Click here to switch to the map view.

The map label for this gene is ade3 [H]

Identifier: 218531671

GI number: 218531671

Start: 3950146

End: 3951951

Strand: Reverse

Name: ade3 [H]

Synonym: Mchl_3740

Alternate gene names: 218531671

Gene position: 3951951-3950146 (Counterclockwise)

Preceding gene: 218531672

Following gene: 218531669

Centisome position: 68.4

GC content: 72.15

Gene sequence:

>1806_bases
ATGACTGCCCAACCCCTCACCCGCTTCGCCGTCGCGCCGCTGGCCCAGATGACGCGGCGCCTCGCCGATGTCGCCGCAGG
CCGCGCCGAGCCCGATCTGGTGATCACGGGTGCGCGGGTGCTCTCGACCTATTCCGAGCGCATCCTGCCGGACCGCGAGA
TCTGGATCGCGGGCGGGCGCATCGCCGCGGTGAAGCCGTCGGGCCACCATCGGGGCGGCGCCCCGCGCTACGATGCGCGC
GGCGGCCTGATCGCGCCGGGGCTGGTCGATCCGCATCTGCATATCGAGAGCAGCATGGTGACGGCCTGCGCCTACGCCGA
GGCCGCGCTGATCAACGGCACCACCACGATCGTCTGCGACAGCCACGAGATCGGCAACGTGCTGGACGTGAACGGCGTGG
AATGGATGCTGGAGGATGCCCGCGCGGCGCCCCTCAACATCTTCCTGACCGTGCCGAGCACGGTGCCCGCCACCACGCCG
GATCTCGAGACCGCGGGCGGCGACCTGACGGCGGAGAAGATCGGCGCCCTGTTCGATGCCTGGCCCGAGGCGATCGGGCT
CGGCGAGAAGATGGATTTCGTCGCGGTGGCCAGCGGGGACGAGCGGGCGCACGCCATCATCCGCGCCGCGCTGGAGCGGG
GCCGCCCGGTCTCCGGCCATGTCTACGGCCGCGACTTCGTGGCGGCCTACGCCGCGAGCGGCGTCACCGACACCCACGAG
GCCGTGGATGCCGACATCGCCGACGATCTCCTGGAAGCCGGCCTCTGGATCTTTCTGCGCGGGGGGCCGCCGACCACGCC
CTGGCACTCGCTGCCCAAAGCCATCGGCACCGTGACCGAGTACGGCGCCGCCTGGAAGCGGGTCTGCGCCTGCACCGACG
ACCGCGACGCCGACGACCTGCTGGCGTTCGGCCTCGACTGGGTGGTGCGCGAGGCGGTGGCGCGCGGCATCCCGAAACCC
GCGGCCTGGGCCATGGGCTCTTTGCATGGGGCCACCCGCTACGGCCTCGACGGCGAGGTCGGCGGCCTCGGCGGCGGGCG
CCGGGCCGACCTCGTGCTCCTGAACGACGATCTCGTGCCGCAGGCGACGTGGTATGGCGGGCAACAGGTGGTGGAGGATC
GCCGGCCGACGCCGCGTCTCGAAGAGGCCCTGGCCCGGCCCTACCGCTACCCGGCCCCCGCCTACGCCACGGTCCGCCTG
CCCGACCCCGTTCCCGCCCTGATCCCGGCCCTGCCCGCTGGGCCCTGCACGGTCAACGCGATCCGCACCACGCTGCCGGG
CATCGAGCTGACGCATGAGCGCGTCTCGCTCACCCCCGGCGCGGATTGGGCGGCGACGCTCGCCGCGCACGATCTCTGCC
ACGTCGCGGTGGTGGAACGGCACGGCCGTTCCGGCGGCGTCGCCCACGGGCTGCTCTCGGCCTTCGGCTTGAAGCGCGGT
GCGGTGGCGAGCAGCGTCGGCCACGATTCGCACAACCTCATCGTCGCGGGGCTGAACGAGGCCGACATGCGGGTGGCCCT
CGACGCCATCGCCACGCATCAAGGCGGCGTCTGTGTCGTCGAGGAGGGCCAAGTCGTCGCGATGGTGGCGCTGCCGGTGG
CGGGGCTCCTCTCCGACAAGCGCGTGGGCGCGGTGGCGGATGAGGTGAAGGCGCTCAAGCGCGCCTGGGAGCGGGCCGGC
TGCAGCATTCCCTATATGGGCTTCAACCTGATCCCGCTCGCGGTGATCCCGCAGATCCGTATCACCGACAAGGGCGTGGT
GCTGGTGCCGGAGATGCGCTCGGTGCCGTTGTTCGAGGCGGCTTGA

Upstream 100 bases:

>100_bases
GGACGAACAGGACTAACCGTCACCGGCGGCTGCGCCCGGCCTTCCTTTCGTGGCACGATGCCTGCGCGCCGTGCCCGAGA
GCCACGTAAGGAAGGCCCCG

Downstream 100 bases:

>100_bases
ACGCGGCGCTCCGCCGAGCCCCTCTCCCCGCAAGCGGGGCGAGGCCGTCCTGCACCCCGTCGTGCAGGACGGTAGCGAAG
GCGCAGCCGTAGCGAGCGTG

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase 3; Adenine aminase 3 [H]

Number of amino acids: Translated: 601; Mature: 600

Protein sequence:

>601_residues
MTAQPLTRFAVAPLAQMTRRLADVAAGRAEPDLVITGARVLSTYSERILPDREIWIAGGRIAAVKPSGHHRGGAPRYDAR
GGLIAPGLVDPHLHIESSMVTACAYAEAALINGTTTIVCDSHEIGNVLDVNGVEWMLEDARAAPLNIFLTVPSTVPATTP
DLETAGGDLTAEKIGALFDAWPEAIGLGEKMDFVAVASGDERAHAIIRAALERGRPVSGHVYGRDFVAAYAASGVTDTHE
AVDADIADDLLEAGLWIFLRGGPPTTPWHSLPKAIGTVTEYGAAWKRVCACTDDRDADDLLAFGLDWVVREAVARGIPKP
AAWAMGSLHGATRYGLDGEVGGLGGGRRADLVLLNDDLVPQATWYGGQQVVEDRRPTPRLEEALARPYRYPAPAYATVRL
PDPVPALIPALPAGPCTVNAIRTTLPGIELTHERVSLTPGADWAATLAAHDLCHVAVVERHGRSGGVAHGLLSAFGLKRG
AVASSVGHDSHNLIVAGLNEADMRVALDAIATHQGGVCVVEEGQVVAMVALPVAGLLSDKRVGAVADEVKALKRAWERAG
CSIPYMGFNLIPLAVIPQIRITDKGVVLVPEMRSVPLFEAA

Sequences:

>Translated_601_residues
MTAQPLTRFAVAPLAQMTRRLADVAAGRAEPDLVITGARVLSTYSERILPDREIWIAGGRIAAVKPSGHHRGGAPRYDAR
GGLIAPGLVDPHLHIESSMVTACAYAEAALINGTTTIVCDSHEIGNVLDVNGVEWMLEDARAAPLNIFLTVPSTVPATTP
DLETAGGDLTAEKIGALFDAWPEAIGLGEKMDFVAVASGDERAHAIIRAALERGRPVSGHVYGRDFVAAYAASGVTDTHE
AVDADIADDLLEAGLWIFLRGGPPTTPWHSLPKAIGTVTEYGAAWKRVCACTDDRDADDLLAFGLDWVVREAVARGIPKP
AAWAMGSLHGATRYGLDGEVGGLGGGRRADLVLLNDDLVPQATWYGGQQVVEDRRPTPRLEEALARPYRYPAPAYATVRL
PDPVPALIPALPAGPCTVNAIRTTLPGIELTHERVSLTPGADWAATLAAHDLCHVAVVERHGRSGGVAHGLLSAFGLKRG
AVASSVGHDSHNLIVAGLNEADMRVALDAIATHQGGVCVVEEGQVVAMVALPVAGLLSDKRVGAVADEVKALKRAWERAG
CSIPYMGFNLIPLAVIPQIRITDKGVVLVPEMRSVPLFEAA
>Mature_600_residues
TAQPLTRFAVAPLAQMTRRLADVAAGRAEPDLVITGARVLSTYSERILPDREIWIAGGRIAAVKPSGHHRGGAPRYDARG
GLIAPGLVDPHLHIESSMVTACAYAEAALINGTTTIVCDSHEIGNVLDVNGVEWMLEDARAAPLNIFLTVPSTVPATTPD
LETAGGDLTAEKIGALFDAWPEAIGLGEKMDFVAVASGDERAHAIIRAALERGRPVSGHVYGRDFVAAYAASGVTDTHEA
VDADIADDLLEAGLWIFLRGGPPTTPWHSLPKAIGTVTEYGAAWKRVCACTDDRDADDLLAFGLDWVVREAVARGIPKPA
AWAMGSLHGATRYGLDGEVGGLGGGRRADLVLLNDDLVPQATWYGGQQVVEDRRPTPRLEEALARPYRYPAPAYATVRLP
DPVPALIPALPAGPCTVNAIRTTLPGIELTHERVSLTPGADWAATLAAHDLCHVAVVERHGRSGGVAHGLLSAFGLKRGA
VASSVGHDSHNLIVAGLNEADMRVALDAIATHQGGVCVVEEGQVVAMVALPVAGLLSDKRVGAVADEVKALKRAWERAGC
SIPYMGFNLIPLAVIPQIRITDKGVVLVPEMRSVPLFEAA

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family [H]

Homologues:

Organism=Escherichia coli, GI1790098, Length=583, Percent_Identity=31.9039451114923, Blast_Score=219, Evalue=5e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.2 [H]

Molecular weight: Translated: 63353; Mature: 63222

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAQPLTRFAVAPLAQMTRRLADVAAGRAEPDLVITGARVLSTYSERILPDREIWIAGGR
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHCCCCCEEEEECCE
IAAVKPSGHHRGGAPRYDARGGLIAPGLVDPHLHIESSMVTACAYAEAALINGTTTIVCD
EEEECCCCCCCCCCCCCCCCCCEECCCCCCCCEEECHHHHHHHHHHHHEEECCCEEEEEC
SHEIGNVLDVNGVEWMLEDARAAPLNIFLTVPSTVPATTPDLETAGGDLTAEKIGALFDA
CCCCCCEEECCCHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
WPEAIGLGEKMDFVAVASGDERAHAIIRAALERGRPVSGHVYGRDFVAAYAASGVTDTHE
HHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHCCCCCHHH
AVDADIADDLLEAGLWIFLRGGPPTTPWHSLPKAIGTVTEYGAAWKRVCACTDDRDADDL
HHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
LAFGLDWVVREAVARGIPKPAAWAMGSLHGATRYGLDGEVGGLGGGRRADLVLLNDDLVP
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCC
QATWYGGQQVVEDRRPTPRLEEALARPYRYPAPAYATVRLPDPVPALIPALPAGPCTVNA
CCCCCCCHHHHHCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHCCCCCCCCCHHH
IRTTLPGIELTHERVSLTPGADWAATLAAHDLCHVAVVERHGRSGGVAHGLLSAFGLKRG
HHHHCCCCEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCC
AVASSVGHDSHNLIVAGLNEADMRVALDAIATHQGGVCVVEEGQVVAMVALPVAGLLSDK
CHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCEEEEEEHHHHHHHCCC
RVGAVADEVKALKRAWERAGCSIPYMGFNLIPLAVIPQIRITDKGVVLVPEMRSVPLFEA
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCEEEECCCEEEECCCCCCCCCCC
A
C
>Mature Secondary Structure 
TAQPLTRFAVAPLAQMTRRLADVAAGRAEPDLVITGARVLSTYSERILPDREIWIAGGR
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHCCCCCEEEEECCE
IAAVKPSGHHRGGAPRYDARGGLIAPGLVDPHLHIESSMVTACAYAEAALINGTTTIVCD
EEEECCCCCCCCCCCCCCCCCCEECCCCCCCCEEECHHHHHHHHHHHHEEECCCEEEEEC
SHEIGNVLDVNGVEWMLEDARAAPLNIFLTVPSTVPATTPDLETAGGDLTAEKIGALFDA
CCCCCCEEECCCHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
WPEAIGLGEKMDFVAVASGDERAHAIIRAALERGRPVSGHVYGRDFVAAYAASGVTDTHE
HHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHCCCCCHHH
AVDADIADDLLEAGLWIFLRGGPPTTPWHSLPKAIGTVTEYGAAWKRVCACTDDRDADDL
HHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
LAFGLDWVVREAVARGIPKPAAWAMGSLHGATRYGLDGEVGGLGGGRRADLVLLNDDLVP
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCC
QATWYGGQQVVEDRRPTPRLEEALARPYRYPAPAYATVRLPDPVPALIPALPAGPCTVNA
CCCCCCCHHHHHCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHCCCCCCCCCHHH
IRTTLPGIELTHERVSLTPGADWAATLAAHDLCHVAVVERHGRSGGVAHGLLSAFGLKRG
HHHHCCCCEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCC
AVASSVGHDSHNLIVAGLNEADMRVALDAIATHQGGVCVVEEGQVVAMVALPVAGLLSDK
CHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCEEEEEEHHHHHHHCCC
RVGAVADEVKALKRAWERAGCSIPYMGFNLIPLAVIPQIRITDKGVVLVPEMRSVPLFEA
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCEEEECCCEEEECCCCCCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA