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The map label for this gene is surE

Identifier: 218532489

GI number: 218532489

Start: 4880517

End: 4881281

Strand: Reverse

Name: surE

Synonym: Mchl_4603

Alternate gene names: 218532489

Gene position: 4881281-4880517 (Counterclockwise)

Preceding gene: 218532490

Following gene: 218532488

Centisome position: 84.48

GC content: 68.24

Gene sequence:

>765_bases
ATGCGCATCCTGGTCACCAACGACGACGGCATCCACGCGCCGGGCCTGGAGACGCTGGAAGGCATCGCCCGCGCGCTCAG
CGACGATGTCTGGGTGGTCGCGCCCGAGACCGATCAGTCGGGCGTGTCGCACTCGCTCTCGCTCAACGATCCGCTGCGCC
TGCGCCAAATCGGGGAAAAGCGCTTCGCGGTGAAGGGCACGCCCTCGGACTGCATCATCATGGGGGTGGCCCATATCCTC
AAGGACCACAAACCCGACCTCGTGCTCTCGGGCGTCAACCGCGGCCAGAACGTGGCCGAGGACGTGACCTATTCCGGCAC
CATCGCCGGGGCGATGGAGGGGACGATCCTCGGTATCCGCTCGATCGCGCTGAGCCAGGCCTACGGCGCGGGCGGGCGGG
CCAACCTGAAATGGGCCTGCGCCGCCACGCACGGGCCGCGGGTGATCGAGAAGATCCTGGAGATCGGCATCGAGCCCGGC
ATCCTCGTCAACGTCAACTTCCCCGATTGCGAGCCGGAAGACGTGCAGGGCGTGGCGGTCTCGGCGCAGGGCCAGCGCAA
TCAAGCGCTCCTGCAAATCGATGCCCGCCACGACGGGCGCGGCAACCCCTATTTCTGGCTCGCCTTCGCCAAGGCGCGGT
TCGAGCCCGGCAACGGCACCGATCTCAAGGCGATCGCCGAGAACCGCATCTCGGTGACGCCGCTGCGGCTCGACCTCACC
GACGAGCCGGAACTGACCCGCTTCGCCGCGGCGTTCCGGGCGTGA

Upstream 100 bases:

>100_bases
TGATGGAGAACTACCAGAACCCCGACGGCAGCGTCACGATCCCGTCGGCGCTCCAGCCCTACATGGGCGGCCTCACCCGG
ATCGAGGGACCGAAGAACTG

Downstream 100 bases:

>100_bases
GCGGGGGCGGCCGTCCGGGCCCTCATGCCGCCTGAGGCCGGAGAGCCCGACGAACGGGCTGATCGGCTGTCCGCGGGGCT
GGCGGAGGCGACCGGCAACG

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MRILVTNDDGIHAPGLETLEGIARALSDDVWVVAPETDQSGVSHSLSLNDPLRLRQIGEKRFAVKGTPSDCIIMGVAHIL
KDHKPDLVLSGVNRGQNVAEDVTYSGTIAGAMEGTILGIRSIALSQAYGAGGRANLKWACAATHGPRVIEKILEIGIEPG
ILVNVNFPDCEPEDVQGVAVSAQGQRNQALLQIDARHDGRGNPYFWLAFAKARFEPGNGTDLKAIAENRISVTPLRLDLT
DEPELTRFAAAFRA

Sequences:

>Translated_254_residues
MRILVTNDDGIHAPGLETLEGIARALSDDVWVVAPETDQSGVSHSLSLNDPLRLRQIGEKRFAVKGTPSDCIIMGVAHIL
KDHKPDLVLSGVNRGQNVAEDVTYSGTIAGAMEGTILGIRSIALSQAYGAGGRANLKWACAATHGPRVIEKILEIGIEPG
ILVNVNFPDCEPEDVQGVAVSAQGQRNQALLQIDARHDGRGNPYFWLAFAKARFEPGNGTDLKAIAENRISVTPLRLDLT
DEPELTRFAAAFRA
>Mature_254_residues
MRILVTNDDGIHAPGLETLEGIARALSDDVWVVAPETDQSGVSHSLSLNDPLRLRQIGEKRFAVKGTPSDCIIMGVAHIL
KDHKPDLVLSGVNRGQNVAEDVTYSGTIAGAMEGTILGIRSIALSQAYGAGGRANLKWACAATHGPRVIEKILEIGIEPG
ILVNVNFPDCEPEDVQGVAVSAQGQRNQALLQIDARHDGRGNPYFWLAFAKARFEPGNGTDLKAIAENRISVTPLRLDLT
DEPELTRFAAAFRA

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=241, Percent_Identity=39.0041493775934, Blast_Score=163, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_METC4 (B7KPY4)

Other databases:

- EMBL:   CP001298
- RefSeq:   YP_002423305.1
- ProteinModelPortal:   B7KPY4
- SMR:   B7KPY4
- GeneID:   7117999
- GenomeReviews:   CP001298_GR
- KEGG:   mch:Mchl_4603
- HOGENOM:   HBG600532
- OMA:   SINIPIK
- ProtClustDB:   PRK00346
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 27263; Mature: 27263

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVTNDDGIHAPGLETLEGIARALSDDVWVVAPETDQSGVSHSLSLNDPLRLRQIGEK
CEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCEEEECCCCCHHHHHHCCC
RFAVKGTPSDCIIMGVAHILKDHKPDLVLSGVNRGQNVAEDVTYSGTIAGAMEGTILGIR
EEEEECCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHCEECCEEECCCCCEEEHHH
SIALSQAYGAGGRANLKWACAATHGPRVIEKILEIGIEPGILVNVNFPDCEPEDVQGVAV
HHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEE
SAQGQRNQALLQIDARHDGRGNPYFWLAFAKARFEPGNGTDLKAIAENRISVTPLRLDLT
ECCCCCCCEEEEEECCCCCCCCCEEEEEEEEEEECCCCCCCHHHHHCCCEEEEEEEEECC
DEPELTRFAAAFRA
CCCHHHHHHHHHCC
>Mature Secondary Structure
MRILVTNDDGIHAPGLETLEGIARALSDDVWVVAPETDQSGVSHSLSLNDPLRLRQIGEK
CEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCEEEECCCCCHHHHHHCCC
RFAVKGTPSDCIIMGVAHILKDHKPDLVLSGVNRGQNVAEDVTYSGTIAGAMEGTILGIR
EEEEECCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHCEECCEEECCCCCEEEHHH
SIALSQAYGAGGRANLKWACAATHGPRVIEKILEIGIEPGILVNVNFPDCEPEDVQGVAV
HHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEE
SAQGQRNQALLQIDARHDGRGNPYFWLAFAKARFEPGNGTDLKAIAENRISVTPLRLDLT
ECCCCCCCEEEEEECCCCCCCCCEEEEEEEEEEECCCCCCCHHHHHCCCEEEEEEEEECC
DEPELTRFAAAFRA
CCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA