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The map label for this gene is exuT [H]

Identifier: 218532457

GI number: 218532457

Start: 4838775

End: 4840076

Strand: Reverse

Name: exuT [H]

Synonym: Mchl_4569

Alternate gene names: 218532457

Gene position: 4840076-4838775 (Counterclockwise)

Preceding gene: 218532458

Following gene: 218532454

Centisome position: 83.77

GC content: 67.43

Gene sequence:

>1302_bases
ATGATCACGATCCCACGCCGCGTGACGGCGCCGGGCATGGTGCTGTTCCTGCTCTGCCTGATGTACTTCATCACCTATGT
CGACCGGGTCAACGTCGGCACCGCCGGCCCGGCGATCAAAGGTGAACTCGGCCTCAGCAACACCGAACTGGGCCTCATCT
TCTCGGCCTTCGCCTACCCCTACGCGGTGTTCCAGATCATCGGCGGCGCGATGGCCGACAAATGGGGCGCGCGGCGCACC
CTGTTCATCTGCGGCCTGATCTGGGCGGCGGCGACGGTGGCGACCGGCTTCGTCGGCGGCGTGGTCTCGCTGTTCCTGGC
CCGCTTCGCTCTCGGCTTCGGCGAGGGCGCCACCTTCCCCACCGCCACGCGGGCGATGCAGTCCTGGGTCGCCAAGGACC
AGCGCGGCTTCGCGCAGGGCATCACCCACTCGTTCGCCCGCTTCGGCAACGCGATCACGCCGCCGCTCGTGGTGCTGATG
ATGGCCTATGTCGGCTGGCGCGGCGCCTTCGTCGTGCTCGGCATCGTCAGCTTCGCCTGGGTGCTGGTCTGGGTGTACTA
CTACCGGGACGACCCGCGCGAGCATAAGAGCGTCACGAACGAGGATCTGGAACGGCTGGCGATCCGCGACCGGACGGCCA
AGCCGGCCGCCAAACCGCCGGTGCCGTGGCGCCGGCTGATCCCGCGCATGGCCCCCGTGACGCTGACCTATTTCTGCTAC
GGCTGGTCGCTGTGGCTCTACCTCAACTGGCTGCCCTCCTTCTTCAAGGACGGCTACGGCCTCGACATCAAGAACTCGGC
CCTGTTCGCCTCGGGCGTGTTCTTTGCGGGCGTGGTCGGCGACACGCTCGGCGGCGTGGTCTCCGACCGCATCCTGAAGA
AGACCGGTGACCTGCAGAAGGCGCGCCGCAACGTGATCTGCCTCGGCATGCTGGGCGCCGCCGCCTGCCTCGCCGGCGTG
TTCTTCACCAAGGACCTCACCCTGGTGGCGCTGCTGCTCAGCGGCGGCTTCTTCTTCCTCGAACTGGTCATCGGGCCGAT
CTGGTCGGTACCGATGGATATCGCCCCGCAATATGCCGGCACCGCGAGCGGGCTGATGAACTTCGGCTCGGCATTTGCCG
CGATCGTCTCGCCGCTCACCTTCGGCCTAATCGTGGATCTTACCGGCAATTGGATCCTGCCGTTTGCCGGGTCGGTCGGC
CTGCTGCTTCTGGGCGCGGGCCTCGCCTTCACCATGCACCCCGAGCGCCCGTTCGAGGATGAACCGGCGCCCCTGACCCC
GCGGGTGGTGCCAGCGGAGTAG

Upstream 100 bases:

>100_bases
TCGACGGCTGATCTTTTCCCGAACGCCCACGCCTCGGGCCAAGCCGCGCGTCAGATGCGGAGCCCGGGGCGATTGCTCAT
AAAAACTGGAGGAAGCCCCG

Downstream 100 bases:

>100_bases
ATCCGTCCCGTCGCCGCGCGCTCCCCGCGGCGACGGTTCAGGGTAGGGGAAAGCGGCGCTGAAGGTCCGCCAGCATCTCG
ACCGCCTCGTTCGAGATGCC

Product: major facilitator superfamily MFS_1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MITIPRRVTAPGMVLFLLCLMYFITYVDRVNVGTAGPAIKGELGLSNTELGLIFSAFAYPYAVFQIIGGAMADKWGARRT
LFICGLIWAAATVATGFVGGVVSLFLARFALGFGEGATFPTATRAMQSWVAKDQRGFAQGITHSFARFGNAITPPLVVLM
MAYVGWRGAFVVLGIVSFAWVLVWVYYYRDDPREHKSVTNEDLERLAIRDRTAKPAAKPPVPWRRLIPRMAPVTLTYFCY
GWSLWLYLNWLPSFFKDGYGLDIKNSALFASGVFFAGVVGDTLGGVVSDRILKKTGDLQKARRNVICLGMLGAAACLAGV
FFTKDLTLVALLLSGGFFFLELVIGPIWSVPMDIAPQYAGTASGLMNFGSAFAAIVSPLTFGLIVDLTGNWILPFAGSVG
LLLLGAGLAFTMHPERPFEDEPAPLTPRVVPAE

Sequences:

>Translated_433_residues
MITIPRRVTAPGMVLFLLCLMYFITYVDRVNVGTAGPAIKGELGLSNTELGLIFSAFAYPYAVFQIIGGAMADKWGARRT
LFICGLIWAAATVATGFVGGVVSLFLARFALGFGEGATFPTATRAMQSWVAKDQRGFAQGITHSFARFGNAITPPLVVLM
MAYVGWRGAFVVLGIVSFAWVLVWVYYYRDDPREHKSVTNEDLERLAIRDRTAKPAAKPPVPWRRLIPRMAPVTLTYFCY
GWSLWLYLNWLPSFFKDGYGLDIKNSALFASGVFFAGVVGDTLGGVVSDRILKKTGDLQKARRNVICLGMLGAAACLAGV
FFTKDLTLVALLLSGGFFFLELVIGPIWSVPMDIAPQYAGTASGLMNFGSAFAAIVSPLTFGLIVDLTGNWILPFAGSVG
LLLLGAGLAFTMHPERPFEDEPAPLTPRVVPAE
>Mature_433_residues
MITIPRRVTAPGMVLFLLCLMYFITYVDRVNVGTAGPAIKGELGLSNTELGLIFSAFAYPYAVFQIIGGAMADKWGARRT
LFICGLIWAAATVATGFVGGVVSLFLARFALGFGEGATFPTATRAMQSWVAKDQRGFAQGITHSFARFGNAITPPLVVLM
MAYVGWRGAFVVLGIVSFAWVLVWVYYYRDDPREHKSVTNEDLERLAIRDRTAKPAAKPPVPWRRLIPRMAPVTLTYFCY
GWSLWLYLNWLPSFFKDGYGLDIKNSALFASGVFFAGVVGDTLGGVVSDRILKKTGDLQKARRNVICLGMLGAAACLAGV
FFTKDLTLVALLLSGGFFFLELVIGPIWSVPMDIAPQYAGTASGLMNFGSAFAAIVSPLTFGLIVDLTGNWILPFAGSVG
LLLLGAGLAFTMHPERPFEDEPAPLTPRVVPAE

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=369, Percent_Identity=27.6422764227642, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI9966811, Length=409, Percent_Identity=24.9388753056235, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI9945322, Length=363, Percent_Identity=25.8953168044077, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI154350196, Length=387, Percent_Identity=23.5142118863049, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI21322234, Length=351, Percent_Identity=24.7863247863248, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI148743791, Length=346, Percent_Identity=22.8323699421965, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI87082320, Length=403, Percent_Identity=30.7692307692308, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1789152, Length=412, Percent_Identity=27.4271844660194, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI2367379, Length=418, Percent_Identity=27.2727272727273, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI1789515, Length=394, Percent_Identity=30.4568527918782, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI2367193, Length=425, Percent_Identity=27.5294117647059, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1788573, Length=291, Percent_Identity=26.4604810996564, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17552542, Length=358, Percent_Identity=28.7709497206704, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17535049, Length=403, Percent_Identity=24.5657568238213, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI115533556, Length=371, Percent_Identity=26.6846361185984, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI115533554, Length=371, Percent_Identity=26.6846361185984, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17554148, Length=374, Percent_Identity=23.7967914438503, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI25151055, Length=365, Percent_Identity=24.9315068493151, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17570335, Length=371, Percent_Identity=25.0673854447439, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17554962, Length=344, Percent_Identity=22.3837209302326, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI193205400, Length=390, Percent_Identity=23.3333333333333, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71991453, Length=382, Percent_Identity=21.7277486910995, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71991448, Length=382, Percent_Identity=21.7277486910995, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71997452, Length=397, Percent_Identity=22.6700251889169, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17563754, Length=374, Percent_Identity=24.331550802139, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560030, Length=325, Percent_Identity=20, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25145964, Length=374, Percent_Identity=22.4598930481283, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17557432, Length=255, Percent_Identity=22.3529411764706, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI115534564, Length=255, Percent_Identity=22.3529411764706, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17569727, Length=348, Percent_Identity=22.1264367816092, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI45550460, Length=458, Percent_Identity=25.764192139738, Blast_Score=124, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24655255, Length=370, Percent_Identity=26.2162162162162, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24654215, Length=407, Percent_Identity=24.3243243243243, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI19922400, Length=407, Percent_Identity=25.0614250614251, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24583789, Length=418, Percent_Identity=24.1626794258373, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24658674, Length=425, Percent_Identity=24, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24641682, Length=439, Percent_Identity=23.4624145785877, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24584153, Length=387, Percent_Identity=25.5813953488372, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24639764, Length=398, Percent_Identity=22.1105527638191, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI28573299, Length=395, Percent_Identity=25.0632911392405, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI19920686, Length=411, Percent_Identity=22.8710462287105, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24655271, Length=458, Percent_Identity=23.3624454148472, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI28573708, Length=385, Percent_Identity=25.7142857142857, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI28573707, Length=385, Percent_Identity=25.7142857142857, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI20130135, Length=458, Percent_Identity=23.3624454148472, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24658658, Length=399, Percent_Identity=23.8095238095238, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI20130167, Length=405, Percent_Identity=22.962962962963, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI62484226, Length=431, Percent_Identity=24.3619489559165, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24658666, Length=405, Percent_Identity=23.2098765432099, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24580790, Length=400, Percent_Identity=23.25, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24648416, Length=428, Percent_Identity=24.7663551401869, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21356189, Length=428, Percent_Identity=24.7663551401869, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI45550495, Length=431, Percent_Identity=21.8097447795824, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24658689, Length=455, Percent_Identity=22.6373626373626, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI20129235, Length=339, Percent_Identity=26.2536873156342, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24658696, Length=385, Percent_Identity=23.6363636363636, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281361682, Length=343, Percent_Identity=20.6997084548105, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI45552797, Length=393, Percent_Identity=22.64631043257, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI45550364, Length=418, Percent_Identity=23.2057416267943, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24653727, Length=416, Percent_Identity=20.1923076923077, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46961; Mature: 46961

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIPRRVTAPGMVLFLLCLMYFITYVDRVNVGTAGPAIKGELGLSNTELGLIFSAFAYP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
YAVFQIIGGAMADKWGARRTLFICGLIWAAATVATGFVGGVVSLFLARFALGFGEGATFP
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TATRAMQSWVAKDQRGFAQGITHSFARFGNAITPPLVVLMMAYVGWRGAFVVLGIVSFAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
VLVWVYYYRDDPREHKSVTNEDLERLAIRDRTAKPAAKPPVPWRRLIPRMAPVTLTYFCY
HHHHHHHHCCCCHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHH
GWSLWLYLNWLPSFFKDGYGLDIKNSALFASGVFFAGVVGDTLGGVVSDRILKKTGDLQK
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
ARRNVICLGMLGAAACLAGVFFTKDLTLVALLLSGGFFFLELVIGPIWSVPMDIAPQYAG
HHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHCCCCCCC
TASGLMNFGSAFAAIVSPLTFGLIVDLTGNWILPFAGSVGLLLLGAGLAFTMHPERPFED
HHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEECCCCHHHHHHHHCCCEEEECCCCCCCC
EPAPLTPRVVPAE
CCCCCCCCCCCCC
>Mature Secondary Structure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CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]