Click here to switch to the map view.

The map label for this gene is degP [C]

Identifier: 218532143

GI number: 218532143

Start: 4485457

End: 4486431

Strand: Reverse

Name: degP [C]

Synonym: Mchl_4255

Alternate gene names: 218532143

Gene position: 4486431-4485457 (Counterclockwise)

Preceding gene: 218532146

Following gene: 218532141

Centisome position: 77.65

GC content: 73.54

Gene sequence:

>975_bases
ATGTCCGCGCACGGCGAATTCAGGATTCCGGCCGCCCTGCAGCCGAAGGCCGGCGACTACGCCTACGATCTGGAGCGGGC
GCTGACCTCGGTCGTGTCCCTCTCCTCGCGGGTGCCGGCGGAGGCCTTCACGGCGGAGACGCTCGGCACCGAGCGGGCGG
GCAACGGCGTGGTGATCCGCGAGGACGGGCTGGTGCTCACCATCGGCTACCTCGTGCTGGAGGCCGAGAGCGTCTGGCTC
ACCACCCATGACGGGCGCTCGGTGCCGGCCCACGTCGTCGGCTATGACGGGGAGACCGGCTTCGGCCTCGTCCAGGCGCT
CGGCCGCCTCGGCCTGCCCGCCCTGAGGCTCGGGCGCTCGGATACGCTGAAGGTTGGCGAGCGGGCGGTGATCGCGGGGG
CGGGCGGACGCTCGCACAGCCTCGCGGTCGAACTCGTCGCCCGGCAGGAATTCGCCGGCTACTGGGAGTATGTCCTCGAC
GACGCCCTGTTCACCACTCCTGCCCATCCCCACTGGGGCGGCACCGCCCTGATCGGCCCCGACGGCGCGCTGGTCGGCAT
CGGCTCGCTTCAGCTCCAGCAGGGCGGCACGGGGGCGGGCCGGGCGATCAACATGGTCGTGCCGATCGAACTCCTGCCGC
CGATCCTGACCGATCTCGAGACCCGCGGCCGGGCCGACCGCCCGCCCCGCCCCTGGCTCGGCCTCTACGCCACGGAGACC
GAGGACGGCGTCGTGGTGATGGGGACCGCCGACAGGGGTCCGGCGGAGGCCGCCGACCTGCGCGCGGGCGACGTGCTGAC
CGAGGTGGCGGGCGAGCCGGTCGCCGACTTGGCCGGCTTCTTCCGGCAGGTCTGGGCCCTCGGGGAGGCGGGGGTGCGCG
TCCCCCTCACGGTCAACCGGGACGGGCGCCTGACCCGGCTCGCGCTGACCTCGGTCGATCGCGAGCGGTTCCTGATCGGG
CCGAAGCTGCACTGA

Upstream 100 bases:

>100_bases
TTGCGGACGGGAGACGGATGCGGCCGCCCCGGCGGCCGCCGTTTCCGCGGAAGTCGGTCTACGGGCGGCGGCGGAGTGGG
GCGCAGGGAAATCGCAGAAC

Downstream 100 bases:

>100_bases
CCCGTGCTGTGTGCCCGGCAGCCTAGATCACCCCTGGATCACACGATGAGGAAATCCGTGTGGTCCAGGGCAGCGTGGTT
ATCCAGCACCGCGACCAGGA

Product: PDZ/DHR/GLGF domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MSAHGEFRIPAALQPKAGDYAYDLERALTSVVSLSSRVPAEAFTAETLGTERAGNGVVIREDGLVLTIGYLVLEAESVWL
TTHDGRSVPAHVVGYDGETGFGLVQALGRLGLPALRLGRSDTLKVGERAVIAGAGGRSHSLAVELVARQEFAGYWEYVLD
DALFTTPAHPHWGGTALIGPDGALVGIGSLQLQQGGTGAGRAINMVVPIELLPPILTDLETRGRADRPPRPWLGLYATET
EDGVVVMGTADRGPAEAADLRAGDVLTEVAGEPVADLAGFFRQVWALGEAGVRVPLTVNRDGRLTRLALTSVDRERFLIG
PKLH

Sequences:

>Translated_324_residues
MSAHGEFRIPAALQPKAGDYAYDLERALTSVVSLSSRVPAEAFTAETLGTERAGNGVVIREDGLVLTIGYLVLEAESVWL
TTHDGRSVPAHVVGYDGETGFGLVQALGRLGLPALRLGRSDTLKVGERAVIAGAGGRSHSLAVELVARQEFAGYWEYVLD
DALFTTPAHPHWGGTALIGPDGALVGIGSLQLQQGGTGAGRAINMVVPIELLPPILTDLETRGRADRPPRPWLGLYATET
EDGVVVMGTADRGPAEAADLRAGDVLTEVAGEPVADLAGFFRQVWALGEAGVRVPLTVNRDGRLTRLALTSVDRERFLIG
PKLH
>Mature_323_residues
SAHGEFRIPAALQPKAGDYAYDLERALTSVVSLSSRVPAEAFTAETLGTERAGNGVVIREDGLVLTIGYLVLEAESVWLT
THDGRSVPAHVVGYDGETGFGLVQALGRLGLPALRLGRSDTLKVGERAVIAGAGGRSHSLAVELVARQEFAGYWEYVLDD
ALFTTPAHPHWGGTALIGPDGALVGIGSLQLQQGGTGAGRAINMVVPIELLPPILTDLETRGRADRPPRPWLGLYATETE
DGVVVMGTADRGPAEAADLRAGDVLTEVAGEPVADLAGFFRQVWALGEAGVRVPLTVNRDGRLTRLALTSVDRERFLIGP
KLH

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786356, Length=275, Percent_Identity=26.9090909090909, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789629, Length=315, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 34249; Mature: 34118

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAHGEFRIPAALQPKAGDYAYDLERALTSVVSLSSRVPAEAFTAETLGTERAGNGVVIR
CCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEEEE
EDGLVLTIGYLVLEAESVWLTTHDGRSVPAHVVGYDGETGFGLVQALGRLGLPALRLGRS
CCCEEEEEEEEEEEECEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHCCCCHHHCCCC
DTLKVGERAVIAGAGGRSHSLAVELVARQEFAGYWEYVLDDALFTTPAHPHWGGTALIGP
CCEECCCEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECC
DGALVGIGSLQLQQGGTGAGRAINMVVPIELLPPILTDLETRGRADRPPRPWLGLYATET
CCCEEEECEEEEECCCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECC
EDGVVVMGTADRGPAEAADLRAGDVLTEVAGEPVADLAGFFRQVWALGEAGVRVPLTVNR
CCCEEEEECCCCCCCCHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEECC
DGRLTRLALTSVDRERFLIGPKLH
CCCEEEEEEECCCCCCEEECCCCC
>Mature Secondary Structure 
SAHGEFRIPAALQPKAGDYAYDLERALTSVVSLSSRVPAEAFTAETLGTERAGNGVVIR
CCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEEEE
EDGLVLTIGYLVLEAESVWLTTHDGRSVPAHVVGYDGETGFGLVQALGRLGLPALRLGRS
CCCEEEEEEEEEEEECEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHCCCCHHHCCCC
DTLKVGERAVIAGAGGRSHSLAVELVARQEFAGYWEYVLDDALFTTPAHPHWGGTALIGP
CCEECCCEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECC
DGALVGIGSLQLQQGGTGAGRAINMVVPIELLPPILTDLETRGRADRPPRPWLGLYATET
CCCEEEECEEEEECCCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECC
EDGVVVMGTADRGPAEAADLRAGDVLTEVAGEPVADLAGFFRQVWALGEAGVRVPLTVNR
CCCEEEEECCCCCCCCHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEECC
DGRLTRLALTSVDRERFLIGPKLH
CCCEEEEEEECCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA