCCCCCCCHHHHHCCCCCCEECCCCCCCCCCCCHHHHHHCCCCCEEEEEEEEE VPESARAGETARLAGTLSYLVCEEICIPGSAELSLDLPVAASAEPDSGQAALFARARAAL CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCEECCCCCCCCCHHHHHHHHHHH PEALPEALPEAAPGSYRTTREGDRLVLHLDRPGLAGVTGAAFFPYAEGALDNAAPQDLAV HHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHCCCCCCCCCCCCCCCCEE DAAGLRLTLTPGDAGQPPEALAGVLALTEDGTRKAYALGPEPAPAPTAAATVPAAPETPP ECCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCC APAEEETLTLWSAAGLALVGGLLLNLMPCVFPVLSIKVLSLVRQAGESTTRVRLHGLAYT CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHH AGVLASFLGLAGLLIALKAGGAGIGWGFQLQSPVVVALLAYGLFAMGLSLSGAVHLGGGI HHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCEEEECCCE VGLGDGLTRRAGYQGSFFTGVLATLVATPCTAPFMGAAVGFALTQSPLAALTVFASLGLG EECCCCHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH LALPFLGLTLVPQALRLLPRPGAWMDVLKGALAFPVYATVAWLVWVLAQQVGPNGLLAGL HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH TGLVLVALAAWAWERARGAGRLGTGFGRVAALAALAAALGLVAVLNGDRATARTALAQGE HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCH EAFTQSRLDALRSEGRTVFVDMTAAWCITCQVNERTVLAREGVQAAFRGGQVVYLKGDWT HHHHHHHHHHHHHCCCEEEEEEEEEEEEEEEECCCEEEHHHCHHHHHCCCEEEEEECCCC NQNPEITRLLERHGRSGVPLYLVYRGQGEAQVLPQILTEGIVLAAIGQKDVAAAQ CCCHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHCCEEEEECCCCCCCCCC >Mature Secondary Structure MLRLLLALLLTLAAPGLAGAQGAMTAVKAKDLVRARLVAESEALVPGRTVTLGLHMAMKP CHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECC GWHVYWRNPGDSGLPPEMAWRLPEGFTVGPVQWPVPERIPVQTLMNFGYEGAVTLLVPLK CEEEEEECCCCCCCCHHHHHCCCCCCEECCCCCCCCCCCCHHHHHHCCCCCEEEEEEEEE VPESARAGETARLAGTLSYLVCEEICIPGSAELSLDLPVAASAEPDSGQAALFARARAAL CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCEECCCCCCCCCHHHHHHHHHHH PEALPEALPEAAPGSYRTTREGDRLVLHLDRPGLAGVTGAAFFPYAEGALDNAAPQDLAV HHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHCCCCCCCCCCCCCCCCEE DAAGLRLTLTPGDAGQPPEALAGVLALTEDGTRKAYALGPEPAPAPTAAATVPAAPETPP ECCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCC APAEEETLTLWSAAGLALVGGLLLNLMPCVFPVLSIKVLSLVRQAGESTTRVRLHGLAYT CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHH AGVLASFLGLAGLLIALKAGGAGIGWGFQLQSPVVVALLAYGLFAMGLSLSGAVHLGGGI HHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCEEEECCCE VGLGDGLTRRAGYQGSFFTGVLATLVATPCTAPFMGAAVGFALTQSPLAALTVFASLGLG EECCCCHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH LALPFLGLTLVPQALRLLPRPGAWMDVLKGALAFPVYATVAWLVWVLAQQVGPNGLLAGL HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH TGLVLVALAAWAWERARGAGRLGTGFGRVAALAALAAALGLVAVLNGDRATARTALAQGE HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCH EAFTQSRLDALRSEGRTVFVDMTAAWCITCQVNERTVLAREGVQAAFRGGQVVYLKGDWT HHHHHHHHHHHHHCCCEEEEEEEEEEEEEEEECCCEEEHHHCHHHHHCCCEEEEEECCCC NQNPEITRLLERHGRSGVPLYLVYRGQGEAQVLPQILTEGIVLAAIGQKDVAAAQ CCCHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHCCEEEEECCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA