Click here to switch to the map view.

The map label for this gene is yciR [C]

Identifier: 218532290

GI number: 218532290

Start: 4652883

End: 4654574

Strand: Reverse

Name: yciR [C]

Synonym: Mchl_4402

Alternate gene names: 218532290

Gene position: 4654574-4652883 (Counterclockwise)

Preceding gene: 218532291

Following gene: 218532289

Centisome position: 80.56

GC content: 72.34

Gene sequence:

>1692_bases
ATGTCCGCCCTCGCCGCTCCGTCGCTGTCGATCGCCCTGCCGTTCGAGGCGGCGCTGGCCGAGATGGCCGCGCCCCTGCT
CCTGCTCGATGCGGGCGGCAGCGTCGTCTTCGCCAATGCCCACGCGGCGGCCTTGCTCGCCTGCGCCGAACCGGTCGGCC
TTCCCCTCACCGCCCTGCTGGTGCCCTTCGGCGCCGCGGAGCCGGAGGCCGAGCCCATCCTAGAGGCTGTGCGCGCCGCC
CGCCCCGTCCGGGCGCGGCTCACCCTCGGCGGCGACCGCCGCGTCGAGGCGGCGCTGGCGCCGCTCTCGGCCGGCGGCTT
CGCCCTCACCTTCGAGGACGTGACCGAGCAACTCCGCGGCGCGGCCCTGGCCCGGCAGGAGCCGCTCACCGGCCTGTGCA
ACCGCGTCGGCCTGCACGACCGCCTCGACGCGGCGCTGACCGAGGCGGCCCGGACGGGGGCACCGCTCGCGGTGCTGATG
CTCGACCTCGATCGGTTCAAGACGGTCAACGACACCCTCGGGCATCCGGTCGGCGATGCGCTCCTGCGCAAGGTCGCCGA
GCGCCTGCGCCGGGCCACCCGCAGCGGGGATCTGGTCGCACGGCTCGGCGGCGACGAGTTCGCCATCCTTCAAGTCGATC
CCCAAGTTGGACCCCATGCTGGCGTCGAGCAGCCGCACGCGGCCGAGGCGCTGGCACGCCGCCTCGTCGATCTCGTCGGG
CGCACCTACGTCGTCGATGGCCACATGCTCAATGTCGGCGTCAGCGTCGGCGTCGCCATCGCCCCCGCCGACGGCCAGAA
CGCCGACGACCTGCTGAAACACGCCGACCTCGCGCTCTACCGGGCCAAGGCCGCGGGCCGGGGCACCTACCGCTTCTTCG
AGCCGGCGATGAACGCGCAGATGCAGGCGCGCCGCGGCCTGGAGATCGACCTGCGCCGGGCAATGGCCCTCAAGCAGTTC
GACCTCGCCTTCCAGCCGCAAATCCAACTGGAGAGCGGGGACGTGACGGGCTTCGAGGCGCTGCTGCGCTGGAACCACCC
CGAGCGCGGACCGGTGTCGCCGGCCCTGTTCATTCCGTTGGCCGAGGAGATCGGCGTCATCGTCGGCATTGGCGAGTGGG
TGTTGCGCACCGCCTGCCGCGAGGCGGCGCGCTGGCCGCACCCCGCATCGATCGCCGTGAACCTCTCGCCCGTGCAGTTC
CGCGGCGGCCGGCTGGTCGAGACGGTGACGAACGTGCTGGCCCAGACCGACCTCGACCCGGCCCGGCTGGAACTGGAGAT
CACCGAAGGCGCGCTCCTCGAGAACACCGACAGCGTGCTCGACGTGCTGAACGGCCTGCGCGCGCTCGGCGTGAAGATCT
CCATGGACGATTTCGGCACCGGCTACTCGTCCTTGAGCTACCTGCAGAAATTCCCCTTCGACAAGATCAAGATCGACCAG
TCCTTCGTCCGCGGCATGGAGGGCAATGCCGAGTGCGGGGCGATCGTGCGGGCCATCGCCCGGCTCGGCGCCAGCCTCGG
CATGCGCACCACCGCCGAAGGGGTCGAGACGGCGACGCAGCTCGACGCCATCCGCGCCGAGGGCTGCACCGAGGTCCAGG
GCTACCTGACCGGACGCCCGATGCCGGCCGCCCAGGCCGCCGCCCTGTTGTCCGCCTCGCCCGCTCCCTCGCCCTCGACC
TTGCCCGCCTGA

Upstream 100 bases:

>100_bases
GCTCCGGCGCATCCCGGCTTTAAGCATCCGTTGAGAGGAAAGCAGGCCTATAGGTGGGCCGCCCAGGTGGGGCGGCCTCC
ATAGGACGCTGTCCGGCCGC

Downstream 100 bases:

>100_bases
TCCAGGAGCCCGCCGAATGAACCCGAAAGACCTGCGCCGCCTCGTCTACTACAGCCGCAACCGGGTCGCCGGTGCCCCCG
CGGCAATGGACGAGACGATC

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 563; Mature: 562

Protein sequence:

>563_residues
MSALAAPSLSIALPFEAALAEMAAPLLLLDAGGSVVFANAHAAALLACAEPVGLPLTALLVPFGAAEPEAEPILEAVRAA
RPVRARLTLGGDRRVEAALAPLSAGGFALTFEDVTEQLRGAALARQEPLTGLCNRVGLHDRLDAALTEAARTGAPLAVLM
LDLDRFKTVNDTLGHPVGDALLRKVAERLRRATRSGDLVARLGGDEFAILQVDPQVGPHAGVEQPHAAEALARRLVDLVG
RTYVVDGHMLNVGVSVGVAIAPADGQNADDLLKHADLALYRAKAAGRGTYRFFEPAMNAQMQARRGLEIDLRRAMALKQF
DLAFQPQIQLESGDVTGFEALLRWNHPERGPVSPALFIPLAEEIGVIVGIGEWVLRTACREAARWPHPASIAVNLSPVQF
RGGRLVETVTNVLAQTDLDPARLELEITEGALLENTDSVLDVLNGLRALGVKISMDDFGTGYSSLSYLQKFPFDKIKIDQ
SFVRGMEGNAECGAIVRAIARLGASLGMRTTAEGVETATQLDAIRAEGCTEVQGYLTGRPMPAAQAAALLSASPAPSPST
LPA

Sequences:

>Translated_563_residues
MSALAAPSLSIALPFEAALAEMAAPLLLLDAGGSVVFANAHAAALLACAEPVGLPLTALLVPFGAAEPEAEPILEAVRAA
RPVRARLTLGGDRRVEAALAPLSAGGFALTFEDVTEQLRGAALARQEPLTGLCNRVGLHDRLDAALTEAARTGAPLAVLM
LDLDRFKTVNDTLGHPVGDALLRKVAERLRRATRSGDLVARLGGDEFAILQVDPQVGPHAGVEQPHAAEALARRLVDLVG
RTYVVDGHMLNVGVSVGVAIAPADGQNADDLLKHADLALYRAKAAGRGTYRFFEPAMNAQMQARRGLEIDLRRAMALKQF
DLAFQPQIQLESGDVTGFEALLRWNHPERGPVSPALFIPLAEEIGVIVGIGEWVLRTACREAARWPHPASIAVNLSPVQF
RGGRLVETVTNVLAQTDLDPARLELEITEGALLENTDSVLDVLNGLRALGVKISMDDFGTGYSSLSYLQKFPFDKIKIDQ
SFVRGMEGNAECGAIVRAIARLGASLGMRTTAEGVETATQLDAIRAEGCTEVQGYLTGRPMPAAQAAALLSASPAPSPST
LPA
>Mature_562_residues
SALAAPSLSIALPFEAALAEMAAPLLLLDAGGSVVFANAHAAALLACAEPVGLPLTALLVPFGAAEPEAEPILEAVRAAR
PVRARLTLGGDRRVEAALAPLSAGGFALTFEDVTEQLRGAALARQEPLTGLCNRVGLHDRLDAALTEAARTGAPLAVLML
DLDRFKTVNDTLGHPVGDALLRKVAERLRRATRSGDLVARLGGDEFAILQVDPQVGPHAGVEQPHAAEALARRLVDLVGR
TYVVDGHMLNVGVSVGVAIAPADGQNADDLLKHADLALYRAKAAGRGTYRFFEPAMNAQMQARRGLEIDLRRAMALKQFD
LAFQPQIQLESGDVTGFEALLRWNHPERGPVSPALFIPLAEEIGVIVGIGEWVLRTACREAARWPHPASIAVNLSPVQFR
GGRLVETVTNVLAQTDLDPARLELEITEGALLENTDSVLDVLNGLRALGVKISMDDFGTGYSSLSYLQKFPFDKIKIDQS
FVRGMEGNAECGAIVRAIARLGASLGMRTTAEGVETATQLDAIRAEGCTEVQGYLTGRPMPAAQAAALLSASPAPSPSTL
PA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=438, Percent_Identity=36.5296803652968, Blast_Score=280, Evalue=2e-76,
Organism=Escherichia coli, GI87081921, Length=458, Percent_Identity=34.2794759825328, Blast_Score=265, Evalue=7e-72,
Organism=Escherichia coli, GI226510982, Length=421, Percent_Identity=28.5035629453682, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1790496, Length=248, Percent_Identity=33.4677419354839, Blast_Score=146, Evalue=4e-36,
Organism=Escherichia coli, GI87081980, Length=251, Percent_Identity=35.0597609561753, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1787055, Length=300, Percent_Identity=30.6666666666667, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI87081845, Length=251, Percent_Identity=34.6613545816733, Blast_Score=138, Evalue=9e-34,
Organism=Escherichia coli, GI1788381, Length=550, Percent_Identity=26.7272727272727, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1788502, Length=265, Percent_Identity=30.5660377358491, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1786507, Length=266, Percent_Identity=30.8270676691729, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI87081743, Length=235, Percent_Identity=30.6382978723404, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1788849, Length=235, Percent_Identity=35.3191489361702, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87082096, Length=235, Percent_Identity=30.6382978723404, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1787262, Length=172, Percent_Identity=33.7209302325581, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI145693134, Length=188, Percent_Identity=33.5106382978723, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87081977, Length=193, Percent_Identity=30.0518134715026, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786584, Length=280, Percent_Identity=27.5, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87081881, Length=210, Percent_Identity=31.4285714285714, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1787802, Length=173, Percent_Identity=34.1040462427746, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87081974, Length=157, Percent_Identity=30.5732484076433, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787816, Length=173, Percent_Identity=35.2601156069364, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788956, Length=191, Percent_Identity=31.413612565445, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1787410, Length=150, Percent_Identity=27.3333333333333, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1789650, Length=429, Percent_Identity=20.7459207459207, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI87082007, Length=167, Percent_Identity=29.940119760479, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 59440; Mature: 59309

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALAAPSLSIALPFEAALAEMAAPLLLLDAGGSVVFANAHAAALLACAEPVGLPLTALL
CCCCCCCCCEEECCHHHHHHHHCCCEEEEECCCCEEEECCHHHHHHHHCCCCCCCHHHHH
VPFGAAEPEAEPILEAVRAARPVRARLTLGGDRRVEAALAPLSAGGFALTFEDVTEQLRG
HCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHCCCCCCCEEEEHHHHHHHHHH
AALARQEPLTGLCNRVGLHDRLDAALTEAARTGAPLAVLMLDLDRFKTVNDTLGHPVGDA
HHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHCCCHHHH
LLRKVAERLRRATRSGDLVARLGGDEFAILQVDPQVGPHAGVEQPHAAEALARRLVDLVG
HHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHC
RTYVVDGHMLNVGVSVGVAIAPADGQNADDLLKHADLALYRAKAAGRGTYRFFEPAMNAQ
CEEEECCEEEEECEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCHH
MQARRGLEIDLRRAMALKQFDLAFQPQIQLESGDVTGFEALLRWNHPERGPVSPALFIPL
HHHHCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCEEEEEE
AEEIGVIVGIGEWVLRTACREAARWPHPASIAVNLSPVQFRGGRLVETVTNVLAQTDLDP
HHHCCEEEECHHHHHHHHHHHHHCCCCCCEEEEECCCEEECCCCHHHHHHHHHHHCCCCH
ARLELEITEGALLENTDSVLDVLNGLRALGVKISMDDFGTGYSSLSYLQKFPFDKIKIDQ
HEEEEEEECCCHHCCHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHCCCCCEEECH
SFVRGMEGNAECGAIVRAIARLGASLGMRTTAEGVETATQLDAIRAEGCTEVQGYLTGRP
HHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHEECCCC
MPAAQAAALLSASPAPSPSTLPA
CCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SALAAPSLSIALPFEAALAEMAAPLLLLDAGGSVVFANAHAAALLACAEPVGLPLTALL
CCCCCCCCEEECCHHHHHHHHCCCEEEEECCCCEEEECCHHHHHHHHCCCCCCCHHHHH
VPFGAAEPEAEPILEAVRAARPVRARLTLGGDRRVEAALAPLSAGGFALTFEDVTEQLRG
HCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHCCCCCCCEEEEHHHHHHHHHH
AALARQEPLTGLCNRVGLHDRLDAALTEAARTGAPLAVLMLDLDRFKTVNDTLGHPVGDA
HHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHCCCHHHH
LLRKVAERLRRATRSGDLVARLGGDEFAILQVDPQVGPHAGVEQPHAAEALARRLVDLVG
HHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHC
RTYVVDGHMLNVGVSVGVAIAPADGQNADDLLKHADLALYRAKAAGRGTYRFFEPAMNAQ
CEEEECCEEEEECEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCHH
MQARRGLEIDLRRAMALKQFDLAFQPQIQLESGDVTGFEALLRWNHPERGPVSPALFIPL
HHHHCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCEEEEEE
AEEIGVIVGIGEWVLRTACREAARWPHPASIAVNLSPVQFRGGRLVETVTNVLAQTDLDP
HHHCCEEEECHHHHHHHHHHHHHCCCCCCEEEEECCCEEECCCCHHHHHHHHHHHCCCCH
ARLELEITEGALLENTDSVLDVLNGLRALGVKISMDDFGTGYSSLSYLQKFPFDKIKIDQ
HEEEEEEECCCHHCCHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHCCCCCEEECH
SFVRGMEGNAECGAIVRAIARLGASLGMRTTAEGVETATQLDAIRAEGCTEVQGYLTGRP
HHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHEECCCC
MPAAQAAALLSASPAPSPSTLPA
CCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]