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The map label for this gene is ctaC [H]

Identifier: 218531519

GI number: 218531519

Start: 3775954

End: 3776793

Strand: Reverse

Name: ctaC [H]

Synonym: Mchl_3587

Alternate gene names: 218531519

Gene position: 3776793-3775954 (Counterclockwise)

Preceding gene: 218531521

Following gene: 218531518

Centisome position: 65.37

GC content: 66.07

Gene sequence:

>840_bases
ATGCGGACGACGCAGGCGCAACATCGGTCATCGTGGGGGCTCGCCGCGTTCGGCGCTCTCCTCGGTTCGTCCTCCTCCGC
TCTCGCGGCCGGTATCGGTCAGCCCGAGCCGTGGCAGATGAGCCGTCAGATACCGGTCACGGCCGAGGCCGCTGACCTCC
TCAACTTCGAGCACGGGCTGCACTGGATCGCCTTCGCGATCTCGGTCTTCGTTCTCGTTCTCATTCTCTACTGCATCTTC
AAGTTCAACGAGAAGACGAATCCGACGCCGTCGCGCACCACGCACAACACGGCGATCGAGGTAGCCTGGACCATCATCCC
GGTCCTGATCCTCGTGGCGGTGGCGATCCCCTCGTTCCGCACCCTGCGCACGCAGCTCTCGGACCCGAAGGCCGACCTCG
TGGTCAAGGTCGTCGGCCACGCGTGGTACTGGTCCTACGTCTACCCGGCCGAGGGCGACAAGGGCGGCTTCACCTTCGAC
GCGAACGTCGATGAGGAGCAGCAGCCCAAGCTGCTCGCGACCGACAACGACATGGTCATCCCGGTCGGCAAGGTCGTGAA
GGTGCAGGTCACCTCCGACGACGTCATCCACTCCTGGGCGATCCCCTCCTTCGGCGGCAAGATCGACGCCATCCCCGGAC
GTCTGAACCAGTGGTGGTTCAAGGCCGACCGCGAGGGCACCTATCACGGCCAGTGCTCCGAGCTGTGCGGCGCCCGTCAC
GCCTACATGCCGATCACCGTGCGCGTGGTCAGCGAGCAGGCCTACGCCGACTGGCTGACCGAGGCGAAGACCAAGTACGC
CGCGATCGACAACGGCGCGCGCCTCGCGGACGCCCGCTGA

Upstream 100 bases:

>100_bases
CAAGGCCCGCGATACGATCGGGCAGTTCTGGGATTTGCGACGCTCGTCGGCAAATTCAAGGGCAAACAAACCATAGGCAC
CAGGGGAGCCAAGCGGGGAC

Downstream 100 bases:

>100_bases
CGCTTCTCCGGGCCGGCACGCGCCGGCCGGATCTCCCTTCGCCAGAGGCGACAGACATCTGATTAAGGCAAGGATCGATG
GCCACCGCCACAGCACATGC

Product: cytochrome C oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MRTTQAQHRSSWGLAAFGALLGSSSSALAAGIGQPEPWQMSRQIPVTAEAADLLNFEHGLHWIAFAISVFVLVLILYCIF
KFNEKTNPTPSRTTHNTAIEVAWTIIPVLILVAVAIPSFRTLRTQLSDPKADLVVKVVGHAWYWSYVYPAEGDKGGFTFD
ANVDEEQQPKLLATDNDMVIPVGKVVKVQVTSDDVIHSWAIPSFGGKIDAIPGRLNQWWFKADREGTYHGQCSELCGARH
AYMPITVRVVSEQAYADWLTEAKTKYAAIDNGARLADAR

Sequences:

>Translated_279_residues
MRTTQAQHRSSWGLAAFGALLGSSSSALAAGIGQPEPWQMSRQIPVTAEAADLLNFEHGLHWIAFAISVFVLVLILYCIF
KFNEKTNPTPSRTTHNTAIEVAWTIIPVLILVAVAIPSFRTLRTQLSDPKADLVVKVVGHAWYWSYVYPAEGDKGGFTFD
ANVDEEQQPKLLATDNDMVIPVGKVVKVQVTSDDVIHSWAIPSFGGKIDAIPGRLNQWWFKADREGTYHGQCSELCGARH
AYMPITVRVVSEQAYADWLTEAKTKYAAIDNGARLADAR
>Mature_279_residues
MRTTQAQHRSSWGLAAFGALLGSSSSALAAGIGQPEPWQMSRQIPVTAEAADLLNFEHGLHWIAFAISVFVLVLILYCIF
KFNEKTNPTPSRTTHNTAIEVAWTIIPVLILVAVAIPSFRTLRTQLSDPKADLVVKVVGHAWYWSYVYPAEGDKGGFTFD
ANVDEEQQPKLLATDNDMVIPVGKVVKVQVTSDDVIHSWAIPSFGGKIDAIPGRLNQWWFKADREGTYHGQCSELCGARH
AYMPITVRVVSEQAYADWLTEAKTKYAAIDNGARLADAR

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=164, Percent_Identity=43.9024390243902, Blast_Score=154, Evalue=1e-37,
Organism=Escherichia coli, GI1786635, Length=270, Percent_Identity=24.0740740740741, Blast_Score=68, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6226540, Length=194, Percent_Identity=41.7525773195876, Blast_Score=144, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 30770; Mature: 30770

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTTQAQHRSSWGLAAFGALLGSSSSALAAGIGQPEPWQMSRQIPVTAEAADLLNFEHGL
CCCCCCHHHCCCCHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
HWIAFAISVFVLVLILYCIFKFNEKTNPTPSRTTHNTAIEVAWTIIPVLILVAVAIPSFR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHH
TLRTQLSDPKADLVVKVVGHAWYWSYVYPAEGDKGGFTFDANVDEEQQPKLLATDNDMVI
HHHHHCCCCHHHHHHHHHHCCEEEEEEECCCCCCCCEEEECCCCCCCCCCEEECCCCEEE
PVGKVVKVQVTSDDVIHSWAIPSFGGKIDAIPGRLNQWWFKADREGTYHGQCSELCGARH
ECCCEEEEEECCCCCCCEECCCCCCCEEECCCCCCCHHHEECCCCCCCCCCHHHHHCCCC
AYMPITVRVVSEQAYADWLTEAKTKYAAIDNGARLADAR
CCCEEEEEEECHHHHHHHHHHHHHHEEEECCCCCCCCCC
>Mature Secondary Structure
MRTTQAQHRSSWGLAAFGALLGSSSSALAAGIGQPEPWQMSRQIPVTAEAADLLNFEHGL
CCCCCCHHHCCCCHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
HWIAFAISVFVLVLILYCIFKFNEKTNPTPSRTTHNTAIEVAWTIIPVLILVAVAIPSFR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHH
TLRTQLSDPKADLVVKVVGHAWYWSYVYPAEGDKGGFTFDANVDEEQQPKLLATDNDMVI
HHHHHCCCCHHHHHHHHHHCCEEEEEEECCCCCCCCEEEECCCCCCCCCCEEECCCCEEE
PVGKVVKVQVTSDDVIHSWAIPSFGGKIDAIPGRLNQWWFKADREGTYHGQCSELCGARH
ECCCEEEEEECCCCCCCEECCCCCCCEEECCCCCCCHHHEECCCCCCCCCCHHHHHCCCC
AYMPITVRVVSEQAYADWLTEAKTKYAAIDNGARLADAR
CCCEEEEEEECHHHHHHHHHHHHHHEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2820725; 7651515; 9380672 [H]