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The map label for this gene is tadA [H]

Identifier: 218532085

GI number: 218532085

Start: 4405860

End: 4406303

Strand: Reverse

Name: tadA [H]

Synonym: Mchl_4179

Alternate gene names: 218532085

Gene position: 4406303-4405860 (Counterclockwise)

Preceding gene: 218532086

Following gene: 218532084

Centisome position: 76.26

GC content: 73.87

Gene sequence:

>444_bases
ATGCCCGATTTCCTCGACCTCGCCTTCGCCGCCGCCCGCGAGGCCGCGGCTCTGGGCGAGGTACCGGTCGGCGCGGCCGT
GGTGCGGGACGGGGCCGTGCTCGCGGTTGCCGGCAACCGGCCGCGCACGCTGTGCGACCCCACGGCCCATGCCGAGATCC
TGGCGATCCGCGCCGCCTGCGCCGCGCTAAGTGACGAGCGGCTCACCGGCTGCGACCTCTACGTGACCCTGGAGCCCTGC
CCGATGTGCGCGGGCGCGATCGCCTTCGCCCGTATCCGCCGGCTCTACTACGCCGCCTCCGACCCCAAGGGCGGCGGCGT
CGAGCACGGCCCTCGCGTGTTCAACCAGCCGACCTGCCACCACGCGCCGGAGGTCTATTCGGGCTTTCGCGAGGGCGAGG
CGGCGGGCCTGCTCAGGGATTTTTTCGCCGAGCGGCGGGGGTGA

Upstream 100 bases:

>100_bases
AAGCGCATCGACTGGCCGGACGGGTTCTTCCGCAGCGATATCGGCGGCCGGGAGGTCGCCCGCGAAGCAGCTTCCAAGGG
CGACTGATGAAGGGCGACTG

Downstream 100 bases:

>100_bases
GCCGGGAGAGGCGTCGGGGCGGAGCGTCGAACCGCGGCTGCAGGCGGCGCGTTCGATCCTTCGTCCCCGTACCGCACCGG
AGCCCCCTCCCATGGTCCCG

Product: CMP/dCMP deaminase zinc-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MPDFLDLAFAAAREAAALGEVPVGAAVVRDGAVLAVAGNRPRTLCDPTAHAEILAIRAACAALSDERLTGCDLYVTLEPC
PMCAGAIAFARIRRLYYAASDPKGGGVEHGPRVFNQPTCHHAPEVYSGFREGEAAGLLRDFFAERRG

Sequences:

>Translated_147_residues
MPDFLDLAFAAAREAAALGEVPVGAAVVRDGAVLAVAGNRPRTLCDPTAHAEILAIRAACAALSDERLTGCDLYVTLEPC
PMCAGAIAFARIRRLYYAASDPKGGGVEHGPRVFNQPTCHHAPEVYSGFREGEAAGLLRDFFAERRG
>Mature_146_residues
PDFLDLAFAAAREAAALGEVPVGAAVVRDGAVLAVAGNRPRTLCDPTAHAEILAIRAACAALSDERLTGCDLYVTLEPCP
MCAGAIAFARIRRLYYAASDPKGGGVEHGPRVFNQPTCHHAPEVYSGFREGEAAGLLRDFFAERRG

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Escherichia coli, GI145693172, Length=143, Percent_Identity=41.958041958042, Blast_Score=108, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17554608, Length=115, Percent_Identity=36.5217391304348, Blast_Score=89, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17541138, Length=111, Percent_Identity=40.5405405405405, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17555996, Length=96, Percent_Identity=38.5416666666667, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21355527, Length=148, Percent_Identity=33.1081081081081, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 15527; Mature: 15396

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDFLDLAFAAAREAAALGEVPVGAAVVRDGAVLAVAGNRPRTLCDPTAHAEILAIRAAC
CCCHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHHH
AALSDERLTGCDLYVTLEPCPMCAGAIAFARIRRLYYAASDPKGGGVEHGPRVFNQPTCH
HHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
HAPEVYSGFREGEAAGLLRDFFAERRG
CCHHHHHHHCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PDFLDLAFAAAREAAALGEVPVGAAVVRDGAVLAVAGNRPRTLCDPTAHAEILAIRAAC
CCHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHHH
AALSDERLTGCDLYVTLEPCPMCAGAIAFARIRRLYYAASDPKGGGVEHGPRVFNQPTCH
HHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
HAPEVYSGFREGEAAGLLRDFFAERRG
CCHHHHHHHCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]