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The map label for this gene is crtB [H]

Identifier: 218532481

GI number: 218532481

Start: 4872131

End: 4873027

Strand: Reverse

Name: crtB [H]

Synonym: Mchl_4595

Alternate gene names: 218532481

Gene position: 4873027-4872131 (Counterclockwise)

Preceding gene: 218532482

Following gene: 218532479

Centisome position: 84.34

GC content: 73.47

Gene sequence:

>897_bases
ATGACGCGCCCCGAGACCCGAACCGAGACGAGCCCGGAGGCCGGCAACGGCGGACTCGCCTTCGCCTTCCGGCATTGCGA
GGAACTGGTGCGCGAGAGCGACCCGGATCGCTACTTCGCGGCCCTGTTCGCGCCCGCCGCCTTCCGGCCGCACCTCTTCG
CGCTCTCCGCGTTCAGCCTGACCATCGCCCGCGTCCGCGAGGCGGCCTCGAACCCGATGGCGGGGGAGATCCGCTTGCAA
TGGTGGCGCGACGCGCTCCAGGGGGAGGCGCGCGGCGACGTCCGGGCCAATCCCGTCGCCGCGGCTCTGGATGATGCGAT
CGTCACGCGCCGCCTCGGGCGCCAGCCCTTCGTCGATCTGATCGATGCCCGCGTCTTCGACCTCTACGACGACCCGATGC
CGCGGGTGAACGATCTGGAGGGCTATTGCGGCGAGACCGCCTCGGCGCTGATCCGCCTTTCCGGGCTGGTGCTCGCCGAT
GGGGCCGAGCCGGGTGGCGCGGCGGCCGCCGGCCATGCGGGCGTCGCCTACGGGATCACCGGCCTGTTGCGGGCATTGCC
GTGGCACGCGCGTCAGGGACAGGTCTACCTGCCCGGTGACCTGCTGCGCCAGAACGGGGTCACGCGTGAGGACATCGTCT
CGGGCCGGGGCGGGCCGGGCCTCGTGCGCACCTGCGCCGAATTGCGGGCGCTGGCACGGCGCCACCTCGCCGCCTACGAG
GCGGCCCGCGGCACCATCGCTCCGGCGGCCCGTCCCGCCTTCCTGCCGACGGCGCTGGTCGAGCCCTATCTCGCGGCGAT
GGAGCGAGCCGGCTACGATCCGCTCAACAGCGTGATCGAGATCCCCCGCTGGCGCCGCCTGTGGCGGCTGTGGCGGGCGG
CGCGCACGGGGCGATAG

Upstream 100 bases:

>100_bases
TGGCTCTAGGTCCTTGTTTTGTCGCGCTTTCTTTCGACGGACCGGCATCCACTTCGTCGGAAAGCGCTTTAAGTTCCGAA
CGCCGCGTGAGCCCCGCTCC

Downstream 100 bases:

>100_bases
AGACGTTTCACACACTTATAGAAGCTCCTCCCCGCGAAGGGGAGGAGCTCGATGGGGCGAGGCGTCAGCGCGCCTTCTTC
GTCAGCTTCTGAGCGATCTC

Product: Squalene/phytoene synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MTRPETRTETSPEAGNGGLAFAFRHCEELVRESDPDRYFAALFAPAAFRPHLFALSAFSLTIARVREAASNPMAGEIRLQ
WWRDALQGEARGDVRANPVAAALDDAIVTRRLGRQPFVDLIDARVFDLYDDPMPRVNDLEGYCGETASALIRLSGLVLAD
GAEPGGAAAAGHAGVAYGITGLLRALPWHARQGQVYLPGDLLRQNGVTREDIVSGRGGPGLVRTCAELRALARRHLAAYE
AARGTIAPAARPAFLPTALVEPYLAAMERAGYDPLNSVIEIPRWRRLWRLWRAARTGR

Sequences:

>Translated_298_residues
MTRPETRTETSPEAGNGGLAFAFRHCEELVRESDPDRYFAALFAPAAFRPHLFALSAFSLTIARVREAASNPMAGEIRLQ
WWRDALQGEARGDVRANPVAAALDDAIVTRRLGRQPFVDLIDARVFDLYDDPMPRVNDLEGYCGETASALIRLSGLVLAD
GAEPGGAAAAGHAGVAYGITGLLRALPWHARQGQVYLPGDLLRQNGVTREDIVSGRGGPGLVRTCAELRALARRHLAAYE
AARGTIAPAARPAFLPTALVEPYLAAMERAGYDPLNSVIEIPRWRRLWRLWRAARTGR
>Mature_297_residues
TRPETRTETSPEAGNGGLAFAFRHCEELVRESDPDRYFAALFAPAAFRPHLFALSAFSLTIARVREAASNPMAGEIRLQW
WRDALQGEARGDVRANPVAAALDDAIVTRRLGRQPFVDLIDARVFDLYDDPMPRVNDLEGYCGETASALIRLSGLVLADG
AEPGGAAAAGHAGVAYGITGLLRALPWHARQGQVYLPGDLLRQNGVTREDIVSGRGGPGLVRTCAELRALARRHLAAYEA
ARGTIAPAARPAFLPTALVEPYLAAMERAGYDPLNSVIEIPRWRRLWRLWRAARTGR

Specific function: Catalyzes the reaction from prephytoene diphosphate to phytoene [H]

COG id: COG1562

COG function: function code I; Phytoene/squalene synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phytoene/squalene synthase family [H]

Homologues:

Organism=Homo sapiens, GI124517691, Length=257, Percent_Identity=28.7937743190661, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI25150675, Length=265, Percent_Identity=27.9245283018868, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24641447, Length=283, Percent_Identity=27.208480565371, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002060
- InterPro:   IPR019845
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00494 SQS_PSY [H]

EC number: =2.5.1.32 [H]

Molecular weight: Translated: 32488; Mature: 32357

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPETRTETSPEAGNGGLAFAFRHCEELVRESDPDRYFAALFAPAAFRPHLFALSAFSL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHH
TIARVREAASNPMAGEIRLQWWRDALQGEARGDVRANPVAAALDDAIVTRRLGRQPFVDL
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHH
IDARVFDLYDDPMPRVNDLEGYCGETASALIRLSGLVLADGAEPGGAAAAGHAGVAYGIT
HHHHHHHHCCCCCCCCCCCCHHCCHHHHHHHHHHCEEEECCCCCCCCCCCCCCHHHHHHH
GLLRALPWHARQGQVYLPGDLLRQNGVTREDIVSGRGGPGLVRTCAELRALARRHLAAYE
HHHHHCCCCCCCCCEECCHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
AARGTIAPAARPAFLPTALVEPYLAAMERAGYDPLNSVIEIPRWRRLWRLWRAARTGR
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TRPETRTETSPEAGNGGLAFAFRHCEELVRESDPDRYFAALFAPAAFRPHLFALSAFSL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHH
TIARVREAASNPMAGEIRLQWWRDALQGEARGDVRANPVAAALDDAIVTRRLGRQPFVDL
HHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHH
IDARVFDLYDDPMPRVNDLEGYCGETASALIRLSGLVLADGAEPGGAAAAGHAGVAYGIT
HHHHHHHHCCCCCCCCCCCCHHCCHHHHHHHHHHCEEEECCCCCCCCCCCCCCHHHHHHH
GLLRALPWHARQGQVYLPGDLLRQNGVTREDIVSGRGGPGLVRTCAELRALARRHLAAYE
HHHHHCCCCCCCCCEECCHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
AARGTIAPAARPAFLPTALVEPYLAAMERAGYDPLNSVIEIPRWRRLWRLWRAARTGR
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA